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The map label for this gene is hfq [H]

Identifier: 197105189

GI number: 197105189

Start: 1933064

End: 1933309

Strand: Reverse

Name: hfq [H]

Synonym: PHZ_c1726

Alternate gene names: 197105189

Gene position: 1933309-1933064 (Counterclockwise)

Preceding gene: 197105190

Following gene: 197105188

Centisome position: 48.38

GC content: 59.76

Gene sequence:

>246_bases
ATGAGCGACAAGAAACAGAACCTGCAGGACACCTTCCTGAACAGCGTGCGCAAGTCCAAGACGCCGCTGACGATCTTCCT
GGTGAACGGGGTCAAGCTGCAGGGCGTGGTGAGCTGGTTCGACAACTTCTGCGTTCTGCTCCGCAGGGACGGGCAATCCC
AGCTCGTCTACAAGCACGCCATCTCCACCATCATGCCGGCTCAGCCCGTGCAGCTCTATGAGCCGTCTGACGACGAGGCC
GATTGA

Upstream 100 bases:

>100_bases
ATCGTCCGCCCGCGATTGCGCCCGTCGCCAAAGCCTGTTTAGCGTGACCCTTGTGTGTGGGCGGACCTGGCCGCCCGTCA
TAACCAAAAGGCGAAAAGCC

Downstream 100 bases:

>100_bases
GTTCTTCGAAATCCGTTGACCGTGAGGCGCCCGTCCAGGGCGCCGTGGTGATCCACCCGGACCGCGAGGGCCGGACGAGC
GCCGTACGGGACCCGCAGGC

Product: RNA-binding protein Hfq

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 81; Mature: 80

Protein sequence:

>81_residues
MSDKKQNLQDTFLNSVRKSKTPLTIFLVNGVKLQGVVSWFDNFCVLLRRDGQSQLVYKHAISTIMPAQPVQLYEPSDDEA
D

Sequences:

>Translated_81_residues
MSDKKQNLQDTFLNSVRKSKTPLTIFLVNGVKLQGVVSWFDNFCVLLRRDGQSQLVYKHAISTIMPAQPVQLYEPSDDEA
D
>Mature_80_residues
SDKKQNLQDTFLNSVRKSKTPLTIFLVNGVKLQGVVSWFDNFCVLLRRDGQSQLVYKHAISTIMPAQPVQLYEPSDDEAD

Specific function: RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs [H]

COG id: COG1923

COG function: function code R; Uncharacterized host factor I protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hfq family [H]

Homologues:

Organism=Escherichia coli, GI1790614, Length=70, Percent_Identity=52.8571428571429, Blast_Score=86, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005001
- InterPro:   IPR010920
- InterPro:   IPR001163 [H]

Pfam domain/function: PF01423 LSM [H]

EC number: NA

Molecular weight: Translated: 9215; Mature: 9083

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKKQNLQDTFLNSVRKSKTPLTIFLVNGVKLQGVVSWFDNFCVLLRRDGQSQLVYKHA
CCCCCCHHHHHHHHHHHCCCCCEEEEEECCEEHHHHHHHHHHHEEEEECCCCCHHHHHHH
ISTIMPAQPVQLYEPSDDEAD
HHHHCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
SDKKQNLQDTFLNSVRKSKTPLTIFLVNGVKLQGVVSWFDNFCVLLRRDGQSQLVYKHA
CCCCCHHHHHHHHHHHCCCCCEEEEEECCEEHHHHHHHHHHHEEEEECCCCCHHHHHHH
ISTIMPAQPVQLYEPSDDEAD
HHHHCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA