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The map label for this gene is aroQ

Identifier: 197105312

GI number: 197105312

Start: 2072505

End: 2072942

Strand: Direct

Name: aroQ

Synonym: PHZ_c1849

Alternate gene names: 197105312

Gene position: 2072505-2072942 (Clockwise)

Preceding gene: 197105308

Following gene: 197105313

Centisome position: 51.86

GC content: 66.67

Gene sequence:

>438_bases
ATGTCGAAACCGATCTATGTGCTGAGCGGTCCCAATCTCAACCTCCTGGGAACCCGCGAGCCCGAGATTTACGGACATCA
GACCCTGGACGACGTCCGCCGCCTCTGCGAGGCGCGTGCGAAGTCCCTGGGGCGCGAGATCGTGTTCCGTCAGTCCAACC
ACGAGGGCGAACTGATCGACTGGATCCAGGAAGCCCGCGAGAAGGCGTGCGCCCTGGTGATCAATCCCGCCGGCTACGGC
CACACCTCGGTGGCCATTCTCGATGCGCTGAAGGCCGTGGGCCTGCCGGTGGTGGAATGCCACCTGTCGAACCCCGCCGC
GCGCGAGACGTTCCGCCGCAAGACGTATGTTTCCCTCGCCGCCACCGGGGTCGTCTCCGGTTTCGGCGCGGCGAGCTATG
AACTGGCCGTCGAGGCCGCCGCGGGCCTGGCCCGCTAA

Upstream 100 bases:

>100_bases
CCGTTGACGGTCAGGTTCATTGCGGCGGTCGCTCCGGTCGGCTTGCTTGTGGCCTCCGCCGCCTCCCGTTACAAGACGCC
GGAATCGACGGCGGAGCCGA

Downstream 100 bases:

>100_bases
TCCAAGCCTACAAGGAAAAGGGTCGTTCCATGGCTAGCAGTCCGAAGGCGCCCGCCGATCCGATCGACGCGCGCCTGGTG
CGCAAACTGGCCGACATCCT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 145; Mature: 144

Protein sequence:

>145_residues
MSKPIYVLSGPNLNLLGTREPEIYGHQTLDDVRRLCEARAKSLGREIVFRQSNHEGELIDWIQEAREKACALVINPAGYG
HTSVAILDALKAVGLPVVECHLSNPAARETFRRKTYVSLAATGVVSGFGAASYELAVEAAAGLAR

Sequences:

>Translated_145_residues
MSKPIYVLSGPNLNLLGTREPEIYGHQTLDDVRRLCEARAKSLGREIVFRQSNHEGELIDWIQEAREKACALVINPAGYG
HTSVAILDALKAVGLPVVECHLSNPAARETFRRKTYVSLAATGVVSGFGAASYELAVEAAAGLAR
>Mature_144_residues
SKPIYVLSGPNLNLLGTREPEIYGHQTLDDVRRLCEARAKSLGREIVFRQSNHEGELIDWIQEAREKACALVINPAGYGH
TSVAILDALKAVGLPVVECHLSNPAARETFRRKTYVSLAATGVVSGFGAASYELAVEAAAGLAR

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_PHEZH (B4RCS3)

Other databases:

- EMBL:   CP000747
- RefSeq:   YP_002130689.1
- GeneID:   6791364
- GenomeReviews:   CP000747_GR
- KEGG:   pzu:PHZ_c1849
- HOGENOM:   HBG284657
- OMA:   EFRQTNH
- ProtClustDB:   PRK05395
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 15646; Mature: 15515

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 24-24 ACT_SITE 101-101 BINDING 75-75 BINDING 81-81 BINDING 88-88 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKPIYVLSGPNLNLLGTREPEIYGHQTLDDVRRLCEARAKSLGREIVFRQSNHEGELID
CCCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCHHEEEECCCCCCHHHH
WIQEAREKACALVINPAGYGHTSVAILDALKAVGLPVVECHLSNPAARETFRRKTYVSLA
HHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
ATGVVSGFGAASYELAVEAAAGLAR
HHHHHHCCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
SKPIYVLSGPNLNLLGTREPEIYGHQTLDDVRRLCEARAKSLGREIVFRQSNHEGELID
CCCEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCHHEEEECCCCCCHHHH
WIQEAREKACALVINPAGYGHTSVAILDALKAVGLPVVECHLSNPAARETFRRKTYVSLA
HHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHH
ATGVVSGFGAASYELAVEAAAGLAR
HHHHHHCCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA