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The map label for this gene is cycY [H]

Identifier: 197103601

GI number: 197103601

Start: 126745

End: 127260

Strand: Reverse

Name: cycY [H]

Synonym: PHZ_c0135

Alternate gene names: 197103601

Gene position: 127260-126745 (Counterclockwise)

Preceding gene: 197103602

Following gene: 197103600

Centisome position: 3.18

GC content: 71.32

Gene sequence:

>516_bases
ATGAGCCGCTGGCTGGCCTGGATCCCGCTCGCCGCCCTGGTCGCCCTGGGGCTGCTGTTCGGCCTCTACGCCCTCAACCG
CAATCCGCAGATCCAGCCGCAGGCGCTGGTGGGCAAACCCGTACCGACGGTCAGCCTGCCGACGCTCGCCGAGGGCCAGC
CGGTTTCCCTGCGCGAGATGGCGTCGGAAGGACCGATGATCGTCAACTTCTTCGCCTCCTGGTGCGCCCCCTGCGAGATC
GAGCACCCGGTGCTGATGGGCCTGAAGGGCCAGCCGGTGCGGGTGGTCGGCATCGCCTACAAGGACGCGCCCCAGAACAG
CCAGGCCTTCCTGGACCGCCTCGGCGATCCCTACGCGGAGGTGCTGGTGGACCGCGACGGGCGCGCGGGCGTCGAGTTCG
GCGTCACCGGCGTGCCCGAGACCTATGTCGTGGGCCGCGACGGCATGATCCTGGCCAAGCACACCGGCCCCCTCACCGAG
GCCGACGCCCGGAGGCTTGCGGCCCAGGCCCGCTGA

Upstream 100 bases:

>100_bases
CCGCCTTCGTCGTGACTGGCCTGGCCTTCGCCGGCATGGTGTGGGAGGCGCTGGCCCACGCCCGCCGCTGGAAGCGCCGC
TACGAGGAGCGCGCCCGCAA

Downstream 100 bases:

>100_bases
GAAGGGCGCGCTGATGAGGTGCGCGGCCGGGCGCGTTAACCACTTCTTGAGGCGGACGCGGGCACCCAGGGAGCGTCCCT
GTTAACCATGTCCGGCCTTC

Product: thiol:disulfide interchange protein CycY

Products: NA

Alternate protein names: Cytochrome c biogenesis protein CycY [H]

Number of amino acids: Translated: 171; Mature: 170

Protein sequence:

>171_residues
MSRWLAWIPLAALVALGLLFGLYALNRNPQIQPQALVGKPVPTVSLPTLAEGQPVSLREMASEGPMIVNFFASWCAPCEI
EHPVLMGLKGQPVRVVGIAYKDAPQNSQAFLDRLGDPYAEVLVDRDGRAGVEFGVTGVPETYVVGRDGMILAKHTGPLTE
ADARRLAAQAR

Sequences:

>Translated_171_residues
MSRWLAWIPLAALVALGLLFGLYALNRNPQIQPQALVGKPVPTVSLPTLAEGQPVSLREMASEGPMIVNFFASWCAPCEI
EHPVLMGLKGQPVRVVGIAYKDAPQNSQAFLDRLGDPYAEVLVDRDGRAGVEFGVTGVPETYVVGRDGMILAKHTGPLTE
ADARRLAAQAR
>Mature_170_residues
SRWLAWIPLAALVALGLLFGLYALNRNPQIQPQALVGKPVPTVSLPTLAEGQPVSLREMASEGPMIVNFFASWCAPCEIE
HPVLMGLKGQPVRVVGIAYKDAPQNSQAFLDRLGDPYAEVLVDRDGRAGVEFGVTGVPETYVVGRDGMILAKHTGPLTEA
DARRLAAQAR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur [

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=165, Percent_Identity=38.1818181818182, Blast_Score=108, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 18401; Mature: 18269

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRWLAWIPLAALVALGLLFGLYALNRNPQIQPQALVGKPVPTVSLPTLAEGQPVSLREM
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHH
ASEGPMIVNFFASWCAPCEIEHPVLMGLKGQPVRVVGIAYKDAPQNSQAFLDRLGDPYAE
HCCCCEEEEEHHHHCCCCCCCCCEEECCCCCCEEEEEEEECCCCCCHHHHHHHHCCCHHH
VLVDRDGRAGVEFGVTGVPETYVVGRDGMILAKHTGPLTEADARRLAAQAR
HEECCCCCCCCEECCCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
SRWLAWIPLAALVALGLLFGLYALNRNPQIQPQALVGKPVPTVSLPTLAEGQPVSLREM
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCHHHHH
ASEGPMIVNFFASWCAPCEIEHPVLMGLKGQPVRVVGIAYKDAPQNSQAFLDRLGDPYAE
HCCCCEEEEEHHHHCCCCCCCCCEEECCCCCCEEEEEEEECCCCCCHHHHHHHHCCCHHH
VLVDRDGRAGVEFGVTGVPETYVVGRDGMILAKHTGPLTEADARRLAAQAR
HEECCCCCCCCEECCCCCCCEEEECCCCEEEEECCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]