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The map label for this gene is ycbL [H]

Identifier: 197105365

GI number: 197105365

Start: 2129188

End: 2129865

Strand: Direct

Name: ycbL [H]

Synonym: PHZ_c1902

Alternate gene names: 197105365

Gene position: 2129188-2129865 (Clockwise)

Preceding gene: 197105364

Following gene: 197105366

Centisome position: 53.28

GC content: 70.65

Gene sequence:

>678_bases
ATGAACGCTCCGCAGCCGACCCTTCCGATCCGCGCCGTCATCGCGCCGGTCACCCCGCTCCAGCAGAACTGCACCATCGT
CTGGTGCGTGAAGACGATGAAGGCCGCCGTCATCGATCCCGGCGGCGAGGTCCCGCGCCTGCTGCAGGCGCTGAAGGACC
AGGGCCTGACGCTGGAGAAGATCTGGATCACCCACGGCCACCTGGACCACGCCGGCGGCACGGCGGCCCTGAAGGAGGCC
ACCGGCGCGCCCATCGAAGGCCCCCACCCCGACGACGCCTTCTGGATCGAGGACATCGAGAGCTCGGGCGCCCGCTGGGG
CATGCCCGACGCGCGCAGCTTCATCCCGGACCGCTGGCTGCAGGACGGCGATGTCGTCACCCTGGGCGAGACCGAGTTCG
AGGTGATCCACTGCCCCGGCCACACGCCCGGCCACGTGGTCTTCTTCCACCGCCAGGCGCGGTTCGCGCAGGTGGGCGAC
GTGCTGTTCCAGGGCTCGATCGGCCGCACCGACTTCCCGCGCGGGAACCACGCCGACCTGATCGCCTCGATCACGAAGAA
GCTGTGGCCGCTGGGCGAGGACGTGCGCTTCGTGCCCGGCCACGGGCCGATGTCGACCTTCGGCCAGGAGCGCCGCAGCA
ACCCCTTCGTCGCGGACGCGGTCCTGGCCGACGAGTAA

Upstream 100 bases:

>100_bases
GCCGGTCCCCGGCCAGCCCGACCGCTAGGCGGCCAAGGAAGGCCCGGGGTTCGCCCCGGGCCTTTTCTTTAGGGGCGCGA
GCCCCGATCATAGGAGCGAC

Downstream 100 bases:

>100_bases
GCGGCGTGACACGCGCGTTTCATCCGAGACATTCGAGCGTTACGGCGCCCGCCCATGCTGGGCGCCATGGAGCTTGCAGC
TGACATGGCCGGCGCCGGGG

Product: glyoxalase II family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MNAPQPTLPIRAVIAPVTPLQQNCTIVWCVKTMKAAVIDPGGEVPRLLQALKDQGLTLEKIWITHGHLDHAGGTAALKEA
TGAPIEGPHPDDAFWIEDIESSGARWGMPDARSFIPDRWLQDGDVVTLGETEFEVIHCPGHTPGHVVFFHRQARFAQVGD
VLFQGSIGRTDFPRGNHADLIASITKKLWPLGEDVRFVPGHGPMSTFGQERRSNPFVADAVLADE

Sequences:

>Translated_225_residues
MNAPQPTLPIRAVIAPVTPLQQNCTIVWCVKTMKAAVIDPGGEVPRLLQALKDQGLTLEKIWITHGHLDHAGGTAALKEA
TGAPIEGPHPDDAFWIEDIESSGARWGMPDARSFIPDRWLQDGDVVTLGETEFEVIHCPGHTPGHVVFFHRQARFAQVGD
VLFQGSIGRTDFPRGNHADLIASITKKLWPLGEDVRFVPGHGPMSTFGQERRSNPFVADAVLADE
>Mature_225_residues
MNAPQPTLPIRAVIAPVTPLQQNCTIVWCVKTMKAAVIDPGGEVPRLLQALKDQGLTLEKIWITHGHLDHAGGTAALKEA
TGAPIEGPHPDDAFWIEDIESSGARWGMPDARSFIPDRWLQDGDVVTLGETEFEVIHCPGHTPGHVVFFHRQARFAQVGD
VLFQGSIGRTDFPRGNHADLIASITKKLWPLGEDVRFVPGHGPMSTFGQERRSNPFVADAVLADE

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family [H]

Homologues:

Organism=Homo sapiens, GI41327741, Length=214, Percent_Identity=29.9065420560748, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI42822880, Length=216, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787158, Length=208, Percent_Identity=49.5192307692308, Blast_Score=239, Evalue=9e-65,
Organism=Caenorhabditis elegans, GI17538952, Length=195, Percent_Identity=32.8205128205128, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI221330176, Length=191, Percent_Identity=30.3664921465969, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24667711, Length=209, Percent_Identity=26.7942583732057, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI21356335, Length=209, Percent_Identity=26.7942583732057, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24667703, Length=178, Percent_Identity=29.2134831460674, Blast_Score=67, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279 [H]

Pfam domain/function: PF00753 Lactamase_B [H]

EC number: NA

Molecular weight: Translated: 24558; Mature: 24558

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPQPTLPIRAVIAPVTPLQQNCTIVWCVKTMKAAVIDPGGEVPRLLQALKDQGLTLEK
CCCCCCCCCHHEEEECCCCCCCCCEEEEEECHHHHEEECCCCCHHHHHHHHHHCCCEEEE
IWITHGHLDHAGGTAALKEATGAPIEGPHPDDAFWIEDIESSGARWGMPDARSFIPDRWL
EEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEHHHHHCCCCCCCCCCHHHHCCHHHC
QDGDVVTLGETEFEVIHCPGHTPGHVVFFHRQARFAQVGDVLFQGSIGRTDFPRGNHADL
CCCCEEEECCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCHHH
IASITKKLWPLGEDVRFVPGHGPMSTFGQERRSNPFVADAVLADE
HHHHHHHHCCCCCCCEEECCCCCHHHHHHHHCCCCCEEEEEECCC
>Mature Secondary Structure
MNAPQPTLPIRAVIAPVTPLQQNCTIVWCVKTMKAAVIDPGGEVPRLLQALKDQGLTLEK
CCCCCCCCCHHEEEECCCCCCCCCEEEEEECHHHHEEECCCCCHHHHHHHHHHCCCEEEE
IWITHGHLDHAGGTAALKEATGAPIEGPHPDDAFWIEDIESSGARWGMPDARSFIPDRWL
EEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCEEHHHHHCCCCCCCCCCHHHHCCHHHC
QDGDVVTLGETEFEVIHCPGHTPGHVVFFHRQARFAQVGDVLFQGSIGRTDFPRGNHADL
CCCCEEEECCCCEEEEECCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCHHH
IASITKKLWPLGEDVRFVPGHGPMSTFGQERRSNPFVADAVLADE
HHHHHHHHCCCCCCCEEECCCCCHHHHHHHHCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]