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The map label for this gene is hit [H]

Identifier: 197104767

GI number: 197104767

Start: 1479699

End: 1480133

Strand: Direct

Name: hit [H]

Synonym: PHZ_c1301

Alternate gene names: 197104767

Gene position: 1479699-1480133 (Clockwise)

Preceding gene: 197104766

Following gene: 197104772

Centisome position: 37.03

GC content: 67.82

Gene sequence:

>435_bases
ATGCTGGACGGCGCCTACGACCCCGACAACATCTTCGCGAAGATCCTGCGCGGCGAGATGGCCTGCGCCCGGGTGTTCGA
GGACGAGCACGTCTTCTCGTTCATGGATGTCTTCCCGCAGTCCAGGGGGCACACGCTGGTGATCCCCAAGCACACGACGG
CGCGCAATCTGCTGGAGGAGGAGCCCGAACGCCTCTCCCACCTGATCCTGGGCGTCCAGCGGGTGGCCAAGGCGGTGCGG
GCCGCGCTGAACCCCGACGGCCTGGTGATCACCCAGTTCAACGGCGCGCCGGCGGGCCAGACGATCTACCACCTGCACGT
CCACATCATCCCGCGCTGGGAAGGCGTGCCGGTGGGCCGCCACGCCTCGGGCGGCATGGCCGACATGGATGAGCTGAAGG
CGCTGGCCGAGCAGATCTCGGCGAAGATCAGCTGA

Upstream 100 bases:

>100_bases
CGGGCGTGGAGGAGGAGATCGAATGGCTCGCCGAGGAGTTCTCGCCGTTCCGGCAGGGCGGCTGATTTGCTACGAGCGCT
GGGTTGATCAGGAGTGACCC

Downstream 100 bases:

>100_bases
CGCGACAAGGCCCCGGAGATCGCTCTCTGCGATCGCTCTCCGGGGCCCTTCGCTTTTCCTCGTAGACCGCCGCTCAGTCG
ACCGGCTCGGTCTCCTCGGC

Product: diadenosine tetraphosphate (Ap4A) hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 144; Mature: 144

Protein sequence:

>144_residues
MLDGAYDPDNIFAKILRGEMACARVFEDEHVFSFMDVFPQSRGHTLVIPKHTTARNLLEEEPERLSHLILGVQRVAKAVR
AALNPDGLVITQFNGAPAGQTIYHLHVHIIPRWEGVPVGRHASGGMADMDELKALAEQISAKIS

Sequences:

>Translated_144_residues
MLDGAYDPDNIFAKILRGEMACARVFEDEHVFSFMDVFPQSRGHTLVIPKHTTARNLLEEEPERLSHLILGVQRVAKAVR
AALNPDGLVITQFNGAPAGQTIYHLHVHIIPRWEGVPVGRHASGGMADMDELKALAEQISAKIS
>Mature_144_residues
MLDGAYDPDNIFAKILRGEMACARVFEDEHVFSFMDVFPQSRGHTLVIPKHTTARNLLEEEPERLSHLILGVQRVAKAVR
AALNPDGLVITQFNGAPAGQTIYHLHVHIIPRWEGVPVGRHASGGMADMDELKALAEQISAKIS

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=105, Percent_Identity=36.1904761904762, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17506713, Length=104, Percent_Identity=32.6923076923077, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320078, Length=140, Percent_Identity=30.7142857142857, Blast_Score=69, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581222, Length=108, Percent_Identity=39.8148148148148, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI28574010, Length=108, Percent_Identity=39.8148148148148, Blast_Score=72, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: NA

Molecular weight: Translated: 15888; Mature: 15888

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDGAYDPDNIFAKILRGEMACARVFEDEHVFSFMDVFPQSRGHTLVIPKHTTARNLLEE
CCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHH
EPERLSHLILGVQRVAKAVRAALNPDGLVITQFNGAPAGQTIYHLHVHIIPRWEGVPVGR
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCC
HASGGMADMDELKALAEQISAKIS
CCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLDGAYDPDNIFAKILRGEMACARVFEDEHVFSFMDVFPQSRGHTLVIPKHTTARNLLEE
CCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHH
EPERLSHLILGVQRVAKAVRAALNPDGLVITQFNGAPAGQTIYHLHVHIIPRWEGVPVGR
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEEEEEEEEECCCCCCCCC
HASGGMADMDELKALAEQISAKIS
CCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]