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The map label for this gene is asnC [H]

Identifier: 195977860

GI number: 195977860

Start: 759417

End: 760763

Strand: Direct

Name: asnC [H]

Synonym: Sez_0728

Alternate gene names: 195977860

Gene position: 759417-760763 (Clockwise)

Preceding gene: 195977859

Following gene: 195977861

Centisome position: 37.52

GC content: 46.92

Gene sequence:

>1347_bases
ATGACCAAAAAATACGTTTCCATTATTGATGTTAAAGACCATGTAGGACAAGAAGTGACAGTTGGTGCTTGGGTCGCCAA
CAAGTCAGGCAAAGGGAAAATAGCCTTTTTGCAATTGCGTGATGGCTCAGCCTTTTTCCAGGCAGTTGCCTTTAAGCCAA
ACCTGATCCAAGCCTTTGGTGAGGAAGCAGGAGCAGCTAAGTTTGACACGATTAGGCATCTCAGCCAAGAAACCTCTGTC
TTAGTAAAGGGCATTGTCAAAGAGGACGCTAGATCAAAATTTGGCTATGAGCTAGACATTACGGACCTAGAGGTTATTGG
GGATTCCAAGGATTATCCAATCACTCCAAAGGAGCATGGGACAGACTTTCTCATGGATCACCGTCACCTTTGGCTGCGCT
CTCGCAGGCAGGCAGCAATCATGCAAATCCGTAATGCCATCATCTATGCTTCCTATGAGTTTTTTGATCAAAATGGCTTT
ATCAAGTTTGATAGCCCGATTTTATCAGGCAATGCTGCTGAAAACACAACAGAGCTATTTGAGACAGATTATTTTGGCAA
TCCAGCCTTTCTCAGCCAATCAGGTCAGCTATACCTTGAGGCTGGTATGATGGCGCTTGGTCGCGTCTTTGACTTTGGTC
CAGTATTTCGTGCCGAAAAATCAAAAACGCGCCGCCATCTGACAGAGTTTTGGATGATGGACGCAGAATACCCTTTCTTA
TCCCATGAGGAATCCTTAGACCTACAGGAAGCCTATGTTAAGGCGATGATTCAGGGCGTGCTTGATCGTGCCCCACAGGC
ATTGGAGCTTTTAGAGCGTGACACAGAGCTGCTGAAAAAATACATTGCAGAGCCCTTCAAGCGTGTCTCTTATGATGATG
CGATCAGCCTGCTACAGGAGCATAGCACAGATGACGATGCCGACTACGAGCCAATTCAGCATGGCGATGACTTTGGCTCA
CCGCATGAAACCTGGATTTCCAATTATTTTGGGGTCCCAACCTTTGTCATCAACTACCCAGCTAGCTTTAAGGCCTTTTA
CATGAAGCCGGTTCCCGGCAATGAAGAACGCGTGCTATGTGCGGACCTGCTAGCACCAGAGGGCTACGGTGAGATTATTG
GAGGCTCTGTTCGTGAGGATAACTATGACAAATTGTTGGCGAAAATCAAGGCTGAAGGCTTAAATCCTGAGGATTATGAC
TTTTACCTTGACCTTCGCAAATATGGTTCAGTGCCGCATGCTGGCTTTGGCCTTGGACTAGAGCGCATGGTGACCTTTGT
CGCCGGCACCAAGCACATTCGTGAAGCTATTCCATTCCCACGCATGCTTCATCGTTTAAAACCCTAA

Upstream 100 bases:

>100_bases
TGATTTGGCAACCCTAAAAGAAGCTATCAGACGACTCAATCAGTTCATGACAACTGACAGCAGCCATGACAACAAAGAGA
ATGAATAGAAAAGAGACATT

Downstream 100 bases:

>100_bases
TGAACCCTATCAGCGTCCAATCTTGGGCGCTTTTTTGTTGGACTGAGAAGCACACTTAGTACCTAAGTCTTACAGCTAGT
CTTGGTAGAGCTGTGGAGCT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSAFFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSV
LVKGIVKEDARSKFGYELDITDLEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYPFL
SHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTELLKKYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGS
PHETWISNYFGVPTFVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAEGLNPEDYD
FYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP

Sequences:

>Translated_448_residues
MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSAFFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSV
LVKGIVKEDARSKFGYELDITDLEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGF
IKFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYPFL
SHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTELLKKYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGS
PHETWISNYFGVPTFVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAEGLNPEDYD
FYLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP
>Mature_447_residues
TKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSAFFQAVAFKPNLIQAFGEEAGAAKFDTIRHLSQETSVL
VKGIVKEDARSKFGYELDITDLEVIGDSKDYPITPKEHGTDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGFI
KFDSPILSGNAAENTTELFETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYPFLS
HEESLDLQEAYVKAMIQGVLDRAPQALELLERDTELLKKYIAEPFKRVSYDDAISLLQEHSTDDDADYEPIQHGDDFGSP
HETWISNYFGVPTFVINYPASFKAFYMKPVPGNEERVLCADLLAPEGYGEIIGGSVREDNYDKLLAKIKAEGLNPEDYDF
YLDLRKYGSVPHAGFGLGLERMVTFVAGTKHIREAIPFPRMLHRLKP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI226491502, Length=453, Percent_Identity=34.6578366445916, Blast_Score=253, Evalue=2e-67,
Organism=Homo sapiens, GI4758762, Length=455, Percent_Identity=34.2857142857143, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI45439306, Length=484, Percent_Identity=27.4793388429752, Blast_Score=153, Evalue=3e-37,
Organism=Escherichia coli, GI1787161, Length=472, Percent_Identity=34.5338983050847, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI1788173, Length=261, Percent_Identity=25.2873563218391, Blast_Score=72, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71984122, Length=452, Percent_Identity=37.3893805309735, Blast_Score=263, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17556372, Length=428, Percent_Identity=29.4392523364486, Blast_Score=143, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17551876, Length=484, Percent_Identity=27.6859504132231, Blast_Score=142, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6321807, Length=448, Percent_Identity=34.375, Blast_Score=244, Evalue=1e-65,
Organism=Saccharomyces cerevisiae, GI6319872, Length=460, Percent_Identity=33.4782608695652, Blast_Score=235, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6323011, Length=488, Percent_Identity=29.7131147540984, Blast_Score=152, Evalue=8e-38,
Organism=Drosophila melanogaster, GI19921528, Length=438, Percent_Identity=34.0182648401827, Blast_Score=232, Evalue=4e-61,
Organism=Drosophila melanogaster, GI19922416, Length=464, Percent_Identity=31.6810344827586, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI17136276, Length=475, Percent_Identity=26.3157894736842, Blast_Score=136, Evalue=3e-32,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 50785; Mature: 50654

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSAFFQAVAFKPNLIQAFG
CCCCEEEEEECHHHCCCEEEEEEEEECCCCCCCEEEEEEECCCHHHHHHHCCCHHHHHHC
EEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITDLEVIGDSKDYPITPKEHG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCCCCCCCCCCC
TDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGFIKFDSPILSGNAAENTTELF
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEECCCEECCCCCCCHHHHH
ETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYPFL
HHCCCCCCCEECCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
SHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTELLKKYIAEPFKRVSYDDAISLLQE
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HSTDDDADYEPIQHGDDFGSPHETWISNYFGVPTFVINYPASFKAFYMKPVPGNEERVLC
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCEEE
ADLLAPEGYGEIIGGSVREDNYDKLLAKIKAEGLNPEDYDFYLDLRKYGSVPHAGFGLGL
HHHHCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHCCCCCCCCCCCH
ERMVTFVAGTKHIREAIPFPRMLHRLKP
HHHHHHHHHHHHHHHHCCHHHHHHHCCC
>Mature Secondary Structure 
TKKYVSIIDVKDHVGQEVTVGAWVANKSGKGKIAFLQLRDGSAFFQAVAFKPNLIQAFG
CCCEEEEEECHHHCCCEEEEEEEEECCCCCCCEEEEEEECCCHHHHHHHCCCHHHHHHC
EEAGAAKFDTIRHLSQETSVLVKGIVKEDARSKFGYELDITDLEVIGDSKDYPITPKEHG
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCCCCCCCCCCC
TDFLMDHRHLWLRSRRQAAIMQIRNAIIYASYEFFDQNGFIKFDSPILSGNAAENTTELF
CHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEECCCCEEEECCCEECCCCCCCHHHHH
ETDYFGNPAFLSQSGQLYLEAGMMALGRVFDFGPVFRAEKSKTRRHLTEFWMMDAEYPFL
HHCCCCCCCEECCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
SHEESLDLQEAYVKAMIQGVLDRAPQALELLERDTELLKKYIAEPFKRVSYDDAISLLQE
CCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
HSTDDDADYEPIQHGDDFGSPHETWISNYFGVPTFVINYPASFKAFYMKPVPGNEERVLC
CCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCEEE
ADLLAPEGYGEIIGGSVREDNYDKLLAKIKAEGLNPEDYDFYLDLRKYGSVPHAGFGLGL
HHHHCCCCCCHHCCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHCCCCCCCCCCCH
ERMVTFVAGTKHIREAIPFPRMLHRLKP
HHHHHHHHHHHHHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12397186 [H]