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The map label for this gene is yfnA [H]

Identifier: 197105364

GI number: 197105364

Start: 2127568

End: 2129115

Strand: Direct

Name: yfnA [H]

Synonym: PHZ_c1901

Alternate gene names: 197105364

Gene position: 2127568-2129115 (Clockwise)

Preceding gene: 197105362

Following gene: 197105365

Centisome position: 53.24

GC content: 69.12

Gene sequence:

>1548_bases
ATGTGGCGTGTTAAGCCGCTCGACGCGATCCTGGCGACCGCGGAAAAGAAGTCACTGCAAAGGTCGCTCGGCGCATTCCA
GCTCACCATGCTGGGCATCGGCGCCGTCATCGGCACCGGCATCTTCGTCCTGACCGCCGAAGCCGCCCAGAAGGCGGGCC
CCGGCATGATGCTGTCGTTCGTCATCGCCGGCGTGGTCTGCGCGGTGGCTGCGCTCTGCTACGCCGAAATGGCCTCGATG
GTGCCGGTCTCCGGCTCGGCCTACACCTACAGCTACGCCGTGATGGGCGAACTGGTCGCGTGGATGGTCGGCTGGGCGCT
GATCCTGGAGTACGCCGTGGCGGCGGGCGCGGTTTCGGTGGGCTGGTCCGGCTATGTGGTCGGACTGATCGAGGCGAGCT
TCGGCCTCGAGATCCCCGACGCCCTGACGCTCGGGCCGTTCGACGGCGGGATGATCAACCTGCCGGCGATGGCCATCGCC
GGCCTGGTCACCTGGCTGCTGGTGATCGGCACGCGCGAGAGCGCCACGGTCAACGCGATCCTGGTGGCCATCAAGGTGGC
GGCCCTGACGCTGTTCATCGTCCTGGCGGTGCCGGTGATGAACATGGAGCAGTTCACTCCGTTCGCGCCCCTGGGCTTCG
GCGGCATCGCGGCGGCGGCGGCGTCGATCTTCTTCGCCTACGTCGGGTTCGACGCCGTCTCGACGGCGGCCGAGGAAACC
AAGAACCCGCAGCGGAACATGCCCATCGGCCTGATCGGCTCGCTGGCGATCTGCACCATCTTCTACCTGCTGGTGGCCGC
CGGGGTGATCGGCACCGTCGGCGCCCAGCCGGTGTTCAGCCCGACCGGCGAAGCCCTCCACCCGGGTAGCCGCGAGCTCG
CCGCGGCCTGCTCGGCCATCGGCGACGGGGCCGTGGTCTGCTCGAAGGAAGCCCTGGCCTGGACCCTGCGCCAGGTGGGT
TGGCCGCAGATCGGCAACCTGATCGGGCTGGCGGCGGGCCTCGCCCTGCCGTCGGTCATCCTGATGATGATGTTCGGCCA
GACCCGCATCTTCTTCGTGATGAGCCGCGACGGCCTGCTGCCCGCCGCGTTCTCGAAGATCCACCCGAAGTACAACACGC
CCTACGTGATCACGGTCCTGACCGGCATCGCGGTGGCGCTGTTCGCGGCGTTCTTCCCGGTGGGCCAGCTGGCCAACATC
TCGAACTCGGGCACGCTGTTCGCCTTCGCCGCGGTCTCCATCGCGGTCATGGTGATCCGCAAGACCGACCCGACTCGCCA
CCGGCCGTTCCGCACGCCGCTCGTCTTCCTCACCGCTCCGATCGCGGTGGCGGGCTGCCTGTTCCTGTTCGTCAGCCTGG
ACACGAAGAGCATCGTCCTCTTCTGCATCTGGGCGACGGTGGGCCTGGCGGTCTACTTCGGCTACAGCCGCTCCCGCAGC
CACGTGGGCCGGGGCCTCGTCGAGACGCACGAGCTCGACACCGACGCCCCGCCCGGAGCCGTGCCGCCCATGCCGGGCGC
GCCGGTCCCCGGCCAGCCCGACCGCTAG

Upstream 100 bases:

>100_bases
CCCGACCGCCAGCGTTGCCGCTTGACCCGGGGGCGCCAAGCACGCAACGGTCCGCCAAACTTTTTCAACGGCGGCCGGGG
GGCCGCTGCTCGGAGGGAAT

Downstream 100 bases:

>100_bases
GCGGCCAAGGAAGGCCCGGGGTTCGCCCCGGGCCTTTTCTTTAGGGGCGCGAGCCCCGATCATAGGAGCGACATGAACGC
TCCGCAGCCGACCCTTCCGA

Product: amino acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 515

Protein sequence:

>515_residues
MWRVKPLDAILATAEKKSLQRSLGAFQLTMLGIGAVIGTGIFVLTAEAAQKAGPGMMLSFVIAGVVCAVAALCYAEMASM
VPVSGSAYTYSYAVMGELVAWMVGWALILEYAVAAGAVSVGWSGYVVGLIEASFGLEIPDALTLGPFDGGMINLPAMAIA
GLVTWLLVIGTRESATVNAILVAIKVAALTLFIVLAVPVMNMEQFTPFAPLGFGGIAAAAASIFFAYVGFDAVSTAAEET
KNPQRNMPIGLIGSLAICTIFYLLVAAGVIGTVGAQPVFSPTGEALHPGSRELAAACSAIGDGAVVCSKEALAWTLRQVG
WPQIGNLIGLAAGLALPSVILMMMFGQTRIFFVMSRDGLLPAAFSKIHPKYNTPYVITVLTGIAVALFAAFFPVGQLANI
SNSGTLFAFAAVSIAVMVIRKTDPTRHRPFRTPLVFLTAPIAVAGCLFLFVSLDTKSIVLFCIWATVGLAVYFGYSRSRS
HVGRGLVETHELDTDAPPGAVPPMPGAPVPGQPDR

Sequences:

>Translated_515_residues
MWRVKPLDAILATAEKKSLQRSLGAFQLTMLGIGAVIGTGIFVLTAEAAQKAGPGMMLSFVIAGVVCAVAALCYAEMASM
VPVSGSAYTYSYAVMGELVAWMVGWALILEYAVAAGAVSVGWSGYVVGLIEASFGLEIPDALTLGPFDGGMINLPAMAIA
GLVTWLLVIGTRESATVNAILVAIKVAALTLFIVLAVPVMNMEQFTPFAPLGFGGIAAAAASIFFAYVGFDAVSTAAEET
KNPQRNMPIGLIGSLAICTIFYLLVAAGVIGTVGAQPVFSPTGEALHPGSRELAAACSAIGDGAVVCSKEALAWTLRQVG
WPQIGNLIGLAAGLALPSVILMMMFGQTRIFFVMSRDGLLPAAFSKIHPKYNTPYVITVLTGIAVALFAAFFPVGQLANI
SNSGTLFAFAAVSIAVMVIRKTDPTRHRPFRTPLVFLTAPIAVAGCLFLFVSLDTKSIVLFCIWATVGLAVYFGYSRSRS
HVGRGLVETHELDTDAPPGAVPPMPGAPVPGQPDR
>Mature_515_residues
MWRVKPLDAILATAEKKSLQRSLGAFQLTMLGIGAVIGTGIFVLTAEAAQKAGPGMMLSFVIAGVVCAVAALCYAEMASM
VPVSGSAYTYSYAVMGELVAWMVGWALILEYAVAAGAVSVGWSGYVVGLIEASFGLEIPDALTLGPFDGGMINLPAMAIA
GLVTWLLVIGTRESATVNAILVAIKVAALTLFIVLAVPVMNMEQFTPFAPLGFGGIAAAAASIFFAYVGFDAVSTAAEET
KNPQRNMPIGLIGSLAICTIFYLLVAAGVIGTVGAQPVFSPTGEALHPGSRELAAACSAIGDGAVVCSKEALAWTLRQVG
WPQIGNLIGLAAGLALPSVILMMMFGQTRIFFVMSRDGLLPAAFSKIHPKYNTPYVITVLTGIAVALFAAFFPVGQLANI
SNSGTLFAFAAVSIAVMVIRKTDPTRHRPFRTPLVFLTAPIAVAGCLFLFVSLDTKSIVLFCIWATVGLAVYFGYSRSRS
HVGRGLVETHELDTDAPPGAVPPMPGAPVPGQPDR

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=475, Percent_Identity=30.9473684210526, Blast_Score=190, Evalue=3e-48,
Organism=Homo sapiens, GI114326544, Length=452, Percent_Identity=30.5309734513274, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI114326550, Length=452, Percent_Identity=30.5309734513274, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI258614003, Length=442, Percent_Identity=29.8642533936652, Blast_Score=185, Evalue=9e-47,
Organism=Homo sapiens, GI258614005, Length=442, Percent_Identity=29.8642533936652, Blast_Score=184, Evalue=2e-46,
Organism=Homo sapiens, GI258645169, Length=442, Percent_Identity=30.316742081448, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI110347453, Length=425, Percent_Identity=31.7647058823529, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI181337167, Length=431, Percent_Identity=29.9303944315545, Blast_Score=160, Evalue=4e-39,
Organism=Homo sapiens, GI115648063, Length=443, Percent_Identity=24.6049661399549, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI115648022, Length=443, Percent_Identity=24.6049661399549, Blast_Score=106, Evalue=5e-23,
Organism=Homo sapiens, GI186910308, Length=481, Percent_Identity=24.5322245322245, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI186910306, Length=481, Percent_Identity=24.5322245322245, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI186910304, Length=481, Percent_Identity=24.5322245322245, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI33286428, Length=431, Percent_Identity=23.2018561484919, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI7657683, Length=418, Percent_Identity=26.555023923445, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI187423910, Length=432, Percent_Identity=22.9166666666667, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI7657591, Length=432, Percent_Identity=22.9166666666667, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI71979932, Length=267, Percent_Identity=28.0898876404494, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI9790235, Length=329, Percent_Identity=22.4924012158055, Blast_Score=70, Evalue=5e-12,
Organism=Escherichia coli, GI87082250, Length=490, Percent_Identity=26.734693877551, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI87082023, Length=434, Percent_Identity=24.4239631336406, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786302, Length=428, Percent_Identity=23.5981308411215, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788480, Length=253, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081708, Length=371, Percent_Identity=21.832884097035, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1789017, Length=388, Percent_Identity=22.9381443298969, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1786789, Length=269, Percent_Identity=23.4200743494424, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081915, Length=265, Percent_Identity=24.9056603773585, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1786694, Length=265, Percent_Identity=23.3962264150943, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=431, Percent_Identity=31.554524361949, Blast_Score=192, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17533459, Length=436, Percent_Identity=30.5045871559633, Blast_Score=166, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17531343, Length=420, Percent_Identity=28.8095238095238, Blast_Score=149, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17540018, Length=448, Percent_Identity=27.0089285714286, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17568033, Length=439, Percent_Identity=24.373576309795, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI32566699, Length=392, Percent_Identity=22.9591836734694, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17537453, Length=384, Percent_Identity=22.1354166666667, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982608, Length=452, Percent_Identity=22.3451327433628, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71982612, Length=452, Percent_Identity=22.3451327433628, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24667468, Length=426, Percent_Identity=32.8638497652582, Blast_Score=207, Evalue=2e-53,
Organism=Drosophila melanogaster, GI24668806, Length=438, Percent_Identity=30.365296803653, Blast_Score=205, Evalue=6e-53,
Organism=Drosophila melanogaster, GI21356285, Length=438, Percent_Identity=30.365296803653, Blast_Score=205, Evalue=6e-53,
Organism=Drosophila melanogaster, GI24668802, Length=438, Percent_Identity=30.365296803653, Blast_Score=205, Evalue=6e-53,
Organism=Drosophila melanogaster, GI221512776, Length=446, Percent_Identity=32.0627802690583, Blast_Score=202, Evalue=6e-52,
Organism=Drosophila melanogaster, GI24666159, Length=446, Percent_Identity=32.0627802690583, Blast_Score=202, Evalue=6e-52,
Organism=Drosophila melanogaster, GI161077963, Length=439, Percent_Identity=30.5239179954442, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI116007818, Length=446, Percent_Identity=28.6995515695067, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI85725152, Length=446, Percent_Identity=28.6995515695067, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281366235, Length=446, Percent_Identity=28.6995515695067, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI116007820, Length=446, Percent_Identity=28.6995515695067, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI21357367, Length=447, Percent_Identity=25.7270693512304, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI221331183, Length=479, Percent_Identity=25.678496868476, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17647653, Length=479, Percent_Identity=25.678496868476, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24664379, Length=479, Percent_Identity=25.678496868476, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24651635, Length=413, Percent_Identity=24.2130750605327, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24651633, Length=413, Percent_Identity=24.2130750605327, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI45550968, Length=429, Percent_Identity=21.4452214452214, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI19921172, Length=429, Percent_Identity=21.4452214452214, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53644; Mature: 53644

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWRVKPLDAILATAEKKSLQRSLGAFQLTMLGIGAVIGTGIFVLTAEAAQKAGPGMMLSF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHCCCCHHHHH
VIAGVVCAVAALCYAEMASMVPVSGSAYTYSYAVMGELVAWMVGWALILEYAVAAGAVSV
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GWSGYVVGLIEASFGLEIPDALTLGPFDGGMINLPAMAIAGLVTWLLVIGTRESATVNAI
CCCCEEEEEEEHHCCCCCCCCCEECCCCCCEEECHHHHHHHHHHHHHHHCCCCCHHHHHH
LVAIKVAALTLFIVLAVPVMNMEQFTPFAPLGFGGIAAAAASIFFAYVGFDAVSTAAEET
HHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KNPQRNMPIGLIGSLAICTIFYLLVAAGVIGTVGAQPVFSPTGEALHPGSRELAAACSAI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHC
GDGAVVCSKEALAWTLRQVGWPQIGNLIGLAAGLALPSVILMMMFGQTRIFFVMSRDGLL
CCCCEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
PAAFSKIHPKYNTPYVITVLTGIAVALFAAFFPVGQLANISNSGTLFAFAAVSIAVMVIR
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHEE
KTDPTRHRPFRTPLVFLTAPIAVAGCLFLFVSLDTKSIVLFCIWATVGLAVYFGYSRSRS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHH
HVGRGLVETHELDTDAPPGAVPPMPGAPVPGQPDR
HHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MWRVKPLDAILATAEKKSLQRSLGAFQLTMLGIGAVIGTGIFVLTAEAAQKAGPGMMLSF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHCCCCHHHHH
VIAGVVCAVAALCYAEMASMVPVSGSAYTYSYAVMGELVAWMVGWALILEYAVAAGAVSV
HHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GWSGYVVGLIEASFGLEIPDALTLGPFDGGMINLPAMAIAGLVTWLLVIGTRESATVNAI
CCCCEEEEEEEHHCCCCCCCCCEECCCCCCEEECHHHHHHHHHHHHHHHCCCCCHHHHHH
LVAIKVAALTLFIVLAVPVMNMEQFTPFAPLGFGGIAAAAASIFFAYVGFDAVSTAAEET
HHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
KNPQRNMPIGLIGSLAICTIFYLLVAAGVIGTVGAQPVFSPTGEALHPGSRELAAACSAI
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHC
GDGAVVCSKEALAWTLRQVGWPQIGNLIGLAAGLALPSVILMMMFGQTRIFFVMSRDGLL
CCCCEEECHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCC
PAAFSKIHPKYNTPYVITVLTGIAVALFAAFFPVGQLANISNSGTLFAFAAVSIAVMVIR
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCHHHHHHHHHHHHHEE
KTDPTRHRPFRTPLVFLTAPIAVAGCLFLFVSLDTKSIVLFCIWATVGLAVYFGYSRSRS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHH
HVGRGLVETHELDTDAPPGAVPPMPGAPVPGQPDR
HHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]