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The map label for this gene is ubiA [H]

Identifier: 197103995

GI number: 197103995

Start: 556431

End: 557348

Strand: Direct

Name: ubiA [H]

Synonym: PHZ_c0529

Alternate gene names: 197103995

Gene position: 556431-557348 (Clockwise)

Preceding gene: 197103991

Following gene: 197103996

Centisome position: 13.92

GC content: 73.86

Gene sequence:

>918_bases
ATGACCGCGCCCCTGCCCGACGCCGCGCCCGCCAACTGGGTGGACCGACACGCGCCCGCGGGGCTCCGCCCATGGCTGAA
GCTCGGCCGCTTCGACCGGCCGACTGGCGTCTGGCTCCTGATGCTGCCCGGCTGGCAGGGCGTCGCCCTGGCCGGGCTGG
CGACGGGCCGCGGCCCCGACCTGGCGCTGCTCGCCAAGATCTTCGTGGGCGCGGCGCTGATGCGGGCGGCGGGCTGCGCC
TACAACGACATCGTCGACAGCGACATCGACGCCAAGGTCTCGCGCACGGCGGGGCGGCCGATTCCCTCGGGCCAGATCAG
CCTCCGGCAGGCGTGGGGCTTCATCGTCGCCTGCTGCCTCGTCTCCTTCGGCCTCCTGCTGACCATGCCGCCGCTCGCCA
TCGGCCTGGGCGTCGCCTCGCTGGCGCTGGTCGCGGCCTATCCGTTCATGAAGCGGATCACCTGGTGGCCGCAGGCGTGG
CTGGGCCTCACCTTCAACTGGGGCGCGCTGCTGGGCTACGCGGCGGCGGCGGGGGAGCTCTCGCTCGCGGCCGGTCTGCT
CTATGCGGCGGGCATCTTCTGGACCCTCGGCTACGACACCATCTACGCGGTCCAGGACCTCGAGGACGACGCCCTGGCCG
GCGTGAAGTCTTCGGCGCGGCGCCTGGGCTCCGGCGTGGGGCGCGGCGTCCTCGTCTTCTACCTGGTATCGCTGGCCCTG
GCGGCGGCCGCCCTGCTGCAGGGGGGCGCCTCGACCCTCGCCCTGCCGCTGTTCGCCCTCTACGCCGTCCACCTGATCCT
GCAGGCGCGGCGCGTGCGGCCGGACGCCCCGGCGCAGGCGTTGTTCCTGTTCAAGGCCAACGCCTGGGCGGGGCTGATCC
TGTTCGCCGCCGTCGTGGCGGGGGGCTTCCCGCTCTAG

Upstream 100 bases:

>100_bases
GCCGCCCCGGCGGGGGTCAAGGAACCGGGGCGGGTTCGGAGAACGCCGGATTCCGCCGCGGCATTTCCGCCACAGGCCCG
GCTCTGCTAAGTCGCCGCCC

Downstream 100 bases:

>100_bases
GCCGTTCCCCCCAAGACCGTTCCCCGGCGTCACCCTGTTTCGCGGGGCGTTCCGGGCGTAGACTGCGGCCATGGCCGTCG
CCGCCCGCGTCAGTCCGAAG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MTAPLPDAAPANWVDRHAPAGLRPWLKLGRFDRPTGVWLLMLPGWQGVALAGLATGRGPDLALLAKIFVGAALMRAAGCA
YNDIVDSDIDAKVSRTAGRPIPSGQISLRQAWGFIVACCLVSFGLLLTMPPLAIGLGVASLALVAAYPFMKRITWWPQAW
LGLTFNWGALLGYAAAAGELSLAAGLLYAAGIFWTLGYDTIYAVQDLEDDALAGVKSSARRLGSGVGRGVLVFYLVSLAL
AAAALLQGGASTLALPLFALYAVHLILQARRVRPDAPAQALFLFKANAWAGLILFAAVVAGGFPL

Sequences:

>Translated_305_residues
MTAPLPDAAPANWVDRHAPAGLRPWLKLGRFDRPTGVWLLMLPGWQGVALAGLATGRGPDLALLAKIFVGAALMRAAGCA
YNDIVDSDIDAKVSRTAGRPIPSGQISLRQAWGFIVACCLVSFGLLLTMPPLAIGLGVASLALVAAYPFMKRITWWPQAW
LGLTFNWGALLGYAAAAGELSLAAGLLYAAGIFWTLGYDTIYAVQDLEDDALAGVKSSARRLGSGVGRGVLVFYLVSLAL
AAAALLQGGASTLALPLFALYAVHLILQARRVRPDAPAQALFLFKANAWAGLILFAAVVAGGFPL
>Mature_304_residues
TAPLPDAAPANWVDRHAPAGLRPWLKLGRFDRPTGVWLLMLPGWQGVALAGLATGRGPDLALLAKIFVGAALMRAAGCAY
NDIVDSDIDAKVSRTAGRPIPSGQISLRQAWGFIVACCLVSFGLLLTMPPLAIGLGVASLALVAAYPFMKRITWWPQAWL
GLTFNWGALLGYAAAAGELSLAAGLLYAAGIFWTLGYDTIYAVQDLEDDALAGVKSSARRLGSGVGRGVLVFYLVSLALA
AAALLQGGASTLALPLFALYAVHLILQARRVRPDAPAQALFLFKANAWAGLILFAAVVAGGFPL

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=290, Percent_Identity=44.1379310344828, Blast_Score=195, Evalue=5e-50,
Organism=Escherichia coli, GI1790473, Length=272, Percent_Identity=35.6617647058824, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786631, Length=200, Percent_Identity=28.5, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17553718, Length=288, Percent_Identity=42.0138888888889, Blast_Score=187, Evalue=6e-48,
Organism=Caenorhabditis elegans, GI32565247, Length=288, Percent_Identity=38.1944444444444, Blast_Score=162, Evalue=2e-40,
Organism=Caenorhabditis elegans, GI17553720, Length=345, Percent_Identity=33.0434782608696, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI32565245, Length=146, Percent_Identity=41.0958904109589, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI32565243, Length=142, Percent_Identity=40.8450704225352, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324370, Length=296, Percent_Identity=36.1486486486487, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI21355567, Length=283, Percent_Identity=43.8162544169611, Blast_Score=191, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 31950; Mature: 31819

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPLPDAAPANWVDRHAPAGLRPWLKLGRFDRPTGVWLLMLPGWQGVALAGLATGRGPD
CCCCCCCCCCCCHHHHCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCC
LALLAKIFVGAALMRAAGCAYNDIVDSDIDAKVSRTAGRPIPSGQISLRQAWGFIVACCL
HHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
VSFGLLLTMPPLAIGLGVASLALVAAYPFMKRITWWPQAWLGLTFNWGALLGYAAAAGEL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEECHHHHHHHHHHHCHH
SLAAGLLYAAGIFWTLGYDTIYAVQDLEDDALAGVKSSARRLGSGVGRGVLVFYLVSLAL
HHHHHHHHHHHHHHHCCCHHEEHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AAAALLQGGASTLALPLFALYAVHLILQARRVRPDAPAQALFLFKANAWAGLILFAAVVA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHH
GGFPL
CCCCC
>Mature Secondary Structure 
TAPLPDAAPANWVDRHAPAGLRPWLKLGRFDRPTGVWLLMLPGWQGVALAGLATGRGPD
CCCCCCCCCCCHHHHCCCCCCCHHHHHCCCCCCCCEEEEEECCCCCHHHHHCCCCCCCC
LALLAKIFVGAALMRAAGCAYNDIVDSDIDAKVSRTAGRPIPSGQISLRQAWGFIVACCL
HHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
VSFGLLLTMPPLAIGLGVASLALVAAYPFMKRITWWPQAWLGLTFNWGALLGYAAAAGEL
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCEECHHHHHHHHHHHCHH
SLAAGLLYAAGIFWTLGYDTIYAVQDLEDDALAGVKSSARRLGSGVGRGVLVFYLVSLAL
HHHHHHHHHHHHHHHCCCHHEEHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AAAALLQGGASTLALPLFALYAVHLILQARRVRPDAPAQALFLFKANAWAGLILFAAVVA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHHHH
GGFPL
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA