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The map label for this gene is xylR [H]

Identifier: 195978534

GI number: 195978534

Start: 1473149

End: 1474351

Strand: Direct

Name: xylR [H]

Synonym: Sez_1431

Alternate gene names: 195978534

Gene position: 1473149-1474351 (Clockwise)

Preceding gene: 195978524

Following gene: 195978541

Centisome position: 72.78

GC content: 43.47

Gene sequence:

>1203_bases
ATGAAGACGGATAAACAACAAGAGCTTTACGCAAAAATTTTAGATACGATTTATGCCCAACGGCCTATTTCACGCATTGA
TATTTCAAAGCTAACGCACATCACACCTGCTACAGTAGGGGCTATCACTAAAGAGCTGCTAGCACAGGGGTGGATACACG
AAATCGGAGAGCTGACGGACCACTCCGTTGGCCGCAAAAAAATATTACTTGATGCTTCGGCTAACGCCTTTTATTTTGCT
GGTGTCGAATTGTCCGAAAAGCATTTCTATTTGGTCATTACAGATAACCTGGGCACCATCTATGCCAAGCACAACCAACA
GATCGACCCAAGTATTTCCTCCTACTACAAATCGGACTATATCTCTGAGCTGATCCAAGCCTTCCTCAAGCAGCACAAGC
ACTATGATGTACAAGCCATAGGAATAGCACTGCCTGGGCATTACGATCATTCCACCTCCAGCTCAACGCATATTAACACC
AACAATCCCATCTGGCAGCAGGTCGATTTAACCGCAATTGCGAAGTCCTTCCCTATTCCAGTGGTCTTTAGCAACAATGC
TCACTGTATGATTATTGCTAAGCGTTTATACGAGCAACAAGCACATAATCACAATTTTATTTTCTTCCATGTAGGACGAG
GCATGCACTGCTCTTATATGTATAAGGGGGTCATTTATAGCCGTCACAATGCTGTTGTTGGGGAAATCGGACATACCATT
GTCAACCCCACTGGAGAGCTTTGTGAATGTGGTAAAAAAGGCTGTTTACAGACCTATGCCAGCAATGCCTGGCTACTCAA
AAAAGCAAAGCTGCTGCATCAGTATGCCCCCAATTCTCATCTAAGAAGCCTTGTCGATAAGGCCTGTGAGCTCAAGCTAG
ACCATCTCTTGATTGCCTATGAGCTTGGTGATGTCGGGGTGACCACGCTCATTCACACAGCTATTGATTACCTTGTTTTA
TCCCTGTCTAACCTCTCCTTGCTGATTGATACCGAGCAAATCTATCTCCATGGCAGATTTATCAGCCATCCTCTTATATC
CTCCAAAATTCTGCAGGCCCTGCAAAATGACATTAAGCTTCTTAGCAATCAAAAAAAGCCAGAAATCATTGTCATGCCTT
TTTCTGTCTATAATGCCGCTGTGGGAGCTACAGGCTTATGTATAGATGAGCTTTACCTCAATTATAAAAACAAATATGAT
TGA

Upstream 100 bases:

>100_bases
ACAAATAAAGTATATTCTATTTACCAATATTTGTCAACGTTTTCAGGAAGGATTTTTAATTCTTTTTTGGTATGATAGAG
GTACGATAATAGAGGTTACT

Downstream 100 bases:

>100_bases
TAACCCCCACACCAATATCAGCTAAAGCTTTAAAGCCCATTTGAGAAGCCCTTTCTCAAGTGGGCTTTTGCATTATGCGA
CTTTCAGTCCATCTCGCTCC

Product: xylose repressor XylR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITKELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFA
GVELSEKHFYLVITDNLGTIYAKHNQQIDPSISSYYKSDYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYEQQAHNHNFIFFHVGRGMHCSYMYKGVIYSRHNAVVGEIGHTI
VNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYAPNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVL
SLSNLSLLIDTEQIYLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELYLNYKNKYD

Sequences:

>Translated_400_residues
MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITKELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFA
GVELSEKHFYLVITDNLGTIYAKHNQQIDPSISSYYKSDYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYEQQAHNHNFIFFHVGRGMHCSYMYKGVIYSRHNAVVGEIGHTI
VNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYAPNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVL
SLSNLSLLIDTEQIYLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELYLNYKNKYD
>Mature_400_residues
MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITKELLAQGWIHEIGELTDHSVGRKKILLDASANAFYFA
GVELSEKHFYLVITDNLGTIYAKHNQQIDPSISSYYKSDYISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINT
NNPIWQQVDLTAIAKSFPIPVVFSNNAHCMIIAKRLYEQQAHNHNFIFFHVGRGMHCSYMYKGVIYSRHNAVVGEIGHTI
VNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYAPNSHLRSLVDKACELKLDHLLIAYELGDVGVTTLIHTAIDYLVL
SLSNLSLLIDTEQIYLHGRFISHPLISSKILQALQNDIKLLSNQKKPEIIVMPFSVYNAAVGATGLCIDELYLNYKNKYD

Specific function: Transcriptional repressor of xylose-utilizing enzymes [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566325, Length=264, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI298566315, Length=264, Percent_Identity=24.2424242424242, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI4885285, Length=264, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI190014632, Length=264, Percent_Identity=24.2424242424242, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1786891, Length=260, Percent_Identity=27.6923076923077, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787878, Length=289, Percent_Identity=23.8754325259516, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI87082127, Length=338, Percent_Identity=24.2603550295858, Blast_Score=86, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 45034; Mature: 45034

Theoretical pI: Translated: 7.93; Mature: 7.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITKELLAQGWIHEIGELTD
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
HSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYAKHNQQIDPSISSYYKSDY
CCCCCEEEEEECCCCEEEEEEEEECCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHH
ISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINTNNPIWQQVDLTAIAKSFPIP
HHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCE
VVFSNNAHCMIIAKRLYEQQAHNHNFIFFHVGRGMHCSYMYKGVIYSRHNAVVGEIGHTI
EEECCCCEEEEEHHHHHHHHCCCCCEEEEECCCCCEEHHHHHCEEEECCCCHHHHHCHHH
VNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYAPNSHLRSLVDKACELKLDHLLIAY
CCCCHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHEEHHHEEEEE
ELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQIYLHGRFISHPLISSKILQALQNDIKL
EECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHH
LSNQKKPEIIVMPFSVYNAAVGATGLCIDELYLNYKNKYD
HCCCCCCEEEEEEHHHHHHHHCCCHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKTDKQQELYAKILDTIYAQRPISRIDISKLTHITPATVGAITKELLAQGWIHEIGELTD
CCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHC
HSVGRKKILLDASANAFYFAGVELSEKHFYLVITDNLGTIYAKHNQQIDPSISSYYKSDY
CCCCCEEEEEECCCCEEEEEEEEECCCEEEEEEECCCCEEEECCCCCCCCHHHHHHHHHH
ISELIQAFLKQHKHYDVQAIGIALPGHYDHSTSSSTHINTNNPIWQQVDLTAIAKSFPIP
HHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHCCCE
VVFSNNAHCMIIAKRLYEQQAHNHNFIFFHVGRGMHCSYMYKGVIYSRHNAVVGEIGHTI
EEECCCCEEEEEHHHHHHHHCCCCCEEEEECCCCCEEHHHHHCEEEECCCCHHHHHCHHH
VNPTGELCECGKKGCLQTYASNAWLLKKAKLLHQYAPNSHLRSLVDKACELKLDHLLIAY
CCCCHHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHEEHHHEEEEE
ELGDVGVTTLIHTAIDYLVLSLSNLSLLIDTEQIYLHGRFISHPLISSKILQALQNDIKL
EECCCHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHH
LSNQKKPEIIVMPFSVYNAAVGATGLCIDELYLNYKNKYD
HCCCCCCEEEEEEHHHHHHHHCCCHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2544559 [H]