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The map label for this gene is dnaQ [H]

Identifier: 197103471

GI number: 197103471

Start: 2989

End: 3693

Strand: Direct

Name: dnaQ [H]

Synonym: PHZ_c0005

Alternate gene names: 197103471

Gene position: 2989-3693 (Clockwise)

Preceding gene: 197103470

Following gene: 197103473

Centisome position: 0.07

GC content: 69.5

Gene sequence:

>705_bases
ATGGCGCGCGAAATCGTCCTCGACACCGAGACCACGGGCTTCGACCCGCTCACCGGCGACCGGCTGGTGGAAATCGCCTG
CCTTGAGATCGAGGATTTCATCCCGACCGGGCGGCACTTCCACGCCTACATCGATCCCTGCCGGGACATGCCGGCCGAGG
CCGAGAAGGTGCACGGCCTCTCCACCGCCTTCCTGCGCGGCAAGCCGAAGTTCGAGGCGCCCGAGATCGTCGAGGCGTTC
CTGGACTTCGTGGCCGATGCGCCGATCGTCGCCCACAATGCGGCCTTCGACCGGGCCTTCGTGAACTACGAGCTGGGCCT
GTGCAGCCGGGCCGAGCTGCCCGACCACCGCTGGATCGACACCCTGGCGCTCGCCAAGCAGCGCTTCCCGGGGATGCACA
ACTCGCTGGACGCGCTCTGCAAGCGCTTCAAGATCTCGCTGGCGGAGCGCGAGAAGCACGGGGCGCTGATCGACACCAAG
CTGCTGGCGGCGGTCTATCTCGAGCTGCGCGGCGGCCGCGAACGGCGGCTGGAGCTGACCTCGTCCGCGGCGGTCAGCGC
GGTGCACGCGGCGACGCGCAACAGCTACGGCGCGCGACCGAGGCCGCTGGCGCCCCTCTCCAGCGACGAGGAGCGCGCGG
TCCACGCCGCGTTCATCCGCGAGGTGGTCAAGAGCGAGGAGCTCTGGGGCAAGTTCGGGCTGTAG

Upstream 100 bases:

>100_bases
CGCCGCCCTGCGGGCCGGGACGGACGGAGGGCGCGGCGACTAGCCGCCTGCGCGTTTCCGCCGGTTGAAAGAGGCCGCCG
AACCGGGCCATTGAAGGGCC

Downstream 100 bases:

>100_bases
CGTCCCTCCCCGCGAGGGGGAGGGCAGGCGTCAGGCGTGGCCGACCTGTTCCTGTTCCTGGGCCTTGCGGGCCGCGTAGA
CGCCGGCGAAGTCGATCGGA

Product: DNA polymerase III epsilon chain

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MAREIVLDTETTGFDPLTGDRLVEIACLEIEDFIPTGRHFHAYIDPCRDMPAEAEKVHGLSTAFLRGKPKFEAPEIVEAF
LDFVADAPIVAHNAAFDRAFVNYELGLCSRAELPDHRWIDTLALAKQRFPGMHNSLDALCKRFKISLAEREKHGALIDTK
LLAAVYLELRGGRERRLELTSSAAVSAVHAATRNSYGARPRPLAPLSSDEERAVHAAFIREVVKSEELWGKFGL

Sequences:

>Translated_234_residues
MAREIVLDTETTGFDPLTGDRLVEIACLEIEDFIPTGRHFHAYIDPCRDMPAEAEKVHGLSTAFLRGKPKFEAPEIVEAF
LDFVADAPIVAHNAAFDRAFVNYELGLCSRAELPDHRWIDTLALAKQRFPGMHNSLDALCKRFKISLAEREKHGALIDTK
LLAAVYLELRGGRERRLELTSSAAVSAVHAATRNSYGARPRPLAPLSSDEERAVHAAFIREVVKSEELWGKFGL
>Mature_233_residues
AREIVLDTETTGFDPLTGDRLVEIACLEIEDFIPTGRHFHAYIDPCRDMPAEAEKVHGLSTAFLRGKPKFEAPEIVEAFL
DFVADAPIVAHNAAFDRAFVNYELGLCSRAELPDHRWIDTLALAKQRFPGMHNSLDALCKRFKISLAEREKHGALIDTKL
LAAVYLELRGGRERRLELTSSAAVSAVHAATRNSYGARPRPLAPLSSDEERAVHAAFIREVVKSEELWGKFGL

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=181, Percent_Identity=42.5414364640884, Blast_Score=147, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26065; Mature: 25934

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAREIVLDTETTGFDPLTGDRLVEIACLEIEDFIPTGRHFHAYIDPCRDMPAEAEKVHGL
CCCEEEEECCCCCCCCCCCCCEEEEEEEEHHHCCCCCCEEHHHHCHHHCCCCHHHHHCCH
STAFLRGKPKFEAPEIVEAFLDFVADAPIVAHNAAFDRAFVNYELGLCSRAELPDHRWID
HHHHHCCCCCCCCHHHHHHHHHHHHCCCEEECCCHHHHHHHEEECCCCCCCCCCCHHHHH
TLALAKQRFPGMHNSLDALCKRFKISLAEREKHGALIDTKLLAAVYLELRGGRERRLELT
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHEEHH
SSAAVSAVHAATRNSYGARPRPLAPLSSDEERAVHAAFIREVVKSEELWGKFGL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AREIVLDTETTGFDPLTGDRLVEIACLEIEDFIPTGRHFHAYIDPCRDMPAEAEKVHGL
CCEEEEECCCCCCCCCCCCCEEEEEEEEHHHCCCCCCEEHHHHCHHHCCCCHHHHHCCH
STAFLRGKPKFEAPEIVEAFLDFVADAPIVAHNAAFDRAFVNYELGLCSRAELPDHRWID
HHHHHCCCCCCCCHHHHHHHHHHHHCCCEEECCCHHHHHHHEEECCCCCCCCCCCHHHHH
TLALAKQRFPGMHNSLDALCKRFKISLAEREKHGALIDTKLLAAVYLELRGGRERRLELT
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHEEHH
SSAAVSAVHAATRNSYGARPRPLAPLSSDEERAVHAAFIREVVKSEELWGKFGL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA