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The map label for this gene is ribE [H]

Identifier: 197105133

GI number: 197105133

Start: 1874926

End: 1875516

Strand: Reverse

Name: ribE [H]

Synonym: PHZ_c1670

Alternate gene names: 197105133

Gene position: 1875516-1874926 (Counterclockwise)

Preceding gene: 197105134

Following gene: 197105132

Centisome position: 46.93

GC content: 69.71

Gene sequence:

>591_bases
ATGTTCACCGGCATCGTCACCGACGTGGGCCGCGTGCGGTCTGTGCGGGAGACCAATCGCGACCGCAGGTTCGAGATCGA
GACCGCGTTCGACACCTCCACCCTCGACATCGGCGCCTCGGTCAGCCACGCGGGCTGCTGCCTGACGATCGTGGAGAAGG
GTCCGGGCTGGTTCGCCGTCGAGGTGTCGGGCGAGACGCTGTCGCGCACCACTCTCGATCAGTGGGCCGTGGGCCGCCGG
GTGAACCTGGAGCGCGCCGCCCGGGTCGGCGACGAGCTGGGAGGCCACATCGTCTCTGGCCATGTGGACGGCGTCGGCGA
GGTGGTGAGCGTCGAGAGCGAGGGCGGCTCGCACCGCGTGCGGATCCGCGCGCCCCGGCCGTTGCACCGCTACATCGCCG
AGAAGGGCTCCATCGCCGTCGAAGGCGTGTCGCTGACGGTGAACGAGGTCGAGGACGACGTCTTCGGCGTGAACCTGATC
CCGCACACCTGGGAGGTGACCACCCTGGGCGAGCTCGCGCCGGGCGGCCGGGTCAATCTCGAGATCGACATGCTCGCGAG
GTATCTCGCCCGCTGGCGCGAAACCGCCTAA

Upstream 100 bases:

>100_bases
CGCCCTGGCCGTTGCAGCGCTTGTGGATGCGCCCCATTTCCGGCGCGTCGAGGTCCGCGAACTGGGCGACGACCTCTGGG
AACGCTACGAAAGGATCTAG

Downstream 100 bases:

>100_bases
AGGGGCGGGAATGAGCGACCAACCCCTTCGCATCCTGATCGTGGAAGCGCGCTTCTACGACGACCTGGCCGACGCCCTGC
TGGAAGGCGCCGTCGACGCG

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MFTGIVTDVGRVRSVRETNRDRRFEIETAFDTSTLDIGASVSHAGCCLTIVEKGPGWFAVEVSGETLSRTTLDQWAVGRR
VNLERAARVGDELGGHIVSGHVDGVGEVVSVESEGGSHRVRIRAPRPLHRYIAEKGSIAVEGVSLTVNEVEDDVFGVNLI
PHTWEVTTLGELAPGGRVNLEIDMLARYLARWRETA

Sequences:

>Translated_196_residues
MFTGIVTDVGRVRSVRETNRDRRFEIETAFDTSTLDIGASVSHAGCCLTIVEKGPGWFAVEVSGETLSRTTLDQWAVGRR
VNLERAARVGDELGGHIVSGHVDGVGEVVSVESEGGSHRVRIRAPRPLHRYIAEKGSIAVEGVSLTVNEVEDDVFGVNLI
PHTWEVTTLGELAPGGRVNLEIDMLARYLARWRETA
>Mature_196_residues
MFTGIVTDVGRVRSVRETNRDRRFEIETAFDTSTLDIGASVSHAGCCLTIVEKGPGWFAVEVSGETLSRTTLDQWAVGRR
VNLERAARVGDELGGHIVSGHVDGVGEVVSVESEGGSHRVRIRAPRPLHRYIAEKGSIAVEGVSLTVNEVEDDVFGVNLI
PHTWEVTTLGELAPGGRVNLEIDMLARYLARWRETA

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=185, Percent_Identity=41.0810810810811, Blast_Score=128, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6319733, Length=161, Percent_Identity=34.7826086956522, Blast_Score=95, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 21390; Mature: 21390

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGIVTDVGRVRSVRETNRDRRFEIETAFDTSTLDIGASVSHAGCCLTIVEKGPGWFAV
CCCCHHCCHHHHHHHHHCCCCCEEEEEEECCCCEEECCCCCCCCCEEEEEEECCCCEEEE
EVSGETLSRTTLDQWAVGRRVNLERAARVGDELGGHIVSGHVDGVGEVVSVESEGGSHRV
EECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCCEEEEEECCCCCEEE
RIRAPRPLHRYIAEKGSIAVEGVSLTVNEVEDDVFGVNLIPHTWEVTTLGELAPGGRVNL
EEECCCHHHHHHHCCCCEEEEEEEEEEECCCCCEEEEEECCCEEEEEECCCCCCCCEEEE
EIDMLARYLARWRETA
EHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFTGIVTDVGRVRSVRETNRDRRFEIETAFDTSTLDIGASVSHAGCCLTIVEKGPGWFAV
CCCCHHCCHHHHHHHHHCCCCCEEEEEEECCCCEEECCCCCCCCCEEEEEEECCCCEEEE
EVSGETLSRTTLDQWAVGRRVNLERAARVGDELGGHIVSGHVDGVGEVVSVESEGGSHRV
EECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCEEEECCCCCCCEEEEEECCCCCEEE
RIRAPRPLHRYIAEKGSIAVEGVSLTVNEVEDDVFGVNLIPHTWEVTTLGELAPGGRVNL
EEECCCHHHHHHHCCCCEEEEEEEEEEECCCCCEEEEEECCCEEEEEECCCCCCCCEEEE
EIDMLARYLARWRETA
EHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8144477 [H]