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The map label for this gene is purQ [H]

Identifier: 197104479

GI number: 197104479

Start: 1128315

End: 1128980

Strand: Reverse

Name: purQ [H]

Synonym: PHZ_c1013

Alternate gene names: 197104479

Gene position: 1128980-1128315 (Counterclockwise)

Preceding gene: 197104480

Following gene: 197104478

Centisome position: 28.25

GC content: 70.57

Gene sequence:

>666_bases
ATGACCAAAGCCGCCGTCATCGTCTTCCCCGGCTCCAACTGCGACCGGGACTGCAAGGTCGCCATCGAGCGCGCCACGGG
CGCCCGGGTCGACATGGTCTGGCACGGGGAGACCGAGCTTCCCTCGGGCGTGGACCTGATCGTCCTGCCGGGCGGGTTCT
CGTACGGCGACTACCTGCGCTGCGGCGCCATGGCGGCGCTCTCGCCGATCATGCCCGAGGTGAAGGCCGCGGCCGAACGT
GGCGTCGCCACCGTGGGCATCTGCAACGGCTTCCAGGTCCTGTGCGAGGCGGGCCTGCTGCCCGGCGCCCTGCTGCGCAA
CGAGAAGCTCAAGTACGTCTGCAAGCCGGTGGAGCTGGAGGTGGTCAATTCCCAGACCCGCTTCACCGCCGGCTACCAGG
GCCGCCGCCAGGCCGTGATGACCGTGGGCAACGGCGAGGGCAACTTCTTCGCCGACGAGGCCACGCTGGACCGGCTGGAG
GGCGAGGGCCAGGTGGTGTTCCGCTACGCCGACAATCCCAACGGCTCGGCGCGCGACATCGCCGGCATCGTCAACGCGCG
CGGCAACGTGCTGGGCATGATGCCCCACCCCGACCGAGCGTTCGAGGCCGAGCTCGGGTCGGCGGACGGCGCCATCCTCT
TCCAGAGCGCCCTCGCCAGCGCCTGA

Upstream 100 bases:

>100_bases
GGCTACGACGAGCTCCACGCCTATCTCGACGGCCTCAAGACCTGGCGGCGCAAATGAGCGCGCTTGACGTAGAGGCCCGG
CTCGACCACCTGAGACGCCC

Downstream 100 bases:

>100_bases
CGGCCGCGCTAGCGTCCCCGGCGTCGAGTTGCCCGGGGACCTCTGCATGACCTTCAAGACCCTGCTGCGCGCGGCCGCCG
CCTGCGCCGCCATCGCCCTG

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MTKAAVIVFPGSNCDRDCKVAIERATGARVDMVWHGETELPSGVDLIVLPGGFSYGDYLRCGAMAALSPIMPEVKAAAER
GVATVGICNGFQVLCEAGLLPGALLRNEKLKYVCKPVELEVVNSQTRFTAGYQGRRQAVMTVGNGEGNFFADEATLDRLE
GEGQVVFRYADNPNGSARDIAGIVNARGNVLGMMPHPDRAFEAELGSADGAILFQSALASA

Sequences:

>Translated_221_residues
MTKAAVIVFPGSNCDRDCKVAIERATGARVDMVWHGETELPSGVDLIVLPGGFSYGDYLRCGAMAALSPIMPEVKAAAER
GVATVGICNGFQVLCEAGLLPGALLRNEKLKYVCKPVELEVVNSQTRFTAGYQGRRQAVMTVGNGEGNFFADEATLDRLE
GEGQVVFRYADNPNGSARDIAGIVNARGNVLGMMPHPDRAFEAELGSADGAILFQSALASA
>Mature_220_residues
TKAAVIVFPGSNCDRDCKVAIERATGARVDMVWHGETELPSGVDLIVLPGGFSYGDYLRCGAMAALSPIMPEVKAAAERG
VATVGICNGFQVLCEAGLLPGALLRNEKLKYVCKPVELEVVNSQTRFTAGYQGRRQAVMTVGNGEGNFFADEATLDRLEG
EGQVVFRYADNPNGSARDIAGIVNARGNVLGMMPHPDRAFEAELGSADGAILFQSALASA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=227, Percent_Identity=31.2775330396476, Blast_Score=70, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6321498, Length=188, Percent_Identity=34.0425531914894, Blast_Score=69, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24582111, Length=229, Percent_Identity=27.9475982532751, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24582109, Length=229, Percent_Identity=27.9475982532751, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI17137292, Length=229, Percent_Identity=27.9475982532751, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23357; Mature: 23226

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKAAVIVFPGSNCDRDCKVAIERATGARVDMVWHGETELPSGVDLIVLPGGFSYGDYLR
CCCEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEECCCCCCCHHHH
CGAMAALSPIMPEVKAAAERGVATVGICNGFQVLCEAGLLPGALLRNEKLKYVCKPVELE
HHHHHHHHHCCHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCHHHCCCCEEEEECCEEEE
VVNSQTRFTAGYQGRRQAVMTVGNGEGNFFADEATLDRLEGEGQVVFRYADNPNGSARDI
EECCCEEEECCCCCCCEEEEEEECCCCCEEECHHHHHHCCCCCEEEEEECCCCCCCHHHH
AGIVNARGNVLGMMPHPDRAFEAELGSADGAILFQSALASA
HHHCCCCCCEEEECCCCCCHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
TKAAVIVFPGSNCDRDCKVAIERATGARVDMVWHGETELPSGVDLIVLPGGFSYGDYLR
CCEEEEEECCCCCCCCCEEEEEECCCCEEEEEECCCCCCCCCCEEEEECCCCCCCHHHH
CGAMAALSPIMPEVKAAAERGVATVGICNGFQVLCEAGLLPGALLRNEKLKYVCKPVELE
HHHHHHHHHCCHHHHHHHHCCCEEEEECCCHHHHHHCCCCCCHHHCCCCEEEEECCEEEE
VVNSQTRFTAGYQGRRQAVMTVGNGEGNFFADEATLDRLEGEGQVVFRYADNPNGSARDI
EECCCEEEECCCCCCCEEEEEEECCCCCEEECHHHHHHCCCCCEEEEEECCCCCCCHHHH
AGIVNARGNVLGMMPHPDRAFEAELGSADGAILFQSALASA
HHHCCCCCCEEEECCCCCCHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]