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The map label for this gene is agrA [H]

Identifier: 195978091

GI number: 195978091

Start: 1004615

End: 1005352

Strand: Direct

Name: agrA [H]

Synonym: Sez_0964

Alternate gene names: 195978091

Gene position: 1004615-1005352 (Clockwise)

Preceding gene: 195978090

Following gene: 195978092

Centisome position: 49.63

GC content: 38.48

Gene sequence:

>738_bases
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACTTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACCACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAAGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Upstream 100 bases:

>100_bases
ATGCTAAGTTCATGAAGGAGAGCGTTCTAGCTATCACTTGTTCAAAAAGCTGCTTTAGTCTCCTAAAAAACGATAAGCTA
AAGCAACAAGGAGGTTCTAA

Downstream 100 bases:

>100_bases
CAGTAAAAGAATGCCATGTGGAAGCCATCATTTGCTTTTTAATCAACCTCGTTGATACCATTTACCTTAAGGGCTATTCA
TTATAAGGATATTTAGTCAA

Product: accessory gene regulator protein A, response regulator FasA or ComE or BlpR

Products: NADP; 2 glutathione [C]

Alternate protein names: NA

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Sequences:

>Translated_245_residues
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH
>Mature_245_residues
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Specific function: Required for high-level post-exponential phase expression of a series of secreted proteins [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 28895; Mature: 28895

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDS
CEEEEEECCCCCCEEHEEHHHHHHHHHCCCCCHHEECCCHHHHHHHHHHCCCEEEEEEEH
QIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSD
HHCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEEEEEHHHHHHHHHHHHHHHHH
RIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLFIETSSTPHKLILHSQNERIE
HHHHEEEEEEECCCCCCCCCEEEEEEECEEEEECCEEEEEEEECCCCCEEEEECCCCCCH
FYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
HHHHHHHHHHCCHHHHHHHHHEECCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHH
IKALH
HHHCC
>Mature Secondary Structure
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDS
CEEEEEECCCCCCEEHEEHHHHHHHHHCCCCCHHEECCCHHHHHHHHHHCCCEEEEEEEH
QIRNDEKKGLAVAREIRKRDPYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSD
HHCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEEEEEEHHHHHHHHHHHHHHHHH
RIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLFIETSSTPHKLILHSQNERIE
HHHHEEEEEEECCCCCCCCCEEEEEEECEEEEECCEEEEEEEECCCCCEEEEECCCCCCH
FYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
HHHHHHHHHHCCHHHHHHHHHEECCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHH
IKALH
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NADPH2; oxidized glutathione [C]

Specific reaction: NADPH2 + oxidized glutathione = NADP + 2 glutathione [C]

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a disulfide as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA