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The map label for this gene is luxS [H]

Identifier: 195978667

GI number: 195978667

Start: 1613077

End: 1613607

Strand: Direct

Name: luxS [H]

Synonym: Sez_1565

Alternate gene names: 195978667

Gene position: 1613077-1613607 (Clockwise)

Preceding gene: 195978652

Following gene: 195978672

Centisome position: 79.69

GC content: 44.44

Gene sequence:

>531_bases
GTGATTTTATGTTATGATATTGATAAAAATAAAAAGGAGTTTCTAATGCCAAAAGAAGTTATTGTTGAAAGCTTTGAGCT
TGATCATACCATTGTCAAGGCACCCTATGTAAGACTAATCTCTGAGGAATTTGGACCCAAGGGAGATGTGATTACAAATT
TTGATGTTCGGCTTGTTCAGCCTAATCAGGCTGCCATTGAGACGGCCGGTTTACACACCATCGAGCATTTATTAGCCAAG
CTCATTCGTCAACGCATTGATGGAATGATTGATTGCTCCCCCTTTGGCTGCCGCACAGGCTTTCACCTCATCATGTGGGG
CAAGCACAGTTCAACAGACATTGCTAAGGTTATCACGTCCAGCCTAGAGGAAATCGCTACAGGCATCACTTGGGAGGACG
TTCCCGGAACAACCATTGAATCCTGCGGCAATTACAAGGACCACAGCCTTTTTGCTGCTAAGGAATGGGCCCAGCTTATT
CTCAAGCAAGGGATCTCTGATGATCCATTTAACCGCCATGTCACCTCATAA

Upstream 100 bases:

>100_bases
AATAATAGTTTAGTTTTCATTAATAGAAAGCCATCTCCTAGTCTATCATAAAATGAAGATTTAGACAATTTAAAATCCAC
CTGCATTTTTCTAAAATCTA

Downstream 100 bases:

>100_bases
CAATGAAAGCCTCGCTTTTCTGCTAATGAAAAGGAGGCTTTTAATGCATTCAAAAAGGTGCCAAAGGCAGGGCTCAATCC
CTTTGCCTTTTAGCACCTGT

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MILCYDIDKNKKEFLMPKEVIVESFELDHTIVKAPYVRLISEEFGPKGDVITNFDVRLVQPNQAAIETAGLHTIEHLLAK
LIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVITSSLEEIATGITWEDVPGTTIESCGNYKDHSLFAAKEWAQLI
LKQGISDDPFNRHVTS

Sequences:

>Translated_176_residues
MILCYDIDKNKKEFLMPKEVIVESFELDHTIVKAPYVRLISEEFGPKGDVITNFDVRLVQPNQAAIETAGLHTIEHLLAK
LIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVITSSLEEIATGITWEDVPGTTIESCGNYKDHSLFAAKEWAQLI
LKQGISDDPFNRHVTS
>Mature_176_residues
MILCYDIDKNKKEFLMPKEVIVESFELDHTIVKAPYVRLISEEFGPKGDVITNFDVRLVQPNQAAIETAGLHTIEHLLAK
LIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVITSSLEEIATGITWEDVPGTTIESCGNYKDHSLFAAKEWAQLI
LKQGISDDPFNRHVTS

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=149, Percent_Identity=34.8993288590604, Blast_Score=108, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 19802; Mature: 19802

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILCYDIDKNKKEFLMPKEVIVESFELDHTIVKAPYVRLISEEFGPKGDVITNFDVRLVQ
CEEEEECCCCCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEC
PNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVITS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCEEEEECCCCCHHHHHHHHH
SLEEIATGITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVTS
HHHHHHCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MILCYDIDKNKKEFLMPKEVIVESFELDHTIVKAPYVRLISEEFGPKGDVITNFDVRLVQ
CEEEEECCCCCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEECCEEEEEC
PNQAAIETAGLHTIEHLLAKLIRQRIDGMIDCSPFGCRTGFHLIMWGKHSSTDIAKVITS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCEECCCCCCCCCCCEEEEECCCCCHHHHHHHHH
SLEEIATGITWEDVPGTTIESCGNYKDHSLFAAKEWAQLILKQGISDDPFNRHVTS
HHHHHHCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA