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The map label for this gene is ectB [H]

Identifier: 197104802

GI number: 197104802

Start: 1514336

End: 1515646

Strand: Direct

Name: ectB [H]

Synonym: PHZ_c1336

Alternate gene names: 197104802

Gene position: 1514336-1515646 (Clockwise)

Preceding gene: 197104801

Following gene: 197104803

Centisome position: 37.89

GC content: 71.55

Gene sequence:

>1311_bases
ATGTACGACGCCGAAGCCCCGGCGCGCGCTGACACCGCGTTCGCGCCTTTCGACCGCCTGGAGTCCCGGGTTCGTTCCTA
CTGCCGCAGCTTCCCGGCCGTGTTCGTCCGCGGGTCGGGCGCCTGGCTCTACGACGCAGACGGCAAGGCCTACCTCGACT
TCCTCAGCGGCTGCGCCAGCCTCAACTACGGCCACAACCACCCGGCCCTGAAGCAGCGGCTCGTGGAGTACATCGCCGAC
GACGGCGTGGCTCACAGCCTCGACATGCACAGCCGCGCCAAGGCCGAGTTCCTGGAGGCTTTCGAAGCGGCCATCCTGCG
GCCGCGCGGGATGTTCTACCGCGCCCAGTTCACCGGCCCCACGGGCGCCAACGCCGTCGAGGCGGCGCTGAAGCTCGCGC
GCAAGATCACCGGCCGGACGAACGTCATCGCCTTCACCAACGGCTTCCACGGCGTGACCCTGGGGGCCCTGGCTGCCACC
GGCAGCGGCGGCCACCGCGCGTCCGGCGGACTGCCCGCCCAGGGCGTCAGCCGCGCGGCCTACGACGGTTACTACGGGCC
CGACGTCGACACCGCGGCCCAGCTCGACAAGCTGCTGTCGGATCCCTCGGGCGGCATCGATCCGCCGGCCGCGATCCTCG
TGGAGACGGTGCAGGGCGAGGGCGGCCTCAACGTCGCCTCGGCCGAGTGGCTGCGCGCCATCGAGGCGATCGCGCGCAAG
CACGGGGCGCTGTTCATCATCGACGACATCCAGGCTGGCTGCGGCCGCGCCGGCGGCTTCTTCAGCTTCGAGGACATGGG
CGTGACGCCGGACATCGTCACCATGGCGAAGTCGCTCTCGGGGCTGGGCCTGCCGATGGCGCTGACGCTGATCCGTCCCG
AGCGGGACGTCTGGCATCCCGGCCAGCACAACGGCACCTTCCGCGGCAACTGCCACGCCTTCGTCACCGCCAAGGCGGCG
ATTGACACCTTCTGGCGCGACGACGCCTTCGCCGAGCGGACCGCCGCCAAGGGCGAGCGGCTGCGCGCGCGGCTCGAGGA
GATCGCCGGCAAGCATCCGGACGTCGTCCGCGGGACCAAGGGCCGCGGCATGATGCGGGGCATCGACGTCGGGTCGGGCG
AGGTCTCGGGCCGGATCGTCAAGGCGGCCTTCGAGCGCGGCCTGGTGATCGAGACCAGCGGCCCGCGCGACGAGATCGTG
AAGGTCCTGGCGCCCCTCACCATCGCCGACGAGGACCTGGACCGTGGCCTGGACATCCTGTCCGCCGCGATCGCCGACAT
CCGCGGCCGCGTGCAGCTGAACGCCGCCTGA

Upstream 100 bases:

>100_bases
CGTCCACCTGCCGGCCGGTCATTCGACCGAGCACATGGTCGCCATCGGACCATTCGACCCCGCGGCGACGCGGGCCTGAT
CCCAACCACAAGGAGACGCC

Downstream 100 bases:

>100_bases
GCCGCCGAAGACACGAGAGAGAGATACATGATCGTTCGCGACCTGAGCCAAGCCGAGAAGACCGACCGCCGCGTGGTGTC
CAAGGGGTGGGAGAGCACGC

Product: diaminobutyrate--2-oxoglutarate aminotransferase

Products: NA

Alternate protein names: DABA aminotransferase; Diaminobutyrate--2-oxoglutarate aminotransferase; L-2,4-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MYDAEAPARADTAFAPFDRLESRVRSYCRSFPAVFVRGSGAWLYDADGKAYLDFLSGCASLNYGHNHPALKQRLVEYIAD
DGVAHSLDMHSRAKAEFLEAFEAAILRPRGMFYRAQFTGPTGANAVEAALKLARKITGRTNVIAFTNGFHGVTLGALAAT
GSGGHRASGGLPAQGVSRAAYDGYYGPDVDTAAQLDKLLSDPSGGIDPPAAILVETVQGEGGLNVASAEWLRAIEAIARK
HGALFIIDDIQAGCGRAGGFFSFEDMGVTPDIVTMAKSLSGLGLPMALTLIRPERDVWHPGQHNGTFRGNCHAFVTAKAA
IDTFWRDDAFAERTAAKGERLRARLEEIAGKHPDVVRGTKGRGMMRGIDVGSGEVSGRIVKAAFERGLVIETSGPRDEIV
KVLAPLTIADEDLDRGLDILSAAIADIRGRVQLNAA

Sequences:

>Translated_436_residues
MYDAEAPARADTAFAPFDRLESRVRSYCRSFPAVFVRGSGAWLYDADGKAYLDFLSGCASLNYGHNHPALKQRLVEYIAD
DGVAHSLDMHSRAKAEFLEAFEAAILRPRGMFYRAQFTGPTGANAVEAALKLARKITGRTNVIAFTNGFHGVTLGALAAT
GSGGHRASGGLPAQGVSRAAYDGYYGPDVDTAAQLDKLLSDPSGGIDPPAAILVETVQGEGGLNVASAEWLRAIEAIARK
HGALFIIDDIQAGCGRAGGFFSFEDMGVTPDIVTMAKSLSGLGLPMALTLIRPERDVWHPGQHNGTFRGNCHAFVTAKAA
IDTFWRDDAFAERTAAKGERLRARLEEIAGKHPDVVRGTKGRGMMRGIDVGSGEVSGRIVKAAFERGLVIETSGPRDEIV
KVLAPLTIADEDLDRGLDILSAAIADIRGRVQLNAA
>Mature_436_residues
MYDAEAPARADTAFAPFDRLESRVRSYCRSFPAVFVRGSGAWLYDADGKAYLDFLSGCASLNYGHNHPALKQRLVEYIAD
DGVAHSLDMHSRAKAEFLEAFEAAILRPRGMFYRAQFTGPTGANAVEAALKLARKITGRTNVIAFTNGFHGVTLGALAAT
GSGGHRASGGLPAQGVSRAAYDGYYGPDVDTAAQLDKLLSDPSGGIDPPAAILVETVQGEGGLNVASAEWLRAIEAIARK
HGALFIIDDIQAGCGRAGGFFSFEDMGVTPDIVTMAKSLSGLGLPMALTLIRPERDVWHPGQHNGTFRGNCHAFVTAKAA
IDTFWRDDAFAERTAAKGERLRARLEEIAGKHPDVVRGTKGRGMMRGIDVGSGEVSGRIVKAAFERGLVIETSGPRDEIV
KVLAPLTIADEDLDRGLDILSAAIADIRGRVQLNAA

Specific function: Catalyzes reversively the conversion of L-aspartate beta-semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate [H]

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=416, Percent_Identity=28.125, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI13994255, Length=452, Percent_Identity=24.3362831858407, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI188536080, Length=436, Percent_Identity=23.8532110091743, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38679950, Length=436, Percent_Identity=23.8532110091743, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38679946, Length=436, Percent_Identity=23.8532110091743, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI37574042, Length=438, Percent_Identity=26.2557077625571, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI24119277, Length=439, Percent_Identity=24.8291571753986, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI226442705, Length=433, Percent_Identity=25.8660508083141, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI284507298, Length=324, Percent_Identity=27.7777777777778, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI226442709, Length=398, Percent_Identity=26.1306532663317, Blast_Score=87, Evalue=3e-17,
Organism=Escherichia coli, GI1789016, Length=397, Percent_Identity=33.5012594458438, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI1787560, Length=404, Percent_Identity=33.4158415841584, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789759, Length=411, Percent_Identity=29.9270072992701, Blast_Score=155, Evalue=6e-39,
Organism=Escherichia coli, GI145693181, Length=403, Percent_Identity=27.7915632754342, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788044, Length=423, Percent_Identity=29.5508274231678, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1786991, Length=412, Percent_Identity=25.9708737864078, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI1786349, Length=315, Percent_Identity=28.2539682539683, Blast_Score=89, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI25144271, Length=430, Percent_Identity=26.9767441860465, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI32564660, Length=432, Percent_Identity=27.5462962962963, Blast_Score=141, Evalue=9e-34,
Organism=Caenorhabditis elegans, GI17541228, Length=438, Percent_Identity=23.972602739726, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI25144274, Length=218, Percent_Identity=27.9816513761468, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71992977, Length=436, Percent_Identity=24.5412844036697, Blast_Score=99, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323470, Length=415, Percent_Identity=30.8433734939759, Blast_Score=169, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6324432, Length=415, Percent_Identity=31.0843373493976, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6321456, Length=389, Percent_Identity=25.4498714652956, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6324386, Length=435, Percent_Identity=21.8390804597701, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21357415, Length=407, Percent_Identity=26.5356265356265, Blast_Score=138, Evalue=9e-33,
Organism=Drosophila melanogaster, GI28574759, Length=439, Percent_Identity=26.1958997722096, Blast_Score=124, Evalue=2e-28,
Organism=Drosophila melanogaster, GI161085790, Length=437, Percent_Identity=26.3157894736842, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI281366494, Length=404, Percent_Identity=24.7524752475248, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24667139, Length=404, Percent_Identity=24.7524752475248, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24667143, Length=404, Percent_Identity=24.7524752475248, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI21356575, Length=426, Percent_Identity=23.0046948356808, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR012773
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 46427; Mature: 46427

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDAEAPARADTAFAPFDRLESRVRSYCRSFPAVFVRGSGAWLYDADGKAYLDFLSGCAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCHHHHHHHHHHHH
LNYGHNHPALKQRLVEYIADDGVAHSLDMHSRAKAEFLEAFEAAILRPRGMFYRAQFTGP
CCCCCCCHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
TGANAVEAALKLARKITGRTNVIAFTNGFHGVTLGALAATGSGGHRASGGLPAQGVSRAA
CCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHEECCCCCCCCCCCCCCHHCCHHH
YDGYYGPDVDTAAQLDKLLSDPSGGIDPPAAILVETVQGEGGLNVASAEWLRAIEAIARK
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHEEEEECCCCCCCCHHHHHHHHHHHHHHH
HGALFIIDDIQAGCGRAGGFFSFEDMGVTPDIVTMAKSLSGLGLPMALTLIRPERDVWHP
CCCEEEEECCCCCCCCCCCCCEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
GQHNGTFRGNCHAFVTAKAAIDTFWRDDAFAERTAAKGERLRARLEEIAGKHPDVVRGTK
CCCCCCCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GRGMMRGIDVGSGEVSGRIVKAAFERGLVIETSGPRDEIVKVLAPLTIADEDLDRGLDIL
CCCCEEEECCCCCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHH
SAAIADIRGRVQLNAA
HHHHHHHCCCEEEECC
>Mature Secondary Structure
MYDAEAPARADTAFAPFDRLESRVRSYCRSFPAVFVRGSGAWLYDADGKAYLDFLSGCAS
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCHHHHHHHHHHHH
LNYGHNHPALKQRLVEYIADDGVAHSLDMHSRAKAEFLEAFEAAILRPRGMFYRAQFTGP
CCCCCCCHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCC
TGANAVEAALKLARKITGRTNVIAFTNGFHGVTLGALAATGSGGHRASGGLPAQGVSRAA
CCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHEECCCCCCCCCCCCCCHHCCHHH
YDGYYGPDVDTAAQLDKLLSDPSGGIDPPAAILVETVQGEGGLNVASAEWLRAIEAIARK
CCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHEEEEECCCCCCCCHHHHHHHHHHHHHHH
HGALFIIDDIQAGCGRAGGFFSFEDMGVTPDIVTMAKSLSGLGLPMALTLIRPERDVWHP
CCCEEEEECCCCCCCCCCCCCEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCCC
GQHNGTFRGNCHAFVTAKAAIDTFWRDDAFAERTAAKGERLRARLEEIAGKHPDVVRGTK
CCCCCCCCCCCEEEEEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GRGMMRGIDVGSGEVSGRIVKAAFERGLVIETSGPRDEIVKVLAPLTIADEDLDRGLDIL
CCCCEEEECCCCCCCCHHHHHHHHHCCEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHH
SAAIADIRGRVQLNAA
HHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]