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The map label for this gene is plsC [C]

Identifier: 197104093

GI number: 197104093

Start: 677618

End: 678322

Strand: Reverse

Name: plsC [C]

Synonym: PHZ_c0627

Alternate gene names: 197104093

Gene position: 678322-677618 (Counterclockwise)

Preceding gene: 197104094

Following gene: 197104091

Centisome position: 16.97

GC content: 69.36

Gene sequence:

>705_bases
GTGACCGCGGTCCGCTCCCTCGCCTATGTGGCGCTCTTCTATCTCTGGACGGCGGTGGTGGCGGTGCTGGCCACGCCCAT
CCTGCTCGGCCCGCGCCGCTGGACCTTCGCCCTGTTCCATTTCTGGGGCCGGGGCGTCGTCGGCATGCTGCCGATCTGCG
GTATCCGGGTGGAGGTGCGCGGACGCGAGTTCATCCCGTCGGGCCCTGCGCTCGTCGCGCCCAAGCACCAGTGCATGCTG
GACGTCTTCGCCCAGTTCACCTGGCTGCCCCGCACCGCCTTCGTGATGAAGAAGGAGCTGGCCTGGATCCCGTGGTTCGG
CTGGTACGCCGCCAAGTCCGGCGCCATCGTCATCGACCGCGAGGGCGCTTCGAAGACCATGCGCCAGGTGATCCGCGAGG
GTAAGGAGCGCTTCACCCGCGGCCAGCAGGTGGTCATCTTCCCGGAAGGCACCCGCAAGGCGCCCGGCGCCCCGCCCGAC
TACAAGCCCGGGATCGCCGCGCTCTACCGCGAGCTGGACGTGCCGGTCTATCCGGTGGCCACCAACGCCGGCGTCCACTG
GCCCGCCCACGGCTTCAAGCGCGTCCCCGGCGTCATCGTCTTCGAGTACCTGGAGCCCATTCCCCCGGGCCTGAAGCGCG
CCGAGTTCATGCGCATCCTCGAAGAGCGCATCGAGACCCGCTCCCGCGAGCTGATGAGCCTCTAG

Upstream 100 bases:

>100_bases
TCGAGTATTGCAAGTATCTGGCGATCCTCGGCCGCGAGGCGGTGCTGGGGCTCGGGCCCCGCGAAGCGCCGCTCGAGACG
GCGCAGCAGAAGGCCACGCC

Downstream 100 bases:

>100_bases
AGGCGGCTATCCCGCCGCCAGCTCCCGCGCCTCCACCAGCCCCAGCAGCTGCTCCATGCCCTGGTCGCGGACCCCAAGCT
CGCGCAGGTGCTCCACGAGG

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase; 1-Acylglycerol-3-Phosphate O-Acyltransferase; Acyltransferase; Acyltransferase Family Protein; Acyltransferase Domain Protein; 1-Acyl-SN-Glycerol-3-Phosphate Acyltransferase; N-Acylhomoserine Lactone Synthase; HdtS Protein; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferases; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Protein; Acyltransferase Domain-Containing Protein; Phospholipids Biosynthesis-Related Protein; Scaffold Protein; [Acyl-]Glycerolphosphate Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase Alpha; Acetyltransferase; Phospholipid Biosynthesis-Related Acyltransferase; Protoheme IX Farnesyltransferase; Phospholipid And Glycerol Acyltransferase; 1-Acyl-Sn-Glycerol-3-Phosphate Acetyltransferase; Acylhomoserine Lactone Synthase HdtS; 1-Acyl-Sn-Glycerol-3-Phosphate Acyltransferase PlsC; Acetyltransferase Protein; Acyltransferase Family; LPA Acyltransferase Protein

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MTAVRSLAYVALFYLWTAVVAVLATPILLGPRRWTFALFHFWGRGVVGMLPICGIRVEVRGREFIPSGPALVAPKHQCML
DVFAQFTWLPRTAFVMKKELAWIPWFGWYAAKSGAIVIDREGASKTMRQVIREGKERFTRGQQVVIFPEGTRKAPGAPPD
YKPGIAALYRELDVPVYPVATNAGVHWPAHGFKRVPGVIVFEYLEPIPPGLKRAEFMRILEERIETRSRELMSL

Sequences:

>Translated_234_residues
MTAVRSLAYVALFYLWTAVVAVLATPILLGPRRWTFALFHFWGRGVVGMLPICGIRVEVRGREFIPSGPALVAPKHQCML
DVFAQFTWLPRTAFVMKKELAWIPWFGWYAAKSGAIVIDREGASKTMRQVIREGKERFTRGQQVVIFPEGTRKAPGAPPD
YKPGIAALYRELDVPVYPVATNAGVHWPAHGFKRVPGVIVFEYLEPIPPGLKRAEFMRILEERIETRSRELMSL
>Mature_233_residues
TAVRSLAYVALFYLWTAVVAVLATPILLGPRRWTFALFHFWGRGVVGMLPICGIRVEVRGREFIPSGPALVAPKHQCMLD
VFAQFTWLPRTAFVMKKELAWIPWFGWYAAKSGAIVIDREGASKTMRQVIREGKERFTRGQQVVIFPEGTRKAPGAPPDY
KPGIAALYRELDVPVYPVATNAGVHWPAHGFKRVPGVIVFEYLEPIPPGLKRAEFMRILEERIETRSRELMSL

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0204

COG function: function code I; 1-acyl-sn-glycerol-3-phosphate acyltransferase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI5453718, Length=176, Percent_Identity=30.1136363636364, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI15100175, Length=176, Percent_Identity=30.1136363636364, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17568319, Length=182, Percent_Identity=25.8241758241758, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17564032, Length=208, Percent_Identity=27.4038461538462, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281364648, Length=178, Percent_Identity=29.2134831460674, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24582856, Length=178, Percent_Identity=29.2134831460674, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24582854, Length=178, Percent_Identity=29.2134831460674, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.51

Molecular weight: Translated: 26479; Mature: 26347

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAVRSLAYVALFYLWTAVVAVLATPILLGPRRWTFALFHFWGRGVVGMLPICGIRVEVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCEEEEEC
GREFIPSGPALVAPKHQCMLDVFAQFTWLPRTAFVMKKELAWIPWFGWYAAKSGAIVIDR
CCEECCCCCCEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHCCCCEEEEEC
EGASKTMRQVIREGKERFTRGQQVVIFPEGTRKAPGAPPDYKPGIAALYRELDVPVYPVA
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEE
TNAGVHWPAHGFKRVPGVIVFEYLEPIPPGLKRAEFMRILEERIETRSRELMSL
CCCCCCCCCCHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TAVRSLAYVALFYLWTAVVAVLATPILLGPRRWTFALFHFWGRGVVGMLPICGIRVEVR
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHCCCCEEEEEC
GREFIPSGPALVAPKHQCMLDVFAQFTWLPRTAFVMKKELAWIPWFGWYAAKSGAIVIDR
CCEECCCCCCEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHCCCCEEEEEC
EGASKTMRQVIREGKERFTRGQQVVIFPEGTRKAPGAPPDYKPGIAALYRELDVPVYPVA
CCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEEEEE
TNAGVHWPAHGFKRVPGVIVFEYLEPIPPGLKRAEFMRILEERIETRSRELMSL
CCCCCCCCCCHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA