Click here to switch to the map view.

The map label for this gene is aroB [H]

Identifier: 197105154

GI number: 197105154

Start: 1895041

End: 1896546

Strand: Direct

Name: aroB [H]

Synonym: PHZ_c1691

Alternate gene names: 197105154

Gene position: 1895041-1896546 (Clockwise)

Preceding gene: 197105153

Following gene: 197105156

Centisome position: 47.42

GC content: 73.37

Gene sequence:

>1506_bases
ATGTGGCCCCGCGCGGATAACCACCCCGACTCCCGGCTGGCCGCCGTCATCGACGTCGGCTCGAATTCGGTCCGCCTGGT
GATCTACCGGGTGGACGGCCGCGCGCTCTGGACCGTCTACAACGAGAAGGTGGTCGCGGGCCTGGGCAAGGACCTGCCCG
TCACCGGGCGCCTGTCCGCGGAGGGAGTCGAGGCCGCGGTCGCGGCGCTGCGCCGTTTCCGCGCCGTGCTGGAAGGCTGG
CGCGCCGACCAGGTGCTGACCGCCGCCACCGCCGCTGTCCGAGAAGCCGCAGACGGCCGGGCGTTCCTGCAGCGGGTGAA
GGACGAGGCGGGCCTCGACGTACGCATCCTCTCGGGCGACGAGGAGGCCCACTACGCCGCCCTCGGCGTCACCGCCGGCG
ATCCGCTGGCGAAGGGCGTCGTGGGCGACCTCGGCGGCTCCAGCCTCGAGCTGATCCGCCTGAACGGCAAGGCCTCGGTG
GAGGGAGTCACCCTGCCGCTCGGCCCCTTCGCGCTGGGCGCGCCCAAGCCGCTGGACGTCGAGCGCATCCGCCGGGCCGT
GGACGAGCACCTGGCGCCGCTCGCCGGCCGGTTCCGGTCGCCGGAGTTCCATGCGGTCGGCGGCGCCTGGCGCAACCTCG
CCCTGCTGCACATGCAGCTCGCGGACTATCCGCTTCACGTCGCCCATCAGTACGAGATGAGCCGCGCCGACGCGATCGAC
GTCAGCCGCTTCGTCGAGCGCCAGTCGCGCACCTCGCTGGAGAAGATCCAGGGCCTCTCCAAGAAGCGCTTCGACACCCT
GCCCTACTCGGCCCTGGTGCTGGACCGCCTGATCGAGCGCCTGGGGATCGAGCGGATCGTGATCTCGGCCTATGGGGTCC
GCGAGGGGATGCTGCTGGAGGCCATGCCGCCGAAGGTGCGCGAGCGCGACCCGCTGATCGCCGGCTGCGAGGCGCTGACG
TCCCAGCGCGGCGTCGGCCCCGACCTCGGGCCGGCCATCGAGGCCTGGATCACCCCGCTGTTCGAGGGGCTGCCGCCGGT
GTTCGGCGAGCGCGAGCCGCTGCTGATCGCCGCCGCCTGCCGCCTGGCCGACCTCGGCGCCCGGCTGCACCCCGACCATC
GGGACGCCCTCGTCTTCGAGCAGGTGCTGCGCGCGCCGATCGCCGGCATGAGCCATCCCGAGCGCGCGTTCCTGGCGTGC
GTCGCCTTCTCCCGCCATTCCTCGGCCGCGGCCCCGCCGGACATGTCCGCCGTGAGCCGGCTGTTGACCCCGGACCGGCG
CCAGCGGGCGCGGGCGCTCGGCTCGGCGATCCGCCTGGCCGCCGACCTGTCGGGCCGCAATCCGGTCCTGCTGGAGAAGT
CGAGCCTGCGCCTCAACGCCGGGCGGCTGCACCTTTCGACCCTGGCGGGCTGGGAGGACATGCTGCTGGGGGAACAGACG
GCCAAGCGGGCCCAGACCCTGGCCCAGGCGCTGAAGCTCAAGCTCGAGATGGGCCGCGCCGCATAG

Upstream 100 bases:

>100_bases
GACCACCCGAACGCGTTTTCCGCGCACGAGTATTTCATGACCAATCCGAGCCTCTCGGGCCGAGGGCAGCGAGTGAAGGA
CATGCCGCGCGCGATCGATC

Downstream 100 bases:

>100_bases
CAAGAGGGCGGCGCCCCGGTTTCCCGGAACACCGCCCTCTGAACCAGATCCGTTGGGGGATCTGAGCCTTCGAGGTCGGA
AGGCATCTCCGCTCCGCCGG

Product: exopolyphosphatase

Products: NA

Alternate protein names: 3-dehydroquinate synthase; Unknown phosphatase [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MWPRADNHPDSRLAAVIDVGSNSVRLVIYRVDGRALWTVYNEKVVAGLGKDLPVTGRLSAEGVEAAVAALRRFRAVLEGW
RADQVLTAATAAVREAADGRAFLQRVKDEAGLDVRILSGDEEAHYAALGVTAGDPLAKGVVGDLGGSSLELIRLNGKASV
EGVTLPLGPFALGAPKPLDVERIRRAVDEHLAPLAGRFRSPEFHAVGGAWRNLALLHMQLADYPLHVAHQYEMSRADAID
VSRFVERQSRTSLEKIQGLSKKRFDTLPYSALVLDRLIERLGIERIVISAYGVREGMLLEAMPPKVRERDPLIAGCEALT
SQRGVGPDLGPAIEAWITPLFEGLPPVFGEREPLLIAAACRLADLGARLHPDHRDALVFEQVLRAPIAGMSHPERAFLAC
VAFSRHSSAAAPPDMSAVSRLLTPDRRQRARALGSAIRLAADLSGRNPVLLEKSSLRLNAGRLHLSTLAGWEDMLLGEQT
AKRAQTLAQALKLKLEMGRAA

Sequences:

>Translated_501_residues
MWPRADNHPDSRLAAVIDVGSNSVRLVIYRVDGRALWTVYNEKVVAGLGKDLPVTGRLSAEGVEAAVAALRRFRAVLEGW
RADQVLTAATAAVREAADGRAFLQRVKDEAGLDVRILSGDEEAHYAALGVTAGDPLAKGVVGDLGGSSLELIRLNGKASV
EGVTLPLGPFALGAPKPLDVERIRRAVDEHLAPLAGRFRSPEFHAVGGAWRNLALLHMQLADYPLHVAHQYEMSRADAID
VSRFVERQSRTSLEKIQGLSKKRFDTLPYSALVLDRLIERLGIERIVISAYGVREGMLLEAMPPKVRERDPLIAGCEALT
SQRGVGPDLGPAIEAWITPLFEGLPPVFGEREPLLIAAACRLADLGARLHPDHRDALVFEQVLRAPIAGMSHPERAFLAC
VAFSRHSSAAAPPDMSAVSRLLTPDRRQRARALGSAIRLAADLSGRNPVLLEKSSLRLNAGRLHLSTLAGWEDMLLGEQT
AKRAQTLAQALKLKLEMGRAA
>Mature_501_residues
MWPRADNHPDSRLAAVIDVGSNSVRLVIYRVDGRALWTVYNEKVVAGLGKDLPVTGRLSAEGVEAAVAALRRFRAVLEGW
RADQVLTAATAAVREAADGRAFLQRVKDEAGLDVRILSGDEEAHYAALGVTAGDPLAKGVVGDLGGSSLELIRLNGKASV
EGVTLPLGPFALGAPKPLDVERIRRAVDEHLAPLAGRFRSPEFHAVGGAWRNLALLHMQLADYPLHVAHQYEMSRADAID
VSRFVERQSRTSLEKIQGLSKKRFDTLPYSALVLDRLIERLGIERIVISAYGVREGMLLEAMPPKVRERDPLIAGCEALT
SQRGVGPDLGPAIEAWITPLFEGLPPVFGEREPLLIAAACRLADLGARLHPDHRDALVFEQVLRAPIAGMSHPERAFLAC
VAFSRHSSAAAPPDMSAVSRLLTPDRRQRARALGSAIRLAADLSGRNPVLLEKSSLRLNAGRLHLSTLAGWEDMLLGEQT
AKRAQTLAQALKLKLEMGRAA

Specific function: Degradation Of Inorganic Polyphosphates. Orthophosphate Is Released Progressively From The Ends Of Polyphosphate Of Circa 500 Residues Long, While Chains Of Circa 15 Residues Compete Poorly With Polyphosphate As Substrate. [C]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=346, Percent_Identity=25.1445086705202, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994966, Length=330, Percent_Identity=26.0606060606061, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002658
- InterPro:   IPR016037
- InterPro:   IPR003695 [H]

Pfam domain/function: PF01761 DHQ_synthase; PF02541 Ppx-GppA [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 54230; Mature: 54230

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWPRADNHPDSRLAAVIDVGSNSVRLVIYRVDGRALWTVYNEKVVAGLGKDLPVTGRLSA
CCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCEEEEEEECCHHHHHCCCCCCCCCCCCH
EGVEAAVAALRRFRAVLEGWRADQVLTAATAAVREAADGRAFLQRVKDEAGLDVRILSGD
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCC
EEAHYAALGVTAGDPLAKGVVGDLGGSSLELIRLNGKASVEGVTLPLGPFALGAPKPLDV
CCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCH
ERIRRAVDEHLAPLAGRFRSPEFHAVGGAWRNLALLHMQLADYPLHVAHQYEMSRADAID
HHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VSRFVERQSRTSLEKIQGLSKKRFDTLPYSALVLDRLIERLGIERIVISAYGVREGMLLE
HHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHCHHEEEEECCCCCCCCEEE
AMPPKVRERDPLIAGCEALTSQRGVGPDLGPAIEAWITPLFEGLPPVFGEREPLLIAAAC
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEHHHHH
RLADLGARLHPDHRDALVFEQVLRAPIAGMSHPERAFLACVAFSRHSSAAAPPDMSAVSR
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
LLTPDRRQRARALGSAIRLAADLSGRNPVLLEKSSLRLNAGRLHLSTLAGWEDMLLGEQT
HHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECCEEEEHHHCCHHHHHHCHHH
AKRAQTLAQALKLKLEMGRAA
HHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MWPRADNHPDSRLAAVIDVGSNSVRLVIYRVDGRALWTVYNEKVVAGLGKDLPVTGRLSA
CCCCCCCCCCCCEEEEEEECCCCEEEEEEEECCEEEEEEECCHHHHHCCCCCCCCCCCCH
EGVEAAVAALRRFRAVLEGWRADQVLTAATAAVREAADGRAFLQRVKDEAGLDVRILSGD
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEECCC
EEAHYAALGVTAGDPLAKGVVGDLGGSSLELIRLNGKASVEGVTLPLGPFALGAPKPLDV
CCCEEEEEEECCCCHHHHHHHHCCCCCCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCH
ERIRRAVDEHLAPLAGRFRSPEFHAVGGAWRNLALLHMQLADYPLHVAHQYEMSRADAID
HHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
VSRFVERQSRTSLEKIQGLSKKRFDTLPYSALVLDRLIERLGIERIVISAYGVREGMLLE
HHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHCHHEEEEECCCCCCCCEEE
AMPPKVRERDPLIAGCEALTSQRGVGPDLGPAIEAWITPLFEGLPPVFGEREPLLIAAAC
CCCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEHHHHH
RLADLGARLHPDHRDALVFEQVLRAPIAGMSHPERAFLACVAFSRHSSAAAPPDMSAVSR
HHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHH
LLTPDRRQRARALGSAIRLAADLSGRNPVLLEKSSLRLNAGRLHLSTLAGWEDMLLGEQT
HHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEECCEEEEHHHCCHHHHHHCHHH
AKRAQTLAQALKLKLEMGRAA
HHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11889109 [H]