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The map label for this gene is ampR [H]

Identifier: 197105393

GI number: 197105393

Start: 2163605

End: 2164549

Strand: Reverse

Name: ampR [H]

Synonym: PHZ_c1930

Alternate gene names: 197105393

Gene position: 2164549-2163605 (Counterclockwise)

Preceding gene: 197105394

Following gene: 197105391

Centisome position: 54.16

GC content: 73.97

Gene sequence:

>945_bases
ATGCAAGACCCGCTCGCCAGCATTCCGCTCAGCGCCATCCGCGTGTTCGAGGCCGCCGCCCGCCTGGGCAGCTTCACGCG
CGCGGCGTCCGAGCTCGGCATGACCCAGGCGGCGGTAAGCTGGCAGGTGAAGGCGCTGGAGCAGCGCCTCGGCCAGCGGC
TGTTCGTGCGCCGCCCGCGCGAGGTCGGCCTGACGCCCGCCGGGGAGCGGCTGGCCCGCGCCGCGTCCGACGCGATGGCG
GCGCTGCGCTCGGCCCTGTCCGACATCTCGGAGACGGGGGAGGGGATGCTCGGCATCACCACCCTGCAGACTTTCGCCAC
CCAGTGGCTCGCCGGACGCCTCGGGCGTTTCCAGCTCGCCCATCCGAAGATCGCGGTGCGGCTCGACACCGAGAACCGCG
TGGTCGACCTGATGCGCGAGGATTTCGACGTCGCCATTCGCGGCGGGCGCGGGGACTGGCCGGGGATGGAGTCCCTGCTG
CTGTTCCCGGCGGTGCAGACGGTGCTCTGCACCCCGGCCGCCGCCGCCCGGCTGGGCGATCCGCCGCGGCCCGAGGCGCT
GTTCGACGTGCACCGGATCGGCTCCGACGCCGAGTGGCGCCAGTGGTTCGCCGCCGCGGGCGTCATGCCCGAGGGCGAGA
CGGGCCCTGCGGCGCCGCGCCTGATGGGCGACACCCAGACCCTGGAGGTGGCCGCCGCCATCGCCGACGACGGCGCGGCC
ATGGGCTCTCCCGTCATGTTCGGCCGCGACCTGGCGGAGGGGCGGCTGGTTCAGCCGTTCGACGTCTACTTCGGCGACAG
CAGCTACTGGCTGGTCTATCCGCGCGACCGCCGGCGGGCGGGCAAGATCGCCGCCTTCCGCGACTGGCTGTTCCAGGAAG
TGGCGGCCGATCCCCACGCCCAGAGGGTCCTGGCGCGGCTCGACCTCGTGGCCGCCGCTAGCTGA

Upstream 100 bases:

>100_bases
TGACCCGCTCCATCGGTTCGACTTGCTGATGGAGTGCAGAATGGTTGCGGGAACGCCGATCGACAAACGGGTTCTCCTGC
TCTATCGATAAGCAGACCTT

Downstream 100 bases:

>100_bases
TCTTCAGGACCGCCGCCTCTTCGGACGGCGGCATCGGCTCGGGCGCGACGCCCAGCAGCGCCGGCACGATGTCCTCGACC
CGCTCGACCGAGATCCACGC

Product: transcriptional regulator, LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MQDPLASIPLSAIRVFEAAARLGSFTRAASELGMTQAAVSWQVKALEQRLGQRLFVRRPREVGLTPAGERLARAASDAMA
ALRSALSDISETGEGMLGITTLQTFATQWLAGRLGRFQLAHPKIAVRLDTENRVVDLMREDFDVAIRGGRGDWPGMESLL
LFPAVQTVLCTPAAAARLGDPPRPEALFDVHRIGSDAEWRQWFAAAGVMPEGETGPAAPRLMGDTQTLEVAAAIADDGAA
MGSPVMFGRDLAEGRLVQPFDVYFGDSSYWLVYPRDRRRAGKIAAFRDWLFQEVAADPHAQRVLARLDLVAAAS

Sequences:

>Translated_314_residues
MQDPLASIPLSAIRVFEAAARLGSFTRAASELGMTQAAVSWQVKALEQRLGQRLFVRRPREVGLTPAGERLARAASDAMA
ALRSALSDISETGEGMLGITTLQTFATQWLAGRLGRFQLAHPKIAVRLDTENRVVDLMREDFDVAIRGGRGDWPGMESLL
LFPAVQTVLCTPAAAARLGDPPRPEALFDVHRIGSDAEWRQWFAAAGVMPEGETGPAAPRLMGDTQTLEVAAAIADDGAA
MGSPVMFGRDLAEGRLVQPFDVYFGDSSYWLVYPRDRRRAGKIAAFRDWLFQEVAADPHAQRVLARLDLVAAAS
>Mature_314_residues
MQDPLASIPLSAIRVFEAAARLGSFTRAASELGMTQAAVSWQVKALEQRLGQRLFVRRPREVGLTPAGERLARAASDAMA
ALRSALSDISETGEGMLGITTLQTFATQWLAGRLGRFQLAHPKIAVRLDTENRVVDLMREDFDVAIRGGRGDWPGMESLL
LFPAVQTVLCTPAAAARLGDPPRPEALFDVHRIGSDAEWRQWFAAAGVMPEGETGPAAPRLMGDTQTLEVAAAIADDGAA
MGSPVMFGRDLAEGRLVQPFDVYFGDSSYWLVYPRDRRRAGKIAAFRDWLFQEVAADPHAQRVLARLDLVAAAS

Specific function: This protein is a positive regulator of gene expression of beta-lactamase (AmpC) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789173, Length=293, Percent_Identity=36.8600682593857, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1786448, Length=296, Percent_Identity=32.4324324324324, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1788706, Length=298, Percent_Identity=31.2080536912752, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=27.7027027027027, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI145693193, Length=300, Percent_Identity=27.6666666666667, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787128, Length=186, Percent_Identity=34.9462365591398, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1787589, Length=288, Percent_Identity=29.8611111111111, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI87081978, Length=293, Percent_Identity=27.9863481228669, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI157672245, Length=156, Percent_Identity=33.974358974359, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789440, Length=294, Percent_Identity=24.1496598639456, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787601, Length=149, Percent_Identity=32.2147651006711, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790262, Length=117, Percent_Identity=34.1880341880342, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=144, Percent_Identity=29.8611111111111, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1786713, Length=85, Percent_Identity=40, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788748, Length=148, Percent_Identity=31.7567567567568, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789639, Length=213, Percent_Identity=28.169014084507, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1790208, Length=170, Percent_Identity=30, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34084; Mature: 34084

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDPLASIPLSAIRVFEAAARLGSFTRAASELGMTQAAVSWQVKALEQRLGQRLFVRRPR
CCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCH
EVGLTPAGERLARAASDAMAALRSALSDISETGEGMLGITTLQTFATQWLAGRLGRFQLA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCEEEC
HPKIAVRLDTENRVVDLMREDFDVAIRGGRGDWPGMESLLLFPAVQTVLCTPAAAARLGD
CCEEEEEECCCHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCC
PPRPEALFDVHRIGSDAEWRQWFAAAGVMPEGETGPAAPRLMGDTQTLEVAAAIADDGAA
CCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
MGSPVMFGRDLAEGRLVQPFDVYFGDSSYWLVYPRDRRRAGKIAAFRDWLFQEVAADPHA
CCCCCCCCCHHCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHH
QRVLARLDLVAAAS
HHHHHHHHHHHCCC
>Mature Secondary Structure
MQDPLASIPLSAIRVFEAAARLGSFTRAASELGMTQAAVSWQVKALEQRLGQRLFVRRPR
CCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCH
EVGLTPAGERLARAASDAMAALRSALSDISETGEGMLGITTLQTFATQWLAGRLGRFQLA
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCEEEC
HPKIAVRLDTENRVVDLMREDFDVAIRGGRGDWPGMESLLLFPAVQTVLCTPAAAARLGD
CCEEEEEECCCHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCC
PPRPEALFDVHRIGSDAEWRQWFAAAGVMPEGETGPAAPRLMGDTQTLEVAAAIADDGAA
CCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCC
MGSPVMFGRDLAEGRLVQPFDVYFGDSSYWLVYPRDRRRAGKIAAFRDWLFQEVAADPHA
CCCCCCCCCHHCCCCCCCCEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCHHH
QRVLARLDLVAAAS
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8064842 [H]