Click here to switch to the map view.

The map label for this gene is czcD [H]

Identifier: 197103979

GI number: 197103979

Start: 538823

End: 539803

Strand: Reverse

Name: czcD [H]

Synonym: PHZ_c0513

Alternate gene names: 197103979

Gene position: 539803-538823 (Counterclockwise)

Preceding gene: 197103980

Following gene: 197103978

Centisome position: 13.51

GC content: 72.58

Gene sequence:

>981_bases
ATGGCCAAGGCCCACGCGCACTCCGACCACCATGACGACCATGGGCATGACCACGCTCACGGTCACGGCCATTCGCACGG
CCACGGCCACCATCATCACCACGCGCCCAAGGACATGGGCTGGGCCTTCGCGATCGGCGTGGTCCTCAACACCGGCTTTG
TCGCCGCCGAGGTGGCCGCGGGGCTCTGGACGGGCTCGCTGGCCCTCCTGGCCGACGCGGGCCACAATCTTTCCGACGTC
CTGTCCCTGCTGCTGGCCTGGGGCGCCGCGGTGCTGGCCAAGCGCGCGCCCTCGGGCCGACGCACCTACGGCCTGCGCAA
GGCGACCATCCTCGCGTCCCTCGCCAACGCCGTGCTGCTCCTGGTGGCGGTCGGCGCCATTGTCTCCGAGGCGGCGCACA
GGCTGCGCGAGCCGGCCGGGGTGGATTCCGACATCGTCATGCTGGTCGCTGGCCTGGGGGTGTTGATCAACGGGGTCACC
GCGGCGCTCTTCCTGCGGGGCAGCCACGACGACCTGAACGTCCGCGGCGCCTTCCTGCACATGGCGGCCGACGCCGCCGT
GTCGCTGGCCGTGGTGGTCGGGGCCTTCGCCATGGCCCGCACCGGCCTGCTCTGGATCGACCCGCTGCTCGGCCTGACCA
TCGCGGCGGTGATTGTCCTGGGCACCTGGGGCCTCCTGCGCGATTCCATGGACCTGGCGCTGGACGCCGCCCCCCGGGGC
ATCAACGTGGACGAGGTCCGCCGCTGGCTGGAGGCCCTGCCCGGCGTCGAGGGCGTCCACGACCTGCACATCTGGGCCAT
GAGCACCACCGAGACCGCCCTCACCGCCCACGTCCTGCGGCCGGGCAACGCCGATCCGGACCGCTTCCTGCACGACGCCT
GCGAGGGCCTGGAGCGCCGCTTCCGCATCGGCCACGCCACCCTGCAGGTGGAGACCGACGGCGCTCACGCCTGCCGGCTG
GCCCCCGCCGAGGTGGTGTGA

Upstream 100 bases:

>100_bases
CCGCGCGCCTGTCCGCCGCCACCCGCCGGGCCGAGGCCCTGGTGGGGCGGGCGCCCGCGCCGCATTGATCCTTCGCCCGG
TTCGCGAGACATAGGCTCCG

Downstream 100 bases:

>100_bases
AACCCCTCCCCCTCGCGCTCTACGGCGCGGCGACCCGCCTGCTCGAGCCGCTGGCGCCGCAGGTCCTGCAGGCCCGCGCC
CGGCGCGGCAAGGAAGACCC

Product: cation efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MAKAHAHSDHHDDHGHDHAHGHGHSHGHGHHHHHAPKDMGWAFAIGVVLNTGFVAAEVAAGLWTGSLALLADAGHNLSDV
LSLLLAWGAAVLAKRAPSGRRTYGLRKATILASLANAVLLLVAVGAIVSEAAHRLREPAGVDSDIVMLVAGLGVLINGVT
AALFLRGSHDDLNVRGAFLHMAADAAVSLAVVVGAFAMARTGLLWIDPLLGLTIAAVIVLGTWGLLRDSMDLALDAAPRG
INVDEVRRWLEALPGVEGVHDLHIWAMSTTETALTAHVLRPGNADPDRFLHDACEGLERRFRIGHATLQVETDGAHACRL
APAEVV

Sequences:

>Translated_326_residues
MAKAHAHSDHHDDHGHDHAHGHGHSHGHGHHHHHAPKDMGWAFAIGVVLNTGFVAAEVAAGLWTGSLALLADAGHNLSDV
LSLLLAWGAAVLAKRAPSGRRTYGLRKATILASLANAVLLLVAVGAIVSEAAHRLREPAGVDSDIVMLVAGLGVLINGVT
AALFLRGSHDDLNVRGAFLHMAADAAVSLAVVVGAFAMARTGLLWIDPLLGLTIAAVIVLGTWGLLRDSMDLALDAAPRG
INVDEVRRWLEALPGVEGVHDLHIWAMSTTETALTAHVLRPGNADPDRFLHDACEGLERRFRIGHATLQVETDGAHACRL
APAEVV
>Mature_325_residues
AKAHAHSDHHDDHGHDHAHGHGHSHGHGHHHHHAPKDMGWAFAIGVVLNTGFVAAEVAAGLWTGSLALLADAGHNLSDVL
SLLLAWGAAVLAKRAPSGRRTYGLRKATILASLANAVLLLVAVGAIVSEAAHRLREPAGVDSDIVMLVAGLGVLINGVTA
ALFLRGSHDDLNVRGAFLHMAADAAVSLAVVVGAFAMARTGLLWIDPLLGLTIAAVIVLGTWGLLRDSMDLALDAAPRGI
NVDEVRRWLEALPGVEGVHDLHIWAMSTTETALTAHVLRPGNADPDRFLHDACEGLERRFRIGHATLQVETDGAHACRLA
PAEVV

Specific function: Necessary for activation of the czc determinant [H]

COG id: COG1230

COG function: function code P; Co/Zn/Cd efflux system component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family. SLC30A subfamily [H]

Homologues:

Organism=Homo sapiens, GI52352805, Length=272, Percent_Identity=26.4705882352941, Blast_Score=119, Evalue=4e-27,
Organism=Homo sapiens, GI64762489, Length=308, Percent_Identity=27.9220779220779, Blast_Score=111, Evalue=8e-25,
Organism=Homo sapiens, GI289803013, Length=305, Percent_Identity=27.8688524590164, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI289803009, Length=305, Percent_Identity=27.8688524590164, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI289803007, Length=305, Percent_Identity=27.8688524590164, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI289803003, Length=305, Percent_Identity=27.8688524590164, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI21359890, Length=299, Percent_Identity=24.7491638795987, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI21361112, Length=304, Percent_Identity=27.6315789473684, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI14210520, Length=215, Percent_Identity=25.5813953488372, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI52351208, Length=153, Percent_Identity=29.4117647058824, Blast_Score=75, Evalue=6e-14,
Organism=Escherichia coli, GI1786966, Length=276, Percent_Identity=36.231884057971, Blast_Score=133, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17555794, Length=342, Percent_Identity=29.8245614035088, Blast_Score=153, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI193210990, Length=332, Percent_Identity=28.6144578313253, Blast_Score=145, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI17555796, Length=306, Percent_Identity=31.0457516339869, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI32564488, Length=292, Percent_Identity=25.6849315068493, Blast_Score=95, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323899, Length=124, Percent_Identity=39.5161290322581, Blast_Score=82, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6324892, Length=126, Percent_Identity=36.5079365079365, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320411, Length=179, Percent_Identity=34.6368715083799, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24583858, Length=359, Percent_Identity=26.4623955431755, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24584409, Length=155, Percent_Identity=29.0322580645161, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI28574430, Length=146, Percent_Identity=29.4520547945205, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24585900, Length=201, Percent_Identity=23.3830845771144, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585898, Length=201, Percent_Identity=23.3830845771144, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24585896, Length=201, Percent_Identity=23.3830845771144, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI19921672, Length=201, Percent_Identity=23.3830845771144, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24645863, Length=108, Percent_Identity=34.2592592592593, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002524 [H]

Pfam domain/function: PF01545 Cation_efflux [H]

EC number: NA

Molecular weight: Translated: 34298; Mature: 34166

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAHAHSDHHDDHGHDHAHGHGHSHGHGHHHHHAPKDMGWAFAIGVVLNTGFVAAEVAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHH
GLWTGSLALLADAGHNLSDVLSLLLAWGAAVLAKRAPSGRRTYGLRKATILASLANAVLL
HHHHCHHHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LVAVGAIVSEAAHRLREPAGVDSDIVMLVAGLGVLINGVTAALFLRGSHDDLNVRGAFLH
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHH
MAADAAVSLAVVVGAFAMARTGLLWIDPLLGLTIAAVIVLGTWGLLRDSMDLALDAAPRG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
INVDEVRRWLEALPGVEGVHDLHIWAMSTTETALTAHVLRPGNADPDRFLHDACEGLERR
CCHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHH
FRIGHATLQVETDGAHACRLAPAEVV
HHHCCEEEEEECCCCCEEECCCCCCC
>Mature Secondary Structure 
AKAHAHSDHHDDHGHDHAHGHGHSHGHGHHHHHAPKDMGWAFAIGVVLNTGFVAAEVAA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHH
GLWTGSLALLADAGHNLSDVLSLLLAWGAAVLAKRAPSGRRTYGLRKATILASLANAVLL
HHHHCHHHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LVAVGAIVSEAAHRLREPAGVDSDIVMLVAGLGVLINGVTAALFLRGSHDDLNVRGAFLH
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHH
MAADAAVSLAVVVGAFAMARTGLLWIDPLLGLTIAAVIVLGTWGLLRDSMDLALDAAPRG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
INVDEVRRWLEALPGVEGVHDLHIWAMSTTETALTAHVLRPGNADPDRFLHDACEGLERR
CCHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHHHHHEECCCCCCHHHHHHHHHHHHHHH
FRIGHATLQVETDGAHACRLAPAEVV
HHHCCEEEEEECCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]