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The map label for this gene is cysW [H]

Identifier: 197104569

GI number: 197104569

Start: 1253915

End: 1254754

Strand: Direct

Name: cysW [H]

Synonym: PHZ_c1103

Alternate gene names: 197104569

Gene position: 1253915-1254754 (Clockwise)

Preceding gene: 197104568

Following gene: 197104570

Centisome position: 31.38

GC content: 69.52

Gene sequence:

>840_bases
ATGACGGGGTCGCGAATCCGACTGCCGGGCCTTGCGCCCCTGTTCCTCGCGCTCGCCCTGGCCGTCCTCGGGGTGCTGAT
CGTCCTGCCGCTGGGCGTGGTGTTCCAGCAGGCGCTCTCCAAGGGACTGGGCGCCTACATCGAGCCGCTCCGGCAGCCCG
ACGCCCTGGCGGCGATCCGGCTGACGCTGACGGTGGCCGCCATCTCGGTCCCGCTGAACGCGGTGTTCGGCGTGGCCGCC
GCCTGGGCGATCGCCCGCTTCGAGTTCCGGGGCAAGAGCCTGCTCGTCACCTTCATCGACCTGCCGTTCTCGATGTCGCC
GGTGGTCTCGGGCCTGGTCTGGGTGCTGCTGTTCGGGGCCCAGGGCTGGTTCGGCGAGATCCTGCTGCAACACGACGTCA
GGATCATCTTCGCGACGTCGGGCCTCGTCCTGGCCACGGTGCTGGTCACGCTGCCGTTCGTCGCCCGCGAGCTCATCCCG
CTGATGCAGGGGCAGGGCTCGGACGAGGAGGCGGCGGCGCTGACCCTGGGGGCCGGCGGCTGGACCACGTTCTGGCGGGT
CACCCTGCCCAACATCCGCTGGGCGCTGCTGTACGGCGTCCTGCTCTGCAACGCCCGCGCGATGGGCGAGTTCGGCGCGG
TCTCGGTGGTCTCGGGCAGCATCCGGGGCCTGACCACCACTTTGCCGCTCCACGTCGAGGTGCTCTACAATGACTACGAA
TTCGTCGGCGCTTTCGCGGCGGCCTCCATCCTCGCGGGCCTCGGGCTCGTCACCCTCGTCCTCAAGACGGTCCTCGAATG
GCGACATGCCGGTGAACTTGCCGCAAGCTGCAAACACTGA

Upstream 100 bases:

>100_bases
CCGGCGCGGCGGCCATCGGCCTGGCCATGCTGGTCATCTCGTTCGGGGCCCTCCTGGCGGTGAACGCCGCCCAGATGGCG
ACGGCGGGGCGGGGGCGCGC

Downstream 100 bases:

>100_bases
CGGGGCCGCGCTGGAGATCCGCGGGGTCTCCAAGACGTTCGGCCGCTTCCCGGCGCTGCGGGACGTCTCGCTGCGGGCGC
GGGACAAGGAGTTCCTGGCG

Product: sulfate ABC transporter,permease protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTGSRIRLPGLAPLFLALALAVLGVLIVLPLGVVFQQALSKGLGAYIEPLRQPDALAAIRLTLTVAAISVPLNAVFGVAA
AWAIARFEFRGKSLLVTFIDLPFSMSPVVSGLVWVLLFGAQGWFGEILLQHDVRIIFATSGLVLATVLVTLPFVARELIP
LMQGQGSDEEAAALTLGAGGWTTFWRVTLPNIRWALLYGVLLCNARAMGEFGAVSVVSGSIRGLTTTLPLHVEVLYNDYE
FVGAFAAASILAGLGLVTLVLKTVLEWRHAGELAASCKH

Sequences:

>Translated_279_residues
MTGSRIRLPGLAPLFLALALAVLGVLIVLPLGVVFQQALSKGLGAYIEPLRQPDALAAIRLTLTVAAISVPLNAVFGVAA
AWAIARFEFRGKSLLVTFIDLPFSMSPVVSGLVWVLLFGAQGWFGEILLQHDVRIIFATSGLVLATVLVTLPFVARELIP
LMQGQGSDEEAAALTLGAGGWTTFWRVTLPNIRWALLYGVLLCNARAMGEFGAVSVVSGSIRGLTTTLPLHVEVLYNDYE
FVGAFAAASILAGLGLVTLVLKTVLEWRHAGELAASCKH
>Mature_278_residues
TGSRIRLPGLAPLFLALALAVLGVLIVLPLGVVFQQALSKGLGAYIEPLRQPDALAAIRLTLTVAAISVPLNAVFGVAAA
WAIARFEFRGKSLLVTFIDLPFSMSPVVSGLVWVLLFGAQGWFGEILLQHDVRIIFATSGLVLATVLVTLPFVARELIPL
MQGQGSDEEAAALTLGAGGWTTFWRVTLPNIRWALLYGVLLCNARAMGEFGAVSVVSGSIRGLTTTLPLHVEVLYNDYEF
VGAFAAASILAGLGLVTLVLKTVLEWRHAGELAASCKH

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4208

COG function: function code P; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082099, Length=253, Percent_Identity=52.9644268774704, Blast_Score=270, Evalue=6e-74,
Organism=Escherichia coli, GI1788764, Length=206, Percent_Identity=35.9223300970874, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1786980, Length=173, Percent_Identity=35.2601156069364, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011866
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29630; Mature: 29498

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGSRIRLPGLAPLFLALALAVLGVLIVLPLGVVFQQALSKGLGAYIEPLRQPDALAAIR
CCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHH
LTLTVAAISVPLNAVFGVAAAWAIARFEFRGKSLLVTFIDLPFSMSPVVSGLVWVLLFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCC
QGWFGEILLQHDVRIIFATSGLVLATVLVTLPFVARELIPLMQGQGSDEEAAALTLGAGG
CCHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCC
WTTFWRVTLPNIRWALLYGVLLCNARAMGEFGAVSVVSGSIRGLTTTLPLHVEVLYNDYE
CEEEEEEECCCHHHHHHHHHHHHCCHHCCCCCCHHEECCCCCCEEEECCEEEEEEECCHH
FVGAFAAASILAGLGLVTLVLKTVLEWRHAGELAASCKH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TGSRIRLPGLAPLFLALALAVLGVLIVLPLGVVFQQALSKGLGAYIEPLRQPDALAAIR
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHH
LTLTVAAISVPLNAVFGVAAAWAIARFEFRGKSLLVTFIDLPFSMSPVVSGLVWVLLFGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCC
QGWFGEILLQHDVRIIFATSGLVLATVLVTLPFVARELIPLMQGQGSDEEAAALTLGAGG
CCHHHHHHHHCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCC
WTTFWRVTLPNIRWALLYGVLLCNARAMGEFGAVSVVSGSIRGLTTTLPLHVEVLYNDYE
CEEEEEEECCCHHHHHHHHHHHHCCHHCCCCCCHHEECCCCCCEEEECCEEEEEEECCHH
FVGAFAAASILAGLGLVTLVLKTVLEWRHAGELAASCKH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1708375 [H]