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The map label for this gene is frpC [H]

Identifier: 197103956

GI number: 197103956

Start: 513855

End: 515765

Strand: Direct

Name: frpC [H]

Synonym: PHZ_c0490

Alternate gene names: 197103956

Gene position: 513855-515765 (Clockwise)

Preceding gene: 197103955

Following gene: 197103958

Centisome position: 12.86

GC content: 68.71

Gene sequence:

>1911_bases
ATGGCTAGCTATATTTGGGAAACTATGACGCAGGCGAACGCTGACGCGTTCACCTCGAACGACGTCATCGTCTTCACCAC
CGCGGGTGCGACTGGTGCGGCGACCGTCGTGCAATTCGTTCCGGCCACGGCGACCACGCCGGCGTCGGTCAGCATCTCGT
TCGGCGGCAAGTCGCTGAGCTTCGATGCGGCTGACGTGCAAGGCCGCACCAACCTGGCCGTCTACCCGGACGGCTCGGTC
CTGTACGTGGGCTCGACGGGCCCCGACAACGGCGCGACCTCGGGCGGCGAAAACTCCGACGGCATGTACGGCGGCAACGG
CAACGACACCCTGGGCGGCGGCAACGGCGCGGACCTGCTGCACGGCAACCTCGGCGACGACTCGCTGAACGGCGGCGGCG
GCGCTGACTCCATCTACGGCGGTCAGGGCGACGATGACATCGTCATGGGCGCCGGCGGCTTCTTCGGCCACGGCAACCTG
GGCGACGACAGCCTCGACGGCTCGGCCGGCAGCGCCACGACCGTCCAGTGGCTGTACGGCGGTCAGGGCAACGACACCGT
CGTCGGCGGCGCGGGCGCTGACCTGCTGTTCGGCAACATGGGCAACGACAGCATCGGCGGCGGCGGCGGCAACGACCAGA
TCTTCGGTGAAGACGGCAACGACACCGTCACCGCCAACGGCGGGACCGTGGTTGTCTCCGGCGGCAACGGCGCCGACAGC
ATCACCGCTACTGGCGCGGCCGTGAACCTGCAGGGCAACATCGGCGACGACACCCTCGTCGCGACCGGCGCCGGCAACGA
CATCCTCGTCGGCGGTCAGGGCAACGACATCCTGACGGCCAGCACCGGCGGCAACGAGTACCTGAACGGCAACCTGGGCG
ATGATACGCTCACGGGCGGTTCGGGCAACGATCAGCTGTACGGTGAGGCTGGCGCTGACAGCCTCGTGGGCGGCGACGGC
AACAACACGCTCATCGGCGGCGACGGCTCCGACTCGATCACCGGTGGCACCGGCAACGACAGCGTCAGCGGCGGCAACGG
CTCGGACGTGATCGTGGCTGGCGACGGCGTGAACACCATCGACGCTGGCGAAGGCAACAACTCGATCACCGCCGGCTCCG
GCAGCGACGTGATCACGGCCGGTGCGGGCAACGACACCGTCGTCGCCAACAACGGCAACAACTCGGTCTCGGTCGGCGAC
GGCGCCAACTCCGTCACGGCCGGCACGGGCAACGACACCATCACGTCGGGCTCGGGCAACGACACGATCGACGCCGGCAA
CGGCAACAACGTGATCTCCGCCGGCGACGGCGCCAACTCGATCACGGCCGGCACGGGCAACGACAACATCACGTCGGGCT
CGGGCAACGACACCATCCTCTCGGGGACGGGCGCTGACACCATCGACGCTGGCGACGGCGCGAACTCGATCACCGCTGAC
GCCGGCAACGACGTCATCACGACCGGTTCGGGCGCGGACGTCATCCTCGGCGGCGACGGCAACGACGTGATCAACTCCGG
CGCTGGCAACGACGTCATCACCGGCGGCCTGGGCAAGGACGTCATCACCGGCGGCGCCGGCGCTGACACCTTCATCTTCG
GCAACGGCGACTCGGGCGTCACGGCCGGCGGCATCGACCAGATCCGCGACTGGGAAGCCACCGACCGCCTCGACTTCGCG
GGCGCCGCGGCGACCGGCACCACCTACGTCGAAACCTCGGCGGCCGACTACGACGCCGCCAAGACGACGGCGGACGGCCT
GATCGGCACCGGCATCGACTACGTCGCGGTGCAGGTCGGTTCGGACGTGGTGATCTTCACCGACAGCGCCGGCAACAACG
GCACTGCGGAAGACGCCGTGGTCCTGGTGGGCCGCACGCTGGCCGACATCGACAGCTCGAACATCGTCTAA

Upstream 100 bases:

>100_bases
CGTGCTATGGCGCTTGGGGTAATGGACCGCCGGGATTGCCCCATCGGGGATGGGGGTCAGGCGTTCCGGGGGTCCGTGTG
ACACAGACTGGAGAGACTTA

Downstream 100 bases:

>100_bases
GCGACGATCGAGCTGAGTGCTTCTGGGGGCCGCCTTCGGGCGGCCCCCTTTTTATTGGCTGCTCGCCGGCGACGCGCGCG
GCCGCGAACCCCCTTGCCGG

Product: hemolysin-type calcium-binding region protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 636; Mature: 635

Protein sequence:

>636_residues
MASYIWETMTQANADAFTSNDVIVFTTAGATGAATVVQFVPATATTPASVSISFGGKSLSFDAADVQGRTNLAVYPDGSV
LYVGSTGPDNGATSGGENSDGMYGGNGNDTLGGGNGADLLHGNLGDDSLNGGGGADSIYGGQGDDDIVMGAGGFFGHGNL
GDDSLDGSAGSATTVQWLYGGQGNDTVVGGAGADLLFGNMGNDSIGGGGGNDQIFGEDGNDTVTANGGTVVVSGGNGADS
ITATGAAVNLQGNIGDDTLVATGAGNDILVGGQGNDILTASTGGNEYLNGNLGDDTLTGGSGNDQLYGEAGADSLVGGDG
NNTLIGGDGSDSITGGTGNDSVSGGNGSDVIVAGDGVNTIDAGEGNNSITAGSGSDVITAGAGNDTVVANNGNNSVSVGD
GANSVTAGTGNDTITSGSGNDTIDAGNGNNVISAGDGANSITAGTGNDNITSGSGNDTILSGTGADTIDAGDGANSITAD
AGNDVITTGSGADVILGGDGNDVINSGAGNDVITGGLGKDVITGGAGADTFIFGNGDSGVTAGGIDQIRDWEATDRLDFA
GAAATGTTYVETSAADYDAAKTTADGLIGTGIDYVAVQVGSDVVIFTDSAGNNGTAEDAVVLVGRTLADIDSSNIV

Sequences:

>Translated_636_residues
MASYIWETMTQANADAFTSNDVIVFTTAGATGAATVVQFVPATATTPASVSISFGGKSLSFDAADVQGRTNLAVYPDGSV
LYVGSTGPDNGATSGGENSDGMYGGNGNDTLGGGNGADLLHGNLGDDSLNGGGGADSIYGGQGDDDIVMGAGGFFGHGNL
GDDSLDGSAGSATTVQWLYGGQGNDTVVGGAGADLLFGNMGNDSIGGGGGNDQIFGEDGNDTVTANGGTVVVSGGNGADS
ITATGAAVNLQGNIGDDTLVATGAGNDILVGGQGNDILTASTGGNEYLNGNLGDDTLTGGSGNDQLYGEAGADSLVGGDG
NNTLIGGDGSDSITGGTGNDSVSGGNGSDVIVAGDGVNTIDAGEGNNSITAGSGSDVITAGAGNDTVVANNGNNSVSVGD
GANSVTAGTGNDTITSGSGNDTIDAGNGNNVISAGDGANSITAGTGNDNITSGSGNDTILSGTGADTIDAGDGANSITAD
AGNDVITTGSGADVILGGDGNDVINSGAGNDVITGGLGKDVITGGAGADTFIFGNGDSGVTAGGIDQIRDWEATDRLDFA
GAAATGTTYVETSAADYDAAKTTADGLIGTGIDYVAVQVGSDVVIFTDSAGNNGTAEDAVVLVGRTLADIDSSNIV
>Mature_635_residues
ASYIWETMTQANADAFTSNDVIVFTTAGATGAATVVQFVPATATTPASVSISFGGKSLSFDAADVQGRTNLAVYPDGSVL
YVGSTGPDNGATSGGENSDGMYGGNGNDTLGGGNGADLLHGNLGDDSLNGGGGADSIYGGQGDDDIVMGAGGFFGHGNLG
DDSLDGSAGSATTVQWLYGGQGNDTVVGGAGADLLFGNMGNDSIGGGGGNDQIFGEDGNDTVTANGGTVVVSGGNGADSI
TATGAAVNLQGNIGDDTLVATGAGNDILVGGQGNDILTASTGGNEYLNGNLGDDTLTGGSGNDQLYGEAGADSLVGGDGN
NTLIGGDGSDSITGGTGNDSVSGGNGSDVIVAGDGVNTIDAGEGNNSITAGSGSDVITAGAGNDTVVANNGNNSVSVGDG
ANSVTAGTGNDTITSGSGNDTIDAGNGNNVISAGDGANSITAGTGNDNITSGSGNDTILSGTGADTIDAGDGANSITADA
GNDVITTGSGADVILGGDGNDVINSGAGNDVITGGLGKDVITGGAGADTFIFGNGDSGVTAGGIDQIRDWEATDRLDFAG
AAATGTTYVETSAADYDAAKTTADGLIGTGIDYVAVQVGSDVVIFTDSAGNNGTAEDAVVLVGRTLADIDSSNIV

Specific function: May participate in the pathogenesis of meningococcal disease [H]

COG id: COG2931

COG function: function code Q; RTX toxins and related Ca2+-binding proteins

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Secreted (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 22 hemolysin-type calcium-binding repeats [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010566
- InterPro:   IPR018511
- InterPro:   IPR001343
- InterPro:   IPR003995
- InterPro:   IPR011049 [H]

Pfam domain/function: PF06594 HCBP_related; PF00353 HemolysinCabind [H]

EC number: NA

Molecular weight: Translated: 60515; Mature: 60384

Theoretical pI: Translated: 3.04; Mature: 3.04

Prosite motif: PS00330 HEMOLYSIN_CALCIUM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASYIWETMTQANADAFTSNDVIVFTTAGATGAATVVQFVPATATTPASVSISFGGKSLS
CCHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCEEEEEECCCEEE
FDAADVQGRTNLAVYPDGSVLYVGSTGPDNGATSGGENSDGMYGGNGNDTLGGGNGADLL
ECHHCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEE
HGNLGDDSLNGGGGADSIYGGQGDDDIVMGAGGFFGHGNLGDDSLDGSAGSATTVQWLYG
ECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
GQGNDTVVGGAGADLLFGNMGNDSIGGGGGNDQIFGEDGNDTVTANGGTVVVSGGNGADS
CCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCEECCCCCCEEEECCCEEEEECCCCCCC
ITATGAAVNLQGNIGDDTLVATGAGNDILVGGQGNDILTASTGGNEYLNGNLGDDTLTGG
EEECCEEEEEECCCCCCEEEEECCCCEEEECCCCCEEEEEECCCCCEECCCCCCCCCCCC
SGNDQLYGEAGADSLVGGDGNNTLIGGDGSDSITGGTGNDSVSGGNGSDVIVAGDGVNTI
CCCCCEEECCCCCCEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEE
DAGEGNNSITAGSGSDVITAGAGNDTVVANNGNNSVSVGDGANSVTAGTGNDTITSGSGN
ECCCCCCEEECCCCCCEEEECCCCCEEEEECCCCEEEECCCCCEEECCCCCCEEECCCCC
DTIDAGNGNNVISAGDGANSITAGTGNDNITSGSGNDTILSGTGADTIDAGDGANSITAD
CEEECCCCCCEEECCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCEECCCCCCEEEEC
AGNDVITTGSGADVILGGDGNDVINSGAGNDVITGGLGKDVITGGAGADTFIFGNGDSGV
CCCCEEEECCCCEEEECCCCCHHHCCCCCCCEEECCCCCHHEECCCCCCEEEEECCCCCC
TAGGIDQIRDWEATDRLDFAGAAATGTTYVETSAADYDAAKTTADGLIGTGIDYVAVQVG
CCCCHHHHCCCCCCCCEECCCCCCCCCEEEEECCCCCCCHHHHCCCCEECCCEEEEEEEC
SDVVIFTDSAGNNGTAEDAVVLVGRTLADIDSSNIV
CEEEEEECCCCCCCCCCCEEEEECCCEECCCCCCCC
>Mature Secondary Structure 
ASYIWETMTQANADAFTSNDVIVFTTAGATGAATVVQFVPATATTPASVSISFGGKSLS
CHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCEEEEEECCCEEE
FDAADVQGRTNLAVYPDGSVLYVGSTGPDNGATSGGENSDGMYGGNGNDTLGGGNGADLL
ECHHCCCCCCEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCEE
HGNLGDDSLNGGGGADSIYGGQGDDDIVMGAGGFFGHGNLGDDSLDGSAGSATTVQWLYG
ECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEC
GQGNDTVVGGAGADLLFGNMGNDSIGGGGGNDQIFGEDGNDTVTANGGTVVVSGGNGADS
CCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCEECCCCCCEEEECCCEEEEECCCCCCC
ITATGAAVNLQGNIGDDTLVATGAGNDILVGGQGNDILTASTGGNEYLNGNLGDDTLTGG
EEECCEEEEEECCCCCCEEEEECCCCEEEECCCCCEEEEEECCCCCEECCCCCCCCCCCC
SGNDQLYGEAGADSLVGGDGNNTLIGGDGSDSITGGTGNDSVSGGNGSDVIVAGDGVNTI
CCCCCEEECCCCCCEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCEE
DAGEGNNSITAGSGSDVITAGAGNDTVVANNGNNSVSVGDGANSVTAGTGNDTITSGSGN
ECCCCCCEEECCCCCCEEEECCCCCEEEEECCCCEEEECCCCCEEECCCCCCEEECCCCC
DTIDAGNGNNVISAGDGANSITAGTGNDNITSGSGNDTILSGTGADTIDAGDGANSITAD
CEEECCCCCCEEECCCCCCEEEECCCCCCCCCCCCCCEEEECCCCCCEECCCCCCEEEEC
AGNDVITTGSGADVILGGDGNDVINSGAGNDVITGGLGKDVITGGAGADTFIFGNGDSGV
CCCCEEEECCCCEEEECCCCCHHHCCCCCCCEEECCCCCHHEECCCCCCEEEEECCCCCC
TAGGIDQIRDWEATDRLDFAGAAATGTTYVETSAADYDAAKTTADGLIGTGIDYVAVQVG
CCCCHHHHCCCCCCCCEECCCCCCCCCEEEEECCCCCCCHHHHCCCCEECCCEEEEEEEC
SDVVIFTDSAGNNGTAEDAVVLVGRTLADIDSSNIV
CEEEEEECCCCCCCCCCCEEEEECCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]