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The map label for this gene is coaE [H]

Identifier: 197103470

GI number: 197103470

Start: 2320

End: 2931

Strand: Direct

Name: coaE [H]

Synonym: PHZ_c0004

Alternate gene names: 197103470

Gene position: 2320-2931 (Clockwise)

Preceding gene: 197103469

Following gene: 197103471

Centisome position: 0.06

GC content: 72.71

Gene sequence:

>612_bases
ATGAAGATCGTCGGCCTCACCGGCTCCATCGGCATGGGCAAGTCCACCACCGCGGCGATGTTCCGCGACGCCGGAATCCC
CGTCTACGACGCCGACGCGGCGGTCCACGACCTCTACGACCAGGGCGGCGCGGCCGTCGGGCCCGTGGGCGAGGCCTTCC
CGGGGGTTGTGAAGGACGGCCGCGTCGATCGCGAGGCGCTGCGCCAGCAGGTGCTGGGAAATCCCGAGGCGCTGAAGCGG
CTGAACGCCATCGTCCATCCCCTGGTCGGCCAGGACCGGGTGCAGTTCTTCAAGGCGGCCGAGGCGGCGGGCGCCGATAT
GGTGGTGCTGGACATCCCCCTGCTGTTCGAGACGGGCGGCCACGCGAACGTCGATGCGGTGGTGGTCGTCTCGGCGCCCC
CCCAGATGCAGCGCGAGCGGGTGCTGGCCCGGCCCGGCATGACCCCGGAACGGCTGGACGCCATCCTCGCCCAGCAGACC
CCGGACGCCGAGAAGCGGGCCCGGGCGCACTTCGTCGTCGACACCGGCCAGGGCCTGGAGCACGCCCGCGCCCAGGTGAT
GACCATCATCGCCGCCCTGCGGGCCGGGACGGACGGAGGGCGCGGCGACTAG

Upstream 100 bases:

>100_bases
GCCAGGCCGAACCCTCGTTCCAGGCCTTCTACGGCGCCAATCCGCCGGCGGGCGCGGACGTCCGCGCGCTGGCCCTGAAG
ACGCTGGAGGGCCGAGCCCC

Downstream 100 bases:

>100_bases
CCGCCTGCGCGTTTCCGCCGGTTGAAAGAGGCCGCCGAACCGGGCCATTGAAGGGCCATGGCGCGCGAAATCGTCCTCGA
CACCGAGACCACGGGCTTCG

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKIVGLTGSIGMGKSTTAAMFRDAGIPVYDADAAVHDLYDQGGAAVGPVGEAFPGVVKDGRVDREALRQQVLGNPEALKR
LNAIVHPLVGQDRVQFFKAAEAAGADMVVLDIPLLFETGGHANVDAVVVVSAPPQMQRERVLARPGMTPERLDAILAQQT
PDAEKRARAHFVVDTGQGLEHARAQVMTIIAALRAGTDGGRGD

Sequences:

>Translated_203_residues
MKIVGLTGSIGMGKSTTAAMFRDAGIPVYDADAAVHDLYDQGGAAVGPVGEAFPGVVKDGRVDREALRQQVLGNPEALKR
LNAIVHPLVGQDRVQFFKAAEAAGADMVVLDIPLLFETGGHANVDAVVVVSAPPQMQRERVLARPGMTPERLDAILAQQT
PDAEKRARAHFVVDTGQGLEHARAQVMTIIAALRAGTDGGRGD
>Mature_203_residues
MKIVGLTGSIGMGKSTTAAMFRDAGIPVYDADAAVHDLYDQGGAAVGPVGEAFPGVVKDGRVDREALRQQVLGNPEALKR
LNAIVHPLVGQDRVQFFKAAEAAGADMVVLDIPLLFETGGHANVDAVVVVSAPPQMQRERVLARPGMTPERLDAILAQQT
PDAEKRARAHFVVDTGQGLEHARAQVMTIIAALRAGTDGGRGD

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI110227607, Length=177, Percent_Identity=31.0734463276836, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI191252797, Length=192, Percent_Identity=28.6458333333333, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI191252795, Length=192, Percent_Identity=28.6458333333333, Blast_Score=75, Evalue=3e-14,
Organism=Homo sapiens, GI110227605, Length=177, Percent_Identity=31.0734463276836, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI110227603, Length=177, Percent_Identity=31.0734463276836, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI110227601, Length=177, Percent_Identity=31.0734463276836, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI205277394, Length=177, Percent_Identity=31.0734463276836, Blast_Score=74, Evalue=7e-14,
Organism=Escherichia coli, GI1786292, Length=176, Percent_Identity=35.2272727272727, Blast_Score=97, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17554944, Length=197, Percent_Identity=29.4416243654822, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6320402, Length=204, Percent_Identity=30.3921568627451, Blast_Score=91, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24644728, Length=199, Percent_Identity=30.6532663316583, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24658602, Length=187, Percent_Identity=29.9465240641711, Blast_Score=81, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21337; Mature: 21337

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVGLTGSIGMGKSTTAAMFRDAGIPVYDADAAVHDLYDQGGAAVGPVGEAFPGVVKDG
CEEEEECCCCCCCCCHHHHHHHHCCCCEEECCHHHHHHHHCCCCCCCCCCHHCCCCCCCC
RVDREALRQQVLGNPEALKRLNAIVHPLVGQDRVQFFKAAEAAGADMVVLDIPLLFETGG
CCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECEEEECCC
HANVDAVVVVSAPPQMQRERVLARPGMTPERLDAILAQQTPDAEKRARAHFVVDTGQGLE
CCCCCEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHEEEEEECCCCHH
HARAQVMTIIAALRAGTDGGRGD
HHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKIVGLTGSIGMGKSTTAAMFRDAGIPVYDADAAVHDLYDQGGAAVGPVGEAFPGVVKDG
CEEEEECCCCCCCCCHHHHHHHHCCCCEEECCHHHHHHHHCCCCCCCCCCHHCCCCCCCC
RVDREALRQQVLGNPEALKRLNAIVHPLVGQDRVQFFKAAEAAGADMVVLDIPLLFETGG
CCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEECEEEECCC
HANVDAVVVVSAPPQMQRERVLARPGMTPERLDAILAQQTPDAEKRARAHFVVDTGQGLE
CCCCCEEEEEECCCHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHEEEEEECCCCHH
HARAQVMTIIAALRAGTDGGRGD
HHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]