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The map label for this gene is ctaC [H]

Identifier: 197104008

GI number: 197104008

Start: 573396

End: 574367

Strand: Direct

Name: ctaC [H]

Synonym: PHZ_c0542

Alternate gene names: 197104008

Gene position: 573396-574367 (Clockwise)

Preceding gene: 197104004

Following gene: 197104009

Centisome position: 14.35

GC content: 70.16

Gene sequence:

>972_bases
ATGAAGTCGAGGTTTCAGGGTTTGCGGGCGTTGGCGGCGGGGATCGTCGCGGCCGCTACGGGGGCGTTCTGGGGCGCGGG
CGCCCTGGCTGAAGACATGATGGGTCAGCCGACGCCGGGGGCGATCGACCTGCAGCCGGGCGTGACCCCGCTGCGCGCCG
ACGCGATCTTCTTCCACAACGCCATCCTGCTGCCGATCATCACGATCATCACCCTGTTCGTGCTGGCGCTGCTGGTGTGG
GTGATCGTGCGCTACAACAAGCGGGCCAATCCGGTCCCCGCGCGCTGGAGCCACAACACCCCCCTGGAGGTGGTCTGGAC
CCTGGTCCCGGTCCTGATCCTGGTGTTCATCGCGATCTTCTCGTTCAAGCTCCTCTACGCCTACCACGACATGCCCAAGC
CCGACCTGACGGTGAAGGCGACCGGCTACCAGTGGTACTGGGGCTATGAGTATCCCGACCAGAACGTCTCCGAGTTCGTC
TCGAACATGCTGCCGGAGGACGAGGCGCGGGCGAAGAACGTGCCGTTCCGCCTGGCCGCCACCGAACCGATGGTCGTCCC
CGTCGGCAAGACGGTCCGCGTGCTGGTCACCGGCGCCGACGTGATCCACGCCTTCGCCGTCCCCTCGTTCGGCATCATCA
CCGACGCCGTGCCCGGCCGGGTGAACGAGACCTGGTTCAAGGCCGACCGCGTGGGCACCTACTACGGCAACTGCCGCGAG
CTCTGCGGCGTGGACCACGCCTTCATGCCCATCGAGGTGCGGGTGGTGAGCCAGGCCGACTTCGACGCGTGGGTCGCCTC
GAAGGGCGGCGGCGCGCCGGCCCCGACGCCCAGCGCGCTCGACGCCGCCGCCGACGCCGCGGGCGCCGCGAACACCGAGG
CGGCTCCGGCCGCCGCCGACGCGGCCCAGCCGGCCGCCGCCGAGCCCGCCGCCACCACTCAGCCTGCGCCTGTGGCGCCG
GCCGCGAAATAA

Upstream 100 bases:

>100_bases
GGGCGGGCGCCAGCGAGCGCGCGTGCGCGCCTGTTCTCCAAGTCGGCGGAGGCTGTTCGCCCGTTCGCGAGGCGCCGCCG
GCCAACCAGACCGAGGGGAC

Downstream 100 bases:

>100_bases
GCCAGGACTAGAGTAAGATGGCACACGCCGCCGCTCACGATCACGGTCACGATCACAAGCCGCCCTTCATCACGCGTTGG
TTCTTCTCGACCAACCACAA

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MKSRFQGLRALAAGIVAAATGAFWGAGALAEDMMGQPTPGAIDLQPGVTPLRADAIFFHNAILLPIITIITLFVLALLVW
VIVRYNKRANPVPARWSHNTPLEVVWTLVPVLILVFIAIFSFKLLYAYHDMPKPDLTVKATGYQWYWGYEYPDQNVSEFV
SNMLPEDEARAKNVPFRLAATEPMVVPVGKTVRVLVTGADVIHAFAVPSFGIITDAVPGRVNETWFKADRVGTYYGNCRE
LCGVDHAFMPIEVRVVSQADFDAWVASKGGGAPAPTPSALDAAADAAGAANTEAAPAAADAAQPAAAEPAATTQPAPVAP
AAK

Sequences:

>Translated_323_residues
MKSRFQGLRALAAGIVAAATGAFWGAGALAEDMMGQPTPGAIDLQPGVTPLRADAIFFHNAILLPIITIITLFVLALLVW
VIVRYNKRANPVPARWSHNTPLEVVWTLVPVLILVFIAIFSFKLLYAYHDMPKPDLTVKATGYQWYWGYEYPDQNVSEFV
SNMLPEDEARAKNVPFRLAATEPMVVPVGKTVRVLVTGADVIHAFAVPSFGIITDAVPGRVNETWFKADRVGTYYGNCRE
LCGVDHAFMPIEVRVVSQADFDAWVASKGGGAPAPTPSALDAAADAAGAANTEAAPAAADAAQPAAAEPAATTQPAPVAP
AAK
>Mature_323_residues
MKSRFQGLRALAAGIVAAATGAFWGAGALAEDMMGQPTPGAIDLQPGVTPLRADAIFFHNAILLPIITIITLFVLALLVW
VIVRYNKRANPVPARWSHNTPLEVVWTLVPVLILVFIAIFSFKLLYAYHDMPKPDLTVKATGYQWYWGYEYPDQNVSEFV
SNMLPEDEARAKNVPFRLAATEPMVVPVGKTVRVLVTGADVIHAFAVPSFGIITDAVPGRVNETWFKADRVGTYYGNCRE
LCGVDHAFMPIEVRVVSQADFDAWVASKGGGAPAPTPSALDAAADAAGAANTEAAPAAADAAQPAAAEPAATTQPAPVAP
AAK

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=221, Percent_Identity=36.1990950226244, Blast_Score=154, Evalue=9e-38,
Organism=Escherichia coli, GI1786635, Length=213, Percent_Identity=27.2300469483568, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6226540, Length=243, Percent_Identity=39.917695473251, Blast_Score=168, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 34364; Mature: 34364

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRFQGLRALAAGIVAAATGAFWGAGALAEDMMGQPTPGAIDLQPGVTPLRADAIFFHN
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHH
AILLPIITIITLFVLALLVWVIVRYNKRANPVPARWSHNTPLEVVWTLVPVLILVFIAIF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SFKLLYAYHDMPKPDLTVKATGYQWYWGYEYPDQNVSEFVSNMLPEDEARAKNVPFRLAA
HHHHHHHHHCCCCCCEEEEECCEEEEECCCCCCCCHHHHHHHHCCCCHHHHCCCCEEEEC
TEPMVVPVGKTVRVLVTGADVIHAFAVPSFGIITDAVPGRVNETWFKADRVGTYYGNCRE
CCCEEEECCCEEEEEEECHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHCCCCHHCCHHH
LCGVDHAFMPIEVRVVSQADFDAWVASKGGGAPAPTPSALDAAADAAGAANTEAAPAAAD
HHCCCCCCCEEEEEEECCCCCHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHC
AAQPAAAEPAATTQPAPVAPAAK
CCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKSRFQGLRALAAGIVAAATGAFWGAGALAEDMMGQPTPGAIDLQPGVTPLRADAIFFHN
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHH
AILLPIITIITLFVLALLVWVIVRYNKRANPVPARWSHNTPLEVVWTLVPVLILVFIAIF
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
SFKLLYAYHDMPKPDLTVKATGYQWYWGYEYPDQNVSEFVSNMLPEDEARAKNVPFRLAA
HHHHHHHHHCCCCCCEEEEECCEEEEECCCCCCCCHHHHHHHHCCCCHHHHCCCCEEEEC
TEPMVVPVGKTVRVLVTGADVIHAFAVPSFGIITDAVPGRVNETWFKADRVGTYYGNCRE
CCCEEEECCCEEEEEEECHHHHHHHHCCCCCHHHCCCCCCCCHHHHHHHCCCCHHCCHHH
LCGVDHAFMPIEVRVVSQADFDAWVASKGGGAPAPTPSALDAAADAAGAANTEAAPAAAD
HHCCCCCCCEEEEEEECCCCCHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHC
AAQPAAAEPAATTQPAPVAPAAK
CCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2820725; 7651515; 9380672 [H]