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The map label for this gene is tlpA [H]

Identifier: 197104102

GI number: 197104102

Start: 685608

End: 686228

Strand: Direct

Name: tlpA [H]

Synonym: PHZ_c0636

Alternate gene names: 197104102

Gene position: 685608-686228 (Clockwise)

Preceding gene: 197104099

Following gene: 197104104

Centisome position: 17.16

GC content: 70.85

Gene sequence:

>621_bases
ATGAGCGAAGGTCCAGCGGCCAGCACCAAACCCAGGAGCGTCCTGACGTGGGCCCTCTGGGGCGCAGCCCTCCTGGGCGT
CGCGGCGGTTCTCTACATCATCGCTCAGGCTTCCACCAAGCCGGCGGCGACGACGGCGGGCGCGCCGGCGGCCAAGACCC
TGATGAGCAAGTGGACTCCGCCCGAGGCGCCGACCGCGCCGCCGGACTACGCGTTCTATGACGAGGCGGGCAAGCCGGTG
CGCATCGCCGACTTCAAGGGCAAGGTCGTGGTGATGAACATCTGGGCGACTTGGTGCGCCCCCTGCAAGGTCGAGATGCC
GACGCTGGCCAAGCTGCAGGCGGCCTACGCGGGCCAGCCCGTCGAGGTGGTGGCGGTCAGCATCGATTCCGCCGGCGAGG
CGGCGGCGGCCAAGCTGTTCATCGCCAGCAACGACCCGCTGAAGTTCTACCACGACCGCGAGATGAAGCTGCCGTTCCGC
CTGCAGCCGCCCGCCCAGGGCGCGCCGACGACGGTGATCTACGGCAAGGACGGCATGGAGATGGGCCGCGTGGCCGGAGA
GGCCGACTGGGCCGGCGCCGAGGCCCGCGCCCTGGTGGACAAGGCCCTGGCCGCGGACTGA

Upstream 100 bases:

>100_bases
ACCGACCGCCCCACATGGCTTGTCCCGTGGGCGCCTGTCCCGTAGGCGTCTGGCCCGCCGGAGCGGTCCCGCCGGGCGCA
TCAGAGGAGTTGTCGGTCAT

Downstream 100 bases:

>100_bases
GAGCTCGGGGCGGGCCTCAGGCCGCCTCGGATTCCTTGACCCGTTCGGGCGCGACCGTACGCAGCAGGCTGACCAGCGAG
CTGCGGGCCTCGGGCGCGAG

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: Cytochrome c biogenesis protein tlpA [H]

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MSEGPAASTKPRSVLTWALWGAALLGVAAVLYIIAQASTKPAATTAGAPAAKTLMSKWTPPEAPTAPPDYAFYDEAGKPV
RIADFKGKVVVMNIWATWCAPCKVEMPTLAKLQAAYAGQPVEVVAVSIDSAGEAAAAKLFIASNDPLKFYHDREMKLPFR
LQPPAQGAPTTVIYGKDGMEMGRVAGEADWAGAEARALVDKALAAD

Sequences:

>Translated_206_residues
MSEGPAASTKPRSVLTWALWGAALLGVAAVLYIIAQASTKPAATTAGAPAAKTLMSKWTPPEAPTAPPDYAFYDEAGKPV
RIADFKGKVVVMNIWATWCAPCKVEMPTLAKLQAAYAGQPVEVVAVSIDSAGEAAAAKLFIASNDPLKFYHDREMKLPFR
LQPPAQGAPTTVIYGKDGMEMGRVAGEADWAGAEARALVDKALAAD
>Mature_205_residues
SEGPAASTKPRSVLTWALWGAALLGVAAVLYIIAQASTKPAATTAGAPAAKTLMSKWTPPEAPTAPPDYAFYDEAGKPVR
IADFKGKVVVMNIWATWCAPCKVEMPTLAKLQAAYAGQPVEVVAVSIDSAGEAAAAKLFIASNDPLKFYHDREMKLPFRL
QPPAQGAPTTVIYGKDGMEMGRVAGEADWAGAEARALVDKALAAD

Specific function: Involved in cytochrome aa3 assembly [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 21602; Mature: 21471

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGPAASTKPRSVLTWALWGAALLGVAAVLYIIAQASTKPAATTAGAPAAKTLMSKWTP
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCC
PEAPTAPPDYAFYDEAGKPVRIADFKGKVVVMNIWATWCAPCKVEMPTLAKLQAAYAGQP
CCCCCCCCCCCEECCCCCEEEEEECCCCEEEEEEEEHHCCCCEECCCHHHHHHHHHCCCC
VEVVAVSIDSAGEAAAAKLFIASNDPLKFYHDREMKLPFRLQPPAQGAPTTVIYGKDGME
EEEEEEEECCCCCCEEEEEEEECCCCEEEEECCCCCCCEEECCCCCCCCEEEEECCCCCH
MGRVAGEADWAGAEARALVDKALAAD
HHHHCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEGPAASTKPRSVLTWALWGAALLGVAAVLYIIAQASTKPAATTAGAPAAKTLMSKWTP
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCC
PEAPTAPPDYAFYDEAGKPVRIADFKGKVVVMNIWATWCAPCKVEMPTLAKLQAAYAGQP
CCCCCCCCCCCEECCCCCEEEEEECCCCEEEEEEEEHHCCCCEECCCHHHHHHHHHCCCC
VEVVAVSIDSAGEAAAAKLFIASNDPLKFYHDREMKLPFRLQPPAQGAPTTVIYGKDGME
EEEEEEEECCCCCCEEEEEEEECCCCEEEEECCCCCCCEEECCCCCCCCEEEEECCCCCH
MGRVAGEADWAGAEARALVDKALAAD
HHHHCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8253065; 12597275 [H]