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The map label for this gene is mocR [H]

Identifier: 197103589

GI number: 197103589

Start: 113975

End: 115432

Strand: Direct

Name: mocR [H]

Synonym: PHZ_c0123

Alternate gene names: 197103589

Gene position: 113975-115432 (Clockwise)

Preceding gene: 197103587

Following gene: 197103590

Centisome position: 2.85

GC content: 76.61

Gene sequence:

>1458_bases
ATGAGCTGGGCCGACATCTATCCGTGGGAGGCGCCGGGGCCCGGCGGGCCCGTGATCCGGCAGGTCTACGAGCAGGTGCG
CGGCGCCATCCACCAGGGGGCGCTGAAGCCGGGCGGGCGGCTGCCCTCCAGCCGCGATCTCGCCGCGCGGCTGGGCGTGG
CGCGGGCCTCGGTGGTGGCCGCCTACGACCTGCTGCTGGCCGAAGGCTACGCCGAAGGTCGGCCGGGCTCGGGCACCTAC
GTCTGCGGCGACCTCTCCGGGGTGCTGGAGCTGAAGGCCCCGTCCGCCGCGCCCGCCGCCCCGCCGCCGCTGACGCCGCC
GCGCGTCGCGTCGCTGGCCGCCCTGCCCCTGCCCGGACCCGACGAGCCCCGCCTGTTCTCCAACGGCCGAACGCTGATGG
ACGCCCGCGCCCTGGACGCCTGGGCGAAGGCAACGCGCCGGGCCCTCCGGACCCTGGACCACGTCCACTTCGGCTATTCA
GACCCGGCGGGAGAGCCCCGCCTGCGGGCCGCGGTCGCCGACTACCTGCGCGCGGCGCGGGGCGTGGTCTGCGACCCCGA
CCAGGTGATTGTCACCTCGGGCGCCCAGCACGCTGTGGACATCGCCGTGCGCGTGCTGCTGCAGCCCGGCGATCCGGTCT
GGATGGAGGACCCCGGCTACCAGCCGACCTGGCACGCCCTGACCGCCGCCGGGGCGGTGGTGCATGCGGTGCCCGTCGAC
CGGGCGGGGCTGGACGTCGCGGCGGGGATGGCCGCGGAGCCGCGGGCCCGGCTCGCCTTCGTCACCCCCTCGCACCAGTA
CCCGCTGGGCGTGACGCTCTCGATGGGCCGGCGGCTGGAGCTGCTGGCCTGGGCCCGCGAGGCCGGGGCCTGGATCGTGG
AGGACGACTACTCGGCCGAGTTCCGCTACTCGGGCCCGCCGCTGGCCGCGCTGCAGGGCCTGGATGGCGGCGAGCGGGTG
ATCTACGTCGGCACGCTGAACAAGGCGCTCTTCCCGGGCCTGCGGCTCGGCTACATGGTCGCCCCGCGGCCGCTGGCCGC
CGCGCTGACCGCCGCGCGCCAGCTCACCGACCGGCAGCCCCCGACGCTGACCCAGGCCGTCGTGCTCGACTTCATGGAGA
GCGGCCAGTTCGCCGCCCACATCCGCCGCCGCCGGATCGCATACAAGGTCCAGCGCGACGCGCTCGCGCAGGCGCTGCGG
GACGCGTTGGGGGACCGGGTCGAGATCGGCCTGCCCGACCAGGGGCTGCACCTGACCGCGTTCCTGAACGGCGGGCTCGA
CGACGTGGCGGCCGAGCGCGCGGCGGCCGGGCGGGGGATCATCGCCCGGGCGATCAGTCCGCTGTACCGCCGCGCGCCGC
CCCGCGCCGGCCTGATGCTCGGCTTCTCGGGCTTTCCGGCGCGCGGCATGGCGGCCGGCGTCGCGCGGCTGGCCGCGGCC
CTGGACTCGCTGGGATGA

Upstream 100 bases:

>100_bases
ATCGGCGGAACTCCGTTACGTGGGTTCCGCAGCTAGAGGATATGTGGTCTAGCATGTAGGTCCAATCGGCGACGTCGCCG
CAGACCACTTCGGGGCGAGC

Downstream 100 bases:

>100_bases
AGAGGAAGGCGCCCGGGGGATGCTTGGGGGGAGGTAGGGAAGCACCCCCCGGGCGGGGCTGAAGTTGGTGTGCGTGTCCA
GACTTCAGGAGAGCGCCGGG

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MSWADIYPWEAPGPGGPVIRQVYEQVRGAIHQGALKPGGRLPSSRDLAARLGVARASVVAAYDLLLAEGYAEGRPGSGTY
VCGDLSGVLELKAPSAAPAAPPPLTPPRVASLAALPLPGPDEPRLFSNGRTLMDARALDAWAKATRRALRTLDHVHFGYS
DPAGEPRLRAAVADYLRAARGVVCDPDQVIVTSGAQHAVDIAVRVLLQPGDPVWMEDPGYQPTWHALTAAGAVVHAVPVD
RAGLDVAAGMAAEPRARLAFVTPSHQYPLGVTLSMGRRLELLAWAREAGAWIVEDDYSAEFRYSGPPLAALQGLDGGERV
IYVGTLNKALFPGLRLGYMVAPRPLAAALTAARQLTDRQPPTLTQAVVLDFMESGQFAAHIRRRRIAYKVQRDALAQALR
DALGDRVEIGLPDQGLHLTAFLNGGLDDVAAERAAAGRGIIARAISPLYRRAPPRAGLMLGFSGFPARGMAAGVARLAAA
LDSLG

Sequences:

>Translated_485_residues
MSWADIYPWEAPGPGGPVIRQVYEQVRGAIHQGALKPGGRLPSSRDLAARLGVARASVVAAYDLLLAEGYAEGRPGSGTY
VCGDLSGVLELKAPSAAPAAPPPLTPPRVASLAALPLPGPDEPRLFSNGRTLMDARALDAWAKATRRALRTLDHVHFGYS
DPAGEPRLRAAVADYLRAARGVVCDPDQVIVTSGAQHAVDIAVRVLLQPGDPVWMEDPGYQPTWHALTAAGAVVHAVPVD
RAGLDVAAGMAAEPRARLAFVTPSHQYPLGVTLSMGRRLELLAWAREAGAWIVEDDYSAEFRYSGPPLAALQGLDGGERV
IYVGTLNKALFPGLRLGYMVAPRPLAAALTAARQLTDRQPPTLTQAVVLDFMESGQFAAHIRRRRIAYKVQRDALAQALR
DALGDRVEIGLPDQGLHLTAFLNGGLDDVAAERAAAGRGIIARAISPLYRRAPPRAGLMLGFSGFPARGMAAGVARLAAA
LDSLG
>Mature_484_residues
SWADIYPWEAPGPGGPVIRQVYEQVRGAIHQGALKPGGRLPSSRDLAARLGVARASVVAAYDLLLAEGYAEGRPGSGTYV
CGDLSGVLELKAPSAAPAAPPPLTPPRVASLAALPLPGPDEPRLFSNGRTLMDARALDAWAKATRRALRTLDHVHFGYSD
PAGEPRLRAAVADYLRAARGVVCDPDQVIVTSGAQHAVDIAVRVLLQPGDPVWMEDPGYQPTWHALTAAGAVVHAVPVDR
AGLDVAAGMAAEPRARLAFVTPSHQYPLGVTLSMGRRLELLAWAREAGAWIVEDDYSAEFRYSGPPLAALQGLDGGERVI
YVGTLNKALFPGLRLGYMVAPRPLAAALTAARQLTDRQPPTLTQAVVLDFMESGQFAAHIRRRRIAYKVQRDALAQALRD
ALGDRVEIGLPDQGLHLTAFLNGGLDDVAAERAAAGRGIIARAISPLYRRAPPRAGLMLGFSGFPARGMAAGVARLAAAL
DSLG

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=363, Percent_Identity=25.8953168044077, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI33469970, Length=363, Percent_Identity=25.8953168044077, Blast_Score=96, Evalue=7e-20,
Organism=Escherichia coli, GI1787710, Length=426, Percent_Identity=28.4037558685446, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1790797, Length=420, Percent_Identity=25.7142857142857, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788722, Length=254, Percent_Identity=26.7716535433071, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 51265; Mature: 51134

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: PS50949 HTH_GNTR ; PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWADIYPWEAPGPGGPVIRQVYEQVRGAIHQGALKPGGRLPSSRDLAARLGVARASVVA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AYDLLLAEGYAEGRPGSGTYVCGDLSGVLELKAPSAAPAAPPPLTPPRVASLAALPLPGP
HHHHHHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHEEECCCCCC
DEPRLFSNGRTLMDARALDAWAKATRRALRTLDHVHFGYSDPAGEPRLRAAVADYLRAAR
CCCCEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
GVVCDPDQVIVTSGAQHAVDIAVRVLLQPGDPVWMEDPGYQPTWHALTAAGAVVHAVPVD
CCCCCCCCEEEECCCHHHHHHHHHEEECCCCCCEECCCCCCCHHHHHHHHCCEEEECCCC
RAGLDVAAGMAAEPRARLAFVTPSHQYPLGVTLSMGRRLELLAWAREAGAWIVEDDYSAE
CCCCHHHCCCCCCCCCEEEEECCCCCCCCEEEECCCCCCHHHHHHHHCCCEEEECCCCCE
FRYSGPPLAALQGLDGGERVIYVGTLNKALFPGLRLGYMVAPRPLAAALTAARQLTDRQP
EEECCCCHHHHCCCCCCCEEEEEEECCHHHCCCCCCCEEECCCHHHHHHHHHHHHHCCCC
PTLTQAVVLDFMESGQFAAHIRRRRIAYKVQRDALAQALRDALGDRVEIGLPDQGLHLTA
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEE
FLNGGLDDVAAERAAAGRGIIARAISPLYRRAPPRAGLMLGFSGFPARGMAAGVARLAAA
EECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
LDSLG
HHHCC
>Mature Secondary Structure 
SWADIYPWEAPGPGGPVIRQVYEQVRGAIHQGALKPGGRLPSSRDLAARLGVARASVVA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AYDLLLAEGYAEGRPGSGTYVCGDLSGVLELKAPSAAPAAPPPLTPPRVASLAALPLPGP
HHHHHHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCCCCCCCCCCCHHHHEEECCCCCC
DEPRLFSNGRTLMDARALDAWAKATRRALRTLDHVHFGYSDPAGEPRLRAAVADYLRAAR
CCCCEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
GVVCDPDQVIVTSGAQHAVDIAVRVLLQPGDPVWMEDPGYQPTWHALTAAGAVVHAVPVD
CCCCCCCCEEEECCCHHHHHHHHHEEECCCCCCEECCCCCCCHHHHHHHHCCEEEECCCC
RAGLDVAAGMAAEPRARLAFVTPSHQYPLGVTLSMGRRLELLAWAREAGAWIVEDDYSAE
CCCCHHHCCCCCCCCCEEEEECCCCCCCCEEEECCCCCCHHHHHHHHCCCEEEECCCCCE
FRYSGPPLAALQGLDGGERVIYVGTLNKALFPGLRLGYMVAPRPLAAALTAARQLTDRQP
EEECCCCHHHHCCCCCCCEEEEEEECCHHHCCCCCCCEEECCCHHHHHHHHHHHHHCCCC
PTLTQAVVLDFMESGQFAAHIRRRRIAYKVQRDALAQALRDALGDRVEIGLPDQGLHLTA
CHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEE
FLNGGLDDVAAERAAAGRGIIARAISPLYRRAPPRAGLMLGFSGFPARGMAAGVARLAAA
EECCCHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHH
LDSLG
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]