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The map label for this gene is lepB [H]

Identifier: 195978010

GI number: 195978010

Start: 927176

End: 927733

Strand: Direct

Name: lepB [H]

Synonym: Sez_0883

Alternate gene names: 195978010

Gene position: 927176-927733 (Clockwise)

Preceding gene: 195978009

Following gene: 195978011

Centisome position: 45.81

GC content: 36.2

Gene sequence:

>558_bases
ATGGTAAAGCGAGATTTTATAAGAAATATATTGTTGTTATTGATTCTTATTGTGGGAGCTGTCCTTCTTAGAATATTTGT
TTTTTCGACCTATCGAGTCACGTCAGAGGCCTCAAATGCCTATTTGAATAAGGGCGATTTAATCACCATTAAGAAAAATA
TTGAGCCTAAATATAAGGATTTTGTGGTTTATACGGTTGATAAAAAGGATTATGTGAGCCGGGTTATAGCAGTAGCAGGT
GATCGTGTTACCTATATGGACGATATTTTTTACCTGAACAATATGGTTGAATCTCAATCCTATCTTGAGAGTATGAAGGC
AAAGTATCTCAATCATGCCCCTATTGGTACGCTTTATACGGAGGATTTTACGATTTCGACGGTTACTTCTGGAAAATACG
ATAGCATTCCCAAGGGGAAATACCTTTTGCTAAATGATAACAGAAAAAACCATCATGATAGCCGTCAGTTTGGCTTAATT
GACGTGTCACAAATTAAGGGATTAGTAACATTTAGAGTGCTTCCTTTGAAAGACTTTGGATTTGTAGAGGTAGAGTAG

Upstream 100 bases:

>100_bases
CTCTATCAGATAATTTAAGGCAAACAATGATACTTAAAAATTGTTTGCTTTTTTTATTAGTCATATCATGTTATAATGAG
ACTATAGACTAGGAGTTATT

Downstream 100 bases:

>100_bases
CTTTAAGGCTGCTCTATTTTGTTTCTCAAAATATGACTATACCAATTTTCTTGTTGACAAGATTTTTCTGAAGTTATATA
CTCTAAATATAACGTTTTAG

Product: signal peptidase I LepB

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNKGDLITIKKNIEPKYKDFVVYTVDKKDYVSRVIAVAG
DRVTYMDDIFYLNNMVESQSYLESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
DVSQIKGLVTFRVLPLKDFGFVEVE

Sequences:

>Translated_185_residues
MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNKGDLITIKKNIEPKYKDFVVYTVDKKDYVSRVIAVAG
DRVTYMDDIFYLNNMVESQSYLESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
DVSQIKGLVTFRVLPLKDFGFVEVE
>Mature_185_residues
MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNKGDLITIKKNIEPKYKDFVVYTVDKKDYVSRVIAVAG
DRVTYMDDIFYLNNMVESQSYLESMKAKYLNHAPIGTLYTEDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLI
DVSQIKGLVTFRVLPLKDFGFVEVE

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019756
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 21282; Mature: 21282

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNKGDLITIKKNIEPKYKD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCCEEEEECCCCCCCCE
FVVYTVDKKDYVSRVIAVAGDRVTYMDDIFYLNNMVESQSYLESMKAKYLNHAPIGTLYT
EEEEEECCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
EDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLIDVSQIKGLVTFRVLPLKDFG
CCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEHHHHCCEEEEEEEECCCCC
FVEVE
EEEEC
>Mature Secondary Structure
MVKRDFIRNILLLLILIVGAVLLRIFVFSTYRVTSEASNAYLNKGDLITIKKNIEPKYKD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCCCEEEEECCCCCCCCE
FVVYTVDKKDYVSRVIAVAGDRVTYMDDIFYLNNMVESQSYLESMKAKYLNHAPIGTLYT
EEEEEECCHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
EDFTISTVTSGKYDSIPKGKYLLLNDNRKNHHDSRQFGLIDVSQIKGLVTFRVLPLKDFG
CCEEEEEECCCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEHHHHCCEEEEEEEECCCCC
FVEVE
EEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8801417 [H]