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The map label for this gene is spxA [H]

Identifier: 195978034

GI number: 195978034

Start: 950724

End: 951128

Strand: Direct

Name: spxA [H]

Synonym: Sez_0907

Alternate gene names: 195978034

Gene position: 950724-951128 (Clockwise)

Preceding gene: 195978033

Following gene: 195978035

Centisome position: 46.97

GC content: 40.25

Gene sequence:

>405_bases
ATGATTACCTTATTTCTATCACCAAGCTGTACTAGCTGCCGTAAGGCCAGAGCCTGGCTCACCAAGCATGACGTTGACTT
TCAAGAGCATAATATTATTACCAGCCCGCTTAGTCGTGAGGAGCTGTTAGCGATCCTATCCTTTACTGAAAATGGAACAG
AGGATATTATTTCAACACGATCAAAGGTTTTTCAAAAATTGGATATTGATATTGATGAGCTGTCTATCATGGATTTGATT
AATTTGATCGCAAAGAACCCTAGCCTTCTTCGTAGGCCAATCATTATGGATAGTAAGCGCATGCAAATTGGCTTTAATGA
AGATGAGATTAGGGCATTTTTGCCAAGGGATTATCGTAAGCAAGAACTGCGTCAAGCAACCATAAAGGCAGAAATCGAGG
GATAA

Upstream 100 bases:

>100_bases
ACTCAAGCAGGATAAAGAAGCTGCCATAAATTGGAAAAAAGATAGCCAAGGCTATTAAATTTTTGTATAATAAGGTAAGC
ACAATTAACAGAGGAAAAGT

Downstream 100 bases:

>100_bases
CATGTCAGATCATTATCATTACCCACTTGATGCAAGCTGGAGCACTGAAGAGATAACATCAGTGCTTCATTTTTTAAATC
AGGTAGAGTTAGCCTATGAG

Product: transcriptional regulator Spx

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLAILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLI
NLIAKNPSLLRRPIIMDSKRMQIGFNEDEIRAFLPRDYRKQELRQATIKAEIEG

Sequences:

>Translated_134_residues
MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLAILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLI
NLIAKNPSLLRRPIIMDSKRMQIGFNEDEIRAFLPRDYRKQELRQATIKAEIEG
>Mature_134_residues
MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLAILSFTENGTEDIISTRSKVFQKLDIDIDELSIMDLI
NLIAKNPSLLRRPIIMDSKRMQIGFNEDEIRAFLPRDYRKQELRQATIKAEIEG

Specific function: Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes invo

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family. Spx subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335
- InterPro:   IPR006504 [H]

Pfam domain/function: PF03960 ArsC [H]

EC number: NA

Molecular weight: Translated: 15522; Mature: 15522

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLAILSFTENGTEDIISTR
CEEEEECCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHCCCCHHHHHHHH
SKVFQKLDIDIDELSIMDLINLIAKNPSLLRRPIIMDSKRMQIGFNEDEIRAFLPRDYRK
HHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCEEECCCHHHHHHHCCCHHHH
QELRQATIKAEIEG
HHHHHHHHHEECCC
>Mature Secondary Structure
MITLFLSPSCTSCRKARAWLTKHDVDFQEHNIITSPLSREELLAILSFTENGTEDIISTR
CEEEEECCCCHHHHHHHHHHHHCCCCCCCCCEECCCCCHHHHHHHHHHCCCCHHHHHHHH
SKVFQKLDIDIDELSIMDLINLIAKNPSLLRRPIIMDSKRMQIGFNEDEIRAFLPRDYRK
HHHHHHHCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCEEECCCHHHHHHHCCCHHHH
QELRQATIKAEIEG
HHHHHHHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]