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The map label for this gene is chvG [H]

Identifier: 197103550

GI number: 197103550

Start: 80169

End: 81761

Strand: Direct

Name: chvG [H]

Synonym: PHZ_c0084

Alternate gene names: 197103550

Gene position: 80169-81761 (Clockwise)

Preceding gene: 197103549

Following gene: 197103551

Centisome position: 2.01

GC content: 71.88

Gene sequence:

>1593_bases
ATGGCGTCGGCTACCGCTACCGGGAAACCTGAGCGGCCGGCCCGGGCTTCGAAGTTCCGCTGGCTGCCGGGCTCCAAGCT
CGGCCGGCTGATCGTCGCCCTGAACCTGCTGGGCCTCGCGGTTCTCGTGGGGGGCGCCCTGGTGCTGAACGAGCTGCGCC
AGGGCCTCGTCAACGCGCGCATCGACAGCCTCAGCACCCAGGGCGCGCTGATCGCCGACATCATCAACCGGGCGGCCACG
GTGGGCGAGCCCGAGCCCGAGATGGATACGGCGCTCGCCGCCGACATCATGCAGACCTTCAAGAGCCCGACCACCCAGCG
GGCGCGCCTGTACGACCGCGAGGGGCGGCTGGTGGCCGACACCGACCTCCTCGCCGACCGGGTGGAGTGGAAGGTGCTGC
CGCCCGCCCGGGCCCGGGAGGAGCGCGGCGTCCACCTCGACCTCATGCCGCACAAGCCGAAGGCCACCGCGGAGGAGGCG
CAGCAGCAGCTCGCCTTCGAGGTGGGCGAGGCGCTGAAGGGTCGCCAGTGGGCCGGGATGCGCCGCAGCGCCGACGGCGA
GCGGGTGGTCTCGGTCTCGATCCCTATCCGCCACGTGAAGGCCGTGCTGGGGGTGATCACCCTGGAAGCCAGCGACGTCG
ACGAGATCATCGCCGGCGAGCGGGCCGCGCTGATCCCCTTCATCCTGATCGCGGTGGCGGTGAACCTCGCCTCTATCCTG
CTGCTGAACAGCCTGGTCGCCCAGCCTGTGCGCCGGCTCGCCCGCGCGGCCGACCGGGTGCGCCAGGCCCGGGCCCGGGC
TATCTCGCTGCCGGACCTCGCCAAGCGGGACGACGAGATCGGTGACCTGACCCGCAGCCTGGAGGACATGACCCACTCGC
TCTCCGAGCGGATGGACGCCATCGAGGCTTTCGCGGCGGACGTGGCCCACGAGATCCGCAACCCGCTGACCTCGATCCGC
TCGGCCGTGGAGACCCTCGACCTCGTGAAGGAGCCCGCCTCCCGCGAGCGGCTGATGGGGGTGGTGAAGAACGACGTCCA
GCGGCTGGACCGGCTGGTCACCGACATCTCCAACGCCTCGCGGCTGGACGCCGAGCTCTCGCGCGACCAGCCGAAGCTTG
TGGACGTCGGCCGCCTGCTGTCCGACATCGTCCGCCTCTACCAGGCCACCGCCAAGACGGGCGACGTGCGCGTCCGCCTC
GAGATCGCCCCCGGCGCCGAGCCGGTCCGGGTGATGGGGCGCGAGGGCCCGCTGGGGCAGATCTTCCGCAACCTCATCGA
CAACGCCCGCTCGTTCAGCCCCCCGGGCGACGTGGTCACCGTCGCCCTCGGCCGCGGGCACGGCCGGGTGGTGGCCACCG
TCTCGGACAACGGCCCGGGCATTCCCCCGGAGAACCTGGAGACGATCTTTGAGCGGTTCTACACCTCGCGGCCCAAGGGC
GCGGCGTTCGGCGGCAATTCGGGCCTTGGACTGTCGATCGCGCGGCAGATCGCCGAGGCGCACGGCGGCACCGTGCAGGC
GCAGAACCGGACCGCCGACGGCGAGGTGCTGGGCGCCGTCTTCACGCTGATCCTTCCGGACTCCGAGCCGTGA

Upstream 100 bases:

>100_bases
CAGGTCTATGTCGACGACCGCACGATCGACAGCCACATCAAGCGCATGCGCAAGAAGTTCCGCGAGGTCGACCCCGATTT
CGACGCGATCGAAACCCTCT

Downstream 100 bases:

>100_bases
TCCGCCACGCCGGCCTCGTGGCGCAGCGGATCGGCGGCCGCTGGCTGGGCGTGCTGATCGAGGGGCCGTCCGGCGCGGGC
AAGAGCGATCTCGCCCTCCG

Product: sensor histidine kinase

Products: NA

Alternate protein names: Histidine kinase sensory protein ExoS [H]

Number of amino acids: Translated: 530; Mature: 529

Protein sequence:

>530_residues
MASATATGKPERPARASKFRWLPGSKLGRLIVALNLLGLAVLVGGALVLNELRQGLVNARIDSLSTQGALIADIINRAAT
VGEPEPEMDTALAADIMQTFKSPTTQRARLYDREGRLVADTDLLADRVEWKVLPPARAREERGVHLDLMPHKPKATAEEA
QQQLAFEVGEALKGRQWAGMRRSADGERVVSVSIPIRHVKAVLGVITLEASDVDEIIAGERAALIPFILIAVAVNLASIL
LLNSLVAQPVRRLARAADRVRQARARAISLPDLAKRDDEIGDLTRSLEDMTHSLSERMDAIEAFAADVAHEIRNPLTSIR
SAVETLDLVKEPASRERLMGVVKNDVQRLDRLVTDISNASRLDAELSRDQPKLVDVGRLLSDIVRLYQATAKTGDVRVRL
EIAPGAEPVRVMGREGPLGQIFRNLIDNARSFSPPGDVVTVALGRGHGRVVATVSDNGPGIPPENLETIFERFYTSRPKG
AAFGGNSGLGLSIARQIAEAHGGTVQAQNRTADGEVLGAVFTLILPDSEP

Sequences:

>Translated_530_residues
MASATATGKPERPARASKFRWLPGSKLGRLIVALNLLGLAVLVGGALVLNELRQGLVNARIDSLSTQGALIADIINRAAT
VGEPEPEMDTALAADIMQTFKSPTTQRARLYDREGRLVADTDLLADRVEWKVLPPARAREERGVHLDLMPHKPKATAEEA
QQQLAFEVGEALKGRQWAGMRRSADGERVVSVSIPIRHVKAVLGVITLEASDVDEIIAGERAALIPFILIAVAVNLASIL
LLNSLVAQPVRRLARAADRVRQARARAISLPDLAKRDDEIGDLTRSLEDMTHSLSERMDAIEAFAADVAHEIRNPLTSIR
SAVETLDLVKEPASRERLMGVVKNDVQRLDRLVTDISNASRLDAELSRDQPKLVDVGRLLSDIVRLYQATAKTGDVRVRL
EIAPGAEPVRVMGREGPLGQIFRNLIDNARSFSPPGDVVTVALGRGHGRVVATVSDNGPGIPPENLETIFERFYTSRPKG
AAFGGNSGLGLSIARQIAEAHGGTVQAQNRTADGEVLGAVFTLILPDSEP
>Mature_529_residues
ASATATGKPERPARASKFRWLPGSKLGRLIVALNLLGLAVLVGGALVLNELRQGLVNARIDSLSTQGALIADIINRAATV
GEPEPEMDTALAADIMQTFKSPTTQRARLYDREGRLVADTDLLADRVEWKVLPPARAREERGVHLDLMPHKPKATAEEAQ
QQLAFEVGEALKGRQWAGMRRSADGERVVSVSIPIRHVKAVLGVITLEASDVDEIIAGERAALIPFILIAVAVNLASILL
LNSLVAQPVRRLARAADRVRQARARAISLPDLAKRDDEIGDLTRSLEDMTHSLSERMDAIEAFAADVAHEIRNPLTSIRS
AVETLDLVKEPASRERLMGVVKNDVQRLDRLVTDISNASRLDAELSRDQPKLVDVGRLLSDIVRLYQATAKTGDVRVRLE
IAPGAEPVRVMGREGPLGQIFRNLIDNARSFSPPGDVVTVALGRGHGRVVATVSDNGPGIPPENLETIFERFYTSRPKGA
AFGGNSGLGLSIARQIAEAHGGTVQAQNRTADGEVLGAVFTLILPDSEP

Specific function: Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Activates ChvI by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=302, Percent_Identity=33.4437086092715, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1790861, Length=356, Percent_Identity=29.4943820224719, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=29.0748898678414, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=27.1551724137931, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786783, Length=287, Percent_Identity=26.4808362369338, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=30.8641975308642, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790346, Length=268, Percent_Identity=25.7462686567164, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=27.2727272727273, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1787894, Length=254, Percent_Identity=30.3149606299213, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1790551, Length=291, Percent_Identity=30.2405498281787, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=29.0598290598291, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI145693157, Length=347, Percent_Identity=23.0547550432277, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=263, Percent_Identity=26.615969581749, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=26.6666666666667, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI87082128, Length=279, Percent_Identity=27.5985663082437, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081816, Length=232, Percent_Identity=31.4655172413793, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI1787374, Length=350, Percent_Identity=22.8571428571429, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1789808, Length=384, Percent_Identity=23.9583333333333, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1789149, Length=364, Percent_Identity=21.7032967032967, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57181; Mature: 57050

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASATATGKPERPARASKFRWLPGSKLGRLIVALNLLGLAVLVGGALVLNELRQGLVNAR
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDSLSTQGALIADIINRAATVGEPEPEMDTALAADIMQTFKSPTTQRARLYDREGRLVAD
HHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEC
TDLLADRVEWKVLPPARAREERGVHLDLMPHKPKATAEEAQQQLAFEVGEALKGRQWAGM
HHHHHHHHCEEECCCHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
RRSADGERVVSVSIPIRHVKAVLGVITLEASDVDEIIAGERAALIPFILIAVAVNLASIL
CCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LLNSLVAQPVRRLARAADRVRQARARAISLPDLAKRDDEIGDLTRSLEDMTHSLSERMDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IEAFAADVAHEIRNPLTSIRSAVETLDLVKEPASRERLMGVVKNDVQRLDRLVTDISNAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RLDAELSRDQPKLVDVGRLLSDIVRLYQATAKTGDVRVRLEIAPGAEPVRVMGREGPLGQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCCCHHH
IFRNLIDNARSFSPPGDVVTVALGRGHGRVVATVSDNGPGIPPENLETIFERFYTSRPKG
HHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCC
AAFGGNSGLGLSIARQIAEAHGGTVQAQNRTADGEVLGAVFTLILPDSEP
CCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
ASATATGKPERPARASKFRWLPGSKLGRLIVALNLLGLAVLVGGALVLNELRQGLVNAR
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IDSLSTQGALIADIINRAATVGEPEPEMDTALAADIMQTFKSPTTQRARLYDREGRLVAD
HHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCEEEC
TDLLADRVEWKVLPPARAREERGVHLDLMPHKPKATAEEAQQQLAFEVGEALKGRQWAGM
HHHHHHHHCEEECCCHHHHHHCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
RRSADGERVVSVSIPIRHVKAVLGVITLEASDVDEIIAGERAALIPFILIAVAVNLASIL
CCCCCCCEEEEEECCHHHHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LLNSLVAQPVRRLARAADRVRQARARAISLPDLAKRDDEIGDLTRSLEDMTHSLSERMDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
IEAFAADVAHEIRNPLTSIRSAVETLDLVKEPASRERLMGVVKNDVQRLDRLVTDISNAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RLDAELSRDQPKLVDVGRLLSDIVRLYQATAKTGDVRVRLEIAPGAEPVRVMGREGPLGQ
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHCCCCCCHHH
IFRNLIDNARSFSPPGDVVTVALGRGHGRVVATVSDNGPGIPPENLETIFERFYTSRPKG
HHHHHHHHHCCCCCCCCEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHHHHHHCCCCCC
AAFGGNSGLGLSIARQIAEAHGGTVQAQNRTADGEVLGAVFTLILPDSEP
CCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9422587; 11481430; 7559334 [H]