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The map label for this gene is rpoB [H]

Identifier: 197104684

GI number: 197104684

Start: 1400555

End: 1404625

Strand: Direct

Name: rpoB [H]

Synonym: PHZ_c1218

Alternate gene names: 197104684

Gene position: 1400555-1404625 (Clockwise)

Preceding gene: 197104683

Following gene: 197104685

Centisome position: 35.05

GC content: 67.28

Gene sequence:

>4071_bases
ATGGCGCAGTCCTTCACCGGTAAGAAGCGGATCCGGAAGTCTTTCGGCCGCATCCCTGAAGCCGTGCAGATGCCGAACCT
GATCGAGGTTCAGCGCTCGTCCTACGAACAGTTCCTGCAGCGCGAGGTCCGCGCCGGCGAACGTCGCGACGAGGGCATCG
AGGCGGTGTTCAAGTCCGTCTTCCCGATCAAGGACTTCAACGAGCGCGCGGTGCTCGAATACGTCTCCTACGAGTTCGAG
GAGCCGAAGTACGACGTCGAGGAATGCGTCCAGCGCGACATGACCTACGCCGCGCCGCTGAAGGTCAAGCTGCGCCTGAT
CGTCTTCGAGACCGACGAGGAGACCGGCGCCCGCTCCGTCAAGGACATCAAGGAGCAGGACGTCTACATGGGCGACATCC
CGCTCATGACGGAGAAGGGCACCTTCATCGTCAACGGGACCCAGCGCGTCATCGTCTCGCAGATGCACCGCTCGCCGGGC
GTCTTCTTCGACCACGACAAGGGCAAGACCCACGCCTCGGGCAAGCTGCTGTTCGCCGCGCGCGTGATCCCCTACCGCGG
CTCGTGGCTCGACTTCGAGTTCGACGCCAAGGACATCGTCTACGTCCGTATCGACCGCCGCCGGAAGCTGCCGGCCACCA
CCTTCCTGATGGCCCTCGGCATGGACGGGGAGGAGATCCTCTCCACGTTCTACGAGACCGTGCCCTACGAGAAGAAGGGC
GACGGCTGGGCCACCCCGTACAAGCCCGAGCGCTGGCGCGGCGTGAAGCCGGAGTTCCCGCTGATCGACGCCGACACCGG
CGAGGAGATCGCTCCGGCCGGCCAGAAGATCTCGGCCCGCAACGCCAAGAAGTTCGCCGACAACGGCCTGAAGACGCTGC
TGCTGGCGCCCGAGGCGCTGACCGGCCGCTACCTGGCCAAGGACCTGGTCAACTTCGAGACTGGGGAGATCTACGCCGAG
GCCGGCGACGAGCTCGACCCGACGCTCCTGGCCGCGCTCGAGGAGCAGGGCTTCACCACCCTCGACGTCCTCGACATCGA
CGAGGTCACCGTCGGCGCCTACATCCGCAACACCCTGCGGGTGGACAAGAACACCGCGCGCGAGGACGCGCTCTTCGACA
TCTACCGGGTCATGCGCCCGGGCGAGCCGCCGACGGTCGAGGCCGCCGAGGCGATGTTCAAGAGCCTGTTCTTCGATTCC
GAGCGCTACGACCTGTCGTCGGTCGGCCGCGTGAAGATGAACATGCGCCTCGAGCTGGACTGCCCGGACGACGTCCGGGT
GATCCGCAAGGAGGACGTGATCGCCGTCCTGCTGACCCTGGTCGGCCTGCGCGACGGCCGCGGCGAGATCGACGACATCG
ACAACCTCGGCAACCGCCGGGTCCGCTCGGTGGGCGAGCTGCTGGAGAACCAGTACCGCGTCGGTCTGCTGCGCATGGAG
CGGGCGATCAAGGAGCGCATGAGCAGCGTCGACATCGACACGGTCATGCCGCACGACCTGATCAACGCCAAGCCGGCGGC
GGCGGCGGTGCGGGAGTTCTTCGGCTCCTCGCAGCTGTCGCAGTTCATGGACCAGACGAACCCGCTGTCCGAGATCACCC
ACAAGCGCCGCCTCTCGGCGCTGGGGCCGGGCGGCCTCACCCGCGAGCGCGCGGGCTTCGAGGTCCGCGACGTGCACCCG
ACCCACTATGGCCGGATCTGCCCGATCGAGACGCCGGAAGGCCCGAACATCGGCCTGATCAACTCGCTGGCCACCCATGC
GGTCGTGAACAAGTACGGCTTCATCGAGAGCCCGTACCGGCGCATCCGTGACGGCAAGACCACCGACGAGGTGGTCTACA
TGTCGGCCATGGAAGAGGCGAAGCACGTCATCGCCCAGGCCAACATCAAGCTCGAGAACGGCGAGATCGTCGAGGACCTG
GTCCCCGGCCGGATCAACGGCGAACCCTCGCTGCTGCCGAAGGCCGACGTCGACCTGATGGACGTCTCGCCGAAGCAGGT
CGTCTCGGTCGCCGCCTCGCTGATCCCGTTCCTCGAGAACGACGACGCCAACCGCGCCCTGATGGGCTCGAACATGCAGA
AGCAGGCCGTGCCGCTCATCCAGTCGGATGCGCCGCTGGTCGGCACCGGCATGGAGAGCATCGTGGCGGTGGACTCGGGC
GCCGTGGTCGTGGCGCGCCGCACCGGCGTGGTCGAGCAGATCGACGGCACCCGCATCGTCGTCCGCGCGACCGAGGAGAC
CGATCCCTCCAAGCCGGGCGTCGACATCTACCGCCTGCAGAAGTTCCAGCGCTCGAACACCTCGACCTGCATCAACCAGC
GTCCGCTGGTGCGGGTGGGCGACAAGATCAACGCCGGCGACGTGATCGCCGACGGCCCCTCGACCGAGCTGGGCGAACTG
GCGCTGGGCCGCAACGCCCTCGTCGCGTTCATGCCCTGGAACGGCTACAACTTCGAAGACTCGATCCTGATCTCCGAGCG
GATCGTGCGCGATGACGTCTTCACCTCGATCCACATCGAGGAGTTCGAGGTCATGGCCCGCGACACCAAGCTGGGTCCGG
AAGAGATCACCCGCGACATCCCGAACGTCGGCGAGGAGGCCCTGCGCAACCTCGACGAGGCGGGCATCGTGGCGATCGGC
GCCGAGGTCCAGCCGGGCGACATCCTGGTCGGCAAGGTGACGCCGAAGGGCGAGAGCCCGATGACGCCGGAAGAGAAGCT
GCTGCGCGCCATCTTCGGCGAGAAGGCCTCGGACGTGCGCGACACCTCGCTGCGCCTGCCGCCGGGGGTGTCGGGCACCA
TCGTGGAAGTCCGCGTCTTCAACCGCCACGGCGTCGACAAGGACGAGCGCGCGCTCGCGATCGAACGGGCCGAGATCGAC
CGCCTGGGCAAGGACCGCGACGACGAGTTCGCGATCCTGAACCGCAACATGCAGGGCCGCCTGCGTCAGCTGCTCGTCGG
CAAGACCGCCGTCTCGGGTCCGAAGGGCCTGGGCCGCGGCGAGATCACCGCCGAGAAGCTGGAGGAGATCGCCCCCGGCC
TGTGGTGGCAGATCGCCCTCGACGACGAGAAGGCGATGGGCGAGCTCGAAGCGCTGCGCAAGCAGTTCGACGACGCCCGC
AAGCGCCTCGACCGCCGCTTCGAGGACAAGGTCGACAAGCTGCAGCGCGGCGACGAGCTGCCGCCCGGCGTGATGAAGAT
GGTCAAGGTGTTCGTGGCGGTGAAGCGCAAGCTGCAGCCGGGCGACAAGATGGCCGGCCGTCACGGCAACAAGGGGGTCA
TCTCCAAGATCCTGCCGATCGAGGACATGCCCTACCTGGAGGACGGCACCAGCGTCGACATCGTGCTGAACCCGCTGGGC
GTGCCTTCGCGGATGAACGTCGGCCAGATCTTCGAGACCCACCTGGGCTGGGCCGCGGCCGGCCTCGGCAAGCAGGTCCA
GCGCCTGCTCGAGGACTGGCAGCACGGCGGGCAGAAGCAGGCGCTCATCGAGCACCTGCGCGACGTCTACGGCCCCGACG
AGGAGCTGCCGGACACCGAGGAGGAGCTGGTCGAGCTGGCCCGCAACCTGTCGAAGGGCATCCCCTTCGCCACGCCGGTG
TTCGACGGCGCCCACATCGACGACATCGAGAACCTGCTGGAGAAGGCGGGCCTCGACCGGTCGGGCCAGTCGTACCTGTA
CGACGGCCAGTCGGGCGAGCGGTTCAAGCGTCCGGTCACGGTCGGCTACATCTACATGCTGAAGCTGCACCACCTGGTCG
ACGACAAGATCCACGCCCGTTCGATCGGCCCGTACTCGCTCGTCACCCAGCAGCCGCTGGGCGGCAAGGCGCAGTTCGGC
GGCCAGCGCTTCGGCGAAATGGAGGTGTGGGCCCTGGAGGCCTACGGCGCCGCCTACACCCTGCAGGAGATGCTGACGGT
GAAGTCGGACGACGTGGCCGGCCGGACGAAGGTCTACGAGTCCATCGTCCGCGGCGACGACACCTTCGAGGCCGGGATCC
CGGAAAGCTTCAACGTGCTGGTCAAGGAGATGCGCTCCCTGGGCCTGAACGTGGAGCTGGAGAACAGCTGA

Upstream 100 bases:

>100_bases
GCATTCCAGCGTCCGGCTCCCGCAAGGGGGCTCGAGGGTGGACGCAGGATGAAAAGCTCGACGGTGGGACTCCGTTCCCA
GCCGTCCTCAAGGGATCAAA

Downstream 100 bases:

>100_bases
CGGGCGCCTACATGCCCTCCTTCGCAGCGATGCGGGGGAGGGCGGCCCCACCCGTCCTGCTTTGAAATTCACGCGGGCTC
CGTCCCGCAGAAGGAACCAA

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1356; Mature: 1355

Protein sequence:

>1356_residues
MAQSFTGKKRIRKSFGRIPEAVQMPNLIEVQRSSYEQFLQREVRAGERRDEGIEAVFKSVFPIKDFNERAVLEYVSYEFE
EPKYDVEECVQRDMTYAAPLKVKLRLIVFETDEETGARSVKDIKEQDVYMGDIPLMTEKGTFIVNGTQRVIVSQMHRSPG
VFFDHDKGKTHASGKLLFAARVIPYRGSWLDFEFDAKDIVYVRIDRRRKLPATTFLMALGMDGEEILSTFYETVPYEKKG
DGWATPYKPERWRGVKPEFPLIDADTGEEIAPAGQKISARNAKKFADNGLKTLLLAPEALTGRYLAKDLVNFETGEIYAE
AGDELDPTLLAALEEQGFTTLDVLDIDEVTVGAYIRNTLRVDKNTAREDALFDIYRVMRPGEPPTVEAAEAMFKSLFFDS
ERYDLSSVGRVKMNMRLELDCPDDVRVIRKEDVIAVLLTLVGLRDGRGEIDDIDNLGNRRVRSVGELLENQYRVGLLRME
RAIKERMSSVDIDTVMPHDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHP
THYGRICPIETPEGPNIGLINSLATHAVVNKYGFIESPYRRIRDGKTTDEVVYMSAMEEAKHVIAQANIKLENGEIVEDL
VPGRINGEPSLLPKADVDLMDVSPKQVVSVAASLIPFLENDDANRALMGSNMQKQAVPLIQSDAPLVGTGMESIVAVDSG
AVVVARRTGVVEQIDGTRIVVRATEETDPSKPGVDIYRLQKFQRSNTSTCINQRPLVRVGDKINAGDVIADGPSTELGEL
ALGRNALVAFMPWNGYNFEDSILISERIVRDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVGEEALRNLDEAGIVAIG
AEVQPGDILVGKVTPKGESPMTPEEKLLRAIFGEKASDVRDTSLRLPPGVSGTIVEVRVFNRHGVDKDERALAIERAEID
RLGKDRDDEFAILNRNMQGRLRQLLVGKTAVSGPKGLGRGEITAEKLEEIAPGLWWQIALDDEKAMGELEALRKQFDDAR
KRLDRRFEDKVDKLQRGDELPPGVMKMVKVFVAVKRKLQPGDKMAGRHGNKGVISKILPIEDMPYLEDGTSVDIVLNPLG
VPSRMNVGQIFETHLGWAAAGLGKQVQRLLEDWQHGGQKQALIEHLRDVYGPDEELPDTEEELVELARNLSKGIPFATPV
FDGAHIDDIENLLEKAGLDRSGQSYLYDGQSGERFKRPVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFG
GQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELENS

Sequences:

>Translated_1356_residues
MAQSFTGKKRIRKSFGRIPEAVQMPNLIEVQRSSYEQFLQREVRAGERRDEGIEAVFKSVFPIKDFNERAVLEYVSYEFE
EPKYDVEECVQRDMTYAAPLKVKLRLIVFETDEETGARSVKDIKEQDVYMGDIPLMTEKGTFIVNGTQRVIVSQMHRSPG
VFFDHDKGKTHASGKLLFAARVIPYRGSWLDFEFDAKDIVYVRIDRRRKLPATTFLMALGMDGEEILSTFYETVPYEKKG
DGWATPYKPERWRGVKPEFPLIDADTGEEIAPAGQKISARNAKKFADNGLKTLLLAPEALTGRYLAKDLVNFETGEIYAE
AGDELDPTLLAALEEQGFTTLDVLDIDEVTVGAYIRNTLRVDKNTAREDALFDIYRVMRPGEPPTVEAAEAMFKSLFFDS
ERYDLSSVGRVKMNMRLELDCPDDVRVIRKEDVIAVLLTLVGLRDGRGEIDDIDNLGNRRVRSVGELLENQYRVGLLRME
RAIKERMSSVDIDTVMPHDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHP
THYGRICPIETPEGPNIGLINSLATHAVVNKYGFIESPYRRIRDGKTTDEVVYMSAMEEAKHVIAQANIKLENGEIVEDL
VPGRINGEPSLLPKADVDLMDVSPKQVVSVAASLIPFLENDDANRALMGSNMQKQAVPLIQSDAPLVGTGMESIVAVDSG
AVVVARRTGVVEQIDGTRIVVRATEETDPSKPGVDIYRLQKFQRSNTSTCINQRPLVRVGDKINAGDVIADGPSTELGEL
ALGRNALVAFMPWNGYNFEDSILISERIVRDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVGEEALRNLDEAGIVAIG
AEVQPGDILVGKVTPKGESPMTPEEKLLRAIFGEKASDVRDTSLRLPPGVSGTIVEVRVFNRHGVDKDERALAIERAEID
RLGKDRDDEFAILNRNMQGRLRQLLVGKTAVSGPKGLGRGEITAEKLEEIAPGLWWQIALDDEKAMGELEALRKQFDDAR
KRLDRRFEDKVDKLQRGDELPPGVMKMVKVFVAVKRKLQPGDKMAGRHGNKGVISKILPIEDMPYLEDGTSVDIVLNPLG
VPSRMNVGQIFETHLGWAAAGLGKQVQRLLEDWQHGGQKQALIEHLRDVYGPDEELPDTEEELVELARNLSKGIPFATPV
FDGAHIDDIENLLEKAGLDRSGQSYLYDGQSGERFKRPVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFG
GQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELENS
>Mature_1355_residues
AQSFTGKKRIRKSFGRIPEAVQMPNLIEVQRSSYEQFLQREVRAGERRDEGIEAVFKSVFPIKDFNERAVLEYVSYEFEE
PKYDVEECVQRDMTYAAPLKVKLRLIVFETDEETGARSVKDIKEQDVYMGDIPLMTEKGTFIVNGTQRVIVSQMHRSPGV
FFDHDKGKTHASGKLLFAARVIPYRGSWLDFEFDAKDIVYVRIDRRRKLPATTFLMALGMDGEEILSTFYETVPYEKKGD
GWATPYKPERWRGVKPEFPLIDADTGEEIAPAGQKISARNAKKFADNGLKTLLLAPEALTGRYLAKDLVNFETGEIYAEA
GDELDPTLLAALEEQGFTTLDVLDIDEVTVGAYIRNTLRVDKNTAREDALFDIYRVMRPGEPPTVEAAEAMFKSLFFDSE
RYDLSSVGRVKMNMRLELDCPDDVRVIRKEDVIAVLLTLVGLRDGRGEIDDIDNLGNRRVRSVGELLENQYRVGLLRMER
AIKERMSSVDIDTVMPHDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPT
HYGRICPIETPEGPNIGLINSLATHAVVNKYGFIESPYRRIRDGKTTDEVVYMSAMEEAKHVIAQANIKLENGEIVEDLV
PGRINGEPSLLPKADVDLMDVSPKQVVSVAASLIPFLENDDANRALMGSNMQKQAVPLIQSDAPLVGTGMESIVAVDSGA
VVVARRTGVVEQIDGTRIVVRATEETDPSKPGVDIYRLQKFQRSNTSTCINQRPLVRVGDKINAGDVIADGPSTELGELA
LGRNALVAFMPWNGYNFEDSILISERIVRDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVGEEALRNLDEAGIVAIGA
EVQPGDILVGKVTPKGESPMTPEEKLLRAIFGEKASDVRDTSLRLPPGVSGTIVEVRVFNRHGVDKDERALAIERAEIDR
LGKDRDDEFAILNRNMQGRLRQLLVGKTAVSGPKGLGRGEITAEKLEEIAPGLWWQIALDDEKAMGELEALRKQFDDARK
RLDRRFEDKVDKLQRGDELPPGVMKMVKVFVAVKRKLQPGDKMAGRHGNKGVISKILPIEDMPYLEDGTSVDIVLNPLGV
PSRMNVGQIFETHLGWAAAGLGKQVQRLLEDWQHGGQKQALIEHLRDVYGPDEELPDTEEELVELARNLSKGIPFATPVF
DGAHIDDIENLLEKAGLDRSGQSYLYDGQSGERFKRPVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGG
QRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELENS

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI238908505, Length=293, Percent_Identity=29.3515358361775, Blast_Score=128, Evalue=3e-29,
Organism=Homo sapiens, GI238908503, Length=293, Percent_Identity=29.3515358361775, Blast_Score=128, Evalue=3e-29,
Organism=Homo sapiens, GI4505941, Length=245, Percent_Identity=33.0612244897959, Blast_Score=128, Evalue=4e-29,
Organism=Homo sapiens, GI33469941, Length=321, Percent_Identity=28.9719626168224, Blast_Score=126, Evalue=1e-28,
Organism=Homo sapiens, GI212286172, Length=321, Percent_Identity=28.9719626168224, Blast_Score=126, Evalue=2e-28,
Organism=Escherichia coli, GI1790419, Length=1361, Percent_Identity=59.2211609110948, Blast_Score=1628, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=245, Percent_Identity=32.2448979591837, Blast_Score=125, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17506623, Length=236, Percent_Identity=33.8983050847458, Blast_Score=122, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25144348, Length=293, Percent_Identity=29.0102389078498, Blast_Score=117, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6324781, Length=293, Percent_Identity=30.0341296928328, Blast_Score=132, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6324725, Length=306, Percent_Identity=29.0849673202614, Blast_Score=127, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6325267, Length=246, Percent_Identity=31.7073170731707, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI17647877, Length=244, Percent_Identity=32.3770491803279, Blast_Score=126, Evalue=1e-28,
Organism=Drosophila melanogaster, GI17136444, Length=245, Percent_Identity=31.4285714285714, Blast_Score=119, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136446, Length=316, Percent_Identity=29.746835443038, Blast_Score=116, Evalue=9e-26,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 151284; Mature: 151153

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQSFTGKKRIRKSFGRIPEAVQMPNLIEVQRSSYEQFLQREVRAGERRDEGIEAVFKSV
CCCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FPIKDFNERAVLEYVSYEFEEPKYDVEECVQRDMTYAAPLKVKLRLIVFETDEETGARSV
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCHHHH
KDIKEQDVYMGDIPLMTEKGTFIVNGTQRVIVSQMHRSPGVFFDHDKGKTHASGKLLFAA
HHHHHCCCEECCCCEEECCCCEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEE
RVIPYRGSWLDFEFDAKDIVYVRIDRRRKLPATTFLMALGMDGEEILSTFYETVPYEKKG
EECCCCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
DGWATPYKPERWRGVKPEFPLIDADTGEEIAPAGQKISARNAKKFADNGLKTLLLAPEAL
CCCCCCCCCHHCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCHHH
TGRYLAKDLVNFETGEIYAEAGDELDPTLLAALEEQGFTTLDVLDIDEVTVGAYIRNTLR
HHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
VDKNTAREDALFDIYRVMRPGEPPTVEAAEAMFKSLFFDSERYDLSSVGRVKMNMRLELD
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHCCCEEEEEEEEEEC
CPDDVRVIRKEDVIAVLLTLVGLRDGRGEIDDIDNLGNRRVRSVGELLENQYRVGLLRME
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RAIKERMSSVDIDTVMPHDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSA
HHHHHHHHHCCCHHCCCHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
LGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATHAVVNKYGFIESPYR
CCCCCCCHHHCCCEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHH
RIRDGKTTDEVVYMSAMEEAKHVIAQANIKLENGEIVEDLVPGRINGEPSLLPKADVDLM
HHHCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHCCCCCCCCCCCCCCCCCCEE
DVSPKQVVSVAASLIPFLENDDANRALMGSNMQKQAVPLIQSDAPLVGTGMESIVAVDSG
CCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCCCCCCCEEECCCHHEEEECCC
AVVVARRTGVVEQIDGTRIVVRATEETDPSKPGVDIYRLQKFQRSNTSTCINQRPLVRVG
CEEEEECCCCCEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCEEEC
DKINAGDVIADGPSTELGELALGRNALVAFMPWNGYNFEDSILISERIVRDDVFTSIHIE
CCCCCCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHEEEHH
EFEVMARDTKLGPEEITRDIPNVGEEALRNLDEAGIVAIGAEVQPGDILVGKVTPKGESP
HHHHHHHHCCCCHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCC
MTPEEKLLRAIFGEKASDVRDTSLRLPPGVSGTIVEVRVFNRHGVDKDERALAIERAEID
CCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
RLGKDRDDEFAILNRNMQGRLRQLLVGKTAVSGPKGLGRGEITAEKLEEIAPGLWWQIAL
HCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEEE
DDEKAMGELEALRKQFDDARKRLDRRFEDKVDKLQRGDELPPGVMKMVKVFVAVKRKLQP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
GDKMAGRHGNKGVISKILPIEDMPYLEDGTSVDIVLNPLGVPSRMNVGQIFETHLGWAAA
CHHHCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
GLGKQVQRLLEDWQHGGQKQALIEHLRDVYGPDEELPDTEEELVELARNLSKGIPFATPV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
FDGAHIDDIENLLEKAGLDRSGQSYLYDGQSGERFKRPVTVGYIYMLKLHHLVDDKIHAR
CCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCCHHCCCCHHHHHHHHHHHHHHCCCHHHC
SIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYE
CCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHHCCCCCCHHHHHHH
SIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELENS
HHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
AQSFTGKKRIRKSFGRIPEAVQMPNLIEVQRSSYEQFLQREVRAGERRDEGIEAVFKSV
CCCCCHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
FPIKDFNERAVLEYVSYEFEEPKYDVEECVQRDMTYAAPLKVKLRLIVFETDEETGARSV
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCHHHH
KDIKEQDVYMGDIPLMTEKGTFIVNGTQRVIVSQMHRSPGVFFDHDKGKTHASGKLLFAA
HHHHHCCCEECCCCEEECCCCEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEE
RVIPYRGSWLDFEFDAKDIVYVRIDRRRKLPATTFLMALGMDGEEILSTFYETVPYEKKG
EECCCCCCEEEEEECCCCEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHHHCCCCCCC
DGWATPYKPERWRGVKPEFPLIDADTGEEIAPAGQKISARNAKKFADNGLKTLLLAPEAL
CCCCCCCCCHHCCCCCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCCEEEEECCHHH
TGRYLAKDLVNFETGEIYAEAGDELDPTLLAALEEQGFTTLDVLDIDEVTVGAYIRNTLR
HHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHH
VDKNTAREDALFDIYRVMRPGEPPTVEAAEAMFKSLFFDSERYDLSSVGRVKMNMRLELD
CCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHCCCEEEEEEEEEEC
CPDDVRVIRKEDVIAVLLTLVGLRDGRGEIDDIDNLGNRRVRSVGELLENQYRVGLLRME
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHH
RAIKERMSSVDIDTVMPHDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSA
HHHHHHHHHCCCHHCCCHHHHCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHH
LGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATHAVVNKYGFIESPYR
CCCCCCCHHHCCCEEEECCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHH
RIRDGKTTDEVVYMSAMEEAKHVIAQANIKLENGEIVEDLVPGRINGEPSLLPKADVDLM
HHHCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCHHHHHCCCCCCCCCCCCCCCCCCEE
DVSPKQVVSVAASLIPFLENDDANRALMGSNMQKQAVPLIQSDAPLVGTGMESIVAVDSG
CCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCCCCCCCEEECCCHHEEEECCC
AVVVARRTGVVEQIDGTRIVVRATEETDPSKPGVDIYRLQKFQRSNTSTCINQRPLVRVG
CEEEEECCCCCEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCHHHCCCCCEEEC
DKINAGDVIADGPSTELGELALGRNALVAFMPWNGYNFEDSILISERIVRDDVFTSIHIE
CCCCCCCEEECCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHEEEHH
EFEVMARDTKLGPEEITRDIPNVGEEALRNLDEAGIVAIGAEVQPGDILVGKVTPKGESP
HHHHHHHHCCCCHHHHHHHCCCHHHHHHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCC
MTPEEKLLRAIFGEKASDVRDTSLRLPPGVSGTIVEVRVFNRHGVDKDERALAIERAEID
CCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHH
RLGKDRDDEFAILNRNMQGRLRQLLVGKTAVSGPKGLGRGEITAEKLEEIAPGLWWQIAL
HCCCCCCCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCEEEEEE
DDEKAMGELEALRKQFDDARKRLDRRFEDKVDKLQRGDELPPGVMKMVKVFVAVKRKLQP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCC
GDKMAGRHGNKGVISKILPIEDMPYLEDGTSVDIVLNPLGVPSRMNVGQIFETHLGWAAA
CHHHCCCCCCCCHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
GLGKQVQRLLEDWQHGGQKQALIEHLRDVYGPDEELPDTEEELVELARNLSKGIPFATPV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
FDGAHIDDIENLLEKAGLDRSGQSYLYDGQSGERFKRPVTVGYIYMLKLHHLVDDKIHAR
CCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCCHHCCCCHHHHHHHHHHHHHHCCCHHHC
SIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYE
CCCCHHHEECCCCCCCCCCCCCCCCCEEEEEEEHHCHHHHHHHHHHHCCCCCCHHHHHHH
SIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELENS
HHHCCCCCCCCCCCHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA