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The map label for this gene is engA [H]

Identifier: 197104999

GI number: 197104999

Start: 1736259

End: 1737788

Strand: Direct

Name: engA [H]

Synonym: PHZ_c1536

Alternate gene names: 197104999

Gene position: 1736259-1737788 (Clockwise)

Preceding gene: 197104998

Following gene: 197105005

Centisome position: 43.45

GC content: 71.05

Gene sequence:

>1530_bases
ATGCCGCTGAAGCTCGCGATCGTCGGCCGCCCGAATGTGGGCAAGTCCACGCTGTTCAACCGGCTGGCGGGCCGCAAGCT
CGCCATAGTCGACGACCGGCCGGGGGTCACCCGCGACCGCCGGTTCGGCACGGGCCGCCTGGGCGACCTGGATCTCGAGC
TGATCGACACCGCCGGGTTCGAGGACGTCACCGACGAGAGCCTCGAGGCCCGCATGCGCGCCCAGACCGAGCGGGCGGTG
GACGAATGCGACGTGGCGCTCTTCGTCATCGACTCCCGCGAGGGCGTCACGCCGGCGGACAGGATCTTCGCCGAAATCCT
GCGCAAGCGGGACAAGCCTGTCATCCTCGCCGCCAACAAGGCCGAGGGCAGGCAGGGCGAGGCCGGCATCCTCGACGCCT
GGGGCCTGGGCCTGGGCGAGCCGGTCCCGATCTCGGCCGAACACGGCGAGGGCATGGCCGACCTCTATGCGGCGCTGGCC
GCCGTCTGGGCCGAGGACGAGGACGAGGAGGAGGCCGAGGACGAGAGCGACAAGCCGGTCCGCATCGCCATCGTCGGCCG
CCCGAACGCGGGCAAGTCCACCCTGGTCAACCGGCTCATCGGCGAGGACCGCCTGCTGACCGGCCCGGAGGCGGGGATCA
CGCGCGACGCCATTCCCGTCGACTGGGAGTGGGAGGGACGGCCGATCCGCCTGGTCGATACGGCGGGCCTGCGGCGCAAG
GCCAAGGTGCAGGAGAAGCTGGAGAAGCTTTCCACCCAGGACACCATCCGGGCCATCACGTTCGCCGAGGTGGTGCTGCT
GGTGATGGACGCCACCCATCCGTTCGAGATCCAGGACCTGCAGATCGCCGACCTCTGCGAGCGCGAGGGGCGGGGGCTGG
TGTTCGTGCTGACCAAGTGGGACCTGGTGGAGGAGCCGCAGGCGGTCCTCGCCGAGATCACCGAGGAGGCCTACCGCCTC
CTGCCGCAGGTGAAGGGATCGCCCATCGTGGCGCTTTCGGCCGAGACCGGCCGGGGCATGGACCGGCTGATGCCGGCCGT
CCTGAAGGTCCATGGCGACTGGTCGACGAAGGTGAAGACCCGCGACCTCAACGACTGGCTGCGCATGGCCGTCGAGCGGC
ACCCGCCGCCGGCGGTGAACGGCCGGCGGGTGAAGCCGAAGTACATGGCCCAGACCAAGGCCAGGCCGCCGACGTTCGTG
ATGTTCGCCTCCCGCGCCGACCAGCTGCCGGACCACTACCGGCGCTATCTGGTCAATTCGCTGCGCGAGAGCTTCGACCT
GCCGGGGGTGCCGATCCGGCTCAGCGTGCGGTCGAACAAGAACCCCTTCGCCGAGGGGCAGGAGGGGGGCGCCGAACGCG
CGCCCGCGCCGCGCTCCAAGCCGAAGGGGGAGGGCGGTCCGCCGAAGCCGAAAGGCCCGGCCAAGGCCAAGCGCACGCCG
ACCCGGGGACGGGCGGCCAAGCTGGCCCGGCCCGGCGTCAAGCCGAAGCGAGCTTCCCGGCCCTCTTCCAGTCGGCGAAC
ACCACGTTAG

Upstream 100 bases:

>100_bases
GGCCATGCTCTCGCCCATCGCCATGGGCGACACCATCTACGTGGTCACCGACGAAGCCACGCTGATCGCACTTCGTTGAC
CGGACGTATAGGCTGACGGC

Downstream 100 bases:

>100_bases
ACGTGGGCAGGCCCAGGTCGGCCTGGGCGAGCTCCACCACCAGCGGCCCGATCTCGGAGGGGTCGGGCAGGCTCATCGGA
TCCTCGCCCGGCATGGCCTC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 509; Mature: 508

Protein sequence:

>509_residues
MPLKLAIVGRPNVGKSTLFNRLAGRKLAIVDDRPGVTRDRRFGTGRLGDLDLELIDTAGFEDVTDESLEARMRAQTERAV
DECDVALFVIDSREGVTPADRIFAEILRKRDKPVILAANKAEGRQGEAGILDAWGLGLGEPVPISAEHGEGMADLYAALA
AVWAEDEDEEEAEDESDKPVRIAIVGRPNAGKSTLVNRLIGEDRLLTGPEAGITRDAIPVDWEWEGRPIRLVDTAGLRRK
AKVQEKLEKLSTQDTIRAITFAEVVLLVMDATHPFEIQDLQIADLCEREGRGLVFVLTKWDLVEEPQAVLAEITEEAYRL
LPQVKGSPIVALSAETGRGMDRLMPAVLKVHGDWSTKVKTRDLNDWLRMAVERHPPPAVNGRRVKPKYMAQTKARPPTFV
MFASRADQLPDHYRRYLVNSLRESFDLPGVPIRLSVRSNKNPFAEGQEGGAERAPAPRSKPKGEGGPPKPKGPAKAKRTP
TRGRAAKLARPGVKPKRASRPSSSRRTPR

Sequences:

>Translated_509_residues
MPLKLAIVGRPNVGKSTLFNRLAGRKLAIVDDRPGVTRDRRFGTGRLGDLDLELIDTAGFEDVTDESLEARMRAQTERAV
DECDVALFVIDSREGVTPADRIFAEILRKRDKPVILAANKAEGRQGEAGILDAWGLGLGEPVPISAEHGEGMADLYAALA
AVWAEDEDEEEAEDESDKPVRIAIVGRPNAGKSTLVNRLIGEDRLLTGPEAGITRDAIPVDWEWEGRPIRLVDTAGLRRK
AKVQEKLEKLSTQDTIRAITFAEVVLLVMDATHPFEIQDLQIADLCEREGRGLVFVLTKWDLVEEPQAVLAEITEEAYRL
LPQVKGSPIVALSAETGRGMDRLMPAVLKVHGDWSTKVKTRDLNDWLRMAVERHPPPAVNGRRVKPKYMAQTKARPPTFV
MFASRADQLPDHYRRYLVNSLRESFDLPGVPIRLSVRSNKNPFAEGQEGGAERAPAPRSKPKGEGGPPKPKGPAKAKRTP
TRGRAAKLARPGVKPKRASRPSSSRRTPR
>Mature_508_residues
PLKLAIVGRPNVGKSTLFNRLAGRKLAIVDDRPGVTRDRRFGTGRLGDLDLELIDTAGFEDVTDESLEARMRAQTERAVD
ECDVALFVIDSREGVTPADRIFAEILRKRDKPVILAANKAEGRQGEAGILDAWGLGLGEPVPISAEHGEGMADLYAALAA
VWAEDEDEEEAEDESDKPVRIAIVGRPNAGKSTLVNRLIGEDRLLTGPEAGITRDAIPVDWEWEGRPIRLVDTAGLRRKA
KVQEKLEKLSTQDTIRAITFAEVVLLVMDATHPFEIQDLQIADLCEREGRGLVFVLTKWDLVEEPQAVLAEITEEAYRLL
PQVKGSPIVALSAETGRGMDRLMPAVLKVHGDWSTKVKTRDLNDWLRMAVERHPPPAVNGRRVKPKYMAQTKARPPTFVM
FASRADQLPDHYRRYLVNSLRESFDLPGVPIRLSVRSNKNPFAEGQEGGAERAPAPRSKPKGEGGPPKPKGPAKAKRTPT
RGRAAKLARPGVKPKRASRPSSSRRTPR

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=465, Percent_Identity=40, Blast_Score=327, Evalue=1e-90,
Organism=Escherichia coli, GI1788919, Length=150, Percent_Identity=34.6666666666667, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI2367268, Length=157, Percent_Identity=35.6687898089172, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=170, Percent_Identity=28.2352941176471, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 56138; Mature: 56007

Theoretical pI: Translated: 9.76; Mature: 9.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLKLAIVGRPNVGKSTLFNRLAGRKLAIVDDRPGVTRDRRFGTGRLGDLDLELIDTAGF
CCEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EDVTDESLEARMRAQTERAVDECDVALFVIDSREGVTPADRIFAEILRKRDKPVILAANK
CCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECC
AEGRQGEAGILDAWGLGLGEPVPISAEHGEGMADLYAALAAVWAEDEDEEEAEDESDKPV
CCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCE
RIAIVGRPNAGKSTLVNRLIGEDRLLTGPEAGITRDAIPVDWEWEGRPIRLVDTAGLRRK
EEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEECCCCCEEEEECCCCHHH
AKVQEKLEKLSTQDTIRAITFAEVVLLVMDATHPFEIQDLQIADLCEREGRGLVFVLTKW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHCCCCEEEEEECC
DLVEEPQAVLAEITEEAYRLLPQVKGSPIVALSAETGRGMDRLMPAVLKVHGDWSTKVKT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHEECCCCCCEEEC
RDLNDWLRMAVERHPPPAVNGRRVKPKYMAQTKARPPTFVMFASRADQLPDHYRRYLVNS
CCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCHHHCCHHHHHHHHHHH
LRESFDLPGVPIRLSVRSNKNPFAEGQEGGAERAPAPRSKPKGEGGPPKPKGPAKAKRTP
HHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TRGRAAKLARPGVKPKRASRPSSSRRTPR
CCCCHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PLKLAIVGRPNVGKSTLFNRLAGRKLAIVDDRPGVTRDRRFGTGRLGDLDLELIDTAGF
CEEEEEECCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCCC
EDVTDESLEARMRAQTERAVDECDVALFVIDSREGVTPADRIFAEILRKRDKPVILAANK
CCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEECC
AEGRQGEAGILDAWGLGLGEPVPISAEHGEGMADLYAALAAVWAEDEDEEEAEDESDKPV
CCCCCCCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCCE
RIAIVGRPNAGKSTLVNRLIGEDRLLTGPEAGITRDAIPVDWEWEGRPIRLVDTAGLRRK
EEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCCCCCEECCCCCEEEEECCCCHHH
AKVQEKLEKLSTQDTIRAITFAEVVLLVMDATHPFEIQDLQIADLCEREGRGLVFVLTKW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHCCCCEEEEEECC
DLVEEPQAVLAEITEEAYRLLPQVKGSPIVALSAETGRGMDRLMPAVLKVHGDWSTKVKT
CCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHEECCCCCCEEEC
RDLNDWLRMAVERHPPPAVNGRRVKPKYMAQTKARPPTFVMFASRADQLPDHYRRYLVNS
CCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCEEEEECCHHHCCHHHHHHHHHHH
LRESFDLPGVPIRLSVRSNKNPFAEGQEGGAERAPAPRSKPKGEGGPPKPKGPAKAKRTP
HHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TRGRAAKLARPGVKPKRASRPSSSRRTPR
CCCCHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA