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The map label for this gene is luxQ [H]

Identifier: 197104023

GI number: 197104023

Start: 588378

End: 590228

Strand: Reverse

Name: luxQ [H]

Synonym: PHZ_c0557

Alternate gene names: 197104023

Gene position: 590228-588378 (Counterclockwise)

Preceding gene: 197104024

Following gene: 197104021

Centisome position: 14.77

GC content: 72.07

Gene sequence:

>1851_bases
ATGTCTGACGGGGCGGAAGATCGGCCGCAGATGCGCGTGGCCGTGGGCGAGGCCTACAGTCCGTATCAGCTGACGCTGGC
CGGTCTGATCTTCCCGATCGGCGGCCACATGGCCTTCAACGCCCTCGGGGCGATCGCCGCGCTGCTCCTCGGCCATCCGC
TGATCGCGGCCCTGGCGTTCGCCAGCGCGACGGCTATCGACATCGTCCAGCAACGGCTGCTGCGGCGCTGGCTGCGGACC
AGCGGCGAGGCCGACCAGGTCCGCGGCTATCGGCGCCTGGCGCTCCTCTCGGCCGTGCGCGTGAGCACCTACCTCGTCCC
CTCCGTCGCCATGGTGCTGGCGGGCGGCCTGGGCGAGATGGCCTATTTCTGGGTGCAGGCCGGCACGCTCATCGCCATCG
CCCTTTCGGCCGGGGCGCTGTCGCGGACGATCTTCTGGGGTTTCGTCACGCCGGTGCTGGTCGCCGCGGGCGTGACCTGC
CTCACGACCCTGCCGCCCGCGCCCGCCGGCGCCGTGCTGCTGGGCCTTGCGATCATGCTGGCGCTGCTGGCGATGATCTC
GAACAACACCACCCAGGCGATCAGCGGCTGGCACGCCGCGTTCAACGCCAACCTCGCCCTCGTGCGCGAGCTGGAGATCG
CCCGCGACCAGGCCGTGGCCGAGCGGGCCGCCGCGGACCGGGCGCGCGAGGAGGCCCGCCAGGCCAACCGCGCGAAGTCG
AACTTCCTGGCCACCATGAGCCACGAGATCCGCACGCCGATGAACGGCGTCCTCGGCATGGCCCAGCTCTTGAAGCGCGA
CGAGGCCGACCCGCAGCAGATCGCGCGGCTCGACACCCTGATCGACAGCGGCGAGTACCTGCTCTCGATCCTCAACGACA
TCCTGGACGTCTCGAAGATCGACGCCGGCCGGCTCGAGATCCTCTCGCGCCCCGAGGACCTGCGCCTGCTGCTGGACCGG
CTGGTCGGTTTCTGGGTCGGGCGCGCGATCGAGAAGGGGCTGGCGCTGAACCTGACGATGGGCTCCGGCGCCCCGGACTT
CGTGCTCACCGACGCCCTGCGCCTGCGGCAGATCCTGTTCAACCTCGTGGGCAACGCCCTGAAGTTCACCGAGACCGGCG
GCGTCGAGGTGATCGTCACCGGACAGCCGGCAAGGGACGGCGTCGTCCTTACCCGCTTCTCCGTGCGCGACACCGGGCCC
GGCATCGCCCCGGGCGACCTGCCCCGCCTCTTCGACCGCTTCTCGCAGGGCGACGAGGCCGAGATCCGCAAGTTCGGCGG
GACCGGGCTGGGCCTGGCCATCGTCCGGCAGCTCGCCGAGCTGATGGGCGGCGAGGTTGCGGTGGAAAGCCGCCTCGGCG
CCGGTTCGACCTTCCATGTCGAGATCCCGCTGACGCTCGCGTCCGCGGCGCCGGCCGCTCCGCTCGCGGCCGCCCCCGCC
GCGTCCCAGCCCGCCGGCGGGCTGCGGGTGCTGGCGGTGGACGACAACGCCGTGAACCTGCTGGTCCTGGAACAGGTGCT
CGGCGCCTGCGGGGCGCTGGTGGTGAAGGCGACCGGCGCGCGGGAATCCCTCGAACTCGCCGAAGGCCAGCCGTTCGACC
TGATCCTGATGGACATCCAGATGCCCGAGATGACCGGGATCGAGGCGCTGGAGCAGCTGCGCGCCGGCGCCTCGCCCAAC
CGGCTGACGCCCGTCGTGGCCCTGACCGCCGACGTGACGTCGGGCGGCCGCGAGCGCTACATGGCCCTGGGGTTCGCCGA
GCACGCCTCCAAGCCGATCCAGATCCCCGACCTGCTGGCCACCATCGACCGGGCCGTGGCCGCCCCTCCGCGCGACGCCC
GGGTCGCCTAG

Upstream 100 bases:

>100_bases
CCTCGCTGGGTAGAGCCGGCTCCACCATCGGTGGAATAGCATTGTTTTTCTAAGCTTTACCTTTTTCGCGTAAGTCTTTC
CGCCGGGAGACAAGGGCGTC

Downstream 100 bases:

>100_bases
GCGGCCGCCAGCGAGGGCAGGTCGTGCAGGGCCGGATCGAGGCCCTTGCCCATCAGGTCGATGAAGTTGTCGCGGTAGAA
GCGCCGCCGGGCCGCCTCGC

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 615

Protein sequence:

>616_residues
MSDGAEDRPQMRVAVGEAYSPYQLTLAGLIFPIGGHMAFNALGAIAALLLGHPLIAALAFASATAIDIVQQRLLRRWLRT
SGEADQVRGYRRLALLSAVRVSTYLVPSVAMVLAGGLGEMAYFWVQAGTLIAIALSAGALSRTIFWGFVTPVLVAAGVTC
LTTLPPAPAGAVLLGLAIMLALLAMISNNTTQAISGWHAAFNANLALVRELEIARDQAVAERAAADRAREEARQANRAKS
NFLATMSHEIRTPMNGVLGMAQLLKRDEADPQQIARLDTLIDSGEYLLSILNDILDVSKIDAGRLEILSRPEDLRLLLDR
LVGFWVGRAIEKGLALNLTMGSGAPDFVLTDALRLRQILFNLVGNALKFTETGGVEVIVTGQPARDGVVLTRFSVRDTGP
GIAPGDLPRLFDRFSQGDEAEIRKFGGTGLGLAIVRQLAELMGGEVAVESRLGAGSTFHVEIPLTLASAAPAAPLAAAPA
ASQPAGGLRVLAVDDNAVNLLVLEQVLGACGALVVKATGARESLELAEGQPFDLILMDIQMPEMTGIEALEQLRAGASPN
RLTPVVALTADVTSGGRERYMALGFAEHASKPIQIPDLLATIDRAVAAPPRDARVA

Sequences:

>Translated_616_residues
MSDGAEDRPQMRVAVGEAYSPYQLTLAGLIFPIGGHMAFNALGAIAALLLGHPLIAALAFASATAIDIVQQRLLRRWLRT
SGEADQVRGYRRLALLSAVRVSTYLVPSVAMVLAGGLGEMAYFWVQAGTLIAIALSAGALSRTIFWGFVTPVLVAAGVTC
LTTLPPAPAGAVLLGLAIMLALLAMISNNTTQAISGWHAAFNANLALVRELEIARDQAVAERAAADRAREEARQANRAKS
NFLATMSHEIRTPMNGVLGMAQLLKRDEADPQQIARLDTLIDSGEYLLSILNDILDVSKIDAGRLEILSRPEDLRLLLDR
LVGFWVGRAIEKGLALNLTMGSGAPDFVLTDALRLRQILFNLVGNALKFTETGGVEVIVTGQPARDGVVLTRFSVRDTGP
GIAPGDLPRLFDRFSQGDEAEIRKFGGTGLGLAIVRQLAELMGGEVAVESRLGAGSTFHVEIPLTLASAAPAAPLAAAPA
ASQPAGGLRVLAVDDNAVNLLVLEQVLGACGALVVKATGARESLELAEGQPFDLILMDIQMPEMTGIEALEQLRAGASPN
RLTPVVALTADVTSGGRERYMALGFAEHASKPIQIPDLLATIDRAVAAPPRDARVA
>Mature_615_residues
SDGAEDRPQMRVAVGEAYSPYQLTLAGLIFPIGGHMAFNALGAIAALLLGHPLIAALAFASATAIDIVQQRLLRRWLRTS
GEADQVRGYRRLALLSAVRVSTYLVPSVAMVLAGGLGEMAYFWVQAGTLIAIALSAGALSRTIFWGFVTPVLVAAGVTCL
TTLPPAPAGAVLLGLAIMLALLAMISNNTTQAISGWHAAFNANLALVRELEIARDQAVAERAAADRAREEARQANRAKSN
FLATMSHEIRTPMNGVLGMAQLLKRDEADPQQIARLDTLIDSGEYLLSILNDILDVSKIDAGRLEILSRPEDLRLLLDRL
VGFWVGRAIEKGLALNLTMGSGAPDFVLTDALRLRQILFNLVGNALKFTETGGVEVIVTGQPARDGVVLTRFSVRDTGPG
IAPGDLPRLFDRFSQGDEAEIRKFGGTGLGLAIVRQLAELMGGEVAVESRLGAGSTFHVEIPLTLASAAPAAPLAAAPAA
SQPAGGLRVLAVDDNAVNLLVLEQVLGACGALVVKATGARESLELAEGQPFDLILMDIQMPEMTGIEALEQLRAGASPNR
LTPVVALTADVTSGGRERYMALGFAEHASKPIQIPDLLATIDRAVAAPPRDARVA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=382, Percent_Identity=36.1256544502618, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1789149, Length=293, Percent_Identity=40.2730375426621, Blast_Score=208, Evalue=7e-55,
Organism=Escherichia coli, GI87081816, Length=330, Percent_Identity=37.5757575757576, Blast_Score=179, Evalue=4e-46,
Organism=Escherichia coli, GI1788713, Length=409, Percent_Identity=30.0733496332518, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI145693157, Length=286, Percent_Identity=38.1118881118881, Blast_Score=165, Evalue=9e-42,
Organism=Escherichia coli, GI1786600, Length=242, Percent_Identity=31.404958677686, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=31.063829787234, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=32.4561403508772, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1786912, Length=256, Percent_Identity=28.125, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=30.1724137931034, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=29.4372294372294, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790861, Length=212, Percent_Identity=27.3584905660377, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788279, Length=236, Percent_Identity=25.4237288135593, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=240, Percent_Identity=28.3333333333333, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1790300, Length=248, Percent_Identity=27.0161290322581, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1790551, Length=220, Percent_Identity=29.5454545454545, Blast_Score=63, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=71, Percent_Identity=50.7042253521127, Blast_Score=79, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64985; Mature: 64854

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGAEDRPQMRVAVGEAYSPYQLTLAGLIFPIGGHMAFNALGAIAALLLGHPLIAALAF
CCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHH
ASATAIDIVQQRLLRRWLRTSGEADQVRGYRRLALLSAVRVSTYLVPSVAMVLAGGLGEM
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AYFWVQAGTLIAIALSAGALSRTIFWGFVTPVLVAAGVTCLTTLPPAPAGAVLLGLAIML
HHHHHHHCHHEEEEHHCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHH
ALLAMISNNTTQAISGWHAAFNANLALVRELEIARDQAVAERAAADRAREEARQANRAKS
HHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFLATMSHEIRTPMNGVLGMAQLLKRDEADPQQIARLDTLIDSGEYLLSILNDILDVSKI
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DAGRLEILSRPEDLRLLLDRLVGFWVGRAIEKGLALNLTMGSGAPDFVLTDALRLRQILF
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHH
NLVGNALKFTETGGVEVIVTGQPARDGVVLTRFSVRDTGPGIAPGDLPRLFDRFSQGDEA
HHHCCCEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCHH
EIRKFGGTGLGLAIVRQLAELMGGEVAVESRLGAGSTFHVEIPLTLASAAPAAPLAAAPA
HHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCCC
ASQPAGGLRVLAVDDNAVNLLVLEQVLGACGALVVKATGARESLELAEGQPFDLILMDIQ
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEECCCCHHHHHCCCCCCEEEEEEEC
MPEMTGIEALEQLRAGASPNRLTPVVALTADVTSGGRERYMALGFAEHASKPIQIPDLLA
CCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHEEEEHHHCCCCCCCHHHHH
TIDRAVAAPPRDARVA
HHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SDGAEDRPQMRVAVGEAYSPYQLTLAGLIFPIGGHMAFNALGAIAALLLGHPLIAALAF
CCCCCCCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHH
ASATAIDIVQQRLLRRWLRTSGEADQVRGYRRLALLSAVRVSTYLVPSVAMVLAGGLGEM
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
AYFWVQAGTLIAIALSAGALSRTIFWGFVTPVLVAAGVTCLTTLPPAPAGAVLLGLAIML
HHHHHHHCHHEEEEHHCCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHH
ALLAMISNNTTQAISGWHAAFNANLALVRELEIARDQAVAERAAADRAREEARQANRAKS
HHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFLATMSHEIRTPMNGVLGMAQLLKRDEADPQQIARLDTLIDSGEYLLSILNDILDVSKI
HHHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHC
DAGRLEILSRPEDLRLLLDRLVGFWVGRAIEKGLALNLTMGSGAPDFVLTDALRLRQILF
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHH
NLVGNALKFTETGGVEVIVTGQPARDGVVLTRFSVRDTGPGIAPGDLPRLFDRFSQGDEA
HHHCCCEEEECCCCEEEEEECCCCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHCCCCHH
EIRKFGGTGLGLAIVRQLAELMGGEVAVESRLGAGSTFHVEIPLTLASAAPAAPLAAAPA
HHHHCCCCCHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEEEEEEEECCCCCCCCCCCCC
ASQPAGGLRVLAVDDNAVNLLVLEQVLGACGALVVKATGARESLELAEGQPFDLILMDIQ
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHEEEEEECCCCHHHHHCCCCCCEEEEEEEC
MPEMTGIEALEQLRAGASPNRLTPVVALTADVTSGGRERYMALGFAEHASKPIQIPDLLA
CCCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCHHHHHEEEEHHHCCCCCCCHHHHH
TIDRAVAAPPRDARVA
HHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA