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The map label for this gene is betT [C]

Identifier: 197105405

GI number: 197105405

Start: 2173606

End: 2175537

Strand: Reverse

Name: betT [C]

Synonym: PHZ_c1942

Alternate gene names: 197105405

Gene position: 2175537-2173606 (Counterclockwise)

Preceding gene: 197105408

Following gene: 197105404

Centisome position: 54.44

GC content: 71.53

Gene sequence:

>1932_bases
ATGGTCAAGTCGGTGATGAATCCGCGGGTCTTCTGGGGCGCGAGCCTGATCGTAGGGCTGCTGCTGGCGGTCGCCGTGGC
CGCGCCCGGCGCGTCGGACCGGGTCTTCCAGGCCGCCCAGGGCTGGGTCATCGGGGCGTTCGGCTGGTTCTACGTGGCGG
CCGTCGCGGGCTTCCTGTTCGTTGTCCTGGGGCTGGCGTTCAGCTCGACGGGCCGCCTGAAGCTCGGCCCTGACGATTCG
GAGCCAGACTTCCCCTACGCCTCGTGGCTGGCGATGCTGTTCGCCGCCGGCATGGGCATCGGCCTGATGTACTTCGCCGT
CGCCGAGCCCGTGCAGCACTACGCCGCCCCGCCGGAGGCCGCGCCCGGCACGTTCGCCGCCGCGCGCGAGGCGATGGTGA
TCACCTTCGTCCACTGGGGCGTCCACGCCTGGGCCGTCTACGCGGTGGTGGGCCTCAGCCTGGCGTTCTTCGCGCACCGC
AAGGGCCTGCCGCTGACCCTGCGCTCGGGCCTCTATCCGCTGCTCGGGCGGCGGATCCACGGGCCGATCGGCGATGCGGT
CGACATCTTCGCCATCTGGGGGACGCTGTTCGGGATCGCTACCTCGCTCGGCCTGGGCGTCGCCCAGATCAACAGCGGTC
TCGCCTACCTCGTCGGGCTTCCGTCCAACCCCGCCGTGCAGGTCGGCTTGATCGTCGTCGTCATGGGCGCCGCGATGGTC
TCGGTGCTGACCGGGCTCGATCGCGGCGTGCGCCGCCTCTCGGAGCTGAACCTGGCGCTCGCCGTCTGCCTGATGGCCTT
CGTCCTCGCCGTGGGGCCGACCGGCTTCCTGCTCAAGGCGCTGGTCCAGAACTTCGGTCTCTACCTCGACCACTTCTTCG
TGCGCACGTTCAACCTCTACGCCTACGAGCCGCGCGGCTGGATGGCGAACTGGACGCTGTTCTACTGGGCCTGGTGGATC
GCCTGGTCGCCGTTCGTGGGGATGTTCATCGCCCGCATCTCCCGGGGCCGCACCGTCCGCGAGTTCGTCGTGGGCGTGCT
GCTCGTCCCGACCGGCTTCACCTTCCTCTGGATGACCGTCTTCGGGAACACCGCCATCAGCCTCGACATGGGCGGGGCGG
CCGGCGCCATCTCGCAGGCGGTGACGTCGGACCTGTCGACGGCGCTCTTCCGCTTCTTCGAGTTCCTGCCGGGCGCGGCG
ATCACCTCGACGCTCGCCGTGCTGCTGGTGGCCGTATTCTTCGTCACCTCGGCCGATTCCGGCTCGCTCGTCATCGACAC
CATCGCCTCGGGCGGCGCCGAGGAGACCCCTCGTTGGCAGCGGGTCTACTGGTGCTCCCTCGAGGGCGGGGCGGCGGCGC
TGCTGCTGCTGGCGGGCGGCCTCGGCGCGCTGCAGGCCGCGACCCTTGTCGCCGCCTTGCCCTTCGCCCTGATCATGATC
GTGCTCTGCGTGGGGCTGGTGCGCCAGATGAACGCCGACGTGAAGGGCGTGGCGGTCGGACGCGAGGCGCCGGCGCTGCG
GGTGCGGCTCGCCCAGATCCTCTCGCCGCCGCGGAAGGCCGAAATCGAGCGGCAGATCGCGGAGGAGGGGGCGCCCGCGC
TGCGCGACGTGGGCGCCGCCCTCGAGGCCGAAGGGCTGCCCGGCCTTCACGTCGCCTTCGCCGAGGACGAGGCGCGGCTC
GACGTGGGCCCGACGGGCGGCGAGGCGGCGGGCCGCTTCGTGTACCGCCTCACGCCCGAGGCGCGGCCGCTGCCGGCCTA
CTCGCATCTGGAGGCGCCGGACGGACGCCGTACCCGGGAATGGCGTCTGATCGCCCGTGTGGAGCCGCGAGGGTTGCGCC
GGGACGTGACGGGTCTGAGCCGCCGCCAGCTCGTCAACGACGTGCTCGAGCAACTCGCCGACTGGCGCGGCGCCGGGCCT
GGACCTAGATAG

Upstream 100 bases:

>100_bases
GCCGCCTCCATCCCTCCGCGGCGTCGGCCGCTCAAGGCCCGAGGGAACGCGAGGTCCGATTTGCGCGGGAACGCCCGCGG
CGGCCCGGCGCTTTCCGCGA

Downstream 100 bases:

>100_bases
GGACCTCCAGCCGGGAGGATATCGACCATGCGCCTGACGACGGACACCCGCTCCGCCCGCCATCTCCACGCGCACCCGGT
CGCCCATGCCTGCCCTCGTC

Product: choline/carnitine/betaine transporter

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MVKSVMNPRVFWGASLIVGLLLAVAVAAPGASDRVFQAAQGWVIGAFGWFYVAAVAGFLFVVLGLAFSSTGRLKLGPDDS
EPDFPYASWLAMLFAAGMGIGLMYFAVAEPVQHYAAPPEAAPGTFAAAREAMVITFVHWGVHAWAVYAVVGLSLAFFAHR
KGLPLTLRSGLYPLLGRRIHGPIGDAVDIFAIWGTLFGIATSLGLGVAQINSGLAYLVGLPSNPAVQVGLIVVVMGAAMV
SVLTGLDRGVRRLSELNLALAVCLMAFVLAVGPTGFLLKALVQNFGLYLDHFFVRTFNLYAYEPRGWMANWTLFYWAWWI
AWSPFVGMFIARISRGRTVREFVVGVLLVPTGFTFLWMTVFGNTAISLDMGGAAGAISQAVTSDLSTALFRFFEFLPGAA
ITSTLAVLLVAVFFVTSADSGSLVIDTIASGGAEETPRWQRVYWCSLEGGAAALLLLAGGLGALQAATLVAALPFALIMI
VLCVGLVRQMNADVKGVAVGREAPALRVRLAQILSPPRKAEIERQIAEEGAPALRDVGAALEAEGLPGLHVAFAEDEARL
DVGPTGGEAAGRFVYRLTPEARPLPAYSHLEAPDGRRTREWRLIARVEPRGLRRDVTGLSRRQLVNDVLEQLADWRGAGP
GPR

Sequences:

>Translated_643_residues
MVKSVMNPRVFWGASLIVGLLLAVAVAAPGASDRVFQAAQGWVIGAFGWFYVAAVAGFLFVVLGLAFSSTGRLKLGPDDS
EPDFPYASWLAMLFAAGMGIGLMYFAVAEPVQHYAAPPEAAPGTFAAAREAMVITFVHWGVHAWAVYAVVGLSLAFFAHR
KGLPLTLRSGLYPLLGRRIHGPIGDAVDIFAIWGTLFGIATSLGLGVAQINSGLAYLVGLPSNPAVQVGLIVVVMGAAMV
SVLTGLDRGVRRLSELNLALAVCLMAFVLAVGPTGFLLKALVQNFGLYLDHFFVRTFNLYAYEPRGWMANWTLFYWAWWI
AWSPFVGMFIARISRGRTVREFVVGVLLVPTGFTFLWMTVFGNTAISLDMGGAAGAISQAVTSDLSTALFRFFEFLPGAA
ITSTLAVLLVAVFFVTSADSGSLVIDTIASGGAEETPRWQRVYWCSLEGGAAALLLLAGGLGALQAATLVAALPFALIMI
VLCVGLVRQMNADVKGVAVGREAPALRVRLAQILSPPRKAEIERQIAEEGAPALRDVGAALEAEGLPGLHVAFAEDEARL
DVGPTGGEAAGRFVYRLTPEARPLPAYSHLEAPDGRRTREWRLIARVEPRGLRRDVTGLSRRQLVNDVLEQLADWRGAGP
GPR
>Mature_643_residues
MVKSVMNPRVFWGASLIVGLLLAVAVAAPGASDRVFQAAQGWVIGAFGWFYVAAVAGFLFVVLGLAFSSTGRLKLGPDDS
EPDFPYASWLAMLFAAGMGIGLMYFAVAEPVQHYAAPPEAAPGTFAAAREAMVITFVHWGVHAWAVYAVVGLSLAFFAHR
KGLPLTLRSGLYPLLGRRIHGPIGDAVDIFAIWGTLFGIATSLGLGVAQINSGLAYLVGLPSNPAVQVGLIVVVMGAAMV
SVLTGLDRGVRRLSELNLALAVCLMAFVLAVGPTGFLLKALVQNFGLYLDHFFVRTFNLYAYEPRGWMANWTLFYWAWWI
AWSPFVGMFIARISRGRTVREFVVGVLLVPTGFTFLWMTVFGNTAISLDMGGAAGAISQAVTSDLSTALFRFFEFLPGAA
ITSTLAVLLVAVFFVTSADSGSLVIDTIASGGAEETPRWQRVYWCSLEGGAAALLLLAGGLGALQAATLVAALPFALIMI
VLCVGLVRQMNADVKGVAVGREAPALRVRLAQILSPPRKAEIERQIAEEGAPALRDVGAALEAEGLPGLHVAFAEDEARL
DVGPTGGEAAGRFVYRLTPEARPLPAYSHLEAPDGRRTREWRLIARVEPRGLRRDVTGLSRRQLVNDVLEQLADWRGAGP
GPR

Specific function: High-Affinity Uptake Of Choline Driven By A Proton- Motive Force. [C]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=649, Percent_Identity=38.9830508474576, Blast_Score=447, Evalue=1e-126,
Organism=Escherichia coli, GI1788102, Length=439, Percent_Identity=29.3849658314351, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1786224, Length=499, Percent_Identity=26.8537074148297, Blast_Score=171, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 68669; Mature: 68669

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS01303 BCCT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKSVMNPRVFWGASLIVGLLLAVAVAAPGASDRVFQAAQGWVIGAFGWFYVAAVAGFLF
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHH
VVLGLAFSSTGRLKLGPDDSEPDFPYASWLAMLFAAGMGIGLMYFAVAEPVQHYAAPPEA
HHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APGTFAAAREAMVITFVHWGVHAWAVYAVVGLSLAFFAHRKGLPLTLRSGLYPLLGRRIH
CCCCHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCHHHHCCHHC
GPIGDAVDIFAIWGTLFGIATSLGLGVAQINSGLAYLVGLPSNPAVQVGLIVVVMGAAMV
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
SVLTGLDRGVRRLSELNLALAVCLMAFVLAVGPTGFLLKALVQNFGLYLDHFFVRTFNLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEE
AYEPRGWMANWTLFYWAWWIAWSPFVGMFIARISRGRTVREFVVGVLLVPTGFTFLWMTV
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHH
FGNTAISLDMGGAAGAISQAVTSDLSTALFRFFEFLPGAAITSTLAVLLVAVFFVTSADS
HCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
GSLVIDTIASGGAEETPRWQRVYWCSLEGGAAALLLLAGGLGALQAATLVAALPFALIMI
CCEEEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VLCVGLVRQMNADVKGVAVGREAPALRVRLAQILSPPRKAEIERQIAEEGAPALRDVGAA
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHH
LEAEGLPGLHVAFAEDEARLDVGPTGGEAAGRFVYRLTPEARPLPAYSHLEAPDGRRTRE
HHCCCCCCEEEEEECCCCCEECCCCCCHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
WRLIARVEPRGLRRDVTGLSRRQLVNDVLEQLADWRGAGPGPR
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MVKSVMNPRVFWGASLIVGLLLAVAVAAPGASDRVFQAAQGWVIGAFGWFYVAAVAGFLF
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCEEEHHHHHHHHHHHHHHH
VVLGLAFSSTGRLKLGPDDSEPDFPYASWLAMLFAAGMGIGLMYFAVAEPVQHYAAPPEA
HHHHHHHCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APGTFAAAREAMVITFVHWGVHAWAVYAVVGLSLAFFAHRKGLPLTLRSGLYPLLGRRIH
CCCCHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCHHHHCCHHC
GPIGDAVDIFAIWGTLFGIATSLGLGVAQINSGLAYLVGLPSNPAVQVGLIVVVMGAAMV
CCCCCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHH
SVLTGLDRGVRRLSELNLALAVCLMAFVLAVGPTGFLLKALVQNFGLYLDHFFVRTFNLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEE
AYEPRGWMANWTLFYWAWWIAWSPFVGMFIARISRGRTVREFVVGVLLVPTGFTFLWMTV
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHH
FGNTAISLDMGGAAGAISQAVTSDLSTALFRFFEFLPGAAITSTLAVLLVAVFFVTSADS
HCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
GSLVIDTIASGGAEETPRWQRVYWCSLEGGAAALLLLAGGLGALQAATLVAALPFALIMI
CCEEEEECCCCCCCCCCCEEEEEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
VLCVGLVRQMNADVKGVAVGREAPALRVRLAQILSPPRKAEIERQIAEEGAPALRDVGAA
HHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHH
LEAEGLPGLHVAFAEDEARLDVGPTGGEAAGRFVYRLTPEARPLPAYSHLEAPDGRRTRE
HHCCCCCCEEEEEECCCCCEECCCCCCHHHCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
WRLIARVEPRGLRRDVTGLSRRQLVNDVLEQLADWRGAGPGPR
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]