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The map label for this gene is vgb [H]

Identifier: 197104587

GI number: 197104587

Start: 1284366

End: 1285328

Strand: Direct

Name: vgb [H]

Synonym: PHZ_c1121

Alternate gene names: 197104587

Gene position: 1284366-1285328 (Clockwise)

Preceding gene: 197104586

Following gene: 197104588

Centisome position: 32.14

GC content: 72.38

Gene sequence:

>963_bases
ATGCGCAAGCTCCTGATCGCCGCCGCGGCGCTCGCGGCCGGCATGATGGCGGGCTGCGGCCCGGCCGCGGCCCAGCAGGC
GCAGTACTTCGAGGTTCCGAAGGGCGGGCGGCCGCACGACGTCGCCGCCGCCCCGGACGGGACCGTCTGGTACACGGCCC
AGCGGACGGGGAAGCTGGGAATCTTGGACCCGAAGACGGGCCGGGCCGAAGAGGTCCCGCTGGGCGAGGGCTCGGCGCCG
CATGGCGTCATCGTGGGCCCGGACGGTGCGGCGTGGATCACCGACGGGGGCCTCAACGCCATCGTCCGCGTCGATCCCAA
GACCCGGGCCGTGAAGGCCTGGAAGCTGCCGGAGGACACCGGCTACGCCAATCTCAACACCGCCGCGTTCGACGGCCGGG
GCCGCATCTGGTTCACCGGCCAGACCGGCTTCTACGGCCGGCTCGATCCGGCGAGCGGGGACATGAAGGTCTGGAAGGCG
CCCGAGGGCCGCGGGCCCTATGGCATCACGGCCACGCCCGCGGGCGAGATCTACTACGTCTCTCTGGCCGGCAGCCATCT
CGCCAAGGTGGACCTGGAGAGCGGGGCGGCCACGGTCATCGAGCCGCCGACGCCGGACCAGGGCGCGCGCCGCGTCTGGT
CCGACAGCCAGGGGCGGCTGTGGATCAGCGAGTGGAACTCGGGCCAGCTCAGCCGCTACGACCCGAAGGCGGGGGCCTGG
AAGAGCTGGATGCCGCCGGGCGAGAAGCCTCGCACCTACTCCGTCTACGTCGACGAGACCGACAAGGTCTGGATCACCGA
CTTCGCCGCCAACGCCATCCTGCGTTTCGACCCGGCGACCGAGACGTTCCAGAGCTTCCCCAGCGACCGGCCGGGCGCGA
ACGTGCGCCAGATGCTGGGCCGCCCGGGCGAGGCCTGGGGGGCGGAGTCCGGGACCGACCGCCTCGTCGTGATCCGGTAC
TAG

Upstream 100 bases:

>100_bases
CCCGAGGAGGTCACGCGCCTGATCCTGGAATGGCTGAAGGGCCTGTGAGCGGCGGGATTCCGCGGTAGGGTTCGGGCCAG
GACACAAGGGAGGACAGGCG

Downstream 100 bases:

>100_bases
GCGTGCTGGCGGCAAGCCTCGCTCTGATGCTGGCCGCCTCGGCGCCCTCGGCCGCCGAGGGCGCGCGGGTGTTCCAGCGC
TGCTTCTCCTGCCATTCGGT

Product: streptogramin lyase

Products: NA

Alternate protein names: Streptogramin B lyase [H]

Number of amino acids: Translated: 320; Mature: 320

Protein sequence:

>320_residues
MRKLLIAAAALAAGMMAGCGPAAAQQAQYFEVPKGGRPHDVAAAPDGTVWYTAQRTGKLGILDPKTGRAEEVPLGEGSAP
HGVIVGPDGAAWITDGGLNAIVRVDPKTRAVKAWKLPEDTGYANLNTAAFDGRGRIWFTGQTGFYGRLDPASGDMKVWKA
PEGRGPYGITATPAGEIYYVSLAGSHLAKVDLESGAATVIEPPTPDQGARRVWSDSQGRLWISEWNSGQLSRYDPKAGAW
KSWMPPGEKPRTYSVYVDETDKVWITDFAANAILRFDPATETFQSFPSDRPGANVRQMLGRPGEAWGAESGTDRLVVIRY

Sequences:

>Translated_320_residues
MRKLLIAAAALAAGMMAGCGPAAAQQAQYFEVPKGGRPHDVAAAPDGTVWYTAQRTGKLGILDPKTGRAEEVPLGEGSAP
HGVIVGPDGAAWITDGGLNAIVRVDPKTRAVKAWKLPEDTGYANLNTAAFDGRGRIWFTGQTGFYGRLDPASGDMKVWKA
PEGRGPYGITATPAGEIYYVSLAGSHLAKVDLESGAATVIEPPTPDQGARRVWSDSQGRLWISEWNSGQLSRYDPKAGAW
KSWMPPGEKPRTYSVYVDETDKVWITDFAANAILRFDPATETFQSFPSDRPGANVRQMLGRPGEAWGAESGTDRLVVIRY
>Mature_320_residues
MRKLLIAAAALAAGMMAGCGPAAAQQAQYFEVPKGGRPHDVAAAPDGTVWYTAQRTGKLGILDPKTGRAEEVPLGEGSAP
HGVIVGPDGAAWITDGGLNAIVRVDPKTRAVKAWKLPEDTGYANLNTAAFDGRGRIWFTGQTGFYGRLDPASGDMKVWKA
PEGRGPYGITATPAGEIYYVSLAGSHLAKVDLESGAATVIEPPTPDQGARRVWSDSQGRLWISEWNSGQLSRYDPKAGAW
KSWMPPGEKPRTYSVYVDETDKVWITDFAANAILRFDPATETFQSFPSDRPGANVRQMLGRPGEAWGAESGTDRLVVIRY

Specific function: Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid [H]

COG id: COG4257

COG function: function code V; Streptogramin lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the vgb family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011042 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 34334; Mature: 34334

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLLIAAAALAAGMMAGCGPAAAQQAQYFEVPKGGRPHDVAAAPDGTVWYTAQRTGKLG
CCHHHHHHHHHHHHHHHCCCHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCEEE
ILDPKTGRAEEVPLGEGSAPHGVIVGPDGAAWITDGGLNAIVRVDPKTRAVKAWKLPEDT
EECCCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCEEEEEECCCCCEEEEEECCCCC
GYANLNTAAFDGRGRIWFTGQTGFYGRLDPASGDMKVWKAPEGRGPYGITATPAGEIYYV
CCCCCEEEEECCCCEEEEEECCCCCEEECCCCCCEEEEECCCCCCCCCEEECCCCCEEEE
SLAGSHLAKVDLESGAATVIEPPTPDQGARRVWSDSQGRLWISEWNSGQLSRYDPKAGAW
EECCCEEEEEEECCCCEEEECCCCCCHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCCC
KSWMPPGEKPRTYSVYVDETDKVWITDFAANAILRFDPATETFQSFPSDRPGANVRQMLG
CCCCCCCCCCCEEEEEECCCCCEEEEEECCCEEEEECCCHHHHHHCCCCCCCCHHHHHHC
RPGEAWGAESGTDRLVVIRY
CCCCCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MRKLLIAAAALAAGMMAGCGPAAAQQAQYFEVPKGGRPHDVAAAPDGTVWYTAQRTGKLG
CCHHHHHHHHHHHHHHHCCCHHHHCCCEEEECCCCCCCCCCCCCCCCCEEEEEECCCEEE
ILDPKTGRAEEVPLGEGSAPHGVIVGPDGAAWITDGGLNAIVRVDPKTRAVKAWKLPEDT
EECCCCCCCCCCCCCCCCCCCCEEECCCCCEEEECCCCEEEEEECCCCCEEEEEECCCCC
GYANLNTAAFDGRGRIWFTGQTGFYGRLDPASGDMKVWKAPEGRGPYGITATPAGEIYYV
CCCCCEEEEECCCCEEEEEECCCCCEEECCCCCCEEEEECCCCCCCCCEEECCCCCEEEE
SLAGSHLAKVDLESGAATVIEPPTPDQGARRVWSDSQGRLWISEWNSGQLSRYDPKAGAW
EECCCEEEEEEECCCCEEEECCCCCCHHHHHHCCCCCCEEEEEECCCCCCEEECCCCCCC
KSWMPPGEKPRTYSVYVDETDKVWITDFAANAILRFDPATETFQSFPSDRPGANVRQMLG
CCCCCCCCCCCEEEEEECCCCCEEEEEECCCEEEEECCCHHHHHHCCCCCCCCHHHHHHC
RPGEAWGAESGTDRLVVIRY
CCCCCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA