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The map label for this gene is erg3 [H]

Identifier: 197104838

GI number: 197104838

Start: 1556117

End: 1557034

Strand: Direct

Name: erg3 [H]

Synonym: PHZ_c1372

Alternate gene names: 197104838

Gene position: 1556117-1557034 (Clockwise)

Preceding gene: 197104837

Following gene: 197104841

Centisome position: 38.94

GC content: 67.43

Gene sequence:

>918_bases
ATGAAGACCTTCGACCCGGTCACGTTGGCCACGCCCTTCTTCATCCTGACCATCATCCTCGAAATCGTCCTGACCCGGTT
CGGCAAGCTGCGGGCGAACTACGAGGCGAAGGACACGGCGGTGTCGCTCGGCATGGGCCTGGGCTCGACCGTGGCCGGCG
TGCTGTTCGGCGGGATGATCGCGGCCGCGACGCTGTGGGTGCATCAGTTCCGGCTGTTCGACATCCCAATGACGGCCGTG
TGGGCCTGGGTGGCGATCTTCCTGCTGGAGGACCTGACCTACTACTGGTTCCACCGCCTGGCGCACGAGCGGCGGTTCTG
GTGGGCGAGCCACGTCAACCACCACTCCAGCCAGCACTACAACCTCTCGACGGCGCTGCGGCAGACCTGGACGGGCGGAA
TCGCCGGCACCTGGCTGCTCTGGCTGCCCCTGTCGTTCCTGGGCTTCCCGCCGGCGATGATCGCCATCCAGAAGGGGATC
AGCCTCGTCTACCAGTACTGGATCCACACCGAGGCGATCCGGCGGATGCCGCGCTGGTTCGAGGCGGTCTTCAACACCCC
TTCGCACCATCGGGTGCACCATGCCCGCAACCCGCGCTACCTCGACCGTAACTACGCGGGGATCCTGATCATCTGGGACC
GCCTCTTCGGCACCTTCCAGCCCGAGCTGGACGAGGAGCCGTGCCGCTACGGGATCGTGAAGAACCTCGGCACCTTCAAC
ATCGTCCGCGTCGCCTTCCACGAGTGGATTGCCATGCTGCAGGACGTGGCCCGCCAGCCGCGGCATGCTCTCGGCTGGTT
GTTCGGCCCGCCCGGCTGGAGCCCGGACGGCAGCCGGCAGACCAGCGCGCAGCTGAAGGCCGATTGGCACGCCCGGGCCG
CGTCCAGCGAACCGCCCGAGCTGGACCGCGCGGCCTAG

Upstream 100 bases:

>100_bases
CCAGCTTCCGGGACGGGCGGCTGTCCGTGGACCTCGCCGACGTGGCCGCCCCGCGGGCGGTCATCGCCCTGCCGGCCTGG
CCGCCCAAGGAGCTGGCGGC

Downstream 100 bases:

>100_bases
TCCCGCAGCAGCGGCAGGCTGAGCCCCGAGACCGGCCGGGCGTCCAGCACCTCTCGGCGGAAGCGGAACAACTCGGCGGG
TCGGCCGCCGGTCTCCACGT

Product: sterol desaturase

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MKTFDPVTLATPFFILTIILEIVLTRFGKLRANYEAKDTAVSLGMGLGSTVAGVLFGGMIAAATLWVHQFRLFDIPMTAV
WAWVAIFLLEDLTYYWFHRLAHERRFWWASHVNHHSSQHYNLSTALRQTWTGGIAGTWLLWLPLSFLGFPPAMIAIQKGI
SLVYQYWIHTEAIRRMPRWFEAVFNTPSHHRVHHARNPRYLDRNYAGILIIWDRLFGTFQPELDEEPCRYGIVKNLGTFN
IVRVAFHEWIAMLQDVARQPRHALGWLFGPPGWSPDGSRQTSAQLKADWHARAASSEPPELDRAA

Sequences:

>Translated_305_residues
MKTFDPVTLATPFFILTIILEIVLTRFGKLRANYEAKDTAVSLGMGLGSTVAGVLFGGMIAAATLWVHQFRLFDIPMTAV
WAWVAIFLLEDLTYYWFHRLAHERRFWWASHVNHHSSQHYNLSTALRQTWTGGIAGTWLLWLPLSFLGFPPAMIAIQKGI
SLVYQYWIHTEAIRRMPRWFEAVFNTPSHHRVHHARNPRYLDRNYAGILIIWDRLFGTFQPELDEEPCRYGIVKNLGTFN
IVRVAFHEWIAMLQDVARQPRHALGWLFGPPGWSPDGSRQTSAQLKADWHARAASSEPPELDRAA
>Mature_305_residues
MKTFDPVTLATPFFILTIILEIVLTRFGKLRANYEAKDTAVSLGMGLGSTVAGVLFGGMIAAATLWVHQFRLFDIPMTAV
WAWVAIFLLEDLTYYWFHRLAHERRFWWASHVNHHSSQHYNLSTALRQTWTGGIAGTWLLWLPLSFLGFPPAMIAIQKGI
SLVYQYWIHTEAIRRMPRWFEAVFNTPSHHRVHHARNPRYLDRNYAGILIIWDRLFGTFQPELDEEPCRYGIVKNLGTFN
IVRVAFHEWIAMLQDVARQPRHALGWLFGPPGWSPDGSRQTSAQLKADWHARAASSEPPELDRAA

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=278, Percent_Identity=39.9280575539568, Blast_Score=204, Evalue=1e-52,
Organism=Caenorhabditis elegans, GI25144659, Length=255, Percent_Identity=36.4705882352941, Blast_Score=161, Evalue=5e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 35120; Mature: 35120

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTFDPVTLATPFFILTIILEIVLTRFGKLRANYEAKDTAVSLGMGLGSTVAGVLFGGMI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
AAATLWVHQFRLFDIPMTAVWAWVAIFLLEDLTYYWFHRLAHERRFWWASHVNHHSSQHY
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NLSTALRQTWTGGIAGTWLLWLPLSFLGFPPAMIAIQKGISLVYQYWIHTEAIRRMPRWF
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVFNTPSHHRVHHARNPRYLDRNYAGILIIWDRLFGTFQPELDEEPCRYGIVKNLGTFN
HHHHCCCCCCHHHCCCCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCHHHHHHHHCCCCHH
IVRVAFHEWIAMLQDVARQPRHALGWLFGPPGWSPDGSRQTSAQLKADWHARAASSEPPE
HHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
LDRAA
CCCCC
>Mature Secondary Structure
MKTFDPVTLATPFFILTIILEIVLTRFGKLRANYEAKDTAVSLGMGLGSTVAGVLFGGMI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHH
AAATLWVHQFRLFDIPMTAVWAWVAIFLLEDLTYYWFHRLAHERRFWWASHVNHHSSQHY
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NLSTALRQTWTGGIAGTWLLWLPLSFLGFPPAMIAIQKGISLVYQYWIHTEAIRRMPRWF
HHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVFNTPSHHRVHHARNPRYLDRNYAGILIIWDRLFGTFQPELDEEPCRYGIVKNLGTFN
HHHHCCCCCCHHHCCCCCCCCCCCCCEEEEEHHHHHCCCCCCCCCCHHHHHHHHCCCCHH
IVRVAFHEWIAMLQDVARQPRHALGWLFGPPGWSPDGSRQTSAQLKADWHARAASSEPPE
HHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
LDRAA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]