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The map label for this gene is tdcB [H]

Identifier: 197103871

GI number: 197103871

Start: 410669

End: 411658

Strand: Reverse

Name: tdcB [H]

Synonym: PHZ_c0405

Alternate gene names: 197103871

Gene position: 411658-410669 (Counterclockwise)

Preceding gene: 197103872

Following gene: 197103865

Centisome position: 10.3

GC content: 72.42

Gene sequence:

>990_bases
ATGAGCGTCACCCCTCCCGGCGTCACCCTGGCCGACATCGAGGCCGCCGCGGCGCGGCTGAAGGGCCATGCGGTCGAGAC
GCCGGTCATCGAGAGCCCGGCGCTCAACGAGCGGGTCGGGCGGCGGGTGCTGATCAAGCCCGAGACCCTGCAGCGGGTCG
GCGCCTTCAAGTTCCGGGGGGCCTACAACCGCCTCGTCCAGCTGGACGCCGAGGAGCGCCGCCGCGGGGTCGTGGCGTTC
TCCTCCGGCAACCACGCCCAGGGCGTCGCCCTGGCGGCGAAGCTGCTGGGGATTCCCGCGGTCATCGTGATGCCGAAGGA
CGCGCCGGCGGTGAAGGTCGCGGCCACGAAGGGCTACGGGGCCGAGGTGCTGTTCTACGACCGCCTCACCGAGAGACGCG
AGGCGATCGCCGCCAAGATCTCCGAGGAGCGCGGCGCCACCGTCGTTCCGGCCTTCGACGACCCGCACGTGGTGGCGGGC
CAGGGGACCGCCGGCCTGGAGCTGGCCCGCCAGGCCCAGGCCGCGGGCGCGACGCTGGGCGTCGTCGTCGCCCCGATCAG
CGGCGGCGGCCTGATCGCGGGCGTTGGCACGGCGGTGAAGGCGCTCTCGCCGCAAACGGCGGTCGTCGGCGTCGAGCCCG
CAGGATTCGACGATGCGAAGGCCTCACTCGAGACGGGCGAGATCGTCGTCCGGAAGGCCACCGGCCGATCCATGTGCGAT
GCGCTGGAATCCCCCTTCGTCGGCGAGATCACCTTCCCGATCATGCAGCGGACGGTGTCGGACATCGTCACCGTCACCGA
CGCCGAGGTGGCGGAGGCGATGCGCTACGCCTTCCAGACGCTGAAGCTGGTGGTGGAGCCCGGCGGCTCGGTCGGCCTCG
CCGCCCTTCTGAGCGGCAAGGTGGCGCCCTCCGGCGACGTCGGCCTCGTCCTGTCGGGCGGCAATGTCGATCCCGACCAG
TTCGCCCGGGTGATCCGCGGCGAGCTCTAG

Upstream 100 bases:

>100_bases
GGGGCCAGCCCGGCGAGCAGGCCACCATGTTCTTCCTCGACCCCTCGGGCAACGCCCTGGAGTTCAAGGCCTTCGCCGAC
GACGCGATGGTCTTCGCCAG

Downstream 100 bases:

>100_bases
CGCCTAGCGGAAGATCTCCAGCGGCGCCCCGGCCTGCGGATCGAACGCCCGCCAGTCCAGCCCGAGCGCCCGCAGCGCCG
TCGCCGCGACCTGATCGGCG

Product: threonine dehydratase

Products: NA

Alternate protein names: Threonine deaminase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MSVTPPGVTLADIEAAAARLKGHAVETPVIESPALNERVGRRVLIKPETLQRVGAFKFRGAYNRLVQLDAEERRRGVVAF
SSGNHAQGVALAAKLLGIPAVIVMPKDAPAVKVAATKGYGAEVLFYDRLTERREAIAAKISEERGATVVPAFDDPHVVAG
QGTAGLELARQAQAAGATLGVVVAPISGGGLIAGVGTAVKALSPQTAVVGVEPAGFDDAKASLETGEIVVRKATGRSMCD
ALESPFVGEITFPIMQRTVSDIVTVTDAEVAEAMRYAFQTLKLVVEPGGSVGLAALLSGKVAPSGDVGLVLSGGNVDPDQ
FARVIRGEL

Sequences:

>Translated_329_residues
MSVTPPGVTLADIEAAAARLKGHAVETPVIESPALNERVGRRVLIKPETLQRVGAFKFRGAYNRLVQLDAEERRRGVVAF
SSGNHAQGVALAAKLLGIPAVIVMPKDAPAVKVAATKGYGAEVLFYDRLTERREAIAAKISEERGATVVPAFDDPHVVAG
QGTAGLELARQAQAAGATLGVVVAPISGGGLIAGVGTAVKALSPQTAVVGVEPAGFDDAKASLETGEIVVRKATGRSMCD
ALESPFVGEITFPIMQRTVSDIVTVTDAEVAEAMRYAFQTLKLVVEPGGSVGLAALLSGKVAPSGDVGLVLSGGNVDPDQ
FARVIRGEL
>Mature_328_residues
SVTPPGVTLADIEAAAARLKGHAVETPVIESPALNERVGRRVLIKPETLQRVGAFKFRGAYNRLVQLDAEERRRGVVAFS
SGNHAQGVALAAKLLGIPAVIVMPKDAPAVKVAATKGYGAEVLFYDRLTERREAIAAKISEERGATVVPAFDDPHVVAGQ
GTAGLELARQAQAAGATLGVVVAPISGGGLIAGVGTAVKALSPQTAVVGVEPAGFDDAKASLETGEIVVRKATGRSMCDA
LESPFVGEITFPIMQRTVSDIVTVTDAEVAEAMRYAFQTLKLVVEPGGSVGLAALLSGKVAPSGDVGLVLSGGNVDPDQF
ARVIRGEL

Specific function: Acts on both serine and threonine, and properly considered as a hydroxy amino acid deaminase [H]

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serine/threonine dehydratase family [H]

Homologues:

Organism=Homo sapiens, GI11345492, Length=317, Percent_Identity=39.1167192429022, Blast_Score=212, Evalue=4e-55,
Organism=Homo sapiens, GI19923959, Length=285, Percent_Identity=27.3684210526316, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1789505, Length=320, Percent_Identity=39.0625, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1790207, Length=295, Percent_Identity=37.6271186440678, Blast_Score=157, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17508781, Length=315, Percent_Identity=30.4761904761905, Blast_Score=147, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI71991565, Length=324, Percent_Identity=33.0246913580247, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17537387, Length=325, Percent_Identity=34.7692307692308, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6322631, Length=321, Percent_Identity=44.5482866043614, Blast_Score=261, Evalue=8e-71,
Organism=Saccharomyces cerevisiae, GI6320930, Length=303, Percent_Identity=37.2937293729373, Blast_Score=178, Evalue=9e-46,
Organism=Saccharomyces cerevisiae, GI6319788, Length=279, Percent_Identity=25.8064516129032, Blast_Score=68, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355833, Length=328, Percent_Identity=32.6219512195122, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24645328, Length=229, Percent_Identity=31.4410480349345, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR005789 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.19 [H]

Molecular weight: Translated: 33904; Mature: 33773

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVTPPGVTLADIEAAAARLKGHAVETPVIESPALNERVGRRVLIKPETLQRVGAFKFRG
CCCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCEEEECCHHHHHHCCHHCCC
AYNRLVQLDAEERRRGVVAFSSGNHAQGVALAAKLLGIPAVIVMPKDAPAVKVAATKGYG
HHHHHEECCHHHHCCCEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCC
AEVLFYDRLTERREAIAAKISEERGATVVPAFDDPHVVAGQGTAGLELARQAQAAGATLG
CEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHCCCEEE
VVVAPISGGGLIAGVGTAVKALSPQTAVVGVEPAGFDDAKASLETGEIVVRKATGRSMCD
EEEEEECCCCEEEEHHHHHHHCCCCEEEEECCCCCCCCHHCCCCCCEEEEEECCCHHHHH
ALESPFVGEITFPIMQRTVSDIVTVTDAEVAEAMRYAFQTLKLVVEPGGSVGLAALLSGK
HHCCCCCCEEHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHEEEECCCCCEEHHHHHCCC
VAPSGDVGLVLSGGNVDPDQFARVIRGEL
CCCCCCEEEEEECCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SVTPPGVTLADIEAAAARLKGHAVETPVIESPALNERVGRRVLIKPETLQRVGAFKFRG
CCCCCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCCEEEECCHHHHHHCCHHCCC
AYNRLVQLDAEERRRGVVAFSSGNHAQGVALAAKLLGIPAVIVMPKDAPAVKVAATKGYG
HHHHHEECCHHHHCCCEEEECCCCCCHHHHHHHHHHCCCEEEEECCCCCEEEEEEECCCC
AEVLFYDRLTERREAIAAKISEERGATVVPAFDDPHVVAGQGTAGLELARQAQAAGATLG
CEEEEHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCHHHHHHHHHHHCCCEEE
VVVAPISGGGLIAGVGTAVKALSPQTAVVGVEPAGFDDAKASLETGEIVVRKATGRSMCD
EEEEEECCCCEEEEHHHHHHHCCCCEEEEECCCCCCCCHHCCCCCCEEEEEECCCHHHHH
ALESPFVGEITFPIMQRTVSDIVTVTDAEVAEAMRYAFQTLKLVVEPGGSVGLAALLSGK
HHCCCCCCEEHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHEEEECCCCCEEHHHHHCCC
VAPSGDVGLVLSGGNVDPDQFARVIRGEL
CCCCCCEEEEEECCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA