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The map label for this gene is bioC [C]

Identifier: 197104233

GI number: 197104233

Start: 845784

End: 846599

Strand: Reverse

Name: bioC [C]

Synonym: PHZ_c0767

Alternate gene names: 197104233

Gene position: 846599-845784 (Counterclockwise)

Preceding gene: 197104239

Following gene: 197104230

Centisome position: 21.18

GC content: 74.39

Gene sequence:

>816_bases
ATGTCCGCTCCCCCCCGCCTCTTCGACCGCGCCCTGCACCGCAAGCGCCTCGACCGCGCCGCCCGCGACTACGCCCACGC
CGACTTCCTGCAGCGCCGGGCCGCCGAGGACGTGGCCGAGCGCCTGGCGGCGATCATGCGGGACTTCCCCGTGGCCGTCG
ACCTGTCGGCGCGCGGCGGCGCCTTCCGCGAGGCCCTGGCGGCGGGCGAGGCGAAGGACCGGGTCGGCTTCCTCGTAGAG
GGCGACCTCTCGCACCGGATGCTGGGCGGCCGCGGCGGGCCGCGCGTGGTGCTGGACGAGGAGCGCCTGCCCTTCGCCGA
CGCCAGCCTCGACCTCGTGGTCTCGACCCTGGGCCTGCACTGGACCAACGACGTCGTGGGGGCGCTGATCCAGGCGCGGC
GGGCGCTGAAGCCCGACGGGCTGTTCATCGGCGCCTTCCTGGGCGGGACGACCCTGACCGAGCTTCGCCAGTCGCTGACC
GCCGCCGAGGCCGAGATCCTGGGCGGGGCCGGCAGCCGGGTCTCGCCCTTCGCCGACAGCCGGGATGCGGCTGGCCTGCT
GCAACGGGCCGGCTTCGCCATGCCGGTGGCCGACGTGGACACGGTGAGCGTGACCTACGACCACCCGCTGAAGCTGCTCT
ACGACCTGCGCCAGATGGGCGAGACCAGCGTGCTGGCCGACCGCCACCCGCGCAAGCTGACGCGGGCGCTGCTGGACCTG
GCGTTCGACATCTACTTCCGGCGCTTCCGGACCGAGGACGGCCGCGTGCCGGCCACCTTCGAGATCATCACCCTGACCGG
CTGGGCGCCGCGCTAG

Upstream 100 bases:

>100_bases
GGCCTGGGGCGGGAAAACGAGGTCCAGCGCGCCGCGCCAGAGCGCCTGAACGCCAGGACCCGGTTTCCATCGGCCGGCGA
AATCGCCATCTTCCGCGGCC

Downstream 100 bases:

>100_bases
CTTCCCAGCAAGTGCAGCACCACCTCGCGCCGATGCGGGCGCGTGCGGTGCTCGAAGAGGTAGATCCCCTGCCAGGTCCC
GAGCGCCAGGCGGCCGCCGA

Product: biotin synthesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSAPPRLFDRALHRKRLDRAARDYAHADFLQRRAAEDVAERLAAIMRDFPVAVDLSARGGAFREALAAGEAKDRVGFLVE
GDLSHRMLGGRGGPRVVLDEERLPFADASLDLVVSTLGLHWTNDVVGALIQARRALKPDGLFIGAFLGGTTLTELRQSLT
AAEAEILGGAGSRVSPFADSRDAAGLLQRAGFAMPVADVDTVSVTYDHPLKLLYDLRQMGETSVLADRHPRKLTRALLDL
AFDIYFRRFRTEDGRVPATFEIITLTGWAPR

Sequences:

>Translated_271_residues
MSAPPRLFDRALHRKRLDRAARDYAHADFLQRRAAEDVAERLAAIMRDFPVAVDLSARGGAFREALAAGEAKDRVGFLVE
GDLSHRMLGGRGGPRVVLDEERLPFADASLDLVVSTLGLHWTNDVVGALIQARRALKPDGLFIGAFLGGTTLTELRQSLT
AAEAEILGGAGSRVSPFADSRDAAGLLQRAGFAMPVADVDTVSVTYDHPLKLLYDLRQMGETSVLADRHPRKLTRALLDL
AFDIYFRRFRTEDGRVPATFEIITLTGWAPR
>Mature_270_residues
SAPPRLFDRALHRKRLDRAARDYAHADFLQRRAAEDVAERLAAIMRDFPVAVDLSARGGAFREALAAGEAKDRVGFLVEG
DLSHRMLGGRGGPRVVLDEERLPFADASLDLVVSTLGLHWTNDVVGALIQARRALKPDGLFIGAFLGGTTLTELRQSLTA
AEAEILGGAGSRVSPFADSRDAAGLLQRAGFAMPVADVDTVSVTYDHPLKLLYDLRQMGETSVLADRHPRKLTRALLDLA
FDIYFRRFRTEDGRVPATFEIITLTGWAPR

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40018642, Length=277, Percent_Identity=39.7111913357401, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI86792933, Length=272, Percent_Identity=36.3970588235294, Blast_Score=141, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17535003, Length=275, Percent_Identity=33.8181818181818, Blast_Score=147, Evalue=8e-36,
Organism=Drosophila melanogaster, GI19922210, Length=274, Percent_Identity=39.051094890511, Blast_Score=171, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 29690; Mature: 29559

Theoretical pI: Translated: 7.94; Mature: 7.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPPRLFDRALHRKRLDRAARDYAHADFLQRRAAEDVAERLAAIMRDFPVAVDLSARGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
AFREALAAGEAKDRVGFLVEGDLSHRMLGGRGGPRVVLDEERLPFADASLDLVVSTLGLH
HHHHHHHCCCCHHCEEEEEECCCHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCC
WTNDVVGALIQARRALKPDGLFIGAFLGGTTLTELRQSLTAAEAEILGGAGSRVSPFADS
CHHHHHHHHHHHHHCCCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
RDAAGLLQRAGFAMPVADVDTVSVTYDHPLKLLYDLRQMGETSVLADRHPRKLTRALLDL
HHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHH
AFDIYFRRFRTEDGRVPATFEIITLTGWAPR
HHHHHHHHHCCCCCCCCEEEEEEEECCCCCC
>Mature Secondary Structure 
SAPPRLFDRALHRKRLDRAARDYAHADFLQRRAAEDVAERLAAIMRDFPVAVDLSARGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCC
AFREALAAGEAKDRVGFLVEGDLSHRMLGGRGGPRVVLDEERLPFADASLDLVVSTLGLH
HHHHHHHCCCCHHCEEEEEECCCHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHCCC
WTNDVVGALIQARRALKPDGLFIGAFLGGTTLTELRQSLTAAEAEILGGAGSRVSPFADS
CHHHHHHHHHHHHHCCCCCCEEEEHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
RDAAGLLQRAGFAMPVADVDTVSVTYDHPLKLLYDLRQMGETSVLADRHPRKLTRALLDL
HHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHH
AFDIYFRRFRTEDGRVPATFEIITLTGWAPR
HHHHHHHHHCCCCCCCCEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]