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The map label for this gene is sdaA [H]

Identifier: 197104068

GI number: 197104068

Start: 642791

End: 644161

Strand: Reverse

Name: sdaA [H]

Synonym: PHZ_c0602

Alternate gene names: 197104068

Gene position: 644161-642791 (Counterclockwise)

Preceding gene: 197104069

Following gene: 197104067

Centisome position: 16.12

GC content: 73.01

Gene sequence:

>1371_bases
GTGAACGTCAGCGTTTTCGACCTCTTCAAGCTGGGGGTCGGCCCCTCCTCGTCCCACACCATGGGCCCCATGACCGCCGC
GGGCCGGTTCCTCGCCTGGCTGGGCGAGGACCTGGCGCGTGCGGCGCGGGTGGAGGTCGCCCTCTACGCCTCGCTGGCCC
TGACCGGCCGGGGCCACGCCACGGACCGGGCGGTGATCCTCGGCCTCGCCGGCTTCGAGCCGCGGACGCTGGATCCCGAC
GCGGCGGACCGGGCGCTCGCGCAGGTCCGCGAAAGCGGCCGGCTGCCGCTCGCCGGCCGTCACGACGTCGGCTTCGACGA
GGCCCGCGACATCCTCTGGGAGGGCCGCACCCGCCTGCCCCAGCATCCCAACGCCATGCGGCTTTCCGCCTTGGACGCCG
GGGGCGGTGTGGTGGGCGAGCGGGTCTATTTCTCGGTTGGCGGCGGCTTCGTCCGCGACGAGGACGAGATGGGCCGGAAC
GACAGCCCGGATCGCGCCCTGCCGACGCCCTATCCCTTCACCTCCGGCGCCGAGTTGCTCGAGATGGCCGAGGCCGCCGG
CCTCTCCATCGCCGAGCTGATGATGGCCAACGAGAAGGTCCGGCGCAGCCAGGCCGAGGTGGAGGCCGGCGTCGAGGAGA
TCGCCCAGGCCATGTACGCCTGCATCGACCGGGGCATGCGCGCCGAGGGCGTCCTGCCGGGCGGGCTGAACGTCCAGCGG
CGGGCGCGGCAGGTCTGGAACAGCCTGATGGACGACGCCGACCGCCGCATCGCCGACCCCCTCGCCGCCCTCGACTGGGT
CAACCTGTGGGCCCTGGCGGTGAACGAGGAGAACGCCGCCGGCGGCCGCGTGGTCACCGCCCCGACCAACGGCGCGGCGG
GCCTCTTGCCGGCCGTGCTGCGCTACTACGACCGCTTCCACCAGGGCACGCCGAAGGGCCGGCGGACCTTCCTGCTGACC
GCGGCGGCCGTCGGCGCGCTCTACAAGACCCGCGCCTCGATCTCGGGAGCCGAGGTCGGCTGCCAGGGCGAGGTAGGCGT
GGCCTGCTCCATGGCCGCGGCCGGGCTGGCGGCGGCGCTCGGCGCCAGCAACGCCCAGATCGAGAACGCCGCCGAGATCG
CCATGGAGCACAACCTCGGCCTGACCTGCGATCCGATCGGCGGCCTCGTCCAGGTGCCCTGCATCGAGCGCAACGCCATG
GGCGCGGTGAAGGCCATCGACGCCGCGCGCCTGGCCCTGCTGGGCGATGGCCAGCACACCGTCAGCCTCGACAAGGTCAT
CGCCACCATGAAGCGCACCGGCGAGGACATGAGCGCCATCTACAAGGAGACCTCGCTGGGCGGCCTGGCTGTCAACCTGG
CGGAATGCTGA

Upstream 100 bases:

>100_bases
GCCGGCCGCATGAAGCTGCCCGACGCGGACGACGACGAGTTCATCCCCCTGCCGGGCGACCCGCCCCCGCCCGCGAACCC
GATGAGCTGAGCCCGCCGAA

Downstream 100 bases:

>100_bases
GCCGCGAGTGTCGGGCCCCGATTGTCGGGACGGGCGCGCCCCGTCCGTCCTTGGGCCGTAGGGTCCATCGGACAAGCGAG
GAGACGAGACCATGCGCTAC

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MNVSVFDLFKLGVGPSSSHTMGPMTAAGRFLAWLGEDLARAARVEVALYASLALTGRGHATDRAVILGLAGFEPRTLDPD
AADRALAQVRESGRLPLAGRHDVGFDEARDILWEGRTRLPQHPNAMRLSALDAGGGVVGERVYFSVGGGFVRDEDEMGRN
DSPDRALPTPYPFTSGAELLEMAEAAGLSIAELMMANEKVRRSQAEVEAGVEEIAQAMYACIDRGMRAEGVLPGGLNVQR
RARQVWNSLMDDADRRIADPLAALDWVNLWALAVNEENAAGGRVVTAPTNGAAGLLPAVLRYYDRFHQGTPKGRRTFLLT
AAAVGALYKTRASISGAEVGCQGEVGVACSMAAAGLAAALGASNAQIENAAEIAMEHNLGLTCDPIGGLVQVPCIERNAM
GAVKAIDAARLALLGDGQHTVSLDKVIATMKRTGEDMSAIYKETSLGGLAVNLAEC

Sequences:

>Translated_456_residues
MNVSVFDLFKLGVGPSSSHTMGPMTAAGRFLAWLGEDLARAARVEVALYASLALTGRGHATDRAVILGLAGFEPRTLDPD
AADRALAQVRESGRLPLAGRHDVGFDEARDILWEGRTRLPQHPNAMRLSALDAGGGVVGERVYFSVGGGFVRDEDEMGRN
DSPDRALPTPYPFTSGAELLEMAEAAGLSIAELMMANEKVRRSQAEVEAGVEEIAQAMYACIDRGMRAEGVLPGGLNVQR
RARQVWNSLMDDADRRIADPLAALDWVNLWALAVNEENAAGGRVVTAPTNGAAGLLPAVLRYYDRFHQGTPKGRRTFLLT
AAAVGALYKTRASISGAEVGCQGEVGVACSMAAAGLAAALGASNAQIENAAEIAMEHNLGLTCDPIGGLVQVPCIERNAM
GAVKAIDAARLALLGDGQHTVSLDKVIATMKRTGEDMSAIYKETSLGGLAVNLAEC
>Mature_456_residues
MNVSVFDLFKLGVGPSSSHTMGPMTAAGRFLAWLGEDLARAARVEVALYASLALTGRGHATDRAVILGLAGFEPRTLDPD
AADRALAQVRESGRLPLAGRHDVGFDEARDILWEGRTRLPQHPNAMRLSALDAGGGVVGERVYFSVGGGFVRDEDEMGRN
DSPDRALPTPYPFTSGAELLEMAEAAGLSIAELMMANEKVRRSQAEVEAGVEEIAQAMYACIDRGMRAEGVLPGGLNVQR
RARQVWNSLMDDADRRIADPLAALDWVNLWALAVNEENAAGGRVVTAPTNGAAGLLPAVLRYYDRFHQGTPKGRRTFLLT
AAAVGALYKTRASISGAEVGCQGEVGVACSMAAAGLAAALGASNAQIENAAEIAMEHNLGLTCDPIGGLVQVPCIERNAM
GAVKAIDAARLALLGDGQHTVSLDKVIATMKRTGEDMSAIYKETSLGGLAVNLAEC

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=457, Percent_Identity=54.0481400437637, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1789161, Length=458, Percent_Identity=53.2751091703057, Blast_Score=454, Evalue=1e-129,
Organism=Escherichia coli, GI1788116, Length=455, Percent_Identity=53.6263736263736, Blast_Score=451, Evalue=1e-128,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48020; Mature: 48020

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVSVFDLFKLGVGPSSSHTMGPMTAAGRFLAWLGEDLARAARVEVALYASLALTGRGHA
CCCCCEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCC
TDRAVILGLAGFEPRTLDPDAADRALAQVRESGRLPLAGRHDVGFDEARDILWEGRTRLP
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
QHPNAMRLSALDAGGGVVGERVYFSVGGGFVRDEDEMGRNDSPDRALPTPYPFTSGAELL
CCCCCEEEEEECCCCCCCCCEEEEEECCCEEECHHHCCCCCCCCCCCCCCCCCCCCHHHH
EMAEAAGLSIAELMMANEKVRRSQAEVEAGVEEIAQAMYACIDRGMRAEGVLPGGLNVQR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
RARQVWNSLMDDADRRIADPLAALDWVNLWALAVNEENAAGGRVVTAPTNGAAGLLPAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEECCCCCCHHHHHHHH
RYYDRFHQGTPKGRRTFLLTAAAVGALYKTRASISGAEVGCQGEVGVACSMAAAGLAAAL
HHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GASNAQIENAAEIAMEHNLGLTCDPIGGLVQVPCIERNAMGAVKAIDAARLALLGDGQHT
CCCCCCHHHHHHHHHHCCCCCEECCCCCEEECCCCCCCCCHHHHHHHHHHEEEECCCCCH
VSLDKVIATMKRTGEDMSAIYKETSLGGLAVNLAEC
HHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCC
>Mature Secondary Structure
MNVSVFDLFKLGVGPSSSHTMGPMTAAGRFLAWLGEDLARAARVEVALYASLALTGRGHA
CCCCCEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCCC
TDRAVILGLAGFEPRTLDPDAADRALAQVRESGRLPLAGRHDVGFDEARDILWEGRTRLP
CCCEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
QHPNAMRLSALDAGGGVVGERVYFSVGGGFVRDEDEMGRNDSPDRALPTPYPFTSGAELL
CCCCCEEEEEECCCCCCCCCEEEEEECCCEEECHHHCCCCCCCCCCCCCCCCCCCCHHHH
EMAEAAGLSIAELMMANEKVRRSQAEVEAGVEEIAQAMYACIDRGMRAEGVLPGGLNVQR
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHH
RARQVWNSLMDDADRRIADPLAALDWVNLWALAVNEENAAGGRVVTAPTNGAAGLLPAVL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCEEEECCCCCCHHHHHHHH
RYYDRFHQGTPKGRRTFLLTAAAVGALYKTRASISGAEVGCQGEVGVACSMAAAGLAAAL
HHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
GASNAQIENAAEIAMEHNLGLTCDPIGGLVQVPCIERNAMGAVKAIDAARLALLGDGQHT
CCCCCCHHHHHHHHHHCCCCCEECCCCCEEECCCCCCCCCHHHHHHHHHHEEEECCCCCH
VSLDKVIATMKRTGEDMSAIYKETSLGGLAVNLAEC
HHHHHHHHHHHHCCHHHHHHHHHCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]