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The map label for this gene is ggt [H]

Identifier: 197103912

GI number: 197103912

Start: 451355

End: 453112

Strand: Reverse

Name: ggt [H]

Synonym: PHZ_c0446

Alternate gene names: 197103912

Gene position: 453112-451355 (Counterclockwise)

Preceding gene: 197103915

Following gene: 197103905

Centisome position: 11.34

GC content: 75.82

Gene sequence:

>1758_bases
GTGATCCGCAAGACGCGTCTGCTGCCCCTCGCCCTTTCCGCCCTCCTCGCCGCCTGCGCCACCCCTGCCGCGCCGCCCGC
GCCGCAGCCGGCGCCTGCGCCCGCCGCCCAGCCCGCCGCCCAGCCTGGGGCCCAGCCTGGCGCCCAGCCCGGCGGCATGG
TCGCCGCGGCCAATCCCCTGGCGGTGGAGGCGGGCCTTCGGGTGCTGCGCGAGGGCGGCTCGGCCGTCGACGCCGCCGTC
GCCGTCCAGGCGGTGCTGGGGCTCGTGGAGCCGCAGAGCTCGGGCCTCGGCGGCGGGGCGTTCCTCACCTACTACGACGC
CGCCACCCGCTCGGTGACCGCCTACGACGGCCGCGAGACCGCCCCGGCCGGCGCGACCCCCGACATGTTCATGGTTCCCG
ACGGCAAGCCGCTCGGCCGCACCGCCGCCATCCTGTCGGGCCGCTCGACCGGCGCGCCGGGCGCGGTCGCCATGCTCGCC
ATGGCCCAGGCCGATCACGGCAGGCTGCCCTGGAACCGCCTGTTCCTCGACGCCGAACGCCTGGCCGACGAGGGCTTCCC
CGCCCCCGGCCGCATGGCCGCGGCGGCGAGCGGCCGCTCGGCCCAGGCGGCCACCGCCGACGCCGCCCGCTACTTCACCA
AGCCCGACGGGACGAAGATCGCCAAGGGCGACATCGTCCGCAATCCGGCCTACGCCGCCACGGTCCGCAAGATCGCCGCC
GAGGGCCCGAAGGCCCTGCTGGAGGGCGAGATCGCCGAGGCCATCGTGGCCAAGGTCCGCGAGGGCCCGCTGCCGGGGAC
CCTGAGCCTCGATGACCTGAAGAGCTACCGGCCGCGAAAGGGCGCCGCCCTCTGCCGTCCCTACCGGGTCTACATCGTCT
GCACGCCGAACGCCCCGTCTGGCGGGCCCGCCGTGCTGCAGGGCCTGGGCCTGCTCGAGCGCACCGACATCGCCGCCCAC
CGCAACGACGTGGAGGGCTGGTACCTGTTCAGCCAGGCGAGCCGCCTGATGTACGCCGACCGCGACCGCTACATCGGCGA
TCCGGCGTTCGTGGACGTGCCGGTCGAGGGGCTGCTGGAGCCCGCCTATCTGGACGCCCGCGCCCGGCTGATCGGCCCCA
CGGCCAGCCCCGAGGCTCCGCAGCCCGGGACGCCCCGCGGCGCCAAGGCCCGCGCGCCCGACCGCACCCTTGAGCCCGCC
GGCACCACCCACTTCGTCGTCGTCGACGGCGCCGGCAACGTGGTCTCGATGACCACCACGGTGGAGAGCATCTTCGGCTC
GGGCCGCATGGTCCACGGCTTCTTCCTGAACAACCAGCTCACCGACTTCTCCTTCTCGCCGGTGGACAGGGACGGCGCGC
CGGCCGCCAACGCGGTCGCGCCGGGCAAGCGCCCGCGCTCGTCCATGGCGCCGGCCATCGTGCTGGACCGCGACCGCCGC
TTCGTGGCCGCCGTCGGCTCGCCGGGCGGCCCGGCCATCCTCGCCTACAACCTGAAGACCCTCGTGGGCGTGCTGGACTG
GAAGCTGCCGGTGCAGGAGGCCATCGACCTGCCCAACCTGATCGCCGCCGGGACCTTCTATGGCGCCGAGGTGGACAAGT
TCGCCCCGGAGCTGCGCGAGGGTCTGGCCGCCCGCGGCGTGAAGCTCACCCCCAGCCCCGGCGCCGAGGGCTCGGGCCTG
CACGGCGTCGAGGTCACGCCCCAGGGCCTGCGCGGCGGCGCCGATCCCCGCCGCGAGGGCGTGGCCCGGGCGCCCTAG

Upstream 100 bases:

>100_bases
ATCTCGGCCATGAGGCGACCTCGCACGCGCCGGCGGCTGTTGTCCACGGCCCGGCGCCGCTATGGTCGCCCGCCATCCCG
CCGCCGGAGTGTTCCCGTCC

Downstream 100 bases:

>100_bases
GGGGCGGATCCGCCCAGGTAGCCGTCGAGTTCGGCGCGCAGCCGCGTCGCCTGGCCGGCGACCATCTGGGCGGCGGCGAA
CATCTCCTGGGCGGCCTGAT

Product: gamma-glutamyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 585; Mature: 585

Protein sequence:

>585_residues
MIRKTRLLPLALSALLAACATPAAPPAPQPAPAPAAQPAAQPGAQPGAQPGGMVAAANPLAVEAGLRVLREGGSAVDAAV
AVQAVLGLVEPQSSGLGGGAFLTYYDAATRSVTAYDGRETAPAGATPDMFMVPDGKPLGRTAAILSGRSTGAPGAVAMLA
MAQADHGRLPWNRLFLDAERLADEGFPAPGRMAAAASGRSAQAATADAARYFTKPDGTKIAKGDIVRNPAYAATVRKIAA
EGPKALLEGEIAEAIVAKVREGPLPGTLSLDDLKSYRPRKGAALCRPYRVYIVCTPNAPSGGPAVLQGLGLLERTDIAAH
RNDVEGWYLFSQASRLMYADRDRYIGDPAFVDVPVEGLLEPAYLDARARLIGPTASPEAPQPGTPRGAKARAPDRTLEPA
GTTHFVVVDGAGNVVSMTTTVESIFGSGRMVHGFFLNNQLTDFSFSPVDRDGAPAANAVAPGKRPRSSMAPAIVLDRDRR
FVAAVGSPGGPAILAYNLKTLVGVLDWKLPVQEAIDLPNLIAAGTFYGAEVDKFAPELREGLAARGVKLTPSPGAEGSGL
HGVEVTPQGLRGGADPRREGVARAP

Sequences:

>Translated_585_residues
MIRKTRLLPLALSALLAACATPAAPPAPQPAPAPAAQPAAQPGAQPGAQPGGMVAAANPLAVEAGLRVLREGGSAVDAAV
AVQAVLGLVEPQSSGLGGGAFLTYYDAATRSVTAYDGRETAPAGATPDMFMVPDGKPLGRTAAILSGRSTGAPGAVAMLA
MAQADHGRLPWNRLFLDAERLADEGFPAPGRMAAAASGRSAQAATADAARYFTKPDGTKIAKGDIVRNPAYAATVRKIAA
EGPKALLEGEIAEAIVAKVREGPLPGTLSLDDLKSYRPRKGAALCRPYRVYIVCTPNAPSGGPAVLQGLGLLERTDIAAH
RNDVEGWYLFSQASRLMYADRDRYIGDPAFVDVPVEGLLEPAYLDARARLIGPTASPEAPQPGTPRGAKARAPDRTLEPA
GTTHFVVVDGAGNVVSMTTTVESIFGSGRMVHGFFLNNQLTDFSFSPVDRDGAPAANAVAPGKRPRSSMAPAIVLDRDRR
FVAAVGSPGGPAILAYNLKTLVGVLDWKLPVQEAIDLPNLIAAGTFYGAEVDKFAPELREGLAARGVKLTPSPGAEGSGL
HGVEVTPQGLRGGADPRREGVARAP
>Mature_585_residues
MIRKTRLLPLALSALLAACATPAAPPAPQPAPAPAAQPAAQPGAQPGAQPGGMVAAANPLAVEAGLRVLREGGSAVDAAV
AVQAVLGLVEPQSSGLGGGAFLTYYDAATRSVTAYDGRETAPAGATPDMFMVPDGKPLGRTAAILSGRSTGAPGAVAMLA
MAQADHGRLPWNRLFLDAERLADEGFPAPGRMAAAASGRSAQAATADAARYFTKPDGTKIAKGDIVRNPAYAATVRKIAA
EGPKALLEGEIAEAIVAKVREGPLPGTLSLDDLKSYRPRKGAALCRPYRVYIVCTPNAPSGGPAVLQGLGLLERTDIAAH
RNDVEGWYLFSQASRLMYADRDRYIGDPAFVDVPVEGLLEPAYLDARARLIGPTASPEAPQPGTPRGAKARAPDRTLEPA
GTTHFVVVDGAGNVVSMTTTVESIFGSGRMVHGFFLNNQLTDFSFSPVDRDGAPAANAVAPGKRPRSSMAPAIVLDRDRR
FVAAVGSPGGPAILAYNLKTLVGVLDWKLPVQEAIDLPNLIAAGTFYGAEVDKFAPELREGLAARGVKLTPSPGAEGSGL
HGVEVTPQGLRGGADPRREGVARAP

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=485, Percent_Identity=31.340206185567, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI73915090, Length=485, Percent_Identity=31.340206185567, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI73915096, Length=485, Percent_Identity=31.340206185567, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI73915094, Length=485, Percent_Identity=31.340206185567, Blast_Score=180, Evalue=3e-45,
Organism=Homo sapiens, GI113429324, Length=484, Percent_Identity=29.5454545454545, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI113429326, Length=490, Percent_Identity=29.1836734693878, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI153266885, Length=525, Percent_Identity=28, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI153266901, Length=526, Percent_Identity=27.1863117870722, Blast_Score=132, Evalue=1e-30,
Organism=Homo sapiens, GI109148539, Length=421, Percent_Identity=29.2161520190024, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI153266907, Length=523, Percent_Identity=25.6214149139579, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI30581157, Length=125, Percent_Identity=36, Blast_Score=67, Evalue=7e-11,
Organism=Homo sapiens, GI30581155, Length=125, Percent_Identity=36, Blast_Score=67, Evalue=7e-11,
Organism=Escherichia coli, GI1789856, Length=593, Percent_Identity=33.220910623946, Blast_Score=243, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI72000294, Length=588, Percent_Identity=27.3809523809524, Blast_Score=171, Evalue=8e-43,
Organism=Caenorhabditis elegans, GI212646519, Length=588, Percent_Identity=27.3809523809524, Blast_Score=171, Evalue=1e-42,
Organism=Caenorhabditis elegans, GI193208247, Length=493, Percent_Identity=30.0202839756592, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI193208245, Length=492, Percent_Identity=30.4878048780488, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17542894, Length=515, Percent_Identity=29.9029126213592, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17506189, Length=493, Percent_Identity=27.1805273833671, Blast_Score=149, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6323330, Length=485, Percent_Identity=26.3917525773196, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18859893, Length=448, Percent_Identity=31.9196428571429, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI45551474, Length=571, Percent_Identity=27.1453590192644, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI161077880, Length=571, Percent_Identity=27.1453590192644, Blast_Score=148, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24642670, Length=571, Percent_Identity=27.1453590192644, Blast_Score=148, Evalue=8e-36,
Organism=Drosophila melanogaster, GI24642666, Length=571, Percent_Identity=27.1453590192644, Blast_Score=148, Evalue=8e-36,
Organism=Drosophila melanogaster, GI161077878, Length=571, Percent_Identity=27.1453590192644, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI161077496, Length=478, Percent_Identity=28.0334728033473, Blast_Score=140, Evalue=2e-33,
Organism=Drosophila melanogaster, GI18859741, Length=493, Percent_Identity=26.9776876267748, Blast_Score=119, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 60281; Mature: 60281

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRKTRLLPLALSALLAACATPAAPPAPQPAPAPAAQPAAQPGAQPGAQPGGMVAAANPL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCH
AVEAGLRVLREGGSAVDAAVAVQAVLGLVEPQSSGLGGGAFLTYYDAATRSVTAYDGRET
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEECCCCCC
APAGATPDMFMVPDGKPLGRTAAILSGRSTGAPGAVAMLAMAQADHGRLPWNRLFLDAER
CCCCCCCCEEECCCCCCCCCHHHEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHEEEHHH
LADEGFPAPGRMAAAASGRSAQAATADAARYFTKPDGTKIAKGDIVRNPAYAATVRKIAA
HHHCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCEEECCCEECCCHHHHHHHHHHH
EGPKALLEGEIAEAIVAKVREGPLPGTLSLDDLKSYRPRKGAALCRPYRVYIVCTPNAPS
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCEEECCEEEEEEECCCCCC
GGPAVLQGLGLLERTDIAAHRNDVEGWYLFSQASRLMYADRDRYIGDPAFVDVPVEGLLE
CCHHHHHHCCCHHHHHHHHHCCCCCEEEEEHHHHHHEEECCCCCCCCCCEEECCHHHCCC
PAYLDARARLIGPTASPEAPQPGTPRGAKARAPDRTLEPAGTTHFVVVDGAGNVVSMTTT
CHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEHHH
VESIFGSGRMVHGFFLNNQLTDFSFSPVDRDGAPAANAVAPGKRPRSSMAPAIVLDRDRR
HHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEECCCE
FVAAVGSPGGPAILAYNLKTLVGVLDWKLPVQEAIDLPNLIAAGTFYGAEVDKFAPELRE
EEEEECCCCCCEEEEECHHHHHHHHHCCCCHHHHCCCCHHHHHCCCCCCCHHHHHHHHHH
GLAARGVKLTPSPGAEGSGLHGVEVTPQGLRGGADPRREGVARAP
HHHHCCEEECCCCCCCCCCCCCEECCCHHCCCCCCHHHCCCCCCC
>Mature Secondary Structure
MIRKTRLLPLALSALLAACATPAAPPAPQPAPAPAAQPAAQPGAQPGAQPGGMVAAANPL
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCH
AVEAGLRVLREGGSAVDAAVAVQAVLGLVEPQSSGLGGGAFLTYYDAATRSVTAYDGRET
HHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEEEECCCCCC
APAGATPDMFMVPDGKPLGRTAAILSGRSTGAPGAVAMLAMAQADHGRLPWNRLFLDAER
CCCCCCCCEEECCCCCCCCCHHHEECCCCCCCCHHHHHHHHHHCCCCCCCHHHHEEEHHH
LADEGFPAPGRMAAAASGRSAQAATADAARYFTKPDGTKIAKGDIVRNPAYAATVRKIAA
HHHCCCCCCCCEEECCCCCCCCHHHHHHHHHCCCCCCCEEECCCEECCCHHHHHHHHHHH
EGPKALLEGEIAEAIVAKVREGPLPGTLSLDDLKSYRPRKGAALCRPYRVYIVCTPNAPS
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCEEECCEEEEEEECCCCCC
GGPAVLQGLGLLERTDIAAHRNDVEGWYLFSQASRLMYADRDRYIGDPAFVDVPVEGLLE
CCHHHHHHCCCHHHHHHHHHCCCCCEEEEEHHHHHHEEECCCCCCCCCCEEECCHHHCCC
PAYLDARARLIGPTASPEAPQPGTPRGAKARAPDRTLEPAGTTHFVVVDGAGNVVSMTTT
CHHHCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCEEEEHHH
VESIFGSGRMVHGFFLNNQLTDFSFSPVDRDGAPAANAVAPGKRPRSSMAPAIVLDRDRR
HHHHHCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCEEEEECCCE
FVAAVGSPGGPAILAYNLKTLVGVLDWKLPVQEAIDLPNLIAAGTFYGAEVDKFAPELRE
EEEEECCCCCCEEEEECHHHHHHHHHCCCCHHHHCCCCHHHHHCCCCCCCHHHHHHHHHH
GLAARGVKLTPSPGAEGSGLHGVEVTPQGLRGGADPRREGVARAP
HHHHCCEEECCCCCCCCCCCCCEECCCHHCCCCCCHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA