Click here to switch to the map view.

The map label for this gene is acpS

Identifier: 197105338

GI number: 197105338

Start: 2102290

End: 2102706

Strand: Reverse

Name: acpS

Synonym: PHZ_c1875

Alternate gene names: 197105338

Gene position: 2102706-2102290 (Counterclockwise)

Preceding gene: 197105339

Following gene: 197105337

Centisome position: 52.62

GC content: 70.98

Gene sequence:

>417_bases
GTGATCATCGGCATCGGCTCGGACCTGTCCGACATCCGCCGCATCCAGGCCAGCCTCGACCGCTTCGGCGACCGCTTCCG
GCATCGGGTGTTCACCGAAATCGAGCGCACGCGTTCCGACCGCAAGGCCGACGCCGCCGCCTCCTACGCCAAGCGCTTCG
CCGCCAAGGAGGCCTGCGCCAAGGCCCTGGGCACCGGCATGCGCCGCGGCGTCTTCTGGCGCGACATGGGCGTGGTCAAC
ATGCGCTCGGGGCAGCCGACCATGGCGCTCACCGGCGGGGCGCTGAGGCGGCTGGAGGAGATCACCCCGCCCGGGATGAC
GGCGCATATCCACCTGTCGCTGACCGACGACCATCCCTACGCCCAGGCCTTCGTGATCATCGAGGCGCTGCCCGCCGCCC
CGTCCGCCGCCGAATGA

Upstream 100 bases:

>100_bases
TCGGCCATTTCCTGATCGGCGAGGCGATCTTCATCGGCCTCGGCCCGGCGATCCAGCGCATGCGCGCGCTGATGGACGAG
GCCAGGCGCCAGGTGGCCGC

Downstream 100 bases:

>100_bases
CGGATATCAAGGCGCGGGCGCCCGCCGTCGCCTAGCCCGCCGCTTTCGGCCGGCTTTCCGCCGCCGGCGTCGCGGAAGGA
GCCTGCGGGTGTTGACGGGA

Product: holo-(acyl-carrier-protein) synthase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MIIGIGSDLSDIRRIQASLDRFGDRFRHRVFTEIERTRSDRKADAAASYAKRFAAKEACAKALGTGMRRGVFWRDMGVVN
MRSGQPTMALTGGALRRLEEITPPGMTAHIHLSLTDDHPYAQAFVIIEALPAAPSAAE

Sequences:

>Translated_138_residues
MIIGIGSDLSDIRRIQASLDRFGDRFRHRVFTEIERTRSDRKADAAASYAKRFAAKEACAKALGTGMRRGVFWRDMGVVN
MRSGQPTMALTGGALRRLEEITPPGMTAHIHLSLTDDHPYAQAFVIIEALPAAPSAAE
>Mature_138_residues
MIIGIGSDLSDIRRIQASLDRFGDRFRHRVFTEIERTRSDRKADAAASYAKRFAAKEACAKALGTGMRRGVFWRDMGVVN
MRSGQPTMALTGGALRRLEEITPPGMTAHIHLSLTDDHPYAQAFVIIEALPAAPSAAE

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=128, Percent_Identity=39.84375, Blast_Score=86, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_PHEZH (B4RCU9)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002130715.1
- GeneID:   6791390
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c1875
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   CLSK2803469
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 15157; Mature: 15157

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIGIGSDLSDIRRIQASLDRFGDRFRHRVFTEIERTRSDRKADAAASYAKRFAAKEACA
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGMRRGVFWRDMGVVNMRSGQPTMALTGGALRRLEEITPPGMTAHIHLSLTDDHPY
HHHHHHHHCCCEECCCCEEEECCCCCCEEECHHHHHHHHHCCCCCCEEEEEEEEECCCCH
AQAFVIIEALPAAPSAAE
HHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MIIGIGSDLSDIRRIQASLDRFGDRFRHRVFTEIERTRSDRKADAAASYAKRFAAKEACA
CEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KALGTGMRRGVFWRDMGVVNMRSGQPTMALTGGALRRLEEITPPGMTAHIHLSLTDDHPY
HHHHHHHHCCCEECCCCEEEECCCCCCEEECHHHHHHHHHCCCCCCEEEEEEEEECCCCH
AQAFVIIEALPAAPSAAE
HHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA