Click here to switch to the map view.

The map label for this gene is coxC [H]

Identifier: 197104012

GI number: 197104012

Start: 578492

End: 579361

Strand: Direct

Name: coxC [H]

Synonym: PHZ_c0546

Alternate gene names: 197104012

Gene position: 578492-579361 (Clockwise)

Preceding gene: 197104011

Following gene: 197104013

Centisome position: 14.48

GC content: 65.98

Gene sequence:

>870_bases
ATGGCCGAAGGCGTCAAACACGACTATCACCTGGTCAACCCGAGCCCGTGGCCGCTGGTCGGCTCGCTGTCGGCGATGGT
GATGGCGCTCGGCGGCGTCGTGTGGATGAAGGGCCTGTTCGGCCTTCCCGCCGGCACCTGGTGGCTGTTCGCCGCGGGCC
TTGCGGGCGTGCTCTACACCATGTTCGGCTGGTGGCGGGACGTGGTGAAGGAAGCCAACGCCGGCGACCACACCCCCGTC
GTCTCGATCGGCCTGCGCTACGGCATGATCCTGTTCATCGCGTCCGAGGTGATGTTCTTCGTCGCCTGGTTCTGGATGTT
CTTCGAGATGGCGCTCTTCAACGACGTGCGCGCCGCCTCGTCGATCGAAGAGGTCCGCAACGCCTGGGCGACCTGGCCGC
CGCAGGGCGTCGAGACGGTGCCGGCGTGGGAGCTGCCGCTCGTCAACACCCTGATCCTGCTGCTCTCGGGCACCACGGTG
ACCTGGGCCCACCACGCCCTGCAGCAAGGCGACCGCAAGGGCGCCAAGATGGGCCTGATCCTGACCGTGATCCTCGGGGC
GCTGTTCACCGCGATCCAGGCGTACGAGTACCACCACATCCTGTCGCACCAGTACTTCTTCTCGGAAGAGGCCGCGAACT
CGGGCCTGTACGGCTCGACCTTCTTCATGGCCACCGGCTTCCACGGCTTCCACGTCCTGATCGGGACCATCTTCCTGCTG
GTCTGCCTGATCCGCCTGATGCGCGGCGGCTTCACGCCCCAGAAGCACTTCGGCTTCGAGGCGGCGGCCTGGTACTGGCA
CTTCGTCGACGTGGTGTGGCTGTTCCTGTTCGCCTTCATCTACGTGGTCTTCGGCGGGCCTGCGCACTAA

Upstream 100 bases:

>100_bases
GGTCGGCGCAAGGCTATAGCGTCCGCGACTTTCCGCCGTGCGACTCCATGGGGGCGCGCGTCCGGCGGCTTAAGAGACTT
GTCGAGGGGTTAGGACCGAC

Downstream 100 bases:

>100_bases
GGTGTCCCGGCCCCACCCGCTGCTGGCGGGGGCGGCCGGACGCTGCCCCAACTGCGGAGAGGGCCGCCTCTTCGAAGGCT
TCCTGGCGGTCGCGCCTCGC

Product: cytochrome c oxidase, subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MAEGVKHDYHLVNPSPWPLVGSLSAMVMALGGVVWMKGLFGLPAGTWWLFAAGLAGVLYTMFGWWRDVVKEANAGDHTPV
VSIGLRYGMILFIASEVMFFVAWFWMFFEMALFNDVRAASSIEEVRNAWATWPPQGVETVPAWELPLVNTLILLLSGTTV
TWAHHALQQGDRKGAKMGLILTVILGALFTAIQAYEYHHILSHQYFFSEEAANSGLYGSTFFMATGFHGFHVLIGTIFLL
VCLIRLMRGGFTPQKHFGFEAAAWYWHFVDVVWLFLFAFIYVVFGGPAH

Sequences:

>Translated_289_residues
MAEGVKHDYHLVNPSPWPLVGSLSAMVMALGGVVWMKGLFGLPAGTWWLFAAGLAGVLYTMFGWWRDVVKEANAGDHTPV
VSIGLRYGMILFIASEVMFFVAWFWMFFEMALFNDVRAASSIEEVRNAWATWPPQGVETVPAWELPLVNTLILLLSGTTV
TWAHHALQQGDRKGAKMGLILTVILGALFTAIQAYEYHHILSHQYFFSEEAANSGLYGSTFFMATGFHGFHVLIGTIFLL
VCLIRLMRGGFTPQKHFGFEAAAWYWHFVDVVWLFLFAFIYVVFGGPAH
>Mature_288_residues
AEGVKHDYHLVNPSPWPLVGSLSAMVMALGGVVWMKGLFGLPAGTWWLFAAGLAGVLYTMFGWWRDVVKEANAGDHTPVV
SIGLRYGMILFIASEVMFFVAWFWMFFEMALFNDVRAASSIEEVRNAWATWPPQGVETVPAWELPLVNTLILLLSGTTVT
WAHHALQQGDRKGAKMGLILTVILGALFTAIQAYEYHHILSHQYFFSEEAANSGLYGSTFFMATGFHGFHVLIGTIFLLV
CLIRLMRGGFTPQKHFGFEAAAWYWHFVDVVWLFLFAFIYVVFGGPAH

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=277, Percent_Identity=47.6534296028881, Blast_Score=223, Evalue=2e-58,
Organism=Escherichia coli, GI1786633, Length=152, Percent_Identity=30.9210526315789, Blast_Score=71, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6226542, Length=277, Percent_Identity=36.8231046931408, Blast_Score=159, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32379; Mature: 32248

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEGVKHDYHLVNPSPWPLVGSLSAMVMALGGVVWMKGLFGLPAGTWWLFAAGLAGVLYT
CCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MFGWWRDVVKEANAGDHTPVVSIGLRYGMILFIASEVMFFVAWFWMFFEMALFNDVRAAS
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIEEVRNAWATWPPQGVETVPAWELPLVNTLILLLSGTTVTWAHHALQQGDRKGAKMGLI
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHH
LTVILGALFTAIQAYEYHHILSHQYFFSEEAANSGLYGSTFFMATGFHGFHVLIGTIFLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
VCLIRLMRGGFTPQKHFGFEAAAWYWHFVDVVWLFLFAFIYVVFGGPAH
HHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AEGVKHDYHLVNPSPWPLVGSLSAMVMALGGVVWMKGLFGLPAGTWWLFAAGLAGVLYT
CCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
MFGWWRDVVKEANAGDHTPVVSIGLRYGMILFIASEVMFFVAWFWMFFEMALFNDVRAAS
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SIEEVRNAWATWPPQGVETVPAWELPLVNTLILLLSGTTVTWAHHALQQGDRKGAKMGLI
HHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHH
LTVILGALFTAIQAYEYHHILSHQYFFSEEAANSGLYGSTFFMATGFHGFHVLIGTIFLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHHHHHHHHH
VCLIRLMRGGFTPQKHFGFEAAAWYWHFVDVVWLFLFAFIYVVFGGPAH
HHHHHHHHCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]