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The map label for this gene is gst [C]

Identifier: 197104589

GI number: 197104589

Start: 1285693

End: 1286328

Strand: Direct

Name: gst [C]

Synonym: PHZ_c1123

Alternate gene names: 197104589

Gene position: 1285693-1286328 (Clockwise)

Preceding gene: 197104588

Following gene: 197104590

Centisome position: 32.17

GC content: 70.28

Gene sequence:

>636_bases
ATGATCGAACTCTGGCACTGCCCCGACGCCCGCTCGTTCCGGCCGCTCTGGGCCCTGGAGGAGCTGGACCTGCCGTACGA
GCTGCACCTGCTGCCGTTCCCGCCGCGGGTGCGCGCGCCGGAATACCTGGAGGTCAATCCGCTGGGGACCATCCCGGCGA
TGCGCGACGGCGAGACGTTCATGAGCGAGTCCGCGGCCATCGTGCAGTACCTCGTCACCCGCTACGGCCCCAGCGACCTG
GCCGTGCCGGTGGAGGACCCCGCCTACGGCGCGTGGCTGAACTGGCTGCACTTCGGCGAGGCGACCCTGACCTTTCCGCA
GACCCTGGTGCTGCGCTACCGCACCTTCGAGCCAGGCAAGGCCGAGGTCGTGGCCGACGACTACGCCAAGTGGTTCCTGA
GCCGCCTGCGGCACGTGGACCGGGCGCTTTCGGCGGGCGACTGGCTCTGCGCCGGCCGGTTCACGGCGGCGGACATCTCG
GTCGGCTACGCCCTCCTGCTGGCGAACCACCTGGGCCTGAGCGAGAGCTTCAGCCCACAGGTGAAGGCCTATTGGGAGCG
GCTGAAGGCCCGGCCCGCCTTCCAGGCCGCCAAGGCCGCGCAGAAGATGGAGCTGTCCGAGGCGCTGTCGTCCTGA

Upstream 100 bases:

>100_bases
AGGCGATGATCCCGGGCACCGAGATGAGCATGCCGCCCCTTCGCAAACCGCGTGACCGCCAGGCGGTGATCCGCTTCCTC
CAGACCACGGCGAGCCCCCG

Downstream 100 bases:

>100_bases
CCCGCCGGCTCGGGAATCGGCCTAGGACAGGGGCGTTGCGCACGATGTCCACGGTCCGATGAAGCGGCTGGTCTTCGATC
TCGACGGCACCCTGGCCCTC

Product: glutathione S-transferase

Products: HX; R-S-Glutathione; S-(2,4-dinitrophenyl)glutathione [C]

Alternate protein names: Glutathione S-Transferase Domain-Containing Protein; Glutathione S-Transferase-Like Protein; Glutathione S-Transferase Domain Protein; Glutathione S-Transferase-Like; Glutathione S-Transferase Family Protein; Glutathione Transferase; Glutathione S-Transferase III; Glutathione S-Transferase Protein; Glutathione S-Transferase N-Terminal Domain Protein; Glutathione S-Transferase Domain; Glutathione S Transferase; Glutathione S-Transferase N-Terminal Domain; Transcriptional Regulator; Gst Protein; GSH-Dependent Dehydroascorbate Reductase

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MIELWHCPDARSFRPLWALEELDLPYELHLLPFPPRVRAPEYLEVNPLGTIPAMRDGETFMSESAAIVQYLVTRYGPSDL
AVPVEDPAYGAWLNWLHFGEATLTFPQTLVLRYRTFEPGKAEVVADDYAKWFLSRLRHVDRALSAGDWLCAGRFTAADIS
VGYALLLANHLGLSESFSPQVKAYWERLKARPAFQAAKAAQKMELSEALSS

Sequences:

>Translated_211_residues
MIELWHCPDARSFRPLWALEELDLPYELHLLPFPPRVRAPEYLEVNPLGTIPAMRDGETFMSESAAIVQYLVTRYGPSDL
AVPVEDPAYGAWLNWLHFGEATLTFPQTLVLRYRTFEPGKAEVVADDYAKWFLSRLRHVDRALSAGDWLCAGRFTAADIS
VGYALLLANHLGLSESFSPQVKAYWERLKARPAFQAAKAAQKMELSEALSS
>Mature_211_residues
MIELWHCPDARSFRPLWALEELDLPYELHLLPFPPRVRAPEYLEVNPLGTIPAMRDGETFMSESAAIVQYLVTRYGPSDL
AVPVEDPAYGAWLNWLHFGEATLTFPQTLVLRYRTFEPGKAEVVADDYAKWFLSRLRHVDRALSAGDWLCAGRFTAADIS
VGYALLLANHLGLSESFSPQVKAYWERLKARPAFQAAKAAQKMELSEALSS

Specific function: Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles. [C]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.18 [C]

Molecular weight: Translated: 23813; Mature: 23813

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00019 ACTININ_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIELWHCPDARSFRPLWALEELDLPYELHLLPFPPRVRAPEYLEVNPLGTIPAMRDGETF
CCEEECCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCHHH
MSESAAIVQYLVTRYGPSDLAVPVEDPAYGAWLNWLHFGEATLTFPQTLVLRYRTFEPGK
HHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCHHHEEEEEECCCCCC
AEVVADDYAKWFLSRLRHVDRALSAGDWLCAGRFTAADISVGYALLLANHLGLSESFSPQ
CEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEHHHHHHHHHHHHHHCCCCCCCCHH
VKAYWERLKARPAFQAAKAAQKMELSEALSS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIELWHCPDARSFRPLWALEELDLPYELHLLPFPPRVRAPEYLEVNPLGTIPAMRDGETF
CCEEECCCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCCCCCHHH
MSESAAIVQYLVTRYGPSDLAVPVEDPAYGAWLNWLHFGEATLTFPQTLVLRYRTFEPGK
HHHHHHHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCHHHEEEEEECCCCCC
AEVVADDYAKWFLSRLRHVDRALSAGDWLCAGRFTAADISVGYALLLANHLGLSESFSPQ
CEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEHHHHHHHHHHHHHHCCCCCCCCHH
VKAYWERLKARPAFQAAKAAQKMELSEALSS
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; Glutathione; 1-chloro-2,4-dinitrobenzene; reduced glutathione [C]

Specific reaction: RX + Glutathione = HX + R-S-Glutathione 1-chloro-2,4-dinitrobenzene + reduced glutathione = S-(2,4-dinitrophenyl)glutathione [C]

General reaction: Aryl group transfer [C]

Inhibitor: Cd2+; CibacronBlue; Co2+; Cu2+; Hematin; Hg2+; Ni2+; Sulfophthaleins; Tributyl tinacetate; Triethyl tinbromide; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA