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The map label for this gene is fusA [C]

Identifier: 197104412

GI number: 197104412

Start: 1039982

End: 1041994

Strand: Reverse

Name: fusA [C]

Synonym: PHZ_c0946

Alternate gene names: 197104412

Gene position: 1041994-1039982 (Counterclockwise)

Preceding gene: 197104413

Following gene: 197104409

Centisome position: 26.07

GC content: 73.12

Gene sequence:

>2013_bases
ATGGCAATCCAGGAAAAGGGGTCCGTTCGGGCGCTTGCGCTCGTGGGCCCCACAAGCGCCGGCAAGACCGCCCTGATGGA
GGCCCTGCTGCACGCCACCGGCGCCGCCGACCGCCGGGGCGAGGTGGGCGACAGCAGTCCCGAGGCCAAGGCCCGCGGCC
ATTCGGTCGAGCTGAACCTGGCGGGCTTCGAGTTCATGGGCGACCGCTACGCCGTCGTCGACTGCCCCGGGTCGCTGGAG
TTCTGCGCCGAGATCGACGCCGCCCTGCCCGCCGTGGACCTGGCCGTCGTGGTGGCCGAGCCCGACCCCGCCAAGGCCGT
GCTGCTGCAGCCCACCCTGCGCGAGCTGGAGCGCCTGGGCGTGCCGCACGCCCTCTTCATCAACAAGATGGACCAGGCCC
GCGGGTCCCTCCAGGAGCTGCTGGAGGCGCTGGCCCCCGTCTCGTCCTCGCCGCTGGTGGCCCGGCAGATCCCGACGTGG
GAAGGCGACAAGGTCTCGGGCTTCATCGACCTGGCGCTCGAGCGGTGCTTCGTCTGGCGGCCGGGACAGCCCAGCCAGCA
GGTGGACATCCCCGGCGAGCTGCGCGACGCCGAGGCCGAGGCGCGCTTCCACATGCTGGAGCAGATCGCCGACTTCGACG
ACGAGCTGCTGGAGCAGCTCCTCTCCGACGTGGTCCCCAGCCGCGACGCGGTCTTCGCCGACCTCGTGCGCGAGATGAAC
GCAGGGCAGATCACGCCGGTCTTCTTCGGCTCAGCCCAGAACGGCTTCGGCGTGCGCCGCCTGCTGAAGGCGCTGCGCCA
CGAGACGCCCCCGCCATCCCGCGCCGCCGAGCGGCTGGGCGTCGAGGCGGGCGCCTATGTGCTGAAGGCCGCCTACGCCG
GCCAGTCGGGCAAGCTGGCCTACGCCCGCGTCTTCGGCGCCCCGCTGGCGGACGGGGCCGAGTTCGTTCTGCCGGACGGC
CAGAAGCAGCGCGCCGGCGGCCTCTTCGGCGTCCAGGGCGCGGCGCTGAAGAAGATCGCCGAGGCGCCGGTGGGCGAGGT
CTGCGCCATCGGCAAGGTCGAGGCCGCCCAGGCGGGCCAGATCCTCTCCACCACCGGCCGGCCGCAGCAGGTGAAGGCGA
CCGCCCGCCCGCGCCGGCCGCTGTTCGCCGTCGCCCTGATCGCCAAGAACCGCAACGACGACGTCCGCCTCTCGGGCGCG
CTCGGCAAGCTGGTCGAGGAGGACCCGGGTCTGTCGCTGACCCACGACGCCGAGGCGCGCCAGGTGCTGCTGGCCGGCCA
GGGCGAGGGGCACGTGCGGCTGGCGCTGGAGCGGCTGAAGCGGCGCTTCGGCGTCGAGATCGACACCCAGCAACCGAAGA
CCCCCTACCGCGAGACCATCCGGGGGGCGGTGACCCAGCGGGCGCGCCACAAGAAGCAGTCCGGCGGCCACGGCCAATTC
GCTGACGTGACCATCGAGGTGAAGCCCCTGCCCCGCGGCTCCGGCGTCGTCTTCCAGTCGAGGATCGTCGGCGGCGCCGT
GCCCAGGCAGTGGGTCCCGGCGGTCGAGGACGGCGTGCGCGACGGCCTCGCCCACGGGCTCCTGGGCTTCCCGGTCACCG
ACCTGGAGGTCACGCTGGTGGACGGCATGACCCACAGCGTCGACTCCTCGGAAATGGCCTTCCGCACCGCCGGGCGCCTG
GCGATCGAGGAGGCCCTGAAGGCGGCCGGCACGATCCTCCTGGAGCCGATCGAGAAGCTGGTCGTCTATTCGCCCTCGCC
GAGCGCCTCGAACGTCACCTCGGCGCTCACCGCGCGGCGGGGCCAGATCCTGGGCCTGGGGCCGCGGGAGGACTGGCGCG
GCTGGGAGCGGATCGAGGCCTACCTGCCGCAGAGCGAGCGCCAGGACCTGATCGCCGAGCTGCGCGGGCTGACCCAGGGC
CTGGGCGCCTTCGAGGCCGACTTCGACCACATGAGCGAGCTCCACGGCCGCCTCGCCGAGGAGGCCGCGAACCACGCGAG
GGAGGGAGCGTAG

Upstream 100 bases:

>100_bases
GTCGGCCGCTCATCACAAGCGCCTCGGACGCTTCCGACCCCCGCAGGTTCCGGGGGAAACGGGGGCGTCCGGGACGCCTT
CGGTGCGTGGGAGAACGACC

Downstream 100 bases:

>100_bases
GGAGCCGAGGAAGAACGCGTTCGCTCTCCTCTTTCGTCATCGCCCGGCTTGTCCGGGCGACCCAGCCTGGGGCGGCGCCG
CCCCTGCTGCGGACGGGCGT

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 670; Mature: 669

Protein sequence:

>670_residues
MAIQEKGSVRALALVGPTSAGKTALMEALLHATGAADRRGEVGDSSPEAKARGHSVELNLAGFEFMGDRYAVVDCPGSLE
FCAEIDAALPAVDLAVVVAEPDPAKAVLLQPTLRELERLGVPHALFINKMDQARGSLQELLEALAPVSSSPLVARQIPTW
EGDKVSGFIDLALERCFVWRPGQPSQQVDIPGELRDAEAEARFHMLEQIADFDDELLEQLLSDVVPSRDAVFADLVREMN
AGQITPVFFGSAQNGFGVRRLLKALRHETPPPSRAAERLGVEAGAYVLKAAYAGQSGKLAYARVFGAPLADGAEFVLPDG
QKQRAGGLFGVQGAALKKIAEAPVGEVCAIGKVEAAQAGQILSTTGRPQQVKATARPRRPLFAVALIAKNRNDDVRLSGA
LGKLVEEDPGLSLTHDAEARQVLLAGQGEGHVRLALERLKRRFGVEIDTQQPKTPYRETIRGAVTQRARHKKQSGGHGQF
ADVTIEVKPLPRGSGVVFQSRIVGGAVPRQWVPAVEDGVRDGLAHGLLGFPVTDLEVTLVDGMTHSVDSSEMAFRTAGRL
AIEEALKAAGTILLEPIEKLVVYSPSPSASNVTSALTARRGQILGLGPREDWRGWERIEAYLPQSERQDLIAELRGLTQG
LGAFEADFDHMSELHGRLAEEAANHAREGA

Sequences:

>Translated_670_residues
MAIQEKGSVRALALVGPTSAGKTALMEALLHATGAADRRGEVGDSSPEAKARGHSVELNLAGFEFMGDRYAVVDCPGSLE
FCAEIDAALPAVDLAVVVAEPDPAKAVLLQPTLRELERLGVPHALFINKMDQARGSLQELLEALAPVSSSPLVARQIPTW
EGDKVSGFIDLALERCFVWRPGQPSQQVDIPGELRDAEAEARFHMLEQIADFDDELLEQLLSDVVPSRDAVFADLVREMN
AGQITPVFFGSAQNGFGVRRLLKALRHETPPPSRAAERLGVEAGAYVLKAAYAGQSGKLAYARVFGAPLADGAEFVLPDG
QKQRAGGLFGVQGAALKKIAEAPVGEVCAIGKVEAAQAGQILSTTGRPQQVKATARPRRPLFAVALIAKNRNDDVRLSGA
LGKLVEEDPGLSLTHDAEARQVLLAGQGEGHVRLALERLKRRFGVEIDTQQPKTPYRETIRGAVTQRARHKKQSGGHGQF
ADVTIEVKPLPRGSGVVFQSRIVGGAVPRQWVPAVEDGVRDGLAHGLLGFPVTDLEVTLVDGMTHSVDSSEMAFRTAGRL
AIEEALKAAGTILLEPIEKLVVYSPSPSASNVTSALTARRGQILGLGPREDWRGWERIEAYLPQSERQDLIAELRGLTQG
LGAFEADFDHMSELHGRLAEEAANHAREGA
>Mature_669_residues
AIQEKGSVRALALVGPTSAGKTALMEALLHATGAADRRGEVGDSSPEAKARGHSVELNLAGFEFMGDRYAVVDCPGSLEF
CAEIDAALPAVDLAVVVAEPDPAKAVLLQPTLRELERLGVPHALFINKMDQARGSLQELLEALAPVSSSPLVARQIPTWE
GDKVSGFIDLALERCFVWRPGQPSQQVDIPGELRDAEAEARFHMLEQIADFDDELLEQLLSDVVPSRDAVFADLVREMNA
GQITPVFFGSAQNGFGVRRLLKALRHETPPPSRAAERLGVEAGAYVLKAAYAGQSGKLAYARVFGAPLADGAEFVLPDGQ
KQRAGGLFGVQGAALKKIAEAPVGEVCAIGKVEAAQAGQILSTTGRPQQVKATARPRRPLFAVALIAKNRNDDVRLSGAL
GKLVEEDPGLSLTHDAEARQVLLAGQGEGHVRLALERLKRRFGVEIDTQQPKTPYRETIRGAVTQRARHKKQSGGHGQFA
DVTIEVKPLPRGSGVVFQSRIVGGAVPRQWVPAVEDGVRDGLAHGLLGFPVTDLEVTLVDGMTHSVDSSEMAFRTAGRLA
IEEALKAAGTILLEPIEKLVVYSPSPSASNVTSALTARRGQILGLGPREDWRGWERIEAYLPQSERQDLIAELRGLTQGL
GAFEADFDHMSELHGRLAEEAANHAREGA

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=697, Percent_Identity=27.6901004304161, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI25306287, Length=664, Percent_Identity=24.3975903614458, Blast_Score=153, Evalue=5e-37,
Organism=Homo sapiens, GI19923640, Length=325, Percent_Identity=25.2307692307692, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI25306283, Length=325, Percent_Identity=25.2307692307692, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1789738, Length=691, Percent_Identity=28.2199710564399, Blast_Score=251, Evalue=9e-68,
Organism=Escherichia coli, GI1790835, Length=300, Percent_Identity=27.3333333333333, Blast_Score=69, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17533571, Length=678, Percent_Identity=26.401179941003, Blast_Score=241, Evalue=1e-63,
Organism=Caenorhabditis elegans, GI17556745, Length=667, Percent_Identity=21.4392803598201, Blast_Score=113, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6323098, Length=681, Percent_Identity=27.4596182085169, Blast_Score=237, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6322359, Length=771, Percent_Identity=20.7522697795071, Blast_Score=114, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24582462, Length=680, Percent_Identity=27.6470588235294, Blast_Score=239, Evalue=6e-63,
Organism=Drosophila melanogaster, GI221458488, Length=719, Percent_Identity=22.2531293463143, Blast_Score=139, Evalue=8e-33,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 71741; Mature: 71610

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIQEKGSVRALALVGPTSAGKTALMEALLHATGAADRRGEVGDSSPEAKARGHSVELNL
CCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCEEEEEE
AGFEFMGDRYAVVDCPGSLEFCAEIDAALPAVDLAVVVAEPDPAKAVLLQPTLRELERLG
CCEEECCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEEECCCCCCEEEECHHHHHHHHCC
VPHALFINKMDQARGSLQELLEALAPVSSSPLVARQIPTWEGDKVSGFIDLALERCFVWR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHEEEC
PGQPSQQVDIPGELRDAEAEARFHMLEQIADFDDELLEQLLSDVVPSRDAVFADLVREMN
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCC
AGQITPVFFGSAQNGFGVRRLLKALRHETPPPSRAAERLGVEAGAYVLKAAYAGQSGKLA
CCCCCEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCEE
YARVFGAPLADGAEFVLPDGQKQRAGGLFGVQGAALKKIAEAPVGEVCAIGKVEAAQAGQ
EEEECCCCCCCCCEEECCCCCCHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCC
ILSTTGRPQQVKATARPRRPLFAVALIAKNRNDDVRLSGALGKLVEEDPGLSLTHDAEAR
HHHCCCCCCEEECCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCCCCEECCCCCC
QVLLAGQGEGHVRLALERLKRRFGVEIDTQQPKTPYRETIRGAVTQRARHKKQSGGHGQF
EEEEECCCCCHHHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
ADVTIEVKPLPRGSGVVFQSRIVGGAVPRQWVPAVEDGVRDGLAHGLLGFPVTDLEVTLV
EEEEEEEEECCCCCCCEEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
DGMTHSVDSSEMAFRTAGRLAIEEALKAAGTILLEPIEKLVVYSPSPSASNVTSALTARR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEEECCCCCHHHHHHHHHHCC
GQILGLGPREDWRGWERIEAYLPQSERQDLIAELRGLTQGLGAFEADFDHMSELHGRLAE
CCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHH
EAANHAREGA
HHHHHHCCCC
>Mature Secondary Structure 
AIQEKGSVRALALVGPTSAGKTALMEALLHATGAADRRGEVGDSSPEAKARGHSVELNL
CCCCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCEEEEEE
AGFEFMGDRYAVVDCPGSLEFCAEIDAALPAVDLAVVVAEPDPAKAVLLQPTLRELERLG
CCEEECCCEEEEEECCCCHHHHHHHHHHCCCEEEEEEEECCCCCCEEEECHHHHHHHHCC
VPHALFINKMDQARGSLQELLEALAPVSSSPLVARQIPTWEGDKVSGFIDLALERCFVWR
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHEEEC
PGQPSQQVDIPGELRDAEAEARFHMLEQIADFDDELLEQLLSDVVPSRDAVFADLVREMN
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHCC
AGQITPVFFGSAQNGFGVRRLLKALRHETPPPSRAAERLGVEAGAYVLKAAYAGQSGKLA
CCCCCEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHCCCCCCEE
YARVFGAPLADGAEFVLPDGQKQRAGGLFGVQGAALKKIAEAPVGEVCAIGKVEAAQAGQ
EEEECCCCCCCCCEEECCCCCCHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCHHHCCC
ILSTTGRPQQVKATARPRRPLFAVALIAKNRNDDVRLSGALGKLVEEDPGLSLTHDAEAR
HHHCCCCCCEEECCCCCCCCEEEEEEEECCCCCCEEEEHHHHHHHHCCCCCCEECCCCCC
QVLLAGQGEGHVRLALERLKRRFGVEIDTQQPKTPYRETIRGAVTQRARHKKQSGGHGQF
EEEEECCCCCHHHHHHHHHHHHHCCEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCE
ADVTIEVKPLPRGSGVVFQSRIVGGAVPRQWVPAVEDGVRDGLAHGLLGFPVTDLEVTLV
EEEEEEEEECCCCCCCEEEHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
DGMTHSVDSSEMAFRTAGRLAIEEALKAAGTILLEPIEKLVVYSPSPSASNVTSALTARR
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHEEECCCCCHHHHHHHHHHCC
GQILGLGPREDWRGWERIEAYLPQSERQDLIAELRGLTQGLGAFEADFDHMSELHGRLAE
CCEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHH
EAANHAREGA
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]