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The map label for this gene is fabH [H]

Identifier: 197104835

GI number: 197104835

Start: 1553781

End: 1554893

Strand: Reverse

Name: fabH [H]

Synonym: PHZ_c1369

Alternate gene names: 197104835

Gene position: 1554893-1553781 (Counterclockwise)

Preceding gene: 197104839

Following gene: 197104834

Centisome position: 38.91

GC content: 66.49

Gene sequence:

>1113_bases
ATGAACGACGCCGTGATCGCCGCCACGGGGCTCTACACGCCGCCGCTCAGCCTCTCGAACGCCGAGCTGGTGGAAACCTT
CAACGCCTACGTGGAGCGCTTCAACGCGGCCAACGCCGAGGCCATCGCGCGCGGCGAGGTTCAGCCGCTGCAGCCGTCCT
CGGTGGAGTTCATCGAGAAGGCCTCGGGCATCAAGTCGCGCTTCGTCGTCGACAAGACCGGCCTGGTCGATCCCGAGATC
ATGCGCCCGATCATCCCCGAGCGCCCCAACGACCAGCTCTCGATCCTGGCCGAGATCGCCGTCGAGGCGGCGAAGGACGC
CATCGCCCGCTGGGGTAAGCCGGTGTCCGAGATCGACGCGGTGATCTGCGCCGCCTCGAACATGCAGCGCGCCTATCCCG
CCATGGCCATCGAAGTGCAGCAGGCCCTGGGGATCGACGGCTTCGCCTTCGACATGAACGTGGCCTGCTCCTCGGCGACC
TTCGGCATCAAGACGGCGGCCGATTTCGTGGCGGGCGGGGCGAAGGCCGTGCTGATGGTCAACCCCGAGATCTGCTCGGG
CCACCTCAACTTCCGCGACCGGGACAGCCACTTCATCTTCGGCGACGTGGCGACCGCCGTGATCGTCGAGCGCGCCGACC
AGGCGACGGACGGATGGGACATCCTCGGCACGCGGCTGAAGACCCAGTTCTCCAACAACATCCGCAACAACTTCGGCTTC
CTGAACCGGGCCGACCCGGAGGGCGTCGGCAAGCCCGACAAGCTGTTCGTCCAGGAGGGCCGCAAGGTCTTCCGCGAGGT
GGTGCCGATGGTCTCGGAGATGATCGTCGACCACGCCGCCGATCTGGGCATCGACCCCACGGGCCTGAAGCGCCTGTGGC
TGCACCAGGCCAACATCAACATGAACGAGATGATCGGCCGCAAGGTGCTGGGCCGCGATCCGGCGCCCGGCGAGAACGTA
ATCATCCTGGACGAGTACGCCAACACCTCGTCGGCCGGCTCGATCATCGCCTTCCACAAGGCCAACGACGACTTCCAGAC
GGGCGATACCGGCCTGATCTGCTCGTTCGGCGCCGGCTATTCCGCAGGCACGGTGTTCGTCCGCAAGCGGTGA

Upstream 100 bases:

>100_bases
GTTCGCCCCTGACGTGTGTCCCTGCGGCCACAATGCCCGCTGACGGGCGTGCCGCGCGTGCTACAAGCACGCGGTCCATG
AGTCCGGGAGAGCAGCCGAA

Downstream 100 bases:

>100_bases
GGCTAGGCTCTCCCGGGTCACGGGGGAGTTCTTCATGCGCAGACTGTTCGCCGCCACGGCCCTGGCGCTCGCGTTCGTGA
CGACCGGGGCGGCCGCCCCG

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MNDAVIAATGLYTPPLSLSNAELVETFNAYVERFNAANAEAIARGEVQPLQPSSVEFIEKASGIKSRFVVDKTGLVDPEI
MRPIIPERPNDQLSILAEIAVEAAKDAIARWGKPVSEIDAVICAASNMQRAYPAMAIEVQQALGIDGFAFDMNVACSSAT
FGIKTAADFVAGGAKAVLMVNPEICSGHLNFRDRDSHFIFGDVATAVIVERADQATDGWDILGTRLKTQFSNNIRNNFGF
LNRADPEGVGKPDKLFVQEGRKVFREVVPMVSEMIVDHAADLGIDPTGLKRLWLHQANINMNEMIGRKVLGRDPAPGENV
IILDEYANTSSAGSIIAFHKANDDFQTGDTGLICSFGAGYSAGTVFVRKR

Sequences:

>Translated_370_residues
MNDAVIAATGLYTPPLSLSNAELVETFNAYVERFNAANAEAIARGEVQPLQPSSVEFIEKASGIKSRFVVDKTGLVDPEI
MRPIIPERPNDQLSILAEIAVEAAKDAIARWGKPVSEIDAVICAASNMQRAYPAMAIEVQQALGIDGFAFDMNVACSSAT
FGIKTAADFVAGGAKAVLMVNPEICSGHLNFRDRDSHFIFGDVATAVIVERADQATDGWDILGTRLKTQFSNNIRNNFGF
LNRADPEGVGKPDKLFVQEGRKVFREVVPMVSEMIVDHAADLGIDPTGLKRLWLHQANINMNEMIGRKVLGRDPAPGENV
IILDEYANTSSAGSIIAFHKANDDFQTGDTGLICSFGAGYSAGTVFVRKR
>Mature_370_residues
MNDAVIAATGLYTPPLSLSNAELVETFNAYVERFNAANAEAIARGEVQPLQPSSVEFIEKASGIKSRFVVDKTGLVDPEI
MRPIIPERPNDQLSILAEIAVEAAKDAIARWGKPVSEIDAVICAASNMQRAYPAMAIEVQQALGIDGFAFDMNVACSSAT
FGIKTAADFVAGGAKAVLMVNPEICSGHLNFRDRDSHFIFGDVATAVIVERADQATDGWDILGTRLKTQFSNNIRNNFGF
LNRADPEGVGKPDKLFVQEGRKVFREVVPMVSEMIVDHAADLGIDPTGLKRLWLHQANINMNEMIGRKVLGRDPAPGENV
IILDEYANTSSAGSIIAFHKANDDFQTGDTGLICSFGAGYSAGTVFVRKR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=332, Percent_Identity=27.4096385542169, Blast_Score=98, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 39966; Mature: 39966

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDAVIAATGLYTPPLSLSNAELVETFNAYVERFNAANAEAIARGEVQPLQPSSVEFIEK
CCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHH
ASGIKSRFVVDKTGLVDPEIMRPIIPERPNDQLSILAEIAVEAAKDAIARWGKPVSEIDA
HCCCCCEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VICAASNMQRAYPAMAIEVQQALGIDGFAFDMNVACSSATFGIKTAADFVAGGAKAVLMV
HHHHHHCHHHHCCHHHEEHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCEEEEEE
NPEICSGHLNFRDRDSHFIFGDVATAVIVERADQATDGWDILGTRLKTQFSNNIRNNFGF
CHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
LNRADPEGVGKPDKLFVQEGRKVFREVVPMVSEMIVDHAADLGIDPTGLKRLWLHQANIN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEEECCCC
MNEMIGRKVLGRDPAPGENVIILDEYANTSSAGSIIAFHKANDDFQTGDTGLICSFGAGY
HHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCC
SAGTVFVRKR
CCCEEEEEEC
>Mature Secondary Structure
MNDAVIAATGLYTPPLSLSNAELVETFNAYVERFNAANAEAIARGEVQPLQPSSVEFIEK
CCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHH
ASGIKSRFVVDKTGLVDPEIMRPIIPERPNDQLSILAEIAVEAAKDAIARWGKPVSEIDA
HCCCCCEEEEECCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
VICAASNMQRAYPAMAIEVQQALGIDGFAFDMNVACSSATFGIKTAADFVAGGAKAVLMV
HHHHHHCHHHHCCHHHEEHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHCCCCEEEEEE
NPEICSGHLNFRDRDSHFIFGDVATAVIVERADQATDGWDILGTRLKTQFSNNIRNNFGF
CHHHHCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
LNRADPEGVGKPDKLFVQEGRKVFREVVPMVSEMIVDHAADLGIDPTGLKRLWLHQANIN
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHEEEECCCC
MNEMIGRKVLGRDPAPGENVIILDEYANTSSAGSIIAFHKANDDFQTGDTGLICSFGAGY
HHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCCCCEEEECCCCC
SAGTVFVRKR
CCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA