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The map label for this gene is btuE [C]

Identifier: 197105444

GI number: 197105444

Start: 2213610

End: 2214089

Strand: Reverse

Name: btuE [C]

Synonym: PHZ_c1981

Alternate gene names: 197105444

Gene position: 2214089-2213610 (Counterclockwise)

Preceding gene: 197105445

Following gene: 197105443

Centisome position: 55.4

GC content: 68.12

Gene sequence:

>480_bases
ATGACCGCCAGCGCCCACGAGTTTTCCTTCACCACCATCGACGGCGAGCCGCTGCCGCTCACCACCTTCCGCGACAAGGT
GGTGCTGGTGGTCAACACCGCCTCGCAGTGCGGGCTGACGCCGCAGTACGACGGGCTGGAGAAGCTGTACGCCGAGTACC
GCGGCCGCGGCTTCGTGGTGCTGGGCGTGCCCTGCAACCAGTTCGCCGGCCAGGAGCCCGGGGCCGAGGCCGAGATCAAA
GACTTCTGCGAGACCCGGTTCGGCGTCGACTTCCCCCTGACGGCCAAGGTCGAGGTGAAAGGCGAGGGGGCCCATCCCTT
CTACCGCTGGGCCCAGGAGCAGCTCGGCGAGCCGGCCGTGCCGGTGTGGAATTTCCACAAGATCCTGATCGGCAAGTCGG
GCGAGGCGCTGCAGGCGTTCGGGCCGCGCACCGATCCGCTGGATTCCGACATCACCGACGCGATCGAGAGGGCGCTCTGA

Upstream 100 bases:

>100_bases
CGATCCGCGCCCTCGACCTGGCCATCGCCGTCGAACAGGCGTTGGAGGACGCTGCGTAACGGCGCTAGCCTTGCGTCCCA
GGTCCTCCAGGGAGGTCGCC

Downstream 100 bases:

>100_bases
GCGAGGCCGTCGCCCGTTCGCTGGATCTGCTCGCCGAACGGGCGGGCGATCCGGCCCCGCTGGTCTACCGGCGGCTGTTC
GAGGCGTTCCCCGAGATGGA

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MTASAHEFSFTTIDGEPLPLTTFRDKVVLVVNTASQCGLTPQYDGLEKLYAEYRGRGFVVLGVPCNQFAGQEPGAEAEIK
DFCETRFGVDFPLTAKVEVKGEGAHPFYRWAQEQLGEPAVPVWNFHKILIGKSGEALQAFGPRTDPLDSDITDAIERAL

Sequences:

>Translated_159_residues
MTASAHEFSFTTIDGEPLPLTTFRDKVVLVVNTASQCGLTPQYDGLEKLYAEYRGRGFVVLGVPCNQFAGQEPGAEAEIK
DFCETRFGVDFPLTAKVEVKGEGAHPFYRWAQEQLGEPAVPVWNFHKILIGKSGEALQAFGPRTDPLDSDITDAIERAL
>Mature_158_residues
TASAHEFSFTTIDGEPLPLTTFRDKVVLVVNTASQCGLTPQYDGLEKLYAEYRGRGFVVLGVPCNQFAGQEPGAEAEIKD
FCETRFGVDFPLTAKVEVKGEGAHPFYRWAQEQLGEPAVPVWNFHKILIGKSGEALQAFGPRTDPLDSDITDAIERAL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI75709200, Length=151, Percent_Identity=41.0596026490066, Blast_Score=107, Evalue=3e-24,
Organism=Homo sapiens, GI90903240, Length=151, Percent_Identity=41.0596026490066, Blast_Score=107, Evalue=6e-24,
Organism=Homo sapiens, GI15618997, Length=138, Percent_Identity=38.4057971014493, Blast_Score=104, Evalue=4e-23,
Organism=Homo sapiens, GI90903238, Length=131, Percent_Identity=41.2213740458015, Blast_Score=90, Evalue=9e-19,
Organism=Homo sapiens, GI192455698, Length=140, Percent_Identity=34.2857142857143, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI41406084, Length=173, Percent_Identity=34.1040462427746, Blast_Score=78, Evalue=3e-15,
Organism=Homo sapiens, GI6006001, Length=182, Percent_Identity=34.6153846153846, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI32967607, Length=189, Percent_Identity=30.6878306878307, Blast_Score=74, Evalue=6e-14,
Organism=Homo sapiens, GI33186887, Length=182, Percent_Identity=30.2197802197802, Blast_Score=67, Evalue=8e-12,
Organism=Homo sapiens, GI4557629, Length=151, Percent_Identity=32.4503311258278, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1788003, Length=169, Percent_Identity=43.7869822485207, Blast_Score=140, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17506887, Length=162, Percent_Identity=37.037037037037, Blast_Score=119, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17535473, Length=160, Percent_Identity=38.125, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71993584, Length=160, Percent_Identity=34.375, Blast_Score=109, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI193210707, Length=152, Percent_Identity=34.8684210526316, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17550320, Length=180, Percent_Identity=28.8888888888889, Blast_Score=83, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI193209493, Length=180, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71993573, Length=95, Percent_Identity=38.9473684210526, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319721, Length=163, Percent_Identity=40.4907975460123, Blast_Score=140, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6322228, Length=149, Percent_Identity=42.2818791946309, Blast_Score=134, Evalue=7e-33,
Organism=Saccharomyces cerevisiae, GI6322826, Length=146, Percent_Identity=38.3561643835616, Blast_Score=125, Evalue=3e-30,
Organism=Drosophila melanogaster, GI24656777, Length=162, Percent_Identity=40.1234567901235, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24656767, Length=165, Percent_Identity=40, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24656772, Length=165, Percent_Identity=40, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI85726443, Length=158, Percent_Identity=36.0759493670886, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 17465; Mature: 17334

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASAHEFSFTTIDGEPLPLTTFRDKVVLVVNTASQCGLTPQYDGLEKLYAEYRGRGFVV
CCCCCCCEEEEEECCCCCCEEECCCEEEEEEECHHHCCCCCCCCCHHHHHHHHCCCEEEE
LGVPCNQFAGQEPGAEAEIKDFCETRFGVDFPLTAKVEVKGEGAHPFYRWAQEQLGEPAV
ECCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCC
PVWNFHKILIGKSGEALQAFGPRTDPLDSDITDAIERAL
CCCCCEEEEEECCCCCHHHCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TASAHEFSFTTIDGEPLPLTTFRDKVVLVVNTASQCGLTPQYDGLEKLYAEYRGRGFVV
CCCCCCEEEEEECCCCCCEEECCCEEEEEEECHHHCCCCCCCCCHHHHHHHHCCCEEEE
LGVPCNQFAGQEPGAEAEIKDFCETRFGVDFPLTAKVEVKGEGAHPFYRWAQEQLGEPAV
ECCCHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCC
PVWNFHKILIGKSGEALQAFGPRTDPLDSDITDAIERAL
CCCCCEEEEEECCCCCHHHCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]