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The map label for this gene is glmS [H]

Identifier: 195978011

GI number: 195978011

Start: 927910

End: 929721

Strand: Direct

Name: glmS [H]

Synonym: Sez_0884

Alternate gene names: 195978011

Gene position: 927910-929721 (Clockwise)

Preceding gene: 195978010

Following gene: 195978012

Centisome position: 45.84

GC content: 44.26

Gene sequence:

>1812_bases
ATGTGTGGAATTGTTGGAGTTGTCGGTAGTCGTAATGCGACTGACATCTTGATGCAGGGACTGGAAAAATTAGAGTATCG
TGGTTATGATTCAGCTGGTATTTTTGTGTCAGATGGCAGGACGTCCAATTTGGTAAAATCTGTTGGACGCATTGCAGATT
TACGCTCTAAGATTGGTATTGATGTTGTCGGAACAACTGGTATTGGTCATACACGTTGGGCAACGCATGGTCAAGCAACA
GAGGAAAATGCTCACCCTCATACCTCTCAGACAGGTCGCTTTGTTCTTGTTCATAATGGTGTGATTGAAAATTACCTCCA
GATGAAGGAGCAGTACCTTGCTGGACACACGTTTAAAGGACAAACAGACACCGAAATTGCAGTTCATTTGATTGGAGCAT
TTGTTGAAGAAGGCTGTTCAGTCTTAGAGGCTTTTAAAAAGGCTTTATCAATCATTGAAGGCTCCTATGCCTTTGCCTTA
ATTGATACAGAGGATATGGATACGATCTATGTCGCTAAGAATAAATCCCCATTGTTGATTGGCCTTGGTGAGGGCTATAA
CATGGTTTGTTCAGACGCTATGGCCATGATTCGTGAAACCAGCGAATTTATGGAAATCCATGACAAGGAGCTGGTTATCC
TGACAAAGGATTCAGCAAGGGTGACCGATTATGCCGGAAATCCTATTGAACGTCAGTCATATACTGCAGAGCTTGATCTT
TCAGATATTGGCAAGGGGACCTATCCATTTTACATGCTAAAGGAAATTGACGAGCAGCCAACAGTGATGCGTCGCTTGAT
TTCAACCTATGCAGACGCCAAGGGACAGATGATGATTGATCCAGCTATCATAAGGTCTGTCCAAGAGGCTGATCGTATCT
ATATTCTTGCAGCTGGGACCTCTTATCATGCTGGTTTTGCTTCTAAGTCAATGCTGGAGCGTTTGACTGATACGCCTGTT
GAATTAGGGGTTGCTTCTGAGTGGGGCTACAATATGCCGCTATTGAGCAAAAAGCCAATGTTTATCCTCTTGAGCCAGTC
CGGTGAGACAGCAGATAGCCGTCAGGTTTTGGTCAAGGCAAATGAGCTGGGAATTCCAAGCCTAACAGTGACAAATGTTC
CTGGCTCAACCCTATCACGTGAAGCGACCTACACTATGCTGCTTCATGCAGGTCCAGAAATTGCAGTTGCATCAACTAAA
GCCTACACAGCTCAGGTCGCTGCACTTGCCTTTCTAGCTAAGGCAGTTGGTGAGGCTAATGGCAAGAAGGAAGCTATTAG
CTTTGATTTGGTTCATGAATTGTCATTGGTCGCTCAGTCTATTGAGGCCACCTTATCTGATAAGGAGCTGATTGCTGAGA
AGGTGCAGACCTTATTGGCAACAACACGCAATGCGTTTTACATTGGTCGTGGCAATGATTATTATGTTGCTATGGAGGCT
GCACTAAAATTAAAAGAAATTTCATACATTCAGTGTGAAGGGTTTGCAGCTGGTGAGCTAAAGCATGGGACTATTTCACT
GATTGAGGATGGCACACCTGTTATTGGACTTATTTCTTCAAGTGAGCTGGTTGCTGCACATACACGTGGCAATATCCAAG
AGGTGGCTGCACGTGGCGCTCATGTGTTGACAGTTGTTGAGGAGGGCTTAGAGCGTGAGGGAGATGACATTATTATTAAT
AAGGTGCACCCATTCTTAGCGCCGATTGCTATGGTTATTCCGACTCAATTAATTGCTTACTATGCGTCCTTGCAGCGTGG
TTTAGATGTAGATAAGCCTCGTAATTTAGCCAAGGCTGTTACAGTTGAGTAA

Upstream 100 bases:

>100_bases
TATACTCTAAATATAACGTTTTAGTCGGTTTATATCTGACTATACCAATTATATTGATCATTAAAGAAAGTAGTAAGCTA
GCTTACTGAGGTGTTAAGTT

Downstream 100 bases:

>100_bases
TAGTTGCCTGCTTAAAATGAGGCAGCAGGGTCCTGAAGCCTATTTGAAACGAGCTTGACATGATGTTATGTCAGGCTCGT
TTTTTAGTGCTTGCCTGGTC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNLVKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQAT
EENAHPHTSQTGRFVLVHNGVIENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDSARVTDYAGNPIERQSYTAELDL
SDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQMMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLERLTDTPV
ELGVASEWGYNMPLLSKKPMFILLSQSGETADSRQVLVKANELGIPSLTVTNVPGSTLSREATYTMLLHAGPEIAVASTK
AYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKELIAEKVQTLLATTRNAFYIGRGNDYYVAMEA
ALKLKEISYIQCEGFAAGELKHGTISLIEDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIIN
KVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE

Sequences:

>Translated_603_residues
MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNLVKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQAT
EENAHPHTSQTGRFVLVHNGVIENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDSARVTDYAGNPIERQSYTAELDL
SDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQMMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLERLTDTPV
ELGVASEWGYNMPLLSKKPMFILLSQSGETADSRQVLVKANELGIPSLTVTNVPGSTLSREATYTMLLHAGPEIAVASTK
AYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKELIAEKVQTLLATTRNAFYIGRGNDYYVAMEA
ALKLKEISYIQCEGFAAGELKHGTISLIEDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIIN
KVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
>Mature_603_residues
MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNLVKSVGRIADLRSKIGIDVVGTTGIGHTRWATHGQAT
EENAHPHTSQTGRFVLVHNGVIENYLQMKEQYLAGHTFKGQTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFAL
IDTEDMDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDSARVTDYAGNPIERQSYTAELDL
SDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQMMIDPAIIRSVQEADRIYILAAGTSYHAGFASKSMLERLTDTPV
ELGVASEWGYNMPLLSKKPMFILLSQSGETADSRQVLVKANELGIPSLTVTNVPGSTLSREATYTMLLHAGPEIAVASTK
AYTAQVAALAFLAKAVGEANGKKEAISFDLVHELSLVAQSIEATLSDKELIAEKVQTLLATTRNAFYIGRGNDYYVAMEA
ALKLKEISYIQCEGFAAGELKHGTISLIEDGTPVIGLISSSELVAAHTRGNIQEVAARGAHVLTVVEEGLEREGDDIIIN
KVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=698, Percent_Identity=31.8051575931232, Blast_Score=291, Evalue=1e-78,
Organism=Homo sapiens, GI4826742, Length=696, Percent_Identity=30.8908045977011, Blast_Score=287, Evalue=2e-77,
Organism=Escherichia coli, GI1790167, Length=615, Percent_Identity=39.8373983739837, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1788651, Length=249, Percent_Identity=24.8995983935743, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17539970, Length=434, Percent_Identity=31.5668202764977, Blast_Score=203, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17532899, Length=427, Percent_Identity=30.9133489461358, Blast_Score=200, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17532897, Length=427, Percent_Identity=30.9133489461358, Blast_Score=199, Evalue=3e-51,
Organism=Saccharomyces cerevisiae, GI6322745, Length=436, Percent_Identity=33.4862385321101, Blast_Score=215, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6323731, Length=386, Percent_Identity=27.720207253886, Blast_Score=148, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6323730, Length=207, Percent_Identity=35.2657004830918, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI21357745, Length=695, Percent_Identity=30.6474820143885, Blast_Score=304, Evalue=1e-82,
Organism=Drosophila melanogaster, GI28573187, Length=261, Percent_Identity=24.904214559387, Blast_Score=66, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65413; Mature: 65413

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNLVKSVGRIADLRSKIGI
CCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCE
DVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVIENYLQMKEQYLAGHTFKG
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCC
QTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFALIDTEDMDTIYVAKNKSPLLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCEEE
GLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDSARVTDYAGNPIERQSYTAELDL
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCCCCEEEEECH
SDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQMMIDPAIIRSVQEADRIYILAAGT
HHCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHCCCEEEEEEECC
SYHAGFASKSMLERLTDTPVELGVASEWGYNMPLLSKKPMFILLSQSGETADSRQVLVKA
CCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEE
NELGIPSLTVTNVPGSTLSREATYTMLLHAGPEIAVASTKAYTAQVAALAFLAKAVGEAN
CCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHCCC
GKKEAISFDLVHELSLVAQSIEATLSDKELIAEKVQTLLATTRNAFYIGRGNDYYVAMEA
CCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEH
ALKLKEISYIQCEGFAAGELKHGTISLIEDGTPVIGLISSSELVAAHTRGNIQEVAARGA
HHHHHHCCEEEECCEECCCCCCCEEEEEECCCCEEEEECCCCEEEEECCCCHHHHHHCCC
HVLTVVEEGLEREGDDIIINKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAV
EEEHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEE
TVE
ECC
>Mature Secondary Structure
MCGIVGVVGSRNATDILMQGLEKLEYRGYDSAGIFVSDGRTSNLVKSVGRIADLRSKIGI
CCCEEEECCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHCCE
DVVGTTGIGHTRWATHGQATEENAHPHTSQTGRFVLVHNGVIENYLQMKEQYLAGHTFKG
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCCC
QTDTEIAVHLIGAFVEEGCSVLEAFKKALSIIEGSYAFALIDTEDMDTIYVAKNKSPLLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEECCCCCEEE
GLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDSARVTDYAGNPIERQSYTAELDL
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEECCCCCCCCCCCEEEEECH
SDIGKGTYPFYMLKEIDEQPTVMRRLISTYADAKGQMMIDPAIIRSVQEADRIYILAAGT
HHCCCCCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHCCCEEEEEEECC
SYHAGFASKSMLERLTDTPVELGVASEWGYNMPLLSKKPMFILLSQSGETADSRQVLVKA
CCCCCHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCEEEEEE
NELGIPSLTVTNVPGSTLSREATYTMLLHAGPEIAVASTKAYTAQVAALAFLAKAVGEAN
CCCCCCEEEEECCCCCCCCCCCEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHCCC
GKKEAISFDLVHELSLVAQSIEATLSDKELIAEKVQTLLATTRNAFYIGRGNDYYVAMEA
CCCCEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEEEH
ALKLKEISYIQCEGFAAGELKHGTISLIEDGTPVIGLISSSELVAAHTRGNIQEVAARGA
HHHHHHCCEEEECCEECCCCCCCEEEEEECCCCEEEEECCCCEEEEECCCCHHHHHHCCC
HVLTVVEEGLEREGDDIIINKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAV
EEEHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHEE
TVE
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA