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The map label for this gene is rpiA [H]

Identifier: 197105452

GI number: 197105452

Start: 2222714

End: 2223400

Strand: Reverse

Name: rpiA [H]

Synonym: PHZ_c1989

Alternate gene names: 197105452

Gene position: 2223400-2222714 (Counterclockwise)

Preceding gene: 197105453

Following gene: 197105451

Centisome position: 55.64

GC content: 72.93

Gene sequence:

>687_bases
ATGAGCGACGCCGAGGCGCAGAAGAAGGCCGCGGGCGAAGCCGCCGCGGCGCTGGTCGAGAGCGGCATGGTGGTGGGCCT
GGGCACCGGTTCCACCGCCGCCTGGTTCGTCAGGGCGCTGGCCGCCCGCAAGCTGGACATCGTCGGGGTCCCGACCTCGC
AGGCCACCGGCGAGCTGGCGGCCAGCCTCGGCATCCGCATCGCCGAGCTCGGCGAGACCTCGCAGATCGACCTGACCGTG
GACGGCGCCGACGAGATCGGCCCCGGGCTGTCGCTCATCAAGGGCGGCGGGGCGGCCCTGCTGCGCGAGAAGCTGGTGTG
GGAGGCGTCAAAGCGCTGCGTCGTCATCGCCGACGCCGCCAAGCAGGTCCCGACCCTTGGCAAGTACCCCCTGCCGATCG
AGGTGGTGACCTTCGGCCACCAGACGACGGCCCTGCGGATCTGCGACGCCCTGGCCGAATGCGACGTCGGCGTCGCGCCG
CGCCTGCGCGTCAGGGACGGCCAGCCGGTGCGAACCGACGAGGGAAACCTCATCTATGACGCAGCCTGCGGGCGGATCGA
GGAGCCGGCGGCGCTGGCCGCGGCGCTGAAGAGCGTCACCGGCGTGGTGGACCACGGCCTCTTCCTCGACCTCGCCGACC
GGGCTTTGATCGGCGGCCCCGGCGGCGTCACGACGCTGGAGCCCTAG

Upstream 100 bases:

>100_bases
ACGCCCTGGCGCTCGAGCGCAGCCCCCAGGCCGACAAGGCCGGATGGGCGCGGGCGTTCCGTGAGAAGAAGTCGGCCGAG
AAGGCGGCGAGGGGGAAGAA

Downstream 100 bases:

>100_bases
ACCCCAAGGAGTCCGCGTTGGCCGGATACGACTACGACCTCTTCGTCATCGGCGCCGGTTCGGGCGGCGTGCGCGCGGCC
CGGGTGGCGGCGCTGTCGGG

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MSDAEAQKKAAGEAAAALVESGMVVGLGTGSTAAWFVRALAARKLDIVGVPTSQATGELAASLGIRIAELGETSQIDLTV
DGADEIGPGLSLIKGGGAALLREKLVWEASKRCVVIADAAKQVPTLGKYPLPIEVVTFGHQTTALRICDALAECDVGVAP
RLRVRDGQPVRTDEGNLIYDAACGRIEEPAALAAALKSVTGVVDHGLFLDLADRALIGGPGGVTTLEP

Sequences:

>Translated_228_residues
MSDAEAQKKAAGEAAAALVESGMVVGLGTGSTAAWFVRALAARKLDIVGVPTSQATGELAASLGIRIAELGETSQIDLTV
DGADEIGPGLSLIKGGGAALLREKLVWEASKRCVVIADAAKQVPTLGKYPLPIEVVTFGHQTTALRICDALAECDVGVAP
RLRVRDGQPVRTDEGNLIYDAACGRIEEPAALAAALKSVTGVVDHGLFLDLADRALIGGPGGVTTLEP
>Mature_227_residues
SDAEAQKKAAGEAAAALVESGMVVGLGTGSTAAWFVRALAARKLDIVGVPTSQATGELAASLGIRIAELGETSQIDLTVD
GADEIGPGLSLIKGGGAALLREKLVWEASKRCVVIADAAKQVPTLGKYPLPIEVVTFGHQTTALRICDALAECDVGVAPR
LRVRDGQPVRTDEGNLIYDAACGRIEEPAALAAALKSVTGVVDHGLFLDLADRALIGGPGGVTTLEP

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=236, Percent_Identity=36.4406779661017, Blast_Score=129, Evalue=2e-30,
Organism=Escherichia coli, GI1789280, Length=221, Percent_Identity=44.3438914027149, Blast_Score=155, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17551758, Length=226, Percent_Identity=33.6283185840708, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324669, Length=217, Percent_Identity=33.1797235023041, Blast_Score=107, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281364072, Length=223, Percent_Identity=29.5964125560538, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23289; Mature: 23158

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDAEAQKKAAGEAAAALVESGMVVGLGTGSTAAWFVRALAARKLDIVGVPTSQATGELA
CCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCEEEEECCCCCCHHHHH
ASLGIRIAELGETSQIDLTVDGADEIGPGLSLIKGGGAALLREKLVWEASKRCVVIADAA
HHHCCEEEECCCCCEEEEEECCCHHCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCH
KQVPTLGKYPLPIEVVTFGHQTTALRICDALAECDVGVAPRLRVRDGQPVRTDEGNLIYD
HCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEEE
AACGRIEEPAALAAALKSVTGVVDHGLFLDLADRALIGGPGGVTTLEP
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCEEECCCCCCCCCCC
>Mature Secondary Structure 
SDAEAQKKAAGEAAAALVESGMVVGLGTGSTAAWFVRALAARKLDIVGVPTSQATGELA
CCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHCEEEEECCCCCCHHHHH
ASLGIRIAELGETSQIDLTVDGADEIGPGLSLIKGGGAALLREKLVWEASKRCVVIADAA
HHHCCEEEECCCCCEEEEEECCCHHCCCCCEEEECCCHHHHHHHHHHHCCCCEEEEECCH
KQVPTLGKYPLPIEVVTFGHQTTALRICDALAECDVGVAPRLRVRDGQPVRTDEGNLIYD
HCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEEE
AACGRIEEPAALAAALKSVTGVVDHGLFLDLADRALIGGPGGVTTLEP
CCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA