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The map label for this gene is hflX [H]

Identifier: 197105188

GI number: 197105188

Start: 1931742

End: 1933016

Strand: Reverse

Name: hflX [H]

Synonym: PHZ_c1725

Alternate gene names: 197105188

Gene position: 1933016-1931742 (Counterclockwise)

Preceding gene: 197105189

Following gene: 197105185

Centisome position: 48.37

GC content: 73.02

Gene sequence:

>1275_bases
GTGATCCACCCGGACCGCGAGGGCCGGACGAGCGCCGTACGGGACCCGCAGGCCCGCCTCGAAGAGGCGGTCGGCCTTGC
GCAGGCGCTCGACCTGGAAGTCCGCGAGACCCTGGTCGCGCCCCTGCGGCGGCTGACGCCCGCCACCCTGTTCGGCAAGG
GCAAGGTGGAGGAGGTTGCGGCGGTCGTGGACTCCGTCGAGGCCGACGTGGTGGTCGTCGACGACGCGCTCACGCCGGTC
CAGCAGCGCAACCTCGAGAAGGCCTGGAAGGCCAAGGTCATCGACCGCACGGGGCTGATCCTGGAGATCTTCGCCCGCCG
CGCCCGCACGCGGGAGGGCCGCCTGCAGGTCGAGCTGGCCCGTCTGACCTATGAGCGTTCGCGCCTCGTCCGCACCTGGA
CCCACCTGGAGCGCCAGCGCGGCGGCTTCGGCGTCATGGGCGGCCCGGGCGAAACCCAGATCGAGACCGACCGGCGGCTC
CTGGCCGAGAAGATCGGCAAGCTGAAGCGCGAGCTGGTGGAGGTGCGCCGCACCCGAACCCTGCAGCGCTCGGCCCGCCG
TCGCGTGCCGTACCCGACGGTGGCGCTGGTGGGCTACACCAACGCCGGCAAGTCCACGCTGTTCAACCGCCTGACCCAGG
CCGAGGTGCTGGCGCAGGACATGCTGTTCGCCACCCTCGATCCGACGCTGCGGATGCTGAAGCTGCCCGACGGGCGCCCG
GCGATCCTGTCGGATACCGTGGGCTTCATCTCGGACCTGCCGCACGAGCTGGTCGAGGCGTTCCGCGCCACGCTGGAGGA
GGTGCGCGAGGCCGACGTCGTGCTGCACGTGCGCGACATCGCCAGCGAGGAGACCGAGGCGCAGGCGCAGGACGTGCGGA
CGGTGCTCCAGCGCCTGGGCGTCGACATGGACGAGCGGCGCATCCTGGAGGTCTGGAACAAGGTCGACCTGCTGCCGGCC
GACGAACGCCAGGACGCGGCCGGCGACGCCCGCCGGGCCCATCCGCCGGCCATCCTGGTCTCGGCGGTCACGGGCGAGGG
CTGCGACGACCTCCTGAGGGCCGTCGGCGCGCTGGTGGACGAAGCGCCGCCGGTGGACGTCTATGCGCCGGCCGGGGAGG
GCGCGGCGATCGCCTGGCTCTACCGGCACGGCCGGGTGGTCGAACGGGTGGAGGGCAAGGACGGCAGCGTGCGCCTGGCG
GTCAGCCTCTCGCCCCAGGCGCTGGGCCAGTTCGAACAGCTGTTCCCGCACGCCGAGGTGCGCGGGGCGGGCTGA

Upstream 100 bases:

>100_bases
TGCCGGCTCAGCCCGTGCAGCTCTATGAGCCGTCTGACGACGAGGCCGATTGAGTTCTTCGAAATCCGTTGACCGTGAGG
CGCCCGTCCAGGGCGCCGTG

Downstream 100 bases:

>100_bases
CGCCCGCCTGCACCGAATCTCCACAGTCCGCGCCGGTCGGCCTGCACCGGCGCCGCTCAAAGCTGCGGGCCATGGACGAG
CTCTTCTCCCCCGCGCCCGG

Product: GTP-binding protein HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MIHPDREGRTSAVRDPQARLEEAVGLAQALDLEVRETLVAPLRRLTPATLFGKGKVEEVAAVVDSVEADVVVVDDALTPV
QQRNLEKAWKAKVIDRTGLILEIFARRARTREGRLQVELARLTYERSRLVRTWTHLERQRGGFGVMGGPGETQIETDRRL
LAEKIGKLKRELVEVRRTRTLQRSARRRVPYPTVALVGYTNAGKSTLFNRLTQAEVLAQDMLFATLDPTLRMLKLPDGRP
AILSDTVGFISDLPHELVEAFRATLEEVREADVVLHVRDIASEETEAQAQDVRTVLQRLGVDMDERRILEVWNKVDLLPA
DERQDAAGDARRAHPPAILVSAVTGEGCDDLLRAVGALVDEAPPVDVYAPAGEGAAIAWLYRHGRVVERVEGKDGSVRLA
VSLSPQALGQFEQLFPHAEVRGAG

Sequences:

>Translated_424_residues
MIHPDREGRTSAVRDPQARLEEAVGLAQALDLEVRETLVAPLRRLTPATLFGKGKVEEVAAVVDSVEADVVVVDDALTPV
QQRNLEKAWKAKVIDRTGLILEIFARRARTREGRLQVELARLTYERSRLVRTWTHLERQRGGFGVMGGPGETQIETDRRL
LAEKIGKLKRELVEVRRTRTLQRSARRRVPYPTVALVGYTNAGKSTLFNRLTQAEVLAQDMLFATLDPTLRMLKLPDGRP
AILSDTVGFISDLPHELVEAFRATLEEVREADVVLHVRDIASEETEAQAQDVRTVLQRLGVDMDERRILEVWNKVDLLPA
DERQDAAGDARRAHPPAILVSAVTGEGCDDLLRAVGALVDEAPPVDVYAPAGEGAAIAWLYRHGRVVERVEGKDGSVRLA
VSLSPQALGQFEQLFPHAEVRGAG
>Mature_424_residues
MIHPDREGRTSAVRDPQARLEEAVGLAQALDLEVRETLVAPLRRLTPATLFGKGKVEEVAAVVDSVEADVVVVDDALTPV
QQRNLEKAWKAKVIDRTGLILEIFARRARTREGRLQVELARLTYERSRLVRTWTHLERQRGGFGVMGGPGETQIETDRRL
LAEKIGKLKRELVEVRRTRTLQRSARRRVPYPTVALVGYTNAGKSTLFNRLTQAEVLAQDMLFATLDPTLRMLKLPDGRP
AILSDTVGFISDLPHELVEAFRATLEEVREADVVLHVRDIASEETEAQAQDVRTVLQRLGVDMDERRILEVWNKVDLLPA
DERQDAAGDARRAHPPAILVSAVTGEGCDDLLRAVGALVDEAPPVDVYAPAGEGAAIAWLYRHGRVVERVEGKDGSVRLA
VSLSPQALGQFEQLFPHAEVRGAG

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=311, Percent_Identity=37.620578778135, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI310133116, Length=295, Percent_Identity=37.2881355932203, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI310124269, Length=276, Percent_Identity=37.6811594202899, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI310124267, Length=276, Percent_Identity=37.6811594202899, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI310124171, Length=276, Percent_Identity=37.6811594202899, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI310124169, Length=276, Percent_Identity=37.6811594202899, Blast_Score=157, Evalue=2e-38,
Organism=Escherichia coli, GI1790615, Length=386, Percent_Identity=45.3367875647668, Blast_Score=286, Evalue=1e-78,
Organism=Caenorhabditis elegans, GI17561038, Length=436, Percent_Identity=30.2752293577982, Blast_Score=181, Evalue=8e-46,
Organism=Drosophila melanogaster, GI24650079, Length=420, Percent_Identity=32.6190476190476, Blast_Score=157, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 46962; Mature: 46962

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHPDREGRTSAVRDPQARLEEAVGLAQALDLEVRETLVAPLRRLTPATLFGKGKVEEVA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHH
AVVDSVEADVVVVDDALTPVQQRNLEKAWKAKVIDRTGLILEIFARRARTREGRLQVELA
HHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEHHH
RLTYERSRLVRTWTHLERQRGGFGVMGGPGETQIETDRRLLAEKIGKLKRELVEVRRTRT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQRSARRRVPYPTVALVGYTNAGKSTLFNRLTQAEVLAQDMLFATLDPTLRMLKLPDGRP
HHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCCCC
AILSDTVGFISDLPHELVEAFRATLEEVREADVVLHVRDIASEETEAQAQDVRTVLQRLG
CHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEHHHHCCCHHHHHHHHHHHHHHHHC
VDMDERRILEVWNKVDLLPADERQDAAGDARRAHPPAILVSAVTGEGCDDLLRAVGALVD
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHC
EAPPVDVYAPAGEGAAIAWLYRHGRVVERVEGKDGSVRLAVSLSPQALGQFEQLFPHAEV
CCCCCEEECCCCCCCEEEHHHHCCCHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCCCC
RGAG
CCCC
>Mature Secondary Structure
MIHPDREGRTSAVRDPQARLEEAVGLAQALDLEVRETLVAPLRRLTPATLFGKGKVEEVA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHH
AVVDSVEADVVVVDDALTPVQQRNLEKAWKAKVIDRTGLILEIFARRARTREGRLQVELA
HHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEHHH
RLTYERSRLVRTWTHLERQRGGFGVMGGPGETQIETDRRLLAEKIGKLKRELVEVRRTRT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LQRSARRRVPYPTVALVGYTNAGKSTLFNRLTQAEVLAQDMLFATLDPTLRMLKLPDGRP
HHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEECCCCCC
AILSDTVGFISDLPHELVEAFRATLEEVREADVVLHVRDIASEETEAQAQDVRTVLQRLG
CHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEHHHHCCCHHHHHHHHHHHHHHHHC
VDMDERRILEVWNKVDLLPADERQDAAGDARRAHPPAILVSAVTGEGCDDLLRAVGALVD
CCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHC
EAPPVDVYAPAGEGAAIAWLYRHGRVVERVEGKDGSVRLAVSLSPQALGQFEQLFPHAEV
CCCCCEEECCCCCCCEEEHHHHCCCHHHHHCCCCCCEEEEEECCHHHHHHHHHHCCCCCC
RGAG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]