Click here to switch to the map view.

The map label for this gene is cynR [C]

Identifier: 195978541

GI number: 195978541

Start: 1480229

End: 1481131

Strand: Direct

Name: cynR [C]

Synonym: Sez_1438

Alternate gene names: 195978541

Gene position: 1480229-1481131 (Clockwise)

Preceding gene: 195978534

Following gene: 195978560

Centisome position: 73.13

GC content: 35.11

Gene sequence:

>903_bases
ATGGATATTAAACATTTACGCTTTTTCATTGCTATTGTAGAAAATAATTTTAACCTGAGCCGTACCGCTCAACAGCTTTA
CATTTCCCAGCCCACCCTCAGTATTATGATTAATGATTTTGAAGAAAAGCAGGGCATTAAACTCTTTAATAAAAAATACA
ATAAAATCCTCGGTTTGACCATGACAGGCAAGCAATTTTATGAGGATTCTTTGGAGGTCATCCGCAAATATGACAAGATG
CACCAAAATCTCTTTTCCACCAATCAAAAGTTGGACGGTAATATCACTATCGGCATTCCTCCATTAATTCTGTCAATTGT
TTTTTCAAAAATCATGCCAGAAATTATTCTAGAAAATCCCAATATCCACTTTAATATTAAGGAGTATGGTGCTAATCGGC
TACGTCAGGAATTGATTTTAGAGAATGTGGATATCGCCATTCTCCTGCATCCTGAACGAATTGCTGCAAACACCATTGAT
TCTTTCCAAATCCAAGAATCTGAGCTCTGTGTATTTGTTTCCAAGGACCACCATTTGGCCAATAAAAAAATCCTGACTTG
GATAGAACTCCACAATGAAAAACTAGCTATATTTGATAAAACTTTCATGATTCACCATCTCATTAAGGAAAAATGTAAGT
ATACTGACATTAACCCCCAAATCATTCTGGAATCTGCTTCTTGGGACTTTCTGATCAATTCTACTCGTATCAACCCTCAA
CTAATGACGATTATTCCAAAACCAACGGTAGATAGCTATGGTTTTCAGGATATTGTGGCTATTCCTATGGAAAATCCTAT
TCCTTGGAAAGTCATGGTCAGTCGTCTCAAAAAAGATCATTATTCCACTATAGAAGAATATATTTTCAACAAAATGCTTG
AAAAATTTCATGTAATCGAATAA

Upstream 100 bases:

>100_bases
TTTATATGACTATAAAAATTTTTTATTATTTTTTATTGACAGCTATAAAAATTATTATTAGTATGAAGAAAAAGACATCT
GAAATGAAAGAAGAGGCAAT

Downstream 100 bases:

>100_bases
AGACTAACAAGTGATCCCTTCCACACGACTGCACGTGCCCTTCGACATATGGCACTTCAACTAACCCTTAGCGCATATGG
AAACAGCTCAATTCTTTTTG

Product: transcriptional regulator LysR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQGIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKM
HQNLFSTNQKLDGNITIGIPPLILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
SFQIQESELCVFVSKDHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDINPQIILESASWDFLINSTRINPQ
LMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRLKKDHYSTIEEYIFNKMLEKFHVIE

Sequences:

>Translated_300_residues
MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQGIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKM
HQNLFSTNQKLDGNITIGIPPLILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
SFQIQESELCVFVSKDHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDINPQIILESASWDFLINSTRINPQ
LMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRLKKDHYSTIEEYIFNKMLEKFHVIE
>Mature_300_residues
MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQGIKLFNKKYNKILGLTMTGKQFYEDSLEVIRKYDKM
HQNLFSTNQKLDGNITIGIPPLILSIVFSKIMPEIILENPNIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTID
SFQIQESELCVFVSKDHHLANKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDINPQIILESASWDFLINSTRINPQ
LMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRLKKDHYSTIEEYIFNKMLEKFHVIE

Specific function: Positive Regulatory Protein For The Cyn Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=297, Percent_Identity=21.8855218855219, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788887, Length=202, Percent_Identity=25.7425742574257, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787879, Length=205, Percent_Identity=28.2926829268293, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI2367136, Length=226, Percent_Identity=23.8938053097345, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787530, Length=261, Percent_Identity=20.6896551724138, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790399, Length=299, Percent_Identity=22.0735785953177, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=194, Percent_Identity=24.2268041237113, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35204; Mature: 35204

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQGIKLFNKKYNKILGLT
CCHHHEEEEEEEEECCCCHHHHHHHHEECCCEEEEEEECHHHCCCHHHHHHHHHHEEEEE
MTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPLILSIVFSKIMPEIILENP
ECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHEECCC
NIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTIDSFQIQESELCVFVSKDHHLA
CEEEEEHHHCHHHHHHHHHHCCCCEEEEECCHHHHHCCCCCCEEECCCEEEEEECCCCCC
NKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDINPQIILESASWDFLINSTRINPQ
CCCEEEEEEECCCEEEEHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCE
LMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRLKKDHYSTIEEYIFNKMLEKFHVIE
EEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDIKHLRFFIAIVENNFNLSRTAQQLYISQPTLSIMINDFEEKQGIKLFNKKYNKILGLT
CCHHHEEEEEEEEECCCCHHHHHHHHEECCCEEEEEEECHHHCCCHHHHHHHHHHEEEEE
MTGKQFYEDSLEVIRKYDKMHQNLFSTNQKLDGNITIGIPPLILSIVFSKIMPEIILENP
ECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHEECCC
NIHFNIKEYGANRLRQELILENVDIAILLHPERIAANTIDSFQIQESELCVFVSKDHHLA
CEEEEEHHHCHHHHHHHHHHCCCCEEEEECCHHHHHCCCCCCEEECCCEEEEEECCCCCC
NKKILTWIELHNEKLAIFDKTFMIHHLIKEKCKYTDINPQIILESASWDFLINSTRINPQ
CCCEEEEEEECCCEEEEHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCCCCE
LMTIIPKPTVDSYGFQDIVAIPMENPIPWKVMVSRLKKDHYSTIEEYIFNKMLEKFHVIE
EEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]