Click here to switch to the map view.

The map label for this gene is dapE [H]

Identifier: 197105349

GI number: 197105349

Start: 2111427

End: 2112830

Strand: Direct

Name: dapE [H]

Synonym: PHZ_c1886

Alternate gene names: 197105349

Gene position: 2111427-2112830 (Clockwise)

Preceding gene: 197105348

Following gene: 197105354

Centisome position: 52.84

GC content: 71.58

Gene sequence:

>1404_bases
TTGCCCGCCTTCCGGACCTTCGCCGCCGCCGCGGCGCTTTCCGCCGCCCTCGTATCTTCCTTGGGCGCGCCGGCGCTCGC
CGCGCCCAAGGCGGACCCCGCCCTGCACGCCCGGGCGCTGGAGATCCTGACCACCGGCATCGGCTACCGGACGGTGGCGG
GCGGCGACCAGGTCGTCCCCTACGCCGAGTACCTGAAAGGCGTGCTCGTGGCCGGCGGCTTCAAGCCGGAGGAGATCACG
ATCGAGCCCATGAAGGGCACGGCGTACCTGCTCGCCCGCTATCCCGGTCAGGACCCGAAGAAGAAGCCGATCGTCATCTC
GGGCCATATGGACGTGGTCGAGGCCAAGGCGCAGGACTGGACCCGCGATCCGTTCAAGCCGGTGGTGGAGAACGGCTGGA
TCTATGGCCGCGGCGCCGTGGACAACAAGTTCGACGTCTCGATGGTGGTGGCGACCCTGGCCAACCTGCGCCGGCAGGGC
TGGCGGCCCGGCCGCGACGTGATCCTGGCGCTCTCGGGCGACGAGGAGACCACCATGGCCACCACGGCCGCCCTCGCCGA
GCGGCTGAAGCACGCCGAGATGGTGCTGAACTCGGACGGCGGCGGCGGCAGCCTGAAGGACGGCAAGCCCCTGCCCTACG
CCCTGCAGGGCGCCGAGAAGACCTACGCCGACTTCAAGGCGACCTTCACCGACCCCGGCGGCCACTCCAGCCGGCCGACG
CCGACCAACCCGATCTACCGGCTGACCAAGGCCCTGGACCGGCTGGCGGCCTACCGCTTCCCGACCATGAGCAACGAAAT
CACCCGCGCGGCGCTGGCCGCCGAGGGCGCGGCGACGCCGGGCCCGATCGGCGAGGCGCTGAAGGCGTTCGCGAAGAACC
CCGAGGACGCCGCGGCGATCGCCACGCTGTCGGCGACGCCCGACTACAATCCCGTCCTGCGGACCACCTGCGTGGCGACC
ATGGTCGAGGCCGGCCATGCGCCCAACGCCCTGCCCCAGAAGGCCGAGGCGACGGTGAACTGCCGGATCTTCCCCGGGAC
CTCGTCCGAGAGCGTGCGCCAGACGCTGATCGAGGTGATGGCCGAGCCGACGATGACCATCACCCGGGTGGACGACGGCT
CCATCGACAGCCCGGCCTCGCCGCTGCGCCCCGACGTGGTGGCGGCGGTGACGAAGGCGGTGCATGCCCGCTACCCCGGC
CTGGCCATCACGCCGTGGCAGGAATCCGGGGCCTCGGACTCCATGCACTTCCGCGCCCAGGGCGTGCCGAGCTACGGCGT
CTCGGGCCTGTTCATGGAGCAGGGCCAGGCCTTCGCCCACGGGCTGAACGAGAAGGCCCCGGTGGCCGCCATCGACGGCT
CGCTGGCGCACTGGGACTCGCTGCTGCGCGACCTGGCGAAGTAG

Upstream 100 bases:

>100_bases
AGGCTGTCTTCCAGCGCGCCCGGGCGCTGATCGGCCCGGCGGATTGACGCGGGCCCGGGGGGCTCTAGCGTCGCACGGCC
ACGCTTCCACGGAGTCGCCC

Downstream 100 bases:

>100_bases
CCGCCGGGCCGCGCCGGGCGGGCGCCTACTTCGCCCCGGCGATGTAGGCGTCGACGCGCTGCTCCAGGACGTCGAGCGGG
ATGGCGCCCGCCGCCAGCAC

Product: hypothetical protein

Products: NA

Alternate protein names: SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase [H]

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MPAFRTFAAAAALSAALVSSLGAPALAAPKADPALHARALEILTTGIGYRTVAGGDQVVPYAEYLKGVLVAGGFKPEEIT
IEPMKGTAYLLARYPGQDPKKKPIVISGHMDVVEAKAQDWTRDPFKPVVENGWIYGRGAVDNKFDVSMVVATLANLRRQG
WRPGRDVILALSGDEETTMATTAALAERLKHAEMVLNSDGGGGSLKDGKPLPYALQGAEKTYADFKATFTDPGGHSSRPT
PTNPIYRLTKALDRLAAYRFPTMSNEITRAALAAEGAATPGPIGEALKAFAKNPEDAAAIATLSATPDYNPVLRTTCVAT
MVEAGHAPNALPQKAEATVNCRIFPGTSSESVRQTLIEVMAEPTMTITRVDDGSIDSPASPLRPDVVAAVTKAVHARYPG
LAITPWQESGASDSMHFRAQGVPSYGVSGLFMEQGQAFAHGLNEKAPVAAIDGSLAHWDSLLRDLAK

Sequences:

>Translated_467_residues
MPAFRTFAAAAALSAALVSSLGAPALAAPKADPALHARALEILTTGIGYRTVAGGDQVVPYAEYLKGVLVAGGFKPEEIT
IEPMKGTAYLLARYPGQDPKKKPIVISGHMDVVEAKAQDWTRDPFKPVVENGWIYGRGAVDNKFDVSMVVATLANLRRQG
WRPGRDVILALSGDEETTMATTAALAERLKHAEMVLNSDGGGGSLKDGKPLPYALQGAEKTYADFKATFTDPGGHSSRPT
PTNPIYRLTKALDRLAAYRFPTMSNEITRAALAAEGAATPGPIGEALKAFAKNPEDAAAIATLSATPDYNPVLRTTCVAT
MVEAGHAPNALPQKAEATVNCRIFPGTSSESVRQTLIEVMAEPTMTITRVDDGSIDSPASPLRPDVVAAVTKAVHARYPG
LAITPWQESGASDSMHFRAQGVPSYGVSGLFMEQGQAFAHGLNEKAPVAAIDGSLAHWDSLLRDLAK
>Mature_466_residues
PAFRTFAAAAALSAALVSSLGAPALAAPKADPALHARALEILTTGIGYRTVAGGDQVVPYAEYLKGVLVAGGFKPEEITI
EPMKGTAYLLARYPGQDPKKKPIVISGHMDVVEAKAQDWTRDPFKPVVENGWIYGRGAVDNKFDVSMVVATLANLRRQGW
RPGRDVILALSGDEETTMATTAALAERLKHAEMVLNSDGGGGSLKDGKPLPYALQGAEKTYADFKATFTDPGGHSSRPTP
TNPIYRLTKALDRLAAYRFPTMSNEITRAALAAEGAATPGPIGEALKAFAKNPEDAAAIATLSATPDYNPVLRTTCVATM
VEAGHAPNALPQKAEATVNCRIFPGTSSESVRQTLIEVMAEPTMTITRVDDGSIDSPASPLRPDVVAAVTKAVHARYPGL
AITPWQESGASDSMHFRAQGVPSYGVSGLFMEQGQAFAHGLNEKAPVAAIDGSLAHWDSLLRDLAK

Specific function: Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bact

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. DapE subfamily [H]

Homologues:

Organism=Homo sapiens, GI269846968, Length=387, Percent_Identity=27.1317829457364, Blast_Score=101, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6322289, Length=305, Percent_Identity=25.5737704918033, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24649206, Length=358, Percent_Identity=24.0223463687151, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24649212, Length=188, Percent_Identity=29.2553191489362, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001261
- InterPro:   IPR005941
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.18 [H]

Molecular weight: Translated: 49284; Mature: 49153

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAFRTFAAAAALSAALVSSLGAPALAAPKADPALHARALEILTTGIGYRTVAGGDQVVP
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCC
YAEYLKGVLVAGGFKPEEITIEPMKGTAYLLARYPGQDPKKKPIVISGHMDVVEAKAQDW
HHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEECCHHHHHHHHHCC
TRDPFKPVVENGWIYGRGAVDNKFDVSMVVATLANLRRQGWRPGRDVILALSGDEETTMA
CCCCCHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHH
TTAALAERLKHAEMVLNSDGGGGSLKDGKPLPYALQGAEKTYADFKATFTDPGGHSSRPT
HHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHCCCHHHHHCCEEEECCCCCCCCCCC
PTNPIYRLTKALDRLAAYRFPTMSNEITRAALAAEGAATPGPIGEALKAFAKNPEDAAAI
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHEE
ATLSATPDYNPVLRTTCVATMVEAGHAPNALPQKAEATVNCRIFPGTSSESVRQTLIEVM
EEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
AEPTMTITRVDDGSIDSPASPLRPDVVAAVTKAVHARYPGLAITPWQESGASDSMHFRAQ
CCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCEEEEEC
GVPSYGVSGLFMEQGQAFAHGLNEKAPVAAIDGSLAHWDSLLRDLAK
CCCCCCCCCEEHHCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure 
PAFRTFAAAAALSAALVSSLGAPALAAPKADPALHARALEILTTGIGYRTVAGGDQVVP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCC
YAEYLKGVLVAGGFKPEEITIEPMKGTAYLLARYPGQDPKKKPIVISGHMDVVEAKAQDW
HHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEECCHHHHHHHHHCC
TRDPFKPVVENGWIYGRGAVDNKFDVSMVVATLANLRRQGWRPGRDVILALSGDEETTMA
CCCCCHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHHH
TTAALAERLKHAEMVLNSDGGGGSLKDGKPLPYALQGAEKTYADFKATFTDPGGHSSRPT
HHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCHHHCCCHHHHHCCEEEECCCCCCCCCCC
PTNPIYRLTKALDRLAAYRFPTMSNEITRAALAAEGAATPGPIGEALKAFAKNPEDAAAI
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHEE
ATLSATPDYNPVLRTTCVATMVEAGHAPNALPQKAEATVNCRIFPGTSSESVRQTLIEVM
EEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
AEPTMTITRVDDGSIDSPASPLRPDVVAAVTKAVHARYPGLAITPWQESGASDSMHFRAQ
CCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCEEEEEC
GVPSYGVSGLFMEQGQAFAHGLNEKAPVAAIDGSLAHWDSLLRDLAK
CCCCCCCCCEEHHCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA