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The map label for this gene is ezrA [H]

Identifier: 195977900

GI number: 195977900

Start: 801001

End: 802725

Strand: Direct

Name: ezrA [H]

Synonym: Sez_0770

Alternate gene names: 195977900

Gene position: 801001-802725 (Clockwise)

Preceding gene: 195977899

Following gene: 195977901

Centisome position: 39.57

GC content: 42.09

Gene sequence:

>1725_bases
ATGTCAAGCGGACTTATCTTGCTGATTGTAGCCATAGTCTTACTAGTGATTATTGCTTATTTAGTGGGTGTTATTATACG
CAAGCGTAATGACACATTAATTACCAGTCTAGAAGAACGAAAACAAGCTTTATTTGGCCTTCCTGTTAATGACGAAATCG
AGGAAGTCAAGTCTCTTCACTTGATTGGTCAAAGCCAGACCTCATTTCGTGAATGGAATCAAAAGTGGGTTGATTTGACC
CTAAATACCTTTACCGATATTGAAAAGCATATCTTTGAAGCTGAGCACTTAAATGACACCTTTAATTTTATTCGTGCCAA
GCATGAGATTAATAGCGTTGAGAGTCAATTGAATCTGGTTGAAGAGGATATTACCGCTATTCGTGAAGCACTTGGCATAT
TAAAGGAGCAGGAAGAAAAAAACAGTGCGCGTGTTACCCATGCTCTCGATTTGTACGAAAAGCTGCAGGCATCAGTTGCT
GAGAATGAAGATAATTTCGGATCAACAATGGCCGAAATTGAAAAGCAAATGAAGAATATTGAAGCAGAATTTTCACAATT
TGTTGCCCTTAATTCATCAGGTGATCCTGTTGAAGCGGCAGAGGTTTTGGATAAGGCTGAAGAGCATACGATTGCTTTAG
GGCAAATTACAGAGCAGATCCCAGCTATTGTAGCAAAGCTTGAGGACGATTTTCCAGATCAATTGGACGATCTGGAGACA
GGCTATCGTCGTTTGCTGGAGGAAAATTATCATTTTCCAGAAAAAAATATTGAAGCCCGCTTTCAAGAGATTCGTGAGTC
TATTCGTGCCAATTCATCAGAGCTGGTTACCCTTGATTTGGACCGAGCTAGAGATGAAAATACTCACATTCAAGAGCGTA
TCGACTCACTGTATGAGCTCTTTGAGCGTGAGATTGCAGCCTACAAGGTGGTTGCTAAAAATAGCAAAATATTACCAAGA
TACCTGGCTCACGCCAAGCACAACAACGAGCAGTTGAAGCATGAGATTGCTCGTCTATCACGTAAGTATATCTTGAGTGA
AAATGAAGGCTTAAATATCAAGGCCTTTGACAAAGACCTCAAAGATATCGAAGACAATGTCCTTGAGATTGCTGAAGCCT
TTGATCAGCAGGAAAAGCCATTTTCAGAGCTACAGCTGATTCTTGATCGTAGTATCAAGACGTTGGCTTCTGTAGAGTCT
GGTCAGATGGACGTCTTTGCTGCTGTTAAAGACATTGAAAAGATTGAGTCACAGGCTCGCCAGCACTTAGAAATCTACGT
CACACAGCTTCACATGATTAAGCGTTATATGGAAAAGCGCAATTTACCGGGAATTCCGCAGGATTTTCTGAGTACCTTCT
TTACCACTAGTTCGCAGCTAGAAGCATTGATGGACGAGCTAAGCAGAGGACGCATCAACATTGAAGCGGTGTCCCGTCTG
TCTGAGGTGGCAACAGCTGCTATTGCTAATCTAGAAGAGCTAACCTACCAAGTGGTTCAGCATGCTACCTTGACAGAGCA
GCTGCTCCAGTACTCTAACCGTTATCGTTCCTTTGAAGCTGGCGTGCAAAATAGCTTTGAGCATGCTTTGAAATTGTTCG
AGGTGGACAATGACTATCAGGCATCGTTTGATGAGATTTCTTATGCCTTGGAGACAGTCGAGCCAGGAGTGACAGAGCGT
TTTGTCAATTCCTATGAAAAAACACGTGAACGTATCCGCTTCTAA

Upstream 100 bases:

>100_bases
TATAGTGTATTTTTGATAATATAATAAAAGGCGATTCTTGCTAGTTGTTCCTACTGAACCGGCAGTTGATCAATCGCATC
TAAATAATAAGGAGATTAAG

Downstream 100 bases:

>100_bases
TGTGACAAGGGCTGATACTTTATATTACGAAAAAGCTTGAAAAAGCAGTCCATGCTGGGCTATGCTTTTTCAAGCTTTTT
GAATGGTCAGGCTATGGCCT

Product: septation ring formation regulator EzrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 574; Mature: 573

Protein sequence:

>574_residues
MSSGLILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQALFGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLT
LNTFTDIEKHIFEAEHLNDTFNFIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITEQIPAIVAKLEDDFPDQLDDLET
GYRRLLEENYHFPEKNIEARFQEIRESIRANSSELVTLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPR
YLAHAKHNNEQLKHEIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSIKTLASVES
GQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFLSTFFTTSSQLEALMDELSRGRINIEAVSRL
SEVATAAIANLEELTYQVVQHATLTEQLLQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTER
FVNSYEKTRERIRF

Sequences:

>Translated_574_residues
MSSGLILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQALFGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLT
LNTFTDIEKHIFEAEHLNDTFNFIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVA
ENEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITEQIPAIVAKLEDDFPDQLDDLET
GYRRLLEENYHFPEKNIEARFQEIRESIRANSSELVTLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPR
YLAHAKHNNEQLKHEIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSIKTLASVES
GQMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFLSTFFTTSSQLEALMDELSRGRINIEAVSRL
SEVATAAIANLEELTYQVVQHATLTEQLLQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTER
FVNSYEKTRERIRF
>Mature_573_residues
SSGLILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQALFGLPVNDEIEEVKSLHLIGQSQTSFREWNQKWVDLTL
NTFTDIEKHIFEAEHLNDTFNFIRAKHEINSVESQLNLVEEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVAE
NEDNFGSTMAEIEKQMKNIEAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITEQIPAIVAKLEDDFPDQLDDLETG
YRRLLEENYHFPEKNIEARFQEIRESIRANSSELVTLDLDRARDENTHIQERIDSLYELFEREIAAYKVVAKNSKILPRY
LAHAKHNNEQLKHEIARLSRKYILSENEGLNIKAFDKDLKDIEDNVLEIAEAFDQQEKPFSELQLILDRSIKTLASVESG
QMDVFAAVKDIEKIESQARQHLEIYVTQLHMIKRYMEKRNLPGIPQDFLSTFFTTSSQLEALMDELSRGRINIEAVSRLS
EVATAAIANLEELTYQVVQHATLTEQLLQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQASFDEISYALETVEPGVTERF
VNSYEKTRERIRF

Specific function: Negative regulator of ftsZ ring formation; modulates the frequency and position of ftsZ ring formation. Inhibits ftsZ ring formation at polar sites. Interacts either with ftsZ or with one of its binding partners to promote depolymerization [H]

COG id: COG4477

COG function: function code D; Negative regulator of septation ring formation

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein. Note=Colocalized with ftsZ to the nascent septal site (By similarity) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ezrA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010379 [H]

Pfam domain/function: PF06160 EzrA [H]

EC number: NA

Molecular weight: Translated: 66076; Mature: 65945

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSGLILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQALFGLPVNDEIEEVKSLH
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFNFIRAKHEINSVESQLNLV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVAENEDNFGSTMAEIEKQMKNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
EAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITEQIPAIVAKLEDDFPDQLDDLET
HHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GYRRLLEENYHFPEKNIEARFQEIRESIRANSSELVTLDLDRARDENTHIQERIDSLYEL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHH
FEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKHEIARLSRKYILSENEGLNIKAFDKDL
HHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHH
KDIEDNVLEIAEAFDQQEKPFSELQLILDRSIKTLASVESGQMDVFAAVKDIEKIESQAR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QHLEIYVTQLHMIKRYMEKRNLPGIPQDFLSTFFTTSSQLEALMDELSRGRINIEAVSRL
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHH
SEVATAAIANLEELTYQVVQHATLTEQLLQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ASFDEISYALETVEPGVTERFVNSYEKTRERIRF
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSGLILLIVAIVLLVIIAYLVGVIIRKRNDTLITSLEERKQALFGLPVNDEIEEVKSLH
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LIGQSQTSFREWNQKWVDLTLNTFTDIEKHIFEAEHLNDTFNFIRAKHEINSVESQLNLV
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEDITAIREALGILKEQEEKNSARVTHALDLYEKLQASVAENEDNFGSTMAEIEKQMKNI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
EAEFSQFVALNSSGDPVEAAEVLDKAEEHTIALGQITEQIPAIVAKLEDDFPDQLDDLET
HHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
GYRRLLEENYHFPEKNIEARFQEIRESIRANSSELVTLDLDRARDENTHIQERIDSLYEL
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHH
FEREIAAYKVVAKNSKILPRYLAHAKHNNEQLKHEIARLSRKYILSENEGLNIKAFDKDL
HHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEHHHHH
KDIEDNVLEIAEAFDQQEKPFSELQLILDRSIKTLASVESGQMDVFAAVKDIEKIESQAR
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
QHLEIYVTQLHMIKRYMEKRNLPGIPQDFLSTFFTTSSQLEALMDELSRGRINIEAVSRL
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHH
SEVATAAIANLEELTYQVVQHATLTEQLLQYSNRYRSFEAGVQNSFEHALKLFEVDNDYQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
ASFDEISYALETVEPGVTERFVNSYEKTRERIRF
CCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA